Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Seyed Moein Moghimi

A rally for brain targeting: the advent of a new era

scientific article published on 17 June 2020

A single dose of intravenously injected poloxamine-coated long-circulating particles triggers macrophage clearance of subsequent doses in rats

scientific article published in October 1997

A special issue on nano- and micro-technologies for biological targeting, tracking, imaging and sensing

scientific article published in December 2009

A structurally diverse library of safe-by-design citrem-phospholipid lamellar and non-lamellar liquid crystalline nano-assemblies

scientific article

AFM visualization of sub-50nm polyplex disposition to the nuclear pore complex without compromising the integrity of the nuclear envelope.

scientific article published on 11 November 2016

Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking

scientific article published on 10 October 2016

Activation of the mononuclear phagocyte system by poloxamine 908: its implications for targeted drug delivery

scientific article published on 01 November 1997

Advanced colloid-based systems for efficient delivery of drugs and diagnostic agents to the lymphatic tissues

scientific article published on January 1996

Altered tissue-specific opsonic activities and opsono-recognition of liposomes in tumour-bearing rats

scientific article published on 01 November 1996

An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil®, Caelyx®, DOXOrubicin, and SinaDoxosome

scientific article

An investigation of the filtration capacity and the fate of large filtered sterically-stabilized microspheres in rat spleen

scientific article published on 01 July 1993

Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes

scientific article published on 01 May 1997

Bionanotechnologies for treatment and diagnosis of Alzheimer's disease ⬇️

scientific article published on May 17, 2011

Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes

scientific article

C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes

scientific article published on 23 May 2018

CAR T-cell bioengineering: Single variable domain of heavy chain antibody targeted CARs

scientific article published on 01 February 2019

Calcium as a possible modulator of Kupffer cell phagocytic function by regulating liver-specific opsonic activity

scientific article published on 01 October 1990

Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies

scientific article published on August 2016

Cancer nanomedicine and the complement system activation paradigm: anaphylaxis and tumour growth.

scientific article published on 16 April 2014

Capture of stealth nanoparticles by the body's defences.

scientific article

Cationic carriers of genetic material and cell death: a mitochondrial tale.

scientific article published on 08 April 2010

Causative factors behind poloxamer 188 (Pluronic F68, Flocor)-induced complement activation in human sera. A protective role against poloxamer-mediated complement activation by elevated serum lipoprotein levels

scientific article

Cellular distribution of nonionic micelles.

scientific article published in January 2004

Chemical camouflage of nanospheres with a poorly reactive surface: towards development of stealth and target-specific nanocarriers

scientific article

Cisplatin Encapsulation Generates Morphologically Different Multicompartments in the Internal Nanostructures of Nonlamellar Liquid-Crystalline Self-Assemblies

scientific article published on 24 May 2018

Citrem modulates internal nanostructure of glyceryl monooleate dispersions and bypasses complement activation: Towards development of safe tunable intravenous lipid nanocarriers

scientific article published on 5 September 2015

Coating particles with a block co-polymer (poloxamine-908) suppresses opsonization but permits the activity of dysopsonins in the serum

scientific article published on 01 November 1993

Combined Fluorimetric Caspase-3/7 Assay and Bradford Protein Determination for Assessment of Polycation-Mediated Cytotoxicity

scientific article published on 01 January 2019

Combined fluorimetric caspase 3/7 assay and bradford protein determination for assessment of polycation-mediated cytotoxicity.

scientific article published in January 2013

Complement Propriety and Conspiracy in Nanomedicine: Perspective and a Hypothesis

scientific article published on 31 December 2015

Complement activation by PEG-functionalized multi-walled carbon nanotubes is independent of PEG molecular mass and surface density.

scientific article published on 19 February 2013

Complement activation cascade triggered by PEG-PL engineered nanomedicines and carbon nanotubes: the challenges ahead

scientific article published on 11 April 2010

Complement activation turnover on surfaces of nanoparticles.

