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List of works by Gennaro Ciliberto

A Bipartite Activation Domain Is Responsible for the Activity of Transcription Factor HNF1/LFB1 in Cells of Hepatic and Nonhepatic Origin

scientific article published on 01 April 1993

A TLR9 agonist enhances therapeutic effects of telomerase genetic vaccine.

scientific article published on 21 March 2010

A Xenopus multifinger protein, Xfin, is expressed in specialized cell types and is localized in the cytoplasm

scientific article published on December 1991

A fast and sensitive colorimetric assay for IL-6 in hepatoma cells based on the production of a secreted form of alkaline phosphatase (SEAP).

scientific article published on March 1994

A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand

scientific article published in August 2005

A general method to select for M13 clones carrying base pair substitution mutants constructed in vitro

scientific article

A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study

scientific article

A novel chimpanzee serotype-based adenoviral vector as delivery tool for cancer vaccines

scientific article published on 20 January 2009

A novel method for site-directed mutagenesis: its application to an eukaryotic tRNAPro gene promoter

scientific article

A novel minigene scaffold for therapeutic cancer vaccines

scientific article

A novel mouse model for evaluation and prediction of HLA-A2-restricted CEA cancer vaccine responses

scientific article

A novel multi-drug metronomic chemotherapy significantly delays tumor growth in mice

scientific article published on 24 February 2016

A paradigm shift for erythropoietin: no longer a specialized growth factor, but rather an all-purpose tissue-protective agent

scientific article published in July 2004

A prokaryotic tRNATyr gene, inactive in Xenopus laevis oocytes, is activated by recombination with an eukaryotic tRNAPro gene ⬇️

scientific article published on January 1, 1982

A retrospective multicentric observational study of trastuzumab emtansine in HER2 positive metastatic breast cancer: a real-world experience

scientific article published on 25 May 2017

A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies

scientific article

A study on the structural features of SELK, an over-expressed protein in hepatocellular carcinoma, by molecular dynamics simulations in a lipid-water system

scientific article published on 15 August 2016

A therapeutic cancer vaccine targeting carcinoembryonic antigen in intestinal carcinomas

scientific article

A vaccine targeting telomerase enhances survival of dogs affected by B-cell lymphoma.

scientific article published on 8 June 2010

Abscopal effects of radiotherapy on advanced melanoma patients who progressed after ipilimumab immunotherapy.

scientific article

Accreditation for excellence of cancer research institutes: recommendations from the Italian Network of Comprehensive Cancer Centers

scientific article

Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies.

scientific article published on 27 July 2013

Activation of the ErbB3-AKT axis promotes melanoma cell survival and proliferation in response to RAF/MEK inhibition.

scientific article published on 6 May 2014

Acute rejection after heart transplantation: Noninvasive echocardiographic evaluation

scientific article published on 01 April 1994

Alliance Against Cancer, the network of Italian cancer centers bridging research and care

scientific article

Alu sequences transcription in X. laevis oocytes: nuclear-cytoplasmic partitioning and evidence for 3' end processing reactions

scientific article

An adenovirus type 5 (Ad5) amplicon-based packaging cell line for production of high-capacity helper-independent deltaE1-E2-E3-E4 Ad5 vectors

scientific article

An efficient T-cell epitope discovery strategy using in silico prediction and the iTopia assay platform

scientific article published on November 2012

An improved helper-dependent adenoviral vector allows persistent gene expression after intramuscular delivery and overcomes preexisting immunity to adenovirus

scientific article published on 15 May 2001

An interaction network approach to study the correlation between endocrine disrupting chemicals and breast cancer.

scientific article

An oral TLR7 agonist is a potent adjuvant of DNA vaccination in transgenic mouse tumor models

scientific article

Analysis of human/mouse interleukin-6 hybrid proteins: both amino and carboxy termini of human interleukin-6 are required forin vitro receptor binding

article

Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression. ⬇️

scientific article published on 14 August 2017

Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assay

scientific article published in April 2004

Anti-EphA2 Antibodies with Distinct In Vitro Properties Have Equal In Vivo Efficacy in Pancreatic Cancer

scientific article

Anti-Inflammatory Effects of a Methanol Extract from the Marine Sponge Geodia cydonium on the Human Breast Cancer MCF-7 Cell Line

scientific article

Anti-inflammatory actions of an N-terminal peptide from human lipocortin 1.

scientific article

Antiapoptotic small interfering RNA as potent adjuvant of DNA vaccination in a mouse mammary tumor model.

scientific article published in June 2009

Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients

scientific article published on 11 September 2018

Aorto-atrial fistula through the septum in recurrent aortic dissection

scientific article published on 01 September 2001

Assessing a novel immuno-oncology-based combination therapy: Ipilimumab plus electrochemotherapy

scientific article published on 22 May 2015

AurkA inhibitors enhance the effects of B-RAF and MEK inhibitors in melanoma treatment

scientific article

AurkA inhibitors enhance the effects of B-RAF and MEK inhibitors in melanoma treatment

