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List of works by Boris Fehse

5-azacytidine promotes an inhibitory T-cell phenotype and impairs immune mediated antileukemic activity.

scientific article published on 13 March 2014

A High-Throughput HIV-1 Drug Screening Platform, Based on Lentiviral Vectors and Compatible with Biosafety Level-1

scientific article published on 25 May 2020

A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.

scientific article published on 12 February 2008

A new system for parallel drug screening against multiple-resistant HIV mutants based on lentiviral self-inactivating (SIN) vectors and multi-colour analyses

scientific article

A novel 'sort-suicide' fusion gene vector for T cell manipulation

scientific article published in December 2002

Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance

scientific article

Accurate In-Vivo Quantification of CD19 CAR-T Cells after Treatment with Axicabtagene Ciloleucel (Axi-Cel) and Tisagenlecleucel (Tisa-Cel) Using Digital PCR

scientific article published on 20 July 2020

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.

scientific article published on 15 December 2011

Aldehyde dehydrogenase activity as a marker for the quality of hematopoietic stem cell transplants

scientific article

Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

scientific article published on 26 April 2016

Analysis of progenitor cell mobilization and erythropoietin plasma levels in patients with acute myocardial infarction.

scientific article published on January 2005

Anti-thymocyte globulin overcomes the negative impact of HLA mismatching in transplantation from unrelated donors

scientific article published on 05 May 2008

Anticancer effects of the nitric oxide-modified saquinavir derivative saquinavir-NO against multidrug-resistant cancer cells

scientific article

Antithymocyte globulin induces complement-dependent cell lysis and caspase-dependent apoptosis in myeloma cells

scientific article published on 01 December 2005

Antithymocyte globulin induces ex vivo and in vivo depletion of myeloid and plasmacytoid dendritic cells

scientific article published on 01 February 2005

Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma

scientific article

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

scientific article published on 27 August 2013

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism

scientific article published on 19 May 2014

Bone marrow mesenchymal stromal cells remain of recipient origin after allogeneic SCT and do not harbor the JAK2V617F mutation in patients with myelofibrosis.

scientific article

CBIO-13CO-DELIVERY OF EGFR AND HSV-tk BY LCMV-PSEUDOTYPED BICISTRONIC LENTIVIRAL VECTORS TO ENHANCE THERAPEUTIC GENE DISTRIBUTION FOR GLIOBLASTOMA TREATMENT.

scientific article

CD133 marks a stem cell population that drives human primary myelofibrosis

scientific article published on 27 February 2015

CD34 modulates the trafficking behavior of hematopoietic cells in vivo

scientific article (publication date: April 2007)

CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation

scientific article published on 20 February 2008

Cancer Cells Expressing Oncogenic Rat Sarcoma Show Drug-Addiction Toward Epidermal Growth Factor Receptor Antibodies Mediated by Sustained MAPK Signaling

scientific article published on 01 January 2019

Cancer Suicide Gene Therapy with TK.007

scientific article published on 01 January 2019

Cancer suicide gene therapy with TK.007: superior killing efficiency and bystander effect

scientific article

Cancer-testis antigen MAGE-C2/CT10 induces spontaneous CD4+ and CD8+ T-cell responses in multiple myeloma patients

scientific article published on 9 May 2014

Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).

scientific article published in November 2010

Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma ⬇️

scientific article published on 01 November 2018

Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.

scientific article published on 28 December 2016

Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

scientific article published on January 2004

Characterization of cell types during rat liver development

scientific article published in January 2003

Chimerism studies with quantitative real-time PCR in stem cell recipients with acute myeloid leukemia

scientific article published on 17 September 2010

Clinical application of a retroviral gene transfer protocol based on centrifugation-mediated vector preloading

scientific article published on 01 June 2008

Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion.

scientific article

Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking.

scientific article

Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks.

scientific article published on 18 June 2018

Clonal evolution after allogeneic stem cell transplantation: the case of myelofibrosis

scientific article published on 05 March 2020

Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity.

