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List of works by Giovanni Sarnelli

Acetonic Extract from the Feijoa sellowiana Berg. Fruit Exerts Antioxidant Properties and Modulates Disaccharidases Activities in Human Intestinal Epithelial Cells

scientific article published on 10 May 2016

Acid exposure and altered acid clearance in GERD patients treated for Helicobacter pylori infection

scientific article

Acute diverticulitis: surgery timing in elderly patients.

scientific article published on 16 September 2013

Advances in our understanding of the pathology of chronic intestinal pseudo-obstruction

scientific article

Allele-specific transcriptional activity of the variable number of tandem repeats of the inducible nitric oxide synthase gene is associated with idiopathic achalasia.

scientific article published on 08 July 2016

Anti-HuD-induced neuronal apoptosis underlying paraneoplastic gut dysmotility

scientific article published on 01 July 2003

Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice.

scientific article published on 7 September 2017

Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration

scientific article

Bacterial stimuli activate nitric oxide colonic mucosal production in diverticular disease. Protective effects of L. casei DG® (Lactobacillus paracasei CNCM I-1572).

scientific article published on 11 December 2016

CRF-induced calcium signaling in guinea pig small intestine myenteric neurons involves CRF-1 receptors and activation of voltage-sensitive calcium channels.

scientific article published on 29 December 2005

Cannabidiol inhibits SARS-Cov-2 spike (S) protein-induced cytotoxicity and inflammation through a PPARγ-dependent TLR4/NLRP3/Caspase-1 signaling suppression in Caco-2 cell line

scientific article published on 12 October 2021

Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis

scientific article

Cannabidiol restores intestinal barrier dysfunction and inhibits the apoptotic process induced by Clostridium difficile toxin A in Caco-2 cells

scientific article published on 13 March 2017

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

scientific article

Complementary and alternative treatment in functional dyspepsia

scientific article published on 2 August 2017

Completeness of total mesorectum excision of laparoscopic versus robotic surgery: a review with a meta-analysis

scientific article published on 06 May 2019

Correlation between oesophageal acid exposure and dyspeptic symptoms in patients with nonerosive reflux disease

scientific article published in April 2008

Cortical representation of different taste modalities on the gustatory cortex: A pilot study

scientific article published on 27 December 2017

Detection of colonic dysplasia in patients with ulcerative colitis using a targeted fluorescent peptide and confocal laser endomicroscopy: A pilot study

scientific article published on 30 June 2017

Diet and functional dyspepsia: Clinical correlates and therapeutic perspectives

scientific article published on 01 February 2020

Editorial overview

scientific article published on 24 November 2018

Effect of carbonation on brain processing of sweet stimuli in humans

scientific article published on 25 May 2013

Effect of chronic administration of tacrolimus and cyclosporine on human gastrointestinal permeability.

scientific article published in May 2003

Effect of intranasal sumatriptan on gastric tone and sensitivity to distension

scientific article

Effects of carbonated water on functional dyspepsia and constipation

scientific article published on 01 September 2002

Effects of long-term PPI treatment on producing bowel symptoms and SIBO.

scientific article

Endocannabinoid-related compounds in gastrointestinal diseases.

scientific article

Endocannabinoids in the treatment of gasytrointestinal inflammation and symptoms

scientific article published on 12 September 2018

Endoscopic treatment of esophageal achalasia.

scientific article

Enteric Glial-Derived S100B Protein Stimulates Nitric Oxide Production in Celiac Disease

scientific article published on 20 June 2007

Enteric glia: A new player in inflammatory bowel diseases

scientific article published on 01 December 2015

Enteroglial-derived S100B protein integrates bacteria-induced Toll-like receptor signalling in human enteric glial cells

scientific article

Eosinophilic esophagitis: From pathophysiology to treatment

scientific article

Food intake and gastrointestinal motility. A complex interplay

scientific article published on 01 August 2004

Functional dyspepsia symptoms, gastric emptying and satiety provocative test: analysis of relationships

scientific article published on 01 October 2001

Gastroduodenal lesions and Helicobacter pylori infection in dyspeptic patients with and without chronic renal failure.

scientific article published in February 2005

Gastrointestinal regulation of food intake: do gut motility, enteric nerves and entero-hormones play together?

