List of works - Antonello Pietrangelo

3-Hydroxy-(4H)-benzopyran-4-ones as potential iron chelating agents in vivo

scientific article published on 01 November 2001

A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis

scientific article

Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.

scientific article published on 6 January 2016

Altered hepatic BMP signaling pathway in human HFE hemochromatosis

scientific article published on 21 September 2010

An unfortunate case of post-ERCP complications.

scientific article

Antioxidant activity of silybin in vivo during long-term iron overload in rats

scientific article published on 01 December 1995

Association between celiac disease and idiopathic dilated cardiomyopathy: a case report

scientific article published on 25 August 2010

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

scientific article published on March 2009

C/EBP-beta/LAP controls down-regulation of albumin gene transcription during liver regeneration

scientific article published on 01 September 1996

Clinical impact of application of risk assessment models (Padua Prediction Score and Improve Bleeding Score) on venous thromboembolism, major hemorrhage and health expenditure associated with pharmacologic VTE prophylaxis: a "real life" prospective

scientific article published on 03 March 2018

Corrigendum to "Ferroportin disease: A systematic meta-analysis of clinical and molecular findings" J. Hepatol. 2010 Nov;53(5):941-949.

scientific article published on 25 May 2011

DNA repair in lymphocytes from humans and rats with chronic iron overload

scientific article published in July 1988

Design, synthesis, and physicochemical and biological characterization of a new iron chelator of the family of hydroxychromenes.

scientific article published in December 2002

Diacerhein blocks iron regulatory protein activation in inflamed human monocytes.

scientific article published on January 1998

Disease progression and liver cancer in the ferroportin disease.

scientific article published on July 2007

Duodenal ferritin synthesis in genetic hemochromatosis

scientific article published on 01 January 1995

Duodenal metal-transporter (DMT-1, NRAMP-2) expression in patients with hereditary haemochromatosis

scientific article published on 01 June 1999

ER stress controls iron metabolism through induction of hepcidin

scientific article

Enhanced hepatic collagen type I mRNA expression into fat-storing cells in a rodent model of hemochromatosis

scientific article published on 01 March 1994

Evaluating the association of serum ferritin and hepatic iron with disease severity in non-alcoholic fatty liver disease

scientific article published on 27 March 2019

Expression of messenger RNA for liver functions following 70% and 90% hepatectomy

scientific article published on July 1996

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

scientific article published in May 2001

Ferroportin disease: a systematic meta-analysis of clinical and molecular findings

scientific article

Ferroportin disease: pathogenesis, diagnosis and treatment.

scientific article published on 3 November 2017

Ferroportin is a monomer in vivo in mice

scientific article published on 27 December 2005

Ferroportin-related haemochromatosis associated with novel Y64H mutation of the SCL40A1 gene

scientific article published on 19 October 2014

Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy

scientific article published on 01 April 2001

Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y

scientific article published on 01 April 2002

G80S-linked ferroportin disease: the first clinical description in a Greek family

scientific article published on 16 April 2008

Gene expression of urea cycle enzymes following two-thirds partial hepatectomy in the rat

scientific article published on 01 March 1995

Genetics in liver diseases

scientific article published on 04 April 2007

Genetics, Genetic Testing, and Management of Hemochromatosis: 15 Years Since Hepcidin

scientific article published on 08 July 2015

Gluconeogenic signals regulate iron homeostasis via hepcidin in mice

scientific article published on 17 December 2013

HJV gene mutations in European patients with juvenile hemochromatosis

scientific article published on 01 May 2005

Haemochromatosis

scientific article

Haemochromatosis

scientific article published on 05 April 2018

Haptoglobin modifies the hemochromatosis phenotype in mice

scientific article published on 21 December 2004

Hemochromatosis 1998: is one gene enough?

scientific article published on 01 September 1998

Hemochromatosis and hemojuvelin G320V homozygosity in a Hungarian woman

scientific article published on 17 March 2010

Hemochromatosis gene modifies course of hepatitis C viral infection.

scientific article

Hemochromatosis: an endocrine liver disease.

scientific article published on October 2007

Hepatic stellate cells are not subjected to oxidant stress during iron-induced fibrogenesis in rodents

scientific article published in June 1998

Hepatitis B virus DNA integration in tumour tissue of a non-cirrhotic HFE-haemochromatosis patient with hepatocellular carcinoma.

scientific article

Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription

scientific article published on 9 October 2007

Hepatocyte growth factor/hepatopoietin A is expressed in fat-storing cells from rat liver but not myofibroblast-like cells derived from fat-storing cells

scientific article published on January 1992

Hepcidin Expression Does Not Rescue the Iron-Poor Phenotype of Kupffer Cells in Hfe-Null Mice After Liver Transplantation

Hepcidin in human iron disorders: therapeutic implications.