scientific article

Comparative clonal analysis of reconstitution kinetics after transplantation of hematopoietic stem cells gene marked with a lentiviral SIN or a γ-retroviral LTR vector

scientific article

Comparison of two doses of antithymocyte globulin in patients undergoing matched unrelated donor allogeneic stem cell transplantation

scientific article published on 01 August 2008

Complement-dependent and complement-independent cytotoxicity of polyclonal antithymocyte globulins in chronic lymphocytic leukemia

scientific article published on 04 February 2008

Concordance of assays designed for the quantification of JAK2V617F: a multicenter study

scientific article

Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

article

Control of bone formation by the serpentine receptor Frizzled-9 ⬇️

scientific journal article

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs

scientific article published on March 2015

DRES-12. SINGLE CELL CLONAL ANALYSIS OF GBM TUMOR HIERARCHIES USING OPTICAL BARCODING

scientific article published on 6 November 2017

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL.

scientific article

Development of CAR-T cell therapies for multiple myeloma

scientific article published on 22 June 2020

Differences in proportion and dynamics of recipient hematopoiesis following hematopoietic cell transplantation in CML and IMF

scientific article published on 01 January 2008

Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel

scientific article published on 15 January 2020

Digital PCR Panel for Sensitive Hematopoietic Chimerism Quantification after Allogeneic Stem Cell Transplantation

scientific article published on 09 September 2016

Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases.

scientific article published on 25 February 2016

Digital PCR to assess hematopoietic chimerism after allogeneic stem cell transplantation

scientific article published on 18 March 2015

Digital-PCR assay for screening and quantitative monitoring of calreticulin (CALR) type-2 positive patients with myelofibrosis following allogeneic stem cell transplantation.

scientific article published on 15 February 2016

Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients.

scientific article published on 22 June 2015

Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population

scientific article published on 24 July 2003

EXTH-68. RECURRENT XENOGRAFT TUMORS UPREGULATE EGFR AFTER LENTIVIRAL VECTOR MEDIATED SUICIDE GENE THERAPY FOR GLIOBLASTOMA, BUT ARE RESISTANT TO COMBINATORIAL TREATMENT WITH ERLOTINIB

Efficient depletion of alloreactive donor T lymphocytes based on expression of two activation-induced antigens (CD25 and CD69).

scientific article published on June 2000

Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers

scientific article published on 13 September 2017

Efficient lentiviral transduction and transgene expression in primary human B cells

scientific article published on December 2012

Endogenous retrovirus induces leukemia in a xenograft mouse model for primary myelofibrosis.

scientific article

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer.

scientific article published in May 2015

Erratum: RGB marking with lentiviral vectors for multicolor clonal cell tracking

scientific article published on 28 May 2015

Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements

scientific article published in October 1999

Evidence for increased risk of secondary graft failure after in vivo depletion of suicide gene-modified T lymphocytes transplanted in conjunction with CD34+-enriched blood stem cells

scientific article published on 01 November 2004

Excellent proliferation and persistence of allogeneic donor-derived 41-BB based CAR-T cells despite immunosuppression with cyclosporine A

scientific article published on 02 April 2020

Excision of specific DNA-sequences from integrated retroviral vectors via site-specific recombination

scientific article published on November 1995

Fucoidans as potential inhibitors of HIV-1.

scientific article published on 19 August 2013

Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL-positive CML cells

scientific article published on 30 October 2010

Gene and Cell Therapy in Germany

scientific article published in October 2017

Gene therapy strategies: can we eradicate HIV?

scientific article

Gene transfer of SHIP-1 inhibits proliferation of juvenile myelomonocytic leukemia cells carrying KRAS2 or PTPN11 mutations

scientific article published in February 2007

Genetic Barcodes Facilitate Competitive Clonal Analyses In Vivo.

scientific article published on 28 August 2017

Genetically modified neural stem cells for a local and sustained delivery of neuroprotective factors to the dystrophic mouse retina

scientific article published on 28 October 2013

Glioma escape signature and clonal development under immune pressure

scientific article published on 30 June 2020

Hepatic lineages isolated from developing rat liver show different ways of maturation

scientific article published in May 2003

Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo

scientific article published on 7 December 2017

High Bone Turnover in Mice Carrying a Pathogenic Notch2 Mutation Causing Hajdu-Cheney Syndrome.

scientific article published on 30 August 2017

Highly efficient lentiviral transduction of phenotypically and genotypically characterized endothelial progenitor cells from adult peripheral blood.