Axitinib after Sunitinib in Metastatic Renal Cancer: Preliminary Results from Italian "Real-World" SAX Study.

scientific article published on 28 September 2016

B4GALT1 Is a New Candidate to Maintain the Stemness of Lung Cancer Stem Cells

scientific article published on 09 November 2019

BMI and breast cancer prognosis benefit: mammography screening reveals differences between normal weight and overweight women

scientific article published on 29 November 2014

Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells.

scientific article published on 07 August 2017

Blocking signaling through the Gp130 receptor chain by interleukin-6 and oncostatin M inhibits PC-3 cell growth and sensitizes the tumor cells to etoposide and cisplatin-mediated cytotoxicity

scientific article published on January 1999

Body mass index in HER2-negative metastatic breast cancer treated with first-line paclitaxel and bevacizumab.

scientific article published on 16 January 2018

Body weight and risk of molecular breast cancer subtypes among postmenopausal Mediterranean women.

scientific article

Breast cancer screening, body mass index and prognosis benefit

scientific article published in September 2014

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy

scientific journal article

CD4+CD25+ regulatory T-cell-inactivation in combination with adenovirus vaccines enhances T-cell responses and protects mice from tumor challenge.

scientific article published on 20 October 2006

CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR.

scientific article published on 26 February 2016

Cancer Stem Cells and the Slow Cycling Phenotype: How to Cut the Gordian Knot Driving Resistance to Therapy in Melanoma

scientific article published on 13 November 2020

Cancer mortality trends between 1988 and 2009 in the metropolitan area of Naples and Caserta, Southern Italy: Results from a joinpoint regression analysis

scientific article published on 09 September 2013

Cancer vaccination by electro-gene-transfer.

scientific article

Carnitines slow down tumor development of colon cancer in the DMH-chemical carcinogenesis mouse model

article

Cell cycle regulation and induction of apoptosis by IL-6 variants on the multiple myeloma cell line XG-1.

scientific article published on January 1999

Cell-specific expression of a transfected human alpha 1-antitrypsin gene

scientific article published in June 1985

Characterization of mononuclear-phagocyte terminal maturation by mRNA phenotyping using a set of cloned cDNA probes

scientific article published on 01 November 1989

Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

scientific article

Circulating MMP11 and specific antibody immune response in breast and prostate cancer patients

scientific article published on 24 February 2014

Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study

scientific article published in 2022

Coadministration of telomerase genetic vaccine and a novel TLR9 agonist in nonhuman primates

scientific article

Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer

scientific article published on 04 September 2018

Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver.

scientific article

Color Doppler echocardiographic assessment of atrial septal defect size: correlation with surgical measurements

scientific article published in September 1991

Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma.

scientific article published on 7 July 2015

Combination of inositol and alpha lipoic acid in metabolic syndrome-affected women: a randomized placebo-controlled trial

scientific article published on 28 August 2013

Combination therapy with anti-ErbB3 monoclonal antibodies and EGFR TKIs potently inhibits non-small cell lung cancer

scientific article published on August 2013

Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

scientific article published on 23 April 2019

Combinatorial immunotherapy strategies for hepatocellular carcinoma

scientific article published on 3 February 2016

Combining doxorubicin with a phenolic extract from flaxseed oil: Evaluation of the effect on two breast cancer cell lines

scientific article published on 2 January 2017

Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase III

article

Comparative effects of nifedipine, verapamil, isosorbide dinitrate and propranolol on exercise-induced angina pectoris

scientific article published on July 1979

Comparative effects of nifedipine, verapamil, isosorbide dinitrate and propranolol on exercise-induced angina pectoris

scientific article published on 01 January 1980

Comparative expression pathway analysis of human and canine mammary tumors.

scientific article

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

scientific article published on January 1999

Construction of an rtTA2(s)-m2/tts(kid)-based transcription regulatory switch that displays no basal activity, good inducibility, and high responsiveness to doxycycline in mice and non-human primates

scientific article published on February 2003

Coronary artery disease after heart transplantation: non-invasive evaluation with exercise thallium scintigraphy

scientific article published on 01 February 1993

Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

scientific article published on 04 July 2019

Correction: Metabolic syndrome, endocrine disruptors and prostate cancer associations: biochemical and pathophysiological evidences.

scientific article published on 22 September 2017

Corrigendum: Pazopanib in Metastatic Renal Cancer: A "Real-World" Experience at National Cancer Institute "Fondazione G. Pascale"

scientific article published on 5 December 2016

Critical stenoses of the common trunk of the left coronary artery

scientific article published on May 1978

CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions

scientific article published on 09 August 2019

DNA and Adenoviral Vectors Encoding Carcinoembryonic Antigen Fused to Immunoenhancing Sequences Augment Antigen-Specific Immune Response and Confer Tumor Protection

article

DNA sequence of a pseudogene for human C-reactive protein.

