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List of works by Chris Boutell

A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7

scientific article

A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro

scientific article

A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication

scientific article

A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses

scientific journal article

A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence

scientific article

CENP-B dynamics at centromeres is regulated by a SUMOylation/ubiquitination and proteasomal-dependent degradation mechanism involving the SUMO-targeted ubiquitin E3 ligase RNF4

Comparative proteomics identifies Schlafen 5 (SLFN5) as a herpes simplex virus restriction factor that suppresses viral transcription

scientific article published on 11 January 2021

Comparison of the biological and biochemical activities of several members of the alphaherpesvirus ICP0 family of proteins

scientific article

Correction: Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection.

scientific article

Depletion of intracellular zinc inhibits the ubiquitin ligase activity of viral regulatory protein ICP0 and restricts herpes simplex virus 1 replication in cell culture

scientific article published on 25 January 2012

Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection

scientific article published on 8 January 2018

Functional characterization of residues required for the herpes simplex virus 1 E3 ubiquitin ligase ICP0 to interact with the cellular E2 ubiquitin-conjugating enzyme UBE2D1 (UbcH5a)

scientific article published on 21 March 2012

Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells

scientific article

Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility

scientific article published on 10 January 2006

HSV-1 ICP0: paving the way for viral replication

scientific article (publication date: April 2011)

Herpes simplex virus type 1 ICP0 phosphorylation mutants impair the E3 ubiquitin ligase activity of ICP0 in a cell type-dependent manner

scientific article published on 20 August 2008

Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro

scientific article published on January 2002

Herpes simplex virus type 1 induces CD83 degradation in mature dendritic cells with immediate-early kinetics via the cellular proteasome

scientific article published on 11 April 2007

Herpes simplex virus type 1 infection induces the stabilization of p53 in a USP7- and ATM-independent manner

scientific article published on August 2004

Host and viral determinants of Mx2 antiretroviral activity

scientific article

Identification of a novel higher molecular weight isoform of USP7/HAUSP that interacts with the Herpes simplex virus type-1 immediate early protein ICP0.

scientific article published on 17 July 2008

In memoriam--Richard M. Elliott (1954-2015)

scientific article

Inhibition of hepatitis C virus RNA replication by ISG15 does not require its conjugation to protein substrates by the HERC5 E3 ligase

scientific article published on 10 September 2015

Interplay between viruses and host sumoylation pathways

scientific article published on 29 April 2013

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

scientific article

New regulators of the BRCA1 response to genotoxic stress.

scientific article published on 18 May 2010

Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response

scientific article published on 02 March 2016

PML residue lysine 160 is required for the degradation of PML induced by herpes simplex virus type 1 regulatory protein ICP0

scientific article

Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0.

scientific article published on February 2004

Proteomic analysis of cells in the early stages of herpes simplex virus type-1 infection reveals widespread changes in the host cell proteome

scientific article

Reciprocal activities between herpes simplex virus type 1 regulatory protein ICP0, a ubiquitin E3 ligase, and ubiquitin-specific protease USP7.

scientific article published on October 2005

Regulation of alphaherpesvirus infections by the ICP0 family of proteins

scientific article published on 12 December 2012

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1.

scientific article published on 20 April 2016

SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes

scientific article

Sequences related to SUMO interaction motifs in herpes simplex virus 1 protein ICP0 act cooperatively to stimulate virus infection

scientific article published on 18 December 2013

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

scientific article

The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells

scientific article published on 22 December 2020

The herpes simplex virus triplex protein, VP23, exists as a molten globule.

scientific article

The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.

scientific article

The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection

scientific article published on 22 March 2019

The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0.

scientific article

Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain

scientific article published on 7 March 2012

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