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List of works by Mark D. Gorrell

3-dimensional imaging of collagen using second harmonic generation.

scientific article

A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2

scientific article published on 18 November 2020

A functional and biochemical analysis of bovine class II MHC antigens using monoclonal antibodies

scientific article published on 01 November 1987

A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling

scientific article published on 26 May 2011

A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation

scientific article published on 06 April 2014

Advances in understanding the expression and function of dipeptidyl peptidase 8 and 9

scientific article

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis

An enzyme immunoassay for bovine brucellosis using a monoclonal antibody specific for field strains of Brucella abortus

scientific article published on 01 January 1984

Animal models for hepatocellular carcinoma

scientific article published on 10 August 2018

Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted β propeller domain

scientific article published on 01 December 1999

CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes.

scientific article

Circulating dipeptidyl peptidase-4 activity correlates with measures of hepatocyte apoptosis and fibrosis in non-alcoholic fatty liver disease in type 2 diabetes mellitus and obesity: A dual cohort cross-sectional study

scientific article published on 28 October 2014

Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease.

scientific article

Circulating fibroblast activation protein and dipeptidyl peptidase 4 in rheumatoid arthritis and systemic sclerosis

scientific article

Cooperation of innate and adaptive immunity in the pathogenesis of biliary atresia: there's a killer on the run

scientific article published on 01 December 2009

Corrigendum to “Stromal cell-derived factors 1α and 1β, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8” [FEBS Lett. 582 (2008) 819-825]

scholarly article published in FEBS Letters

Covid-19 and co-morbidities: a role for Dipeptidyl Peptidase 4 (DPP4) in disease severity?

scientific article published on 11 May 2020

Cysticercosis: cellular immune responses during primary and secondary infection

scientific article published on 01 July 1990

DP8 and DP9 have extra-enzymatic roles in cell adhesion, migration and apoptosis

scientific article (publication date: 2006)

DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues.

scientific article published on 12 July 2013

Deletion of fibroblast activation protein provides atheroprotection

scientific article published on 13 May 2020

Design and synthesis of novel inhibitors of human kynurenine aminotransferase-I

scientific article published on 10 January 2012

Diabetes and Nonalcoholic Fatty Liver Disease: A Pathogenic Duo ⬇️

scientific article published on December 13, 2012

Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis

scientific article published on 22 December 2010

Different inhibition mechanisms of dipeptidyl peptidase IV by tryptophan containing peptides and amides

scientific article published in January 2003

Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites

scientific article published in May 2003

Differential chemokine receptor expression and usage by pre-cDC1 and pre-cDC2

scientific article published on 20 July 2018

Dipeptidyl Peptidase 8

Dipeptidyl peptidase 8 has post-proline dipeptidyl aminopeptidase and prolyl endopeptidase activities

scientific article published on January 2006

Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes

scientific article published on 27 February 2016

Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity

scientific article

Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin.

scientific article

Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches.

scientific article published on 13 July 2016

Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders

scientific journal article

Dipeptidyl peptidase IV gene family. The DPIV family

scientific article

Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease

scientific article

Discoidin domain receptor 1: isoform expression and potential functions in cirrhotic human liver.

scientific article published in March 2011

Expression of the rat CD26 antigen (dipeptidyl peptidase IV) on subpopulations of rat lymphocytes

scientific article published on 01 April 1991

Extra-enzymatic roles of DPIV and FAP in cell adhesion and migration on collagen and fibronectin

scientific article published on 01 January 2006

Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis

scientific article (publication date: June 2006)

Fibroblast activation protein and chronic liver disease

scientific article published on January 2008

Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line

scientific article published on October 2005

Fibroblast activation protein is dispensable in the anti-influenza immune response in mice.

scientific article

Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis

scientific article published on 01 June 1999

First bite

scientific article

Fooling the liver: malaria incognito.

scientific article published in March 2007

Gene array analysis and the liver.

scientific article

Gene expression characteristics of a cystic fibrosis epidemic strain of Pseudomonas aeruginosa during biofilm and planktonic growth

scientific article

Gene expression profiling of alcoholic liver disease in the baboon (Papio hamadryas) and human liver

scientific article published in December 2003

Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse

scientific article published in January 2002

Hepatocellular carcinoma: Mouse models and the potential roles of proteases

scientific article published on April 2016

High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate

scientific article published on 18 January 2017

Homology modeling of human kynurenine aminotransferase III and observations on inhibitor binding using molecular docking.

scientific article published in January 2014

Hypoxia Regulates DPP4 Expression, Proteolytic Inactivation, and Shedding from Ovarian Cancer Cells

scientific article published on 30 October 2020

Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics.

scientific article

Identification of novel dipeptidyl peptidase 9 substrates by two-dimensional differential in-gel electrophoresis

scientific article published on 14 July 2015

Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity

scientific article published on 13 May 2019

Impaired glucose tolerance and incretins in chronic liver disease

scientific article

Incretin-based therapies--review of the physiology, pharmacology and emerging clinical experience.

scientific article published on April 2011

Inflammation and repair in viral hepatitis C.

scientific article published on June 2008

Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives

scientific article published on 14 December 2017

Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition

scientific article published on 28 September 2009

Insights into the Pathobiology of Hepatitis C Virus-Associated Cirrhosis

scientific article (publication date: February 2002)