scientific article

Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells permits ErbB3 upregulation and increased growth

scientific article

Decreased expression of autophagic beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts.

scientific article published on July 2013

Deducing the functional characteristics of the human selenoprotein SELK from the structural properties of its intrinsically disordered C-terminal domain

scientific article published on 6 January 2016

Deep sequencing and pathway-focused analysis revealed multigene oncodriver signatures predicting survival outcomes in advanced colorectal cancer

scientific article published on 22 July 2018

Defective development of pristane-oil-induced plasmacytomas in interleukin-6-deficient BALB/c mice.

scientific article published on September 1997

Definition of a Composite Binding Site for gp130 in Human Interleukin-6

scientific article published in Journal of Biological Chemistry

Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation

scientific article published in April 2004

Development of progressive kidney damage and myeloma kidney in interleukin-6 transgenic mice

article

Differential Response of Two Human Breast Cancer Cell Lines to the Phenolic Extract from Flaxseed Oil.

scientific article published on 08 March 2016

Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti-HER2 agents in the real world setting

scientific article published on 07 August 2019

Dual control of C-reactive protein gene expression by interleukin-1 and interleukin-6.

scientific article published on December 1989

EMT markers in lung adenocarcinoma pleural effusion spheroid cells.

scientific article published in August 2013

Effect of adenosylhomocysteine and other analog thioethers on a prokaryotic tRNA (guanine-7)-methyltransferase

scientific article published in November 1982

Effects of IL-6 Variants in Multiple Myeloma: Growth Inhibition and Induction of Apoptosis in Primary Cells

scientific article published on 01 December 2002

Effects of the association of Ca-antagonists with nitroderivatives or betablocking drugs in effort angina pectoris (author's transl)

scientific article

Efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg.

scientific article published on 6 May 2014

Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA

scientific article

Electro‐gene‐transfer as a new tool for cancer immunotherapy in animals ⬇️

scientific article published on October 25, 2012

Elevated Levels of Interleukin-6 in Unstable Angina

scientific article published on 01 September 1996

Elevation of IL-6 in transgenic mice results in increased levels of the 90 kDa heat shock protein (hsp90) and the production of anti-hsp90 antibodies

scientific article published in June 1998

Emerging cancer vaccines: the promise of genetic vectors.

scientific article published on 22 September 2011

Engineering human interleukin-6 to obtain variants with strongly enhanced bioactivity.

scientific article published on June 1996

Enhanced Inflammatory Response to Coronary Angioplasty in Patients With Severe Unstable Angina

article

Epigenetic changes induced by green tea catechins are associated with prostate cancer.

scientific article published on 18 December 2017

ErbB2 genetic cancer vaccine in nonhuman primates: relevance of single nucleotide polymorphisms

scientific article published in March 2009

ErbB3 Phosphorylation as Central Event in Adaptive Resistance to Targeted Therapy in Metastatic Melanoma: Early Detection in CTCs during Therapy and Insights into Regulation by Autocrine Neuregulin

scientific article published on 25 September 2019

ErbB3 plays a key role in the early phase of establishment of resistance to BRAF and/or MEK inhibitors

scientific article

Eribulin in Triple Negative Metastatic Breast Cancer: Critic Interpretation of Current Evidence and Projection for Future Scenarios

scientific article published on 12 October 2019

Erratum to: Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanoma

scholarly article published in Cancer Immunology, Immunotherapy

Erratum: Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells permits ErbB3 upregulation and increased growth

scientific article published on 01 March 2016

Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy

scientific article published on 5 February 2018

Expression of the murine interleukin 6 receptor in hepatoma cells: the intracytoplasmic domain is not required for interleukin 6 signal transduction

scientific article published on March 1, 1992

Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice

scientific article published on February 1997

Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition.

scientific article published on 22 August 2016

Formation of the 3' end on U snRNAs requires at least three sequence elements.

scientific article

Functional assay of tRNA molecules transcribed from a purified gene.

scientific article published on November 1982

Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016. ⬇️

scientific article published on 16 November 2017

Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.

scientific article

Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012".

scientific article published on 3 June 2013

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge", Napoli, December 5th-8th 2013.

scientific article

Future perspectives in melanoma research: meeting report from the "Melanoma Bridge": Napoli, December 3rd-6th 2014.

scientific article published on 30 November 2015

Gene Electrotransfer Results in a High-Level Transduction of Rat Skeletal Muscle and Corrects Anemia of Renal Failure

article

Gene electro-transfer improves transduction by modifying the fate of intramuscular DNA.

scientific article published in April 2003

Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates

scientific article

Gene therapy progress and prospects: transcription regulatory systems.