scientific article published on December 2011

Genetic contribution to motility disorders of the upper gastrointestinal tract.

scientific article

Genetic variation in the lymphotoxin-α (LTA)/tumour necrosis factor-α (TNFα) locus as a risk factor for idiopathic achalasia

scientific article published on 20 November 2013

Good adherence to mediterranean diet can prevent gastrointestinal symptoms: A survey from Southern Italy.

scientific article

HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system.

scientific article published on 10 August 2017

HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia

scientific article published on 24 March 2018

High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors

scientific article published on 16 May 2021

Impact of genetic polymorphisms on the pathogenesis of achalasia: an age-dependent paradigm?

scientific article published on 01 June 2009

Incidence and risk factors of portomesenteric venous thrombosis after colorectal surgery for cancer in the elderly population

scientific article published on 19 November 2019

Increased mucosal nitric oxide production in ulcerative colitis is mediated in part by the enteroglial-derived S100B protein.

scientific article published on 24 June 2009

Increased severity of dyspeptic symptoms related to mental stress is associated with sympathetic hyperactivity and enhanced endocrine response in patients with postprandial distress syndrome.

scientific article published on 21 August 2012

Influence of sildenafil on gastric sensorimotor function in humans

scientific article published in November 2004

Inhibitory effects of galanin on evoked [Ca2+]i responses in cultured myenteric neurons.

scientific article

Irritable bowel syndrome and food interaction.

scientific article

Ketogal: A Derivative Ketorolac Molecule with Minor Ulcerogenic and Renal Toxicity.

scientific article published on 6 November 2017

Lathyrus sativus diamine oxidase counteracts histamine-induced cell proliferation, migration and pro-angiogenic mediators release in human colon adenocarcinoma cell line Caco-2

scientific article published on 29 May 2019

Leaky gut, dysbiosis, and enteric glia activation: the trilogy behind the intestinal origin of Parkinson's disease

scientific article published on 01 June 2020

Manometric study of hiatal hernia and its correlation with esophageal peristalsis

scientific article published on 01 September 1999

Mild dehydration in dyspeptic athletes is able to increase gastrointestinal symptoms: Protective effects of an appropriate hydration

scientific article published on 01 January 2019

Myenteric neuronal loss in rats with experimental colitis: role of tissue transglutaminase-induced apoptosis

scientific article published on 16 July 2008

Nicotinamide methylation and hepatic energy reserve: a study by liver perfusion in vitro

scientific article published on October 1995

Oesophageal acid exposure and altered neurocardiac function in patients with GERD and idiopathic cardiac dysrhythmias

scientific article published on 01 July 2006

Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action

scientific article published on 19 May 2022

Palmitoylethanolamide Exerts Antiproliferative Effect and Downregulates VEGF Signaling in Caco-2 Human Colon Carcinoma Cell Line Through a Selective PPAR-α-Dependent Inhibition of Akt/mTOR Pathway.

scientific article published on March 2016

Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner

scientific article

Palmitoylethanolamide Regulates Production of Pro-Angiogenic Mediators in a Model of β Amyloid-Induced Astrogliosis In Vitro

scientific article

Palmitoylethanolamide improves colon inflammation through an enteric glia/toll like receptor 4-dependent PPAR-α activation

scientific article published on 30 September 2013

Partially hydrolyzed guar gum in the treatment of irritable bowel syndrome with constipation: effects of gender, age, and body mass index

scientific article

Pentamidine niosomes thwart S100B effects in human colon carcinoma biopsies favouring wtp53 rescue

scientific article published on 05 February 2020

Pharmacokinetic drug evaluation of rifaximin for treatment of diarrhea-predominant irritable bowel syndrome

scientific article published on 22 June 2018

Play in advance against neurodegeneration: exploring enteric glial cells in gut-brain axis during neurodegenerative diseases

scientific article published on 06 May 2019

Postprandial Gastrointestinal Function Differs after Acute Administration of Sourdough Compared with Brewer's Yeast Bakery Products in Healthy Adults

scientific article published on 01 February 2018

Proinflammatory stimuli activates human-derived enteroglial cells and induces autocrine nitric oxide production

scientific article published on 18 July 2011

Proton pump inhibitors prescribing following the introduction of generic drugs.