scientific article published on 12 April 2017

Complement monitoring of Pluronic 127 gel and micelles: suppression of copolymer-mediated complement activation by elevated serum levels of HDL, LDL, and apolipoproteins AI and B-100.

scientific article published on 4 June 2013

Complement monitoring of carbon nanotubes

scientific article published on 01 June 2010

Complement monitoring of nanomedicines and implants ⬇️

scientific article published on June 29, 2011

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

scientific article published on 19 December 2016

Complement system and the brain: Selected pathologies and avenues toward engineering of neurological nanomedicines ⬇️

scientific article published on November 7, 2011

Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55

scientific article published on 08 April 2019

Complement-mediated tumour growth: implications for cancer nanotechnology and nanomedicines

scientific article published on 14 March 2009

Complement: alive and kicking nanomedicines.

scientific article published on August 2009

Concentration dependent structural ordering of poloxamine 908 on polystyrene nanoparticles and their modulatory role on complement consumption

scientific article published on 01 September 2006

Critical issues in site-specific targeting of solid tumours: the carrier, the tumour barriers and the bioavailable drug.

scientific article published on February 2008

Crossing the blood-brain-barrier with nanoligand drug carriers self-assembled from a phage display peptide

scientific article published on 11 October 2019

Cubosomes and hexosomes as versatile platforms for drug delivery.

scientific article

Current progress and future prospects of liposomes in dermal drug delivery

scientific article

Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking

scientific article published on 11 August 2021

Dendrimers in Medicine: Therapeutic Concepts and Pharmaceutical Challenges.

scientific article published on 13 February 2015

Determination of Polycation-Mediated Perturbation of Mitochondrial Respiration in Intact Cells by High-Resolution Respirometry (Oxygraph-2k, OROBOROS)

scientific article published on 01 January 2019

Differential Modulation of Cellular Bioenergetics by Poly(L-lysine)s of Different Molecular Weights

scientific article published on 22 June 2015

Differential properties of organ-specific serum opsonins for liver and spleen macrophages

scientific article

Distinct polymer architecture mediates switching of complement activation pathways at the nanosphere-serum interface: implications for stealth nanoparticle engineering

scientific article published on 28 October 2010

Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene.

scientific article published on April 2013

Effect of splenic congestion associated with haemolytic anaemia on filtration of 'spleen-homing' microspheres

scientific article published on 01 June 1993

Endothelial cells as therapeutic targets in cancer: new biology and novel delivery systems.

scientific article

Engineering liposomes and nanoparticles for biological targeting.

scientific article published on January 2011

Enhanced hepatic clearance of intravenously administered sterically stabilized microspheres in zymosan-stimulated rats

scientific article published on 01 December 1993

Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide

scientific article

Genetically engineered T cells bearing chimeric nanoconstructed receptors harboring TAG-72-specific camelid single domain antibodies as targeting agents.

scientific article

Genomic perspectives in inter-individual adverse responses following nanomedicine administration: The way forward ⬇️

scientific article published on May 23, 2012

Heavy Chain Only Antibodies: A New Paradigm in Personalized HER2+ Breast Cancer Therapy.

scientific article published on 27 January 2013

High resolution respirometry analysis of polyethylenimine-mediated mitochondrial energy crisis and cellular stress: Mitochondrial proton leak and inhibition of the electron transport system

scientific article published on 11 July 2013

Humoral-mediated recognition of 'phagocyte-resistant' beads by lymph node macrophages of poloxamine-treated rats

scientific article published on 01 September 1998

Hyaluronan-coated nanoparticles: the influence of the molecular weight on CD44-hyaluronan interactions and on the immune response.

scientific article

ImmunoPEGliposome-mediated reduction of blood and brain amyloid levels in a mouse model of Alzheimer's disease is restricted to aged animals

scientific article published on 2 August 2016

Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

scientific article published on 14 January 2019

In Vitro and In Vivo Differences in Murine Third Complement Component (C3) Opsonization and Macrophage/Leukocyte Responses to Antibody-Functionalized Iron Oxide Nanoworms

scientific article

Innovations in avoiding particle clearance from blood by Kupffer cells: cause for reflection.