scientific article published on April 2004

Generation of interleukin-6 receptor antagonists by molecular-modeling guided mutagenesis of residues important for gp130 activation

scientific article

Genetic and Functional Analysis of Polymorphisms in the Human Dopamine Receptor and Transporter Genes in Small Cell Lung Cancer

scientific article

Genetic cancer vaccines: current status and perspectives.

scientific article published on 12 May 2012

Genetic vaccines against Ep-CAM break tolerance to self in a limited subset of subjects: initial identification of predictive biomarkers

scientific article published in May 2006

Global changes in interleukin-6–dependent gene expression patterns in mouse livers after partial hepatectomy

article

Growth delay of human bladder cancer cells by Prostate Stem Cell Antigen downregulation is associated with activation of immune signaling pathways

scientific article

HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome.

scientific article

Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy

scientific article published in October 2007

Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice

scientific article published on August 1998

High circulating levels of biologically inactive IL-6/SIL-6 receptor complexes in systemic juvenile idiopathic arthritis: evidence for serum factors interfering with the binding to gp130

article

High yield expression and purification of human endothelin-1.

scientific article

High-dose dipyridamole echocardiography test in coronary artery disease after heart transplantation

scientific article published in January 1993

Highly durable response to capecitabine in patient with metastatic estrogen receptor positive breast cancer: A case report

scientific article published on 01 September 2019

Homeodomain-interacting protein kinase2 in human idiopathic pulmonary fibrosis

scientific article

Homeostasis model assessment to detect insulin resistance and identify patients at high risk of breast cancer development: National Cancer Institute of Naples experience

scientific article published on 14 March 2013

Human MiR-544a Modulates SELK Expression in Hepatocarcinoma Cell Lines.

scientific article

Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells.

scientific article

Human interleukin-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells

scientific article published on 01 June 1996

Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity

scientific article published on 29 February 2016

Hyaluronidase increases electrogene transfer efficiency in skeletal muscle

scientific article published in February 2002

IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients

scientific article published on 7 December 2016

IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage.

scientific article published on December 1995

IL-6 is an in vitro and in vivo autocrine growth factor for middle T antigen-transformed endothelial cells.

scientific article published on September 1996

IL-6 is required for airway mucus production induced by inhaled fungal allergens

scientific article

IL-6 knock-out mice exhibit resistance to splanchnic artery occlusion shock.

scientific article

IL-6 mediates the effects of IL-1 or TNF, but not PTHrP or 1,25(OH)2D3, on osteoclast-like cell formation in normal human bone marrow cultures

scientific article

IMPAIRED STAT3 ACTIVATION FOLLOWING LOCALIZED INFLAMMATORY STIMULUS IN IL-6-DEFICIENT MICE

scientific article published on 01 January 1998

Identification and Validation of HCC-specific Gene Transcriptional Signature for Tumor Antigen Discovery

scientific article published on 08 July 2016

Identification of sequences responsible for acute-phase induction of human C-reactive protein.

scientific article

Identifying a panel of genes/proteins/miRNAs modulated by arsenicals in bladder, prostate, kidney cancers

scientific article published in Scientific Reports

Immune responses against tetracycline-dependent transactivators affect long-term expression of mouse erythropoietin delivered by a helper-dependent adenoviral vector

scientific article

Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates

Immunogenicity and therapeutic efficacy of a dual-component genetic cancer vaccine cotargeting carcinoembryonic antigen and HER2/neu in preclinical models.

scientific article published on 21 December 2013

Immunological and biological changes during ipilimumab treatment and their potential correlation with clinical response and survival in patients with advanced melanoma

article

Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015

scientific article published on 20 September 2016

Immunoscore: a new possible approach for melanoma classification

article by Mariaelena Capone et al published 2014 in Journal for Immunotherapy of Cancer

Immunotherapy in HER2-positive breast cancer: state of the art and future perspectives

scientific article published on 29 October 2019

Impact of BMI on HER2+ metastatic breast cancer patients treated with pertuzumab and/or trastuzumab emtansine. Real-world evidence

scientific article published on 15 January 2020

In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma

scientific article published on 12 March 2020

In Vivo Neutralization of Human IL-6 (hIL-6) Achieved by Immunization of hIL-6-Transgenic Mice with a hIL-6 Receptor Antagonist

scientific article published on 01 April 2001

In vitro binding of ciliary neurotrophic factor to its receptors: evidence for the formation of an IL-6-type hexameric complex

scientific article published on December 1995

In vivo DNA gene electro-transfer: a systematic analysis of different electrical parameters

scientific article published in November 2005

In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway

scientific article published in August 1998

Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice

article

Inducible formation of liver tumors in transgenic mice.