scientific article published on 09 June 2012

Pseudopneumoperitoneum in chronic intestinal pseudo-obstruction: A case report ⬇️

scientific article published on June 28, 2011

Rationale and evidences for treatment of symptomatic uncomplicated diverticular disease

scientific article published on 14 December 2016

Reproducibility of gastric barostat studies in healthy controls and in dyspeptic patients

scientific article published on 01 April 2001

Rifaximin Improves Clostridium difficile Toxin A-Induced Toxicity in Caco-2 Cells by the PXR-Dependent TLR4/MyD88/NF-κB Pathway

scientific article published on 9 May 2016

Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.

scientific article published on June 2016

Robotic versus laparoscopic approach to treat symptomatic achalasia: systematic review with meta-analysis

scientific article published on 01 December 2019

Role of diaphragmatic crura and lower esophageal sphincter in gastroesophageal reflux disease: manometric and pH-metric study of small hiatal hernia

scientific article published on 01 December 2001

S100B Inhibitor Pentamidine Attenuates Reactive Gliosis and Reduces Neuronal Loss in a Mouse Model of Alzheimer's Disease.

scientific article published on 29 July 2015

S100B Protein Stimulates Proliferation and Angiogenic Mediators Release through RAGE/pAkt/mTOR Pathway in Human Colon Adenocarcinoma Caco-2 Cells

scientific article published on 01 July 2019

S100B protein in the gut: The evidence for enteroglial-sustained intestinal inflammation ⬇️

scientific article published on March 14, 2011

S100B-p53 disengagement by pentamidine promotes apoptosis and inhibits cellular migration via aquaporin-4 and metalloproteinase-2 inhibition in C6 glioma cells

scientific article published on April 2015

Specific dyspeptic symptoms are associated with poor response to therapy in patients with gastroesophageal reflux disease.

scientific article published on 7 July 2016

Sterile carbon particle suspension vs India ink for endoscopic tattooing of colonic lesions: a randomized controlled trial

scientific article published on 30 October 2019

Sweetened carbonated drinks do not alter upper digestive tract physiology in healthy subjects

scientific article published on 26 March 2008

Symptom patterns and pathophysiological mechanisms in dyspeptic patients with and without Helicobacter pylori

scientific article

Symptom patterns can distinguish diverticular disease from irritable bowel syndrome

scientific article

Symptoms and pathophysiological correlations in patients with constipation and functional dyspepsia

scientific article published on 12 July 2005

Symptoms associated with impaired gastric emptying of solids and liquids in functional dyspepsia

scientific article published in April 2003

Taste and the Gastrointestinal tract: from physiology to potential therapeutic target for obesity

scientific article published on 12 April 2019

Thalassemic Trait Prevalence in Patients Affected by Psoriatic Arthritis in Anti-TNF Treatment

scientific article published on 01 November 2014

The 2018 ISDE achalasia guidelines

scientific article published on 01 September 2018

The Bitter Taste Receptor Agonist Quinine Reduces Calorie Intake and Increases the Postprandial Release of Cholecystokinin in Healthy Subjects.

scientific article

The HLA-DQβ1 insertion is a strong achalasia risk factor and displays a geospatial north-south gradient among Europeans ⬇️

scientific article published on 6 January 2016

The antiprotozoal drug pentamidine ameliorates experimentally induced acute colitis in mice

scientific article published on 23 December 2012

The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation

scientific article published on 27 December 2005

The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A reduce inflammation-induced hypermotility in mice.

scientific article

The impact of translational research on gastroenterology

scientific article published on 05 February 2014

The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production

scientific article published in April 2001

The treatment of achalasia patients with esophageal varices: an international study

scientific article published on 29 March 2019

Tissue ghrelin level and gastric emptying rate in adult patients with celiac disease.

scientific article published on 30 April 2008

Treatment of refractory and severe hypothyroidism with sublingual levothyroxine in liquid formulation

scientific article published on 13 July 2017

inPentasomes: An innovative nose-to-brain pentamidine delivery blunts MPTP parkinsonism in mice

scientific article published on 07 December 2018

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