scientific article published on July 2010

Highly efficient retroviral gene transfer based on centrifugation-mediated vector preloading of tissue culture vessels

scientific article published on April 2002

Human mesenchymal stem cells are not of donor origin in patients with severe aplastic anemia who underwent sex-mismatched allogeneic bone marrow transplant

scientific article published on 01 December 2002

IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis

scientific article published on 2 February 2017

IMMU-44. OPTICAL BARCODING TO INVESTIGATE CLONAL DYNAMICS OF GBM HIGHLIGHTS THE INTRINSIC CAPACITY OF GBM TO RE-ACTIVATE DEVELOPMENTAL GENES AND ESCAPE IMMUNE SURVEILLANCE

scientific article published on 5 November 2018

IMMU-62. OPTICAL BARCODING REVEALS IMMUNOEDITING OF THE CLONAL ARCHITECTURE AND MODULATION OF GENE EXPRESSION SIGNATURES IN A SYNGENEIC GLIOMA MODEL

Identification of the adult human hemangioblast

scientific article

Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

scientific article published on 21 March 2019

Impact of JAK2V617F mutation status, allele burden, and clearance after allogeneic stem cell transplantation for myelofibrosis

scientific article published on 20 May 2010

Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation

scientific article published on 04 April 2017

Impact of high-risk cytogenetics and achievement of molecular remission on long-term freedom from disease after autologous-allogeneic tandem transplantation in patients with multiple myeloma

scientific article published on 16 October 2012

Impact of molecular residual disease post allografting in myelofibrosis patients

scientific article published on 17 July 2017

Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I.

scientific article

Improving the ex vivo retroviral-mediated suicide-gene transfer process in T lymphocytes to preserve immune function.

scientific article

In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets

scientific article published on 27 September 2021

In-vivo RGB marking and multicolour single-cell tracking in the adult brain

scientific article

Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation

scientific article published on 01 April 2003

Influence of mannose-binding lectin genotypes and serostatus in allo-SCT: analysis of 131 recipients and donors.

scientific article

Influenza virus-specific TCR-transduced T cells as a model for adoptive immunotherapy

scientific article published on 21 February 2013

Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene

scientific article published on 29 March 2007

Intravitreal Co-Administration of GDNF and CNTF Confers Synergistic and Long-Lasting Protection against Injury-Induced Cell Death of Retinal Ganglion Cells in Mice

scientific article published on 11 September 2020

Investigation of the Mesenchymal Stem Cell Compartment by Means of a Lentiviral Barcode Library

scientific article

Is multiple sclerosis progression associated with the HLA-DR15 haplotype?

scientific article published on 01 October 2019

JAK2-V617F-triggered preemptive and salvage adoptive immunotherapy with donor-lymphocyte infusion in patients with myelofibrosis after allogeneic stem cell transplantation

scientific article published in February 2009

Kinetics of plasma-cell chimerism after allogeneic stem cell transplantation by highly sensitive real-time PCR based on sequence polymorphism and its value to quantify minimal residual disease in patients with multiple myeloma

scientific article published in May 2006

Lenalidomide as salvage therapy after allo-SCT for multiple myeloma is effective and leads to an increase of activated NK (NKp44(+)) and T (HLA-DR(+)) cells

scientific article

Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells

scientific article published on 4 August 2016

Lentiviral gene ontology (LeGO) vectors equipped with novel drug-selectable fluorescent proteins: new building blocks for cell marking and multi-gene analysis.

scientific article published on 17 December 2009

Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis.

scientific article

Limitations and challenges of genetic barcode quantification

scientific article

Liver-specific gene expression in cultured human hematopoietic stem cells.

scientific article

Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models.

scientific article published on 6 December 2017

Long-term in vivo single-cell tracking reveals the switch of migration patterns in adult-born juxtaglomerular cells of the mouse olfactory bulb

scientific article

Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma

scientific article published on 01 July 2019

Low frequency of calreticulin mutations in MDS patients

scientific article published on 21 May 2014

Low-dose thalidomide and donor lymphocyte infusion as adoptive immunotherapy after allogeneic stem cell transplantation in patients with multiple myeloma.

scientific article

Mammary epithelial reconstitution with gene-modified stem cells assigns roles to Stat5 in luminal alveolar cell fate decisions, differentiation, involution, and mammary tumor formation

scientific article published in May 2010

Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology

scientific article published on 31 March 2016

Membrane-anchored peptide inhibits human immunodeficiency virus entry

scientific article

Mesenchymal Stromal/Stem Cells Do Not Ameliorate Experimental Autoimmune Encephalomyelitis and Are Not Detectable in the Central Nervous System of Transplanted Mice

scientific article published on June 2016

Microglia regulate hippocampal neurogenesis during chronic neurodegeneration ⬇️

scientific article

Minimal residual disease diagnostics and chimerism in the post-transplant period in acute myeloid leukemia.