scientific article published in January 1993

Induction of interleukin-6 (IL-6) autoantibodies through vaccination with an engineered IL-6 receptor antagonist

scientific article published on 01 October 1997

Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma

scientific article published on 17 December 2018

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

scientific article

Inhibition of eukaryotic tRNA transcription by potential Z-DNA sequences.

scientific article

Interleukin 18: friend or foe in cancer

scientific article published on 08 October 2013

Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death

scientific article published on September 1996

Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor alpha mutated in the predicted gp130-binding interface

scientific article published on May 1995

Interleukin-6 involvement in antidepressant action of Hypericum perforatum

scientific article published in July 2001

Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.

scientific article

Interleukin-6-induced STAT3 and AP-1 amplify hepatocyte nuclear factor 1-mediated transactivation of hepatic genes, an adaptive response to liver injury

scientific article published on January 2001

Internal deletions in human interleukin-6: structure-function analysis.

scientific article published in August 1991

Internal deletions of amino acids 29-42 of human interleukin-6 (IL-6) differentially affect bioactivity and folding.

scientific article published in August 1991

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

scientific article published in The Lancet

Intrablastocyst injection with human CD34+/CD133+ cells increase survival of immunocompetent fumarylacetoacetate hydrolase knockout mice

scientific article published in October 2012

Intratumor RNA interference of cell cycle genes slows down tumor progression

scientific article published on 10 March 2011

Involvement of the Arg179 in the active site of human IL-6

scientific article published on 01 February 1993

Isolation and characterization of a tRNA(guanine-7-)-methyltransferase from Salmonella typhimurium

scientific article published in January 1983

Isolation of Fully Human Antagonistic RON Antibodies Showing Efficient Block of Downstream Signaling and Cell Migration.

scientific article

Kinesin spindle protein SiRNA slows tumor progression

scientific article published on January 2013

Left ventricular performance in chronic mitral regurgitation: temporal response to valve repair and prognostic value of early postoperative echocardiographic parameters.

scientific article

Leptin receptor-mediated regulation of cholinergic neurotransmitter phenotype in cells of central nervous system origin

scientific article published in May 2000

Light at the end of the canaliculus. First Instituto Ricerche di Biologia Molecolare Symposium on Gene Expression During Liver Differentiation and Disease, Sorrento, Italy, June 2-6, 1991.

scientific article published in November 1991

Liquid dynamic medicine and N-of-1 clinical trials: a change of perspective in oncology research.

scientific article published on 13 September 2017

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice

scientific article published in November 1996

Liver-specific alpha 2 interferon gene expression results in protection from induced hepatitis

scientific article

Long-term and tight control of gene expression in mouse skeletal muscle by a new hybrid human transcription factor

scientific article

Look for methods, not conclusions

scientific article published on 05 December 2019

Loss of heterozygosity of imprinted genes in SV40 t/T antigen-induced hepatocellular carcinomas

scientific article published on August 17, 1995

Low glycemic index diet, exercise and vitamin D to reduce breast cancer recurrence (DEDiCa): design of a clinical trial

scientific article

Lung cancer stem cell lose their stemness default state after exposure to microgravity

scientific article published on 7 September 2014

MISIPI study: Melanoma ImmunoScore evaluation in patients treated with IPIlimumab.

scientific article published on 6 May 2014

MMP11: a novel target antigen for cancer immunotherapy

scientific article published on 9 June 2009

Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs

scientific article published on 13 July 2010

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Metabolic features of cancer stem cells: the emerging role of lipid metabolism.

scientific article published on 15 February 2018

Metabolic syndrome and the risk of urothelial carcinoma of the bladder: a case-control study

scientific article published on 16 October 2015

Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype

scientific article

MicroRNA-driven deregulation of cytokine expression helps development of drug resistance in metastatic melanoma.

scientific article

MicroRNAs in melanoma development and resistance to target therapy

scientific article published on 19 January 2017

Modulation of the immune response induced by gene electrotransfer of a hepatitis C virus DNA vaccine in nonhuman primates

scientific article published on November 2006

Monoclonal antibody-induced ErbB3 receptor internalization and degradation inhibits growth and migration of human melanoma cells.

scientific article

Monovalent phage display of human interleukin (hIL)-6: selection of superbinder variants from a complex molecular repertoire in the hIL-6 D-helix.

scientific article published on December 1995

Mortality trend for liver cancer in a hyperendemic area of hepatitis C virus infection in southern Italy: join-point analysis and comparison with European and Italian data

scientific article published in February 2014

Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer

scientific article published on 08 September 2020

Mutations in Box B of the promoter of a eucaryotic tRNAPro gene affect rate of transcription, processing, and stability of the transcripts

scientific article published in January 1984

Mutations in the KEAP1-NFE2L2 Pathway Define a Molecular Subset of Rapidly Progressing Lung Adenocarcinoma

scientific article published on 16 July 2019

Neoadjuvant Chemotherapy In Triple-Negative Breast Cancer: A Multicentric Retrospective Observational Study In Real-Life Setting.