scientific article

Interaction of extremophilic archaeal viruses with human and mouse complement system and viral biodistribution in mice.

scientific article

Just so stories: the random acts of anti-cancer nanomedicine performance

scientific article

Lactate Dehydrogenase Assay for Assessment of Polycation Cytotoxicity

scientific article published on 01 January 2019

Lactate dehydrogenase assay for assessment of polycation cytotoxicity.

scientific article

Lipid-based nanosystems and complexes in experimental and clinical therapeutics

scientific article published on 01 October 2005

Liposome recognition by resident and newly recruited murine liver macrophages

scientific article published in February 2002

Liposome triggering of innate immune responses: a perspective on benefits and adverse reactions.

scientific article published on January 2009

Liposome-mediated triggering of complement cascade

scientific article published on 01 January 2008

Live-cell fluorescent microscopy platforms for real-time monitoring of polyplex-cell interaction: basic guidelines

scientific article published on 18 February 2014

Low and high molecular weight poly(L-lysine)s/poly(L-lysine)-DNA complexes initiate mitochondrial-mediated apoptosis differently.

scientific article

Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions

scientific article

Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum

scientific article published on 26 November 2014

Methylation of the phosphate oxygen moiety of phospholipid-methoxy(polyethylene glycol) conjugate prevents PEGylated liposome-mediated complement activation and anaphylatoxin production

scientific article published on 25 October 2006

Modification of the Stewart biphasic colorimetric assay for stable and accurate quantitative determination of Pluronic and Tetronic block copolymers for application in biological systems

scientific article published on 20 December 2006

Modulation of lymphatic distribution of subcutaneously injected poloxamer 407-coated nanospheres: the effect of the ethylene oxide chain configuration

scientific article published in April 2003

Modulation of murine liver macrophage clearance of liposomes by diethylstilbestrol. The effect of vesicle surface charge and a role for the complement receptor Mac-1 (CD11b/CD18) of newly recruited macrophages in liposome recognition

scientific article published in January 2002

Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake.

scientific article published on 21 October 2015

Modulatory effect of human plasma on the internal nanostructure and size characteristics of liquid-crystalline nanocarriers

scientific article published on 30 April 2015

Multivalent targeting and killing of HER2 overexpressing breast carcinoma cells with methotrexate-encapsulated tetra-specific non-overlapping variable domain heavy chain anti-HER2 antibody-PEG-liposomes: In vitro proof-of-concept

scientific article published on 19 June 2018

Nanomedicine and the complement paradigm

scientific article published on 14 March 2013

Nanomedicine: current status and future prospects.

scientific article

Nanoparticle Technology: Having Impact, but Needing Further Optimization.

scientific article published on 16 June 2017

Nanoparticle patterning for biomedicine

scientific article published on 28 December 2016

Nanoparticle transport pathways into tumors.

scientific article

Nanoparticles and innate immunity: new perspectives on host defence

scientific article published on 28 August 2017

Nanotechnology: from fundamental concepts to clinical applications for healthy aging

scientific article published on 19 June 2012

Nanotechnology: from fundamental concepts to clinical applications for healthy aging

scientific article published on 27 July 2012

New platforms for multi-functional ocular lenses: engineering double-sided functionalized nano-coatings.

scientific article

Non-Lamellar Liquid Crystalline Nanocarriers for Thymoquinone Encapsulation

scientific article published on 19 December 2019

Non-phagocytic uptake of intravenously injected microspheres in rat spleen: influence of particle size and hydrophilic coating

scientific article

On the issue of transparency and reproducibility in nanomedicine

scientific article published on 01 July 2019

Opsonophagocytosis of liposomes by peritoneal macrophages and bone marrow reticuloendothelial cells

scientific article published in June 1992

Ordering of Binary Polymeric Nanoparticles on Hydrophobic Surfaces Assembled from Low Volume Fraction Dispersions

scientific article published on 11 October 2007

PEGylated nanoparticles bind to and alter amyloid-beta peptide conformation: toward engineering of functional nanomedicines for Alzheimer's disease

scientific article published on 19 June 2012

PEGylation of microspheres generates a heterogeneous population of particles with differential surface characteristics and biological performance.

