List of works - Kristian Unger

A Critical Evaluation of the PAXgene Tissue Fixation System: Morphology, Immunohistochemistry, Molecular Biology, and Proteomics

scientific article published in July 2016

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

scientific article published on September 2017

Analysis of chromosomal aberrations in murine HCC.

scientific article

Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells

scientific article

Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC.

scientific article published on 14 April 2008

Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma.

scientific article

Association of Radiation-Induced Genes with Noncancer Chronic Diseases in Mayak Workers Occupationally Exposed to Prolonged Radiation

article

CFAssay: statistical analysis of the colony formation assay

scientific article published on 4 November 2015

CLIP2 as radiation biomarker in papillary thyroid carcinoma.

scientific article published on 6 October 2014

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

scientific article

Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients.

scientific article published on 28 December 2013

Chromosomal changes characterize head and neck cancer with poor prognosis

scientific article published on 23 September 2008

Circulating microRNAs as prognostic therapy biomarkers in head and neck cancer patients

scientific article

DNA copy number alterations in radiation-induced thyroid cancer.

scientific article published on May 2011

Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair

scientific article

Differential Response and Priming Dose Effect on the Proteome of Human Fibroblast and Stem Cells Induced by Exposure to Low Doses of Ionizing Radiation.

scientific article published on 02 March 2016

Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.

scientific article published on 8 May 2015

Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development

scientific article published on 27 July 2016

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma

scientific article

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

scientific article published on 24 January 2018

Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer

scientific article published on 25 September 2017

Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiation

scientific article

Gene amplification of atypical PKC-binding PARD3 in radiation-transformed neoplastic retinal pigment epithelial cell lines

scientific article published on May 2004

Gene expression analysis in Mayak workers with prolonged occupational radiation exposure.

scientific article published in June 2014

Gene signature of the post-Chernobyl papillary thyroid cancer

scientific article published on 26 January 2016

Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance

scientific article published on 17 November 2016

Genomic copy number analysis of Chernobyl papillary thyroid carcinoma in the Ukrainian-American Cohort

scientific article

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.

scientific article

Heterogeneity in the distribution of RET/PTC rearrangements within individual post-Chernobyl papillary thyroid carcinomas

scientific article published on September 2004

High resolution array-CGH analysis of single cells

scientific article

Independent validation of candidate genes identified after a whole genome screening on Mayak workers exposed to prolonged occupational radiation

scientific article published on 30 July 2014

Integrating research on thyroid cancer after Chernobyl--the Chernobyl Tissue Bank

scientific article

Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment

scientific article published on 11 October 2016

Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cells

scientific article published on 2 September 2015

Integrative radiation systems biology.

scientific article published on 11 January 2014

Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis.

scientific article

In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells

scientific article published on 20 March 2017

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

scientific article

Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk

scientific article

Matching of array CGH and gene expression microarray features for the purpose of integrative genomic analyses.

scientific article

Mechanisms of the induction of apoptosis mediated by radiation-induced cytokine release.

scientific article

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

scientific article

MicroRNA profiling with correlation to gene expression revealed the oncogenic miR-17-92 cluster to be up-regulated in osteosarcoma

scientific article

MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma

scientific article published on 18 December 2015

Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma Physiology Determine Therapy Response to Sorafenib

scientific article published on 20 May 2015

Molecular rearrangements in papillary thyroid carcinomas.

scientific article published on December 2009

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

scientific article

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

scientific article

Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.

scientific article

Novel gene rearrangements in transformed breast cells identified by high-resolution breakpoint analysis of chromosomal aberrations

scientific article

Posterior subcapsular cataracts are a late effect after acute exposure to 0.5 Gy ionizing radiation in mice

scientific article published on 19 January 2021

RET/PTC rearrangement occurring in primary peritoneal carcinoma.

scientific article

RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.

scientific article published on 4 April 2006

RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation

scientific article published on 22 August 2013

S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI imaging.

scientific article

Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer

scientific article

Taxane-mediated radiosensitization derives from chromosomal missegregation on tripolar mitotic spindles orchestrated by AURKA and TPX2.

scientific article published on 4 September 2017

The chernobyl tissue bank - a repository for biomaterial and data used in integrative and systems biology modeling the human response to radiation.