scientific article published on 3 February 2011

Minimal residual disease diagnostics in patients with acute myeloid leukemia in the post-transplant period: comparison of peripheral blood and bone marrow analysis

scientific article published on 01 October 2010

Molecular methods for detection and quantification of myeloma cells after bone marrow transplantation: comparison between real-time quantitative and nested PCR.

scientific article

Monitoring of minimal residual disease in multiple myeloma after allo-SCT: flow cytometry vs PCR-based techniques.

scientific article

Monitoring of the JAK2-V617F mutation by highly sensitive quantitative real-time PCR after allogeneic stem cell transplantation in patients with myelofibrosis.

scientific article published on 3 October 2006

Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model.

scientific article published on 14 December 2017

Multicolor RGB Marking Allows Morphometric and Functional Analysis of Hippocampal Granule Neurons at the Single-Cell Level

scientific article published on 20 April 2015

Multiple genes surrounding Bcl-xL, a common retroviral insertion site, can influence hematopoiesis individually or in concert

scientific article published on 03 October 2020

Multiplexing clonality: combining RGB marking and genetic barcoding.

scientific article published on 29 January 2014

Murine leukemia induced by retroviral gene marking

scientific article published on 01 April 2002

Mutagenesis and oncogenesis by chromosomal insertion of gene transfer vectors.

scientific article

Mutagenesis by retroviral transgene insertion: risk assessment and potential alternatives.

scientific article published on October 2003

Nanobody Targeting of Epidermal Growth Factor Receptor (EGFR) Ectodomain Variants Overcomes Resistance to Therapeutic EGFR Antibodies

scientific article published on 01 March 2019

Nanobody-based CD38-specific heavy chain antibodies induce killing of multiple myeloma and other hematological malignancies

scientific article published on 03 February 2020

Neural stem cell-based intraocular administration of ciliary neurotrophic factor attenuates the loss of axotomized ganglion cells in adult mice

scientific article published on 30 September 2014

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

scientific article

Obituary Rolf Neth 1926-2020

scientific article published on 10 April 2020

Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity

scientific article published on 18 January 2017

Overcoming the delivery problem for therapeutic genome editing: Current status and perspective of non-viral methods

scientific article published on 06 August 2020

Overexpression of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase inhibits GM-CSF-dependent colony formation of CD34+ hematopoietic progenitor cells

scientific article published on June 2008

Persisting multilineage transgene expression in the clonal progeny of a hematopoietic stem cell

scientific article published in September 2002

Pilot study of reduced-intensity conditioning followed by allogeneic stem cell transplantation from related and unrelated donors in patients with myelofibrosis

scientific article

Post-transplant immunotherapy with donor-lymphocyte infusion and novel agents to upgrade partial into complete and molecular remission in allografted patients with multiple myeloma.

scientific article published on 31 May 2009

Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins

scientific article published on 22 August 2016

Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose

scientific article published in December 2003

Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer.

scientific article published on 11 April 2016

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene

scientific article

Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation

scientific article published on 07 February 2014

Purification of CD4+ T cells for adoptive immunotherapy after allogeneic hematopoietic stem cell transplantation

scientific article published on 15 July 2010

Quantitative monitoring of NPM1 mutations provides a valid minimal residual disease parameter following allogeneic stem cell transplantation.

scientific article

REPEATED INTRANASAL APPLICATION OF NEURAL STEM CELL-MEDIATED ENZYM/PRODRUG THERAPY USING A NOVEL HSV-THYMIDINE KINASE VARIANT IMPROVES THERAPEUTIC EFFICIENCY IN AN INTRACRANIAL GLIOBLASTOMA MODEL.

scientific article published in July 2014

RGB marking facilitates multicolor clonal cell tracking

scientific article published on 27 March 2011

RGB marking with lentiviral vectors for multicolor clonal cell tracking

scientific article published on 05 April 2012

Rapid and efficient cloning of proviral flanking fragments by kanamycin resistance gene complementation

scientific article published on January 1999

Real-time quantitative Y chromosome-specific PCR (QYCS-PCR) for monitoring hematopoietic chimerism after sex-mismatched allogeneic stem cell transplantation

scientific article published in June 2001

Reduced proliferation of CD34(+) cells from patients with acute myeloid leukemia after gene transfer of INPP5D.