scientific article published on 15 July 2017

Neoadjuvant Endocrine Therapy in Breast Cancer: Current Knowledge and Future Perspectives ⬇️

scientific article published on 16 May 2020

Neurotrophin system activation in pleural effusions.

scientific article published in August 2010

New developments in cancer vaccines

scientific article published in October 2013

Normal hepatocytes or foie gras?

scientific article published on 01 January 1996

Novel anti-ErbB3 monoclonal antibodies show therapeutic efficacy in xenografted and spontaneous mouse tumors

scientific article

Novel metronomic chemotherapy and cancer vaccine combinatorial strategy for hepatocellular carcinoma in a mouse model

scientific article

Observational Multicenter Study on the Prognostic Relevance of Coagulation Activation in Risk Assessment and Stratification in Locally Advanced Breast Cancer. Outline of the ARIAS Trial

scientific article published on 01 April 2020

Observational study of coagulation activation in early breast cancer: development of a prognostic model based on data from the real world setting.

scientific article

On the connections between cancer stem cells and EMT.

scientific article published on 16 November 2012

Oncostatin M binds directly to gp130 and behaves as interleukin-6 antagonist on a cell line expressing gp130 but lacking functional oncostatin M receptors

scientific article published on April 1994

Overexpression of interleukin-6 in the central nervous system of transgenic mice increases central but not systemic proinflammatory cytokine production

scientific article published in November 1996

Palbociclib plus endocrine therapy in HER2 negative, hormonal receptor-positive, advanced breast cancer: A real-world experience

scientific article published on 10 December 2018

Patented cancer vaccines: the promising leads

scientific article published on May 2010

Pazopanib in Metastatic Renal Cancer: A "Real-World" Experience at National Cancer Institute "Fondazione G. Pascale"

scientific article published on 31 August 2016

Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)

scientific article published on 21 July 2018

Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors ⬇️

scientific article published on March 8, 2013

Phenotype characterization of human melanoma cells resistant to dabrafenib

scientific article

Poly-specific neoantigen-targeted cancer vaccines delay patient derived tumor growth

scientific article published on 14 February 2019

Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma

scientific article published on 05 September 2019

Presence of a reduced opioid response in interleukin-6 knock out mice

scientific article published in May 1999

Preventive vaccination with telomerase controls tumor growth in genetically engineered and carcinogen-induced mouse models of cancer

scientific article published in December 2008

Processing of eukaryotic tRNA precursors: secondary structure of the precursor specific sequences affects the rate but not the accuracy of processing reactions.

scientific article published on July 1982

Prognostic relevance of DNA damage and repair biomarkers in elderly patients with hormone-receptor-positive breast cancer treated with neoadjuvant hormone therapy: evidence from the real-world setting

scientific article published on 18 August 2019

Prognostic value of contractile response during high-dose dipyridamole echocardiography test in heart transplant recipients

scientific article published in May 2003

Prolonged expression and effective readministration of erythropoietin delivered with a fully deleted adenoviral vector

scientific article published in April 2000

Promoter of a eukaryotic tRNAPro gene is composed of three noncontiguous regions.

scientific article

Purification of pseudouridylate synthetase I from Salmonella typhimurium ⬇️

scientific article published on December 1, 1978

Pyrvinium pamoate induces death of triple-negative breast cancer stem-like cells and reduces metastases through effects on lipid anabolism

scientific article published on 23 July 2020

Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer.

scientific article

Rational design of a receptor super-antagonist of human interleukin-6.

scientific article

Recombinant interleukin 6 regulates the transcriptional activation of a set of human acute phase genes.

scientific article published in September 1988

Regulated and Liver-Specific Tamarin Alpha Interferon Gene Delivery by a Helper-Dependent Adenoviral Vector

scientific article (publication date: June 2005)

Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector

scientific article published on December 2001

Relationship between the two components of the split promoter of eukaryotic tRNA genes.

scientific article

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

scientific article published on 25 September 2018

Resting echocardiography and quantitative dipyridamole technetium-99m sestamibi tomography in the identification of cardiac allograft vasculopathy and the prediction of long-term prognosis after heart transplantation.

scientific article

Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas.

scientific article

Risk Differences Between Prediabetes And Diabetes According To Breast Cancer Molecular Subtypes.