scientific article

Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis

scientific article published on 12 June 2015

Transcriptome network of the papillary thyroid carcinoma radiation marker CLIP2

scientific article published on 29 July 2020

Transcriptomic analyses of the radiation response in head and neck squamous cell carcinoma subclones with different radiation sensitivity: time-course gene expression profiles and gene association networks.

scientific article

List of works by Kristian Unger

A Critical Evaluation of the PAXgene Tissue Fixation System: Morphology, Immunohistochemistry, Molecular Biology, and Proteomics

A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development

Analysis of chromosomal aberrations in murine HCC.

Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells

Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC.

Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma.

Association of Radiation-Induced Genes with Noncancer Chronic Diseases in Mayak Workers Occupationally Exposed to Prolonged Radiation

CFAssay: statistical analysis of the colony formation assay

CLIP2 as radiation biomarker in papillary thyroid carcinoma.

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients.

Chromosomal changes characterize head and neck cancer with poor prognosis

Circulating microRNAs as prognostic therapy biomarkers in head and neck cancer patients

DNA copy number alterations in radiation-induced thyroid cancer.

Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair

Differential Response and Priming Dose Effect on the Proteome of Human Fibroblast and Stem Cells Induced by Exposure to Low Doses of Ionizing Radiation.

Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.

Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

Expression of miRNA-26b-5p and its target TRPS1 is associated with radiation exposure in post-Chernobyl breast cancer

Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiation

Gene amplification of atypical PKC-binding PARD3 in radiation-transformed neoplastic retinal pigment epithelial cell lines

Gene expression analysis in Mayak workers with prolonged occupational radiation exposure.

Gene signature of the post-Chernobyl papillary thyroid cancer

Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance

Genomic copy number analysis of Chernobyl papillary thyroid carcinoma in the Ukrainian-American Cohort

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.

Heterogeneity in the distribution of RET/PTC rearrangements within individual post-Chernobyl papillary thyroid carcinomas

High resolution array-CGH analysis of single cells

Independent validation of candidate genes identified after a whole genome screening on Mayak workers exposed to prolonged occupational radiation

Integrating research on thyroid cancer after Chernobyl--the Chernobyl Tissue Bank

Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment

Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cells

Integrative radiation systems biology.

Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis.

In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

Lifetime study in mice after acute low-dose ionizing radiation: a multifactorial study with special focus on cataract risk

Matching of array CGH and gene expression microarray features for the purpose of integrative genomic analyses.

Mechanisms of the induction of apoptosis mediated by radiation-induced cytokine release.

Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

MicroRNA profiling with correlation to gene expression revealed the oncogenic miR-17-92 cluster to be up-regulated in osteosarcoma

MicroRNA-Target Network Inference and Local Network Enrichment Analysis Identify Two microRNA Clusters with Distinct Functions in Head and Neck Squamous Cell Carcinoma

Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma Physiology Determine Therapy Response to Sorafenib

Molecular rearrangements in papillary thyroid carcinomas.

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

Novel candidate genes of thyroid tumourigenesis identified in Trk-T1 transgenic mice.

Novel gene rearrangements in transformed breast cells identified by high-resolution breakpoint analysis of chromosomal aberrations

Posterior subcapsular cataracts are a late effect after acute exposure to 0.5 Gy ionizing radiation in mice

RET/PTC rearrangement occurring in primary peritoneal carcinoma.

RET/papillary thyroid cancer rearrangement in nonneoplastic thyrocytes: follicular cells of Hashimoto's thyroiditis share low-level recombination events with a subset of papillary carcinoma.

RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation

S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI imaging.

Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer

Taxane-mediated radiosensitization derives from chromosomal missegregation on tripolar mitotic spindles orchestrated by AURKA and TPX2.

The chernobyl tissue bank - a repository for biomaterial and data used in integrative and systems biology modeling the human response to radiation.

Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis

Transcriptome network of the papillary thyroid carcinoma radiation marker CLIP2

Transcriptomic analyses of the radiation response in head and neck squamous cell carcinoma subclones with different radiation sensitivity: time-course gene expression profiles and gene association networks.