scientific article

Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA

scientific article published on 02 August 2007

Resistance of mature T cells to oncogene transformation

scientific article

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle

scientific article published on November 2004

Retroviral insertion site analysis in dominant haematopoietic clones

scientific article published in January 2009

Retroviral insertional mutagenesis can contribute to immortalization of mature T lymphocytes

scientific article

Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis

scientific article published on 13 January 2014

Retroviral integration site analysis in hematopoietic stem cells

scientific article published in January 2008

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

scientific article published on 21 November 2006

Retroviral vector insertions in T-lymphocytes used for suicide gene therapy occur in gene groups with specific molecular functions

scientific article published on 19 June 2006

Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.

scientific article

Role of Growth arrest-specific gene 6-Mer axis in multiple myeloma.

scientific article

SC-07CYCLIC INTRANASAL APPLICATION OF NEURAL STEM CELL-MEDIATED ENZYM/PRODRUG THERAPY USING A NOVEL HSV-THYMIDINE KINASE VARIANT INHIBITS INTRACEREBRAL GLIOMA GROWTH AND IMPROVES SURVIVAL.

scientific article published in November 2014

SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model

scientific article published on 16 November 2017

SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2

scientific article published on 21 August 2020

SOCS3 promotes interleukin-17 expression of human T cells

scientific article published on October 2012

Screening and monitoring of MPL W515L mutation with real-time PCR in patients with myelofibrosis undergoing allogeneic-SCT

scientific article published on 11 January 2010

Screening of Potential HIV-1 Inhibitors/Replication Blockers Using Secure Lentiviral in Vitro System

scientific article published on October 2011

Selectins mediate small cell lung cancer systemic metastasis

scientific article (publication date: 2014)

Self-inactivating retroviral vectors with improved RNA processing.

scientific article published on November 2004

Sensitive balance of suppressing and activating effects of mesenchymal stem cells on T-cell proliferation

scientific article published on 01 November 2006

Side effects of retroviral gene transfer into hematopoietic stem cells

scientific article

Similar outcome of calreticulin type I and calreticulin type II mutations following RIC allogeneic haematopoietic stem cell transplantation for myelofibrosis

scientific article published on 23 May 2016

Simplified generation of high-titer retrovirus producer cells for clinically relevant retroviral vectors by reversible inclusion of a lox-P-flanked marker gene

scientific article

Stem cell clonality and genotoxicity in hematopoietic cells: gene activation side effects should be avoidable.

scientific article published in October 2004

Stem cell marking with promotor-deprived self-inactivating retroviral vectors does not lead to induced clonal imbalance

scientific article

Suicide gene therapy for the treatment of high-grade glioma: past lessons, present trends, and future prospects

scientific article published on 01 January 2020

TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer

scientific article published on 27 March 2014

TK.007: A novel, codon-optimized HSVtk(A168H) mutant for suicide gene therapy

scientific article

Targeting CD38-Expressing Multiple Myeloma and Burkitt Lymphoma Cells In Vitro with Nanobody-Based Chimeric Antigen Receptors (Nb-CARs)

scientific article published on 29 January 2020

Targeting species D adenoviruses replication to counteract the epidemic keratoconjunctivitis

scientific article published on 19 March 2015

Temporal dynamics of hippocampal neurogenesis in chronic neurodegeneration.

scientific article

The Time Is Ripe for Somatic Genome Editing: NIH Program to Strengthen Translation

scientific article published on 21 February 2018

The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.

scientific article

The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia

scientific article published on 23 February 2018

Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout

article

Transportation and cryopreservation may impair haematopoietic stem cell function and engraftment of allogeneic PBSCs, but not BM

scientific article published on 07 April 2008

Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors.

scientific article

Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors.

scientific article published on 2 June 2015

Tumor cells escape suicide gene therapy by genetic and epigenetic instability

scientific article published on 12 August 2004

Universal modular system for in vitro screening of potential inhibitors of HIV-1 replication

scientific article published in March 2014

Unrelated stem cell transplantation in multiple myeloma after a reduced-intensity conditioning with pretransplantation antithymocyte globulin is highly effective with low transplantation-related mortality

scientific article published on 8 August 2002

Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells

scientific article published in September 2002

mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5.

scientific article published on 11 May 2015

p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts

scientific article

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