scientific article published on 31 August 2016

Risk of SARS-CoV-2 infection and disease in metastatic triple-negative breast cancer patients treated with immune checkpoint inhibitors

scientific article published on 03 June 2020

Role of DNA repair machinery and p53 in the testicular germ cell cancer: a review

scientific article

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

scientific article

Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma

scientific article

Role of Viral miRNAs and Epigenetic Modifications in Epstein-Barr Virus-Associated Gastric Carcinogenesis ⬇️

scientific article

Safety and efficacy of a genetic vaccine targeting Telomerase plus chemotherapy for the therapy of canine B-cell lymphoma

scientific article published on 7 November 2013

Selective cleavage of AAVS1 substrates by the adeno-associated virus type 2 rep68 protein is dependent on topological and sequence constraints

scientific article published on October 2000

Serum Cytokinome Profile Evaluation: A Tool to Define New Diagnostic and Prognostic Markers of Cancer Using Multiplexed Bead-Based Immunoassays

scientific article published on 06 December 2016

Serum miR-22 as potential non-invasive predictor of poor clinical outcome in newly diagnosed, uniformly treated patients with diffuse large B-cell lymphoma: an explorative pilot study.

scientific article published on 2 May 2018

Significance of pericardial effusion after heart transplantation

scientific article published on 01 August 1995

Single cell analysis to dissect molecular heterogeneity and disease evolution in metastatic melanoma

scientific article published on 31 October 2019

Single-step purification and structural characterization of human interleukin-6 produced in Escherichia coli from a T7 RNA polymerase expression vector.

scientific article published in June 1991

Site-specific integration in mammalian cells mediated by a new hybrid baculovirus-adeno-associated virus vector.

scientific article published on June 1998

Site-specific integration mediated by a hybrid adenovirus/adeno-associated virus vector.

scientific article

Soluble IL-6 receptor leads to a paracrine modulation of the IL-6-induced hepatic acute phase response in double transgenic mice.

scientific article

Spheres derived from lung adenocarcinoma pleural effusions: molecular characterization and tumor engraftment

scientific article (publication date: 2011)

Standardized Index of Shape (SIS): a quantitative DCE-MRI parameter to discriminate responders by non-responders after neoadjuvant therapy in LARC.

scientific article

Stearoyl-CoA desaturase-1 is a key factor for lung cancer-initiating cells

scientific article published on 5 December 2013

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

scientific article published on 19 June 2017

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

scientific article

Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators

scientific article

Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion

scientific article

Structural characterization of a biologically active human lipocortin 1 expressed in Escherichia coli

scientific article

Structure and expression of a Xenopus gene encoding an snRNP protein (U1 70K).

scientific article published on December 1988

Structure-function relationship of an Urokinase Receptor-derived peptide which inhibits the Formyl Peptide Receptor type 1 activity

scientific article published on 21 August 2019

Superior Immunologic and Therapeutic Efficacy of a Xenogeneic Genetic Cancer Vaccine Targeting Carcinoembryonic Human Antigen.

scientific article published in June 2015

Susceptibility to audiogenic seizure and neurotransmitter amino acid levels in different brain areas of IL-6-deficient mice

scientific article

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression.

scientific article published on 04 February 2016

Synergistic effect of gene-electro transfer and adjuvant cytokines in increasing the potency of hepatitis C virus genetic vaccination

scientific article published on September 2008

Synergistic induction of growth arrest and apoptosis of human myeloma cells by the IL-6 super-antagonist Sant7 and Dexamethasone

scientific article published on 01 March 2000

Synergistic stimulation of interleukin 6 release and gene expression by phorbol esters and interleukin 1 beta in rat cortical astrocytes: role of protein kinase C activation and blockade

scientific article published on May 1995

Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites.

scientific article published on December 1990

Synthesis and anti-hepatitis C virus activity of novel ethyl 1H-indole-3-carboxylates in vitro

scientific article published on 22 June 2010

Synthetic peptide vaccines: the quest to develop peptide vaccines for influenza, HIV and Alzheimer's disease

scientific article published in January 2009

Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion

scientific article published on 08 November 2019

Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells.

scientific article published on 8 December 2017

Tearing down the walls: FDA approves next generation sequencing (NGS) assays for actionable cancer genomic aberrations.

scientific article published on 5 March 2018

Tel-eVax: a genetic vaccine targeting telomerase for treatment of canine lymphoma

scientific article published on 11 December 2018

Telomerase and HER-2/neu as targets of genetic cancer vaccines in dogs.

scientific article

The Akt1/IL-6/STAT3 pathway regulates growth of lung tumor initiating cells

scientific article published on 13 October 2015

The Elapsed Time During a Virtual Reality Treatment for Stressful Procedures. A Pool Analysis on Breast Cancer Patients During Chemotherapy