Intrahepatic expression of collagen and fibroblast activation protein (FAP) in hepatitis C virus infection

scientific article (publication date: 2003)

Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection

scientific article (publication date: April 2002)

Intrahepatic gene expression in human alcoholic hepatitis.

scientific article

Kynurenine Aminotransferases and the Prospects of Inhibitors for the Treatment of Schizophrenia

scientific article published on 07 June 2015

Langerhans cells in the development of skin cancer: a qualitative and quantitative comparison of cell markers in normal, acanthotic and neoplastic ovine skin

scientific article published on February 1997

Lentivirus induced arthritis in animals.

scientific article published in January 1992

Letter to Editor.

scientific article published on 14 December 2017

Liver fibrosis: the hepatocyte revisited

scientific article published on 01 November 2007

Lower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity

scientific article published on 11 March 2015

Lymphocyte phenotypes in the intestinal mucosa of sheep infected with Trichostrongylus colubriformis

scientific article published on 01 May 1988

Lymphocyte subpopulations in the blood of sheep persistently infected with border disease virus

scientific article

Lymphocyte subpopulations of sheep in protective immunity to Taenia hydatigena

scientific article published on 01 March 1989

Major histocompatibility complex antigens in normal, acanthotic and neoplastic ovine skin: an association been tumor invasiveness and low level MHC class I expression

scientific article published on April 1995

Molecular Analyses of Human and Rat Dipeptidyl Peptidase IV ⬇️

scientific article published on January 1, 1997

Molecular characterization of a novel dipeptidyl peptidase like 2-short form (DPL2-s) that is highly expressed in the brain and lacks dipeptidyl peptidase activity

scientific article

Molecular chimeras and mutational analysis in the prolyl oligopeptidase gene family

scientific article published in January 2003

Molecular pathogenesis of liver disease: an approach to hepatic inflammation, cirrhosis and liver transplant tolerance.

scientific article

Multiple liver insults synergize to accelerate experimental hepatocellular carcinoma.

scientific article published on 6 July 2018

Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma

scientific article published on 24 November 2015

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

scientific article

Non-Invasive Fluorescent Monitoring of Ovarian Cancer in an Immunocompetent Mouse Model

scientific article published on 31 December 2018

Novel differential gene expression in human cirrhosis detected by suppression subtractive hybridization

scientific article

Pathogenesis and management of alcoholic hepatitis.

scientific article published on December 2003

Porcine cells express more than one functional ligand for the human lymphocyte activating receptor NKG2D.

scientific article published in September 2008

Presence of a distinct CD8+ and CD5- leucocyte subpopulation in the sheep liver

scientific article published on 01 August 1988

Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs.

scientific article published on 08 December 2013

Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.

scientific article published on May 2013

Regulation of the Receptor Specificity and Function of the Chemokine RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted) by Dipeptidyl Peptidase IV (CD26)-mediated Cleavage ⬇️

scientific article published on December 1, 1997

SMART amplification maintains representation of relative gene expression: quantitative validation by real time PCR and application to studies of alcoholic liver disease in primates.

scientific article

Sheep MHC class II molecules. I. Immunochemical characterization

scientific article published on 01 December 1987

Soluble CD26 / Dipeptidyl Peptidase IV Enhances Human Lymphocyte Proliferation In Vitro Independent of Dipeptidyl Peptidase Enzyme Activity and Adenosine Deaminase Binding

scientific article published on 01 February 2011

Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8

scientific article

Structural requirements for catalysis, expression, and dimerization in the CD26/DPIV gene family

scientific article (publication date: 28 January 2003)

Structure and function in dipeptidyl peptidase IV and related proteins

scientific article

T and B lymphocyte subsets in spermatic granulomas in five rams

scientific article

Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality

scientific article

The challenge of developing novel pharmacological therapies for non-alcoholic steatohepatitis

scientific article published on July 2010

The dipeptidyl peptidase IV family in cancer and cell biology.

scientific article published on 13 January 2010

The distribution of lymphocyte subpopulations in normal and acanthotic ovine skin

scientific article published in January 1995

The hepatic transcriptome in human liver disease

scientific article published on 7 November 2006

The in vivo expression of dipeptidyl peptidases 8 and 9.

scientific article published on 06 July 2009

The long and the short of interferon-gamma–inducible protein 10 in hepatitis C virus infection ⬇️

scientific article published on November 1, 2011

The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury.

scientific article published on 30 November 2016

Transcriptome analyses and biofilm-forming characteristics of a clonal Pseudomonas aeruginosa from the cystic fibrosis lung

scientific article published on 01 December 2008

Tumour necrosis factor and interleukin 6 production during interaction between activated CD4+ lymphocytes and simian immunodeficiency virus-infected macrophages

scientific article published on May 1992

Two highly conserved glutamic acid residues in the predicted β propeller domain of dipeptidyl peptidase IV are required for its enzyme activity

scientific article published on 01 September 1999

Understanding fibroblast activation protein (FAP): substrates, activities, expression and targeting for cancer therapy.

scientific article published on 24 March 2014

Up-regulation of proproliferative genes and the ligand/receptor pair placental growth factor and vascular endothelial growth factor receptor 1 in hepatitis C cirrhosis

scientific article published on 01 September 2007

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