scientific article published on December 2002

Particulate nanomedicine in the footsteps of platelet homing

scientific article published on 01 June 2007

Particulate nanomedicines

scientific article published on 01 November 2006

Particulate systems for targeting of macrophages: basic and therapeutic concepts.

scientific article published on 19 June 2012

Peptide and nucleic acid-directed self-assembly of cationic nanovehicles through giant unilamellar vesicle modification: Targetable nanocomplexes for in vivo nucleic acid delivery

scientific article published on 18 January 2017

Perspectives on carbon nanotube-mediated adverse immune effects.

scientific article published on 23 May 2012

Perturbation of mitochondrial bioenergetics by polycations counteracts resistance to BRAFE600 inhibition in melanoma cells

scientific article published on 23 July 2019

Pharmacokinetic analysis reveals limitations and opportunities for nanomedicine targeting of endothelial and extravascular compartments of tumours

scientific article published on 04 February 2019

Platelet mimicry: The emperor's new clothes?

scientific article

Poloxamer-188 revisited: a potentially valuable immune modulator

scientific article published on 01 June 1996

Poloxamers and poloxamines in nanoparticle engineering and experimental medicine.

scientific article

Poly(3-hydroxybutyrate-co-R-3-hydroxyhexanoate) nanoparticles with polyethylenimine coat as simple, safe, and versatile vehicles for cell targeting: population characteristics, cell uptake, and intracellular trafficking

scientific article published on 10 January 2014

Poly(ethylene glycol)s generate complement activation products in human serum through increased alternative pathway turnover and a MASP-2-dependent process.

scientific article

Poly-(amidoamine) dendrimers with a precisely core positioned sulforhodamine B molecule for comparative biological tracing and profiling

scientific article published on 29 December 2016

Polycation-mediated integrated cell death processes.

scientific article

Polyethylenimine architecture-dependent metabolic imprints and perturbation of cellular redox homeostasis.

scientific article

Polyethylenimine-mediated impairment of mitochondrial membrane potential, respiration and membrane integrity: implications for nucleic acid delivery and gene therapy

scientific article published on 10 September 2011

Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective

scientific article published on 27 July 2012

Polymeric particulate technologies for oral drug delivery and targeting: a pathophysiological perspective.

scientific article published on 17 June 2012

Polyplex Evolution: Understanding Biology, Optimizing Performance

scientific article published on 5 March 2017

Prolonging the circulation time and modifying the body distribution of intravenously injected polystyrene nanospheres by prior intravenous administration of poloxamine-908. A `hepatic-blockade' event or manipulation of nanosphere surface in vivo? ⬇️

scientific article published on July 19, 1997

Publisher Correction: Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles

scientific article published on 01 March 2019

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

scientific article published on 01 August 2019

Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

scientific article published on 01 September 2019

Re-establishing the long circulatory behaviour of poloxamine-coated particles after repeated intravenous administration: applications in cancer drug delivery and imaging

scientific article published on 01 October 1999

Real-time evidence of surface modification at polystyrene lattices by poloxamine 908 in the presence of serum: in vivo conversion of macrophage-prone nanoparticles to stealth entities by poloxamine 908.

scientific article

Recent advances in cellular, sub-cellular and molecular targeting

scientific article published on 01 March 2000

Recent developments in polymeric nanoparticle engineering and their applications in experimental and clinical oncology.

scientific article published on November 2006

Reciprocity in the developmental regulation of aquaporins 1, 3 and 5 during pregnancy and lactation in the rat

scientific article

Recognition and clearance of methoxypoly(ethyleneglycol)2000-grafted liposomes by macrophages with enhanced phagocytic capacity. Implications in experimental and clinical oncology

scientific article published in June 2001

Recognition by macrophages and liver cells of opsonized phospholipid vesicles and phospholipid headgroups.