The Experience of Oncology Healthcare Providers in the Central Italy during the COVID-19 Lockdown

scientific article published on 18 October 2020

The abscopal effect: efficacy of radiotherapy in patients on progression after treatment with ipilimumab 3 mg/kg

scientific article published on 7 November 2013

The additional facet of immunoscore: immunoprofiling as a possible predictive tool for cancer treatment

scientific article published on 3 March 2013

The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression

scientific article published on 24 April 2018

The clinical value of blunting of cyclic gray level variation for the detection of acute cardiac rejection: A two-dimensional, Doppler, and videodensitometric ultrasound study

scientific article published on 01 May 1996

The effort test in the diagnosis of typical stable effort angina (author's transl)

scientific article published on January 1977

The emerging role of cancer cell plasticity and cell-cycle quiescence in immune escape

scientific article published on 18 June 2020

The need for a network to establish and validate predictive biomarkers in cancer immunotherapy

scientific article published on 3 November 2017

The organization of clinical trials for oncology at IRCCS Istituto Nazionale Tumori "Fondazione G. Pascale" Napoli and the impact of the OECI accreditation process

scientific article

The perfect personalized cancer therapy: cancer vaccines against neoantigens.

scientific article published on 20 April 2018

The potential of BRAF-associated non-coding RNA as a therapeutic target in melanoma

scientific article published on 09 December 2018

The promise of anti-ErbB3 monoclonals as new cancer therapeutics ⬇️

scientific article published on August 1, 2012

The receptor super-antagonist Sant7

scientific article published on 01 May 1997

The two C/EBP isoforms, IL-6DBP/NF-IL6 and C/EBP delta/NF-IL6 beta, are induced by IL-6 to promote acute phase gene transcription via different mechanisms.

scientific article published on January 1993

The use of single locus and multilocus minisatellite probes to diagnose specific individuality.

scientific article published on January 1989

Therapeutic vaccination halts disease progression in BALB-neuT mice: the amplitude of elicited immune response is predictive of vaccine efficacy.

scientific article published on July 2008

Tight control of gene expression by a helper-dependent adenovirus vector carrying the rtTA2(s)-M2 tetracycline transactivator and repressor system.

scientific article published in November 2002

Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop

scientific article published on 22 May 2019

Transcription by RNA polymerase III.

scientific article published on January 1983

Transcription of multimeric tRNA genes.

scientific article

Transcription signals in embryonic Xenopus laevis U1 RNA genes

scientific article published on June 1985

Treatment of mammary carcinomas in HER-2 transgenic mice through combination of genetic vaccine and an agonist of Toll-like receptor 9.

scientific article published on 24 February 2009

Tricuspid regurgitation secondary to mitral valve disease: tricuspid annulus function as guide to tricuspid valve repair

scientific article published in August 2001

Triple negative breast cancer: looking for the missing link between biology and treatments

scientific article

TrkB is responsible for EMT transition in malignant pleural effusions derived cultures from adenocarcinoma of the lung

scientific article published on 2 May 2013

Tumor biobanks in translational medicine

scientific article published on 2 October 2012

Tumor genotype and immune microenvironment in POLE-ultramutated and MSI-hypermutated Endometrial Cancers: New candidates for checkpoint blockade immunotherapy?

scientific article published on 18 June 2016

Two distinct and independent sites on IL-6 trigger gp 130 dimer formation and signalling

scientific article published on May 1995

Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor.

scientific article

Usefulness of color Doppler in the diagnosis of ventricular septal rupture after myocardial infarction

scientific article published on 01 December 1990

Valor pronóstico de las medidas seriadas de la functión ventricular izquierda y del rendimiento en el ejercicio en la insuficiencia cardiaca crónica

scientific article published on 01 September 2006

Vectors encoding carcinoembryonic antigen fused to the B subunit of heat-labile enterotoxin elicit antigen-specific immune responses and antitumor effects.

scientific article published on 20 November 2007

Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway

scientific article published on 24 September 2015

WT1 CpG islands methylation in human lung cancer: a pilot study.

scientific article published on 20 August 2012

Which Variable of Stenosis Severity Best Describes the Significance of an Isolated Left Anterior Descending Coronary Artery Lesion?

scientific article published on 01 March 1998

Xenogene vaccination in the therapy of cancer

scientific article published on 15 July 2014

[Abnormal electrocardiographic changes induced by hypocalcemia secondary to extracorporeal circulation]

scientific article published on 01 April 1984

[Arrhythmias in patients with interatrial defect: pre- and post-operative study with dynamic ECG]

scientific article published on 01 January 1981

[Doppler echocardiography after heart transplantation]

scientific article published on 01 November 2000

[Dynamic ECG in patients surgically treated for interatrial defect: observations on 36 cases]

scientific article published on 01 January 1981

[Echocardiographic evaluation of mitral valve calcification]

scientific article published on 01 October 1990

[Echocardiographic examination after radical correction of the tetralogy of Fallot]

scientific article published on 01 January 1981

[Effectiveness of nifedipine on exercise tolerance in patients with angina pectoris. Comparison with a nitroderivative and a beta-blocking agent]

scientific article published on 01 January 1977

[Orally administered nitroderivates: efficacy and duration of the effects of isosorbide dinitrate (author's transl)]

scientific article published on 01 January 1976

miR-579-3p controls melanoma progression and resistance to target therapy

scientific article published on 08 August 2016

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