scientific article

Recognition of extremophilic archaeal viruses by eukaryotic cells: a promising nanoplatform from the third domain of life

scientific article published on 28 November 2016

Repeated intraperitoneal injections of liposomes containing phosphatidic acid and cardiolipin reduce amyloid-β levels in APP/PS1 transgenic mice.

scientific article published on 14 November 2014

Reprogramming the lymphocyte axis for advanced immunotherapy

scientific article published on 01 February 2019

Reshaping the future of nanopharmaceuticals: ad iudicium.

scientific article published on 12 October 2011

Revealing Dynamics of Accumulation of Systemically Injected Liposomes in the Skin by Intravital Microscopy

scientific article

Serum factors that regulate phagocytosis of liposomes by Kupffer cells

scientific article published on 01 May 1993

Serum opsonins and phagocytosis of saturated and unsaturated phospholipid liposomes

scientific article

Serum-mediated recognition of liposomes by phagocytic cells of the reticuloendothelial system - The concept of tissue specificity

scientific article published on 01 June 1998

Single-walled carbon nanotube surface control of complement recognition and activation.

scientific article

Soluble and immobilized graphene oxide activates complement system differently dependent on surface oxidation state

scientific article published on 19 November 2015

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties ⬇️

scientific article published on November 1, 2003

Structural profiling and biological performance of phospholipid-hyaluronan functionalized single-walled carbon nanotubes

scientific article published on 10 June 2013

Subcutaneous and intravenous delivery of diagnostic agents to the lymphatic system: applications in lymphoscintigraphy and indirect lymphography

scientific article published on 01 April 1999

Surface engineered nanospheres with enhanced drainage into lymphatics and uptake by macrophages of the regional lymph nodes

scientific article published on 01 May 1994

Surfactant-mediated complement activation in beagle dogs.

scientific article published on 2 June 2013

Synthetic polymers in 21st century therapeutics: the way forward

scientific article published on 01 February 2003

T cells expressing VHH-directed oligoclonal chimeric HER2 antigen receptors: towards tumor-directed oligoclonal T cell therapy.

scientific article

Targeting Biological Barriers: Turning a Wall into a Therapeutic Springboard

scientific article

The Interplay Between Blood Proteins, Complement, and Macrophages on Nanomedicine Performance and Responses

scientific article published on 02 April 2019

The effect of block co-polymers on the uptake of model polystyrene microspheres by Kupffer cells--in vitro and in vivo studies

scientific article published on 01 August 1991

The effect of methoxy-PEG chain length and molecular architecture on lymph node targeting of immuno-PEG liposomes

scientific article published in January 2006

The polyoxyethylene/polyoxypropylene block co-polymer poloxamer-407 selectively redirects intravenously injected microspheres to sinusoidal endothelial cells of rabbit bone marrow

scientific article published on 01 June 1992

The possible "proton sponge " effect of polyethylenimine (PEI) does not include change in lysosomal pH.

scientific article published on 2 October 2012

Therapeutic synthetic polymers: a game of Russian roulette?

scientific article

Tissue specific opsonins for phagocytic cells and their different affinity for cholesterol-rich liposomes

scientific article published on 01 June 1988

Total Internal Reflection Fluorescence (TIRF) Microscopy for Real-Time Imaging of Nanoparticle-Cell Plasma Membrane Interaction ⬇️

scientific article published on January 1, 2012

Transformation of structurally diverse steroidal analogues by the fungus Corynespora cassiicola CBS 161.60 results in generation of 8β-monohydroxylated metabolites with evidence in favour of 8β-hydroxylation through inverted binding in the 9α-hydrox

scientific article

Translational gaps in animal models of human infusion reactions to nanomedicines

scientific article published on 23 May 2018

Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness

scientific article

Tunable 3D and 2D polystyrene nanoparticle assemblies using surface wettability, low volume fraction and surfactant effects

scientific article published on 09 December 2008

Tuning the Engines of Nanomedicine

scientific article published on 07 February 2020

Paulina is supported by:

About Paulina

Help