scientific article published on 26 August 2010

Hereditary hemochromatosis

scientific article published on 01 January 2006

Hereditary hemochromatosis

scientific article published on 27 May 2006

Hereditary hemochromatosis--a new look at an old disease

scientific article

Heterogeneity of hemochromatosis in Italy

scientific article published on 01 May 1998

Homeostatic regulation of hepatocyte nuclear transcription factor 1 expression in cultured hepatoma cells.

scientific article

Huh-7: a human "hemochromatotic" cell line.

scientific article

Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis

scientific article published on 25 March 2016

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB.

scientific article published on 5 March 2014

Impact of D181V and A69T on the function of ferroportin as an iron export pump and hepcidin receptor

scientific article published on 21 May 2014

Impaired iron transport activity of ferroportin 1 in hereditary iron overload

scientific article

Inherited metabolic disease of the liver

scientific article published on 01 May 2009

Iron Overload in the Liver of 2 Children: Nonalcoholic Steatohepatitis and Juvenile Hemochromatosis.

scientific article published on 6 January 2017

Iron and steatohepatitis.

scientific article published on March 2012

Iron and the liver

scientific article published on 01 January 2016

Iron chelation beyond transfusion iron overload.

scientific article published on December 2007

Iron in NASH, chronic liver diseases and HCC: how much iron is too much?

scientific article published on 04 December 2008

Iron regulatory proteins in pathobiology.

scientific article

Iron removal therapy in porphyria cutanea tarda: phlebotomy versus slow subcutaneous desferrioxamine infusion

scientific article published on 01 May 1986

Iron, friend or foe? "Freedom" makes the difference

scientific article published on 01 May 2000

Iron-induced oxidant stress in alcoholic liver fibrogenesis.

scientific article

Iron-induced oxidant stress in nonparenchymal liver cells: mitochondrial derangement and fibrosis in acutely iron-dosed gerbils and its prevention by silybin

scientific article published in February 2002

Juvenile hemochromatosis

scientific article published on 25 September 2006

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

article

Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload

scientific article published on 01 March 2005

Lack of coordinate control of ferritin and transferrin receptor expression during rat liver regeneration

scientific article published in July 1998

Lack of enterocyte iron accumulation in the ferroportin disease

scientific article published on 30 August 2005

Lipid composition and fluidity of liver mitochondria, microsomes and plasma membrane of rats with chronic dietary iron overload

scientific article published on 01 January 1990

Lipid composition and fluidity of liver plasma membranes from rats with chronic dietary iron overload

scientific article published on 01 August 1989

Liver gene expression during chronic dietary iron overload in rats

scientific article published on 01 May 1990

Magnetic resonance imaging to identify classic and nonclassic forms of ferroportin disease

scientific article published on 18 October 2006

Management of chronic viral hepatitis in patients with thalassemia: recommendations from an international panel.

scientific article published on 15 June 2010

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

scientific article published on 06 July 2020

Mechanisms of iron hepatotoxicity

scientific article published on 5 February 2016

Metal storage disorders. Forward

scientific article published on 01 August 2011

Missed treatment in an Italian HBV infected patients cohort: HBV RER.

scientific article published on 21 July 2016

Modulation of the synthesis of apolipoproteins in rat hepatoma cells

scientific article

Nitric-oxide-mediated activation of iron-regulatory protein controls hepatic iron metabolism during acute inflammation

scientific article published on 01 September 1995

Non-HFE hemochromatosis

scientific article published on 01 January 2004

Non-HFE hemochromatosis.

scientific article

Non-invasive assessment of hepatic iron overload: are we finally there?

scientific article published on 01 January 2005

Pathogens, Metabolic Adaptation, and Human Diseases--An Iron-Thrifty Genetic Model.

scientific article

Physiology of iron transport and the hemochromatosis gene.

scientific article

Reducing the risk of hospital admission: a call to action from the Italian Society of Internal Medicine

scientific article published on 10 July 2015

Regulation of hepatic transferrin, transferrin receptor and ferritin genes in human siderosis

scientific article published in December 1991

Response of young, aged and osteoarthritic human articular chondrocytes to inflammatory cytokines: molecular and cellular aspects

scientific article published in August 2002

STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.

scientific article published on 17 October 2006

Safety and efficacy of sucrosomial iron in inflammatory bowel disease patients with iron deficiency anemia

scientific article published on 29 November 2018

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

scientific article published on July 2011

Serum ferritin as a predictor of treatment outcome in patients with chronic hepatitis C.

scientific article published on 10 February 2009

Standard or branched-chain amino acid infusions as short-term nutritional support in liver cirrhosis?

scientific article published in July 1985

Strategies for liver support: from stem cells to xenotransplantation.

scientific article published in December 2004

The SMAD Pathway Is Required for Hepcidin Response During Endoplasmic Reticulum Stress

scientific article published on 2 August 2016

The ferroportin disease

scientific article published on 27 May 2014

The impact of inherited thrombophilia on liver transplantation

scientific article published on 01 April 2009

The iron regulatory proteins: targets and modulators of free radical reactions and oxidative damage.

scientific article

The penetrance of hemochromatosis: mice to the rescue

scientific article published on 01 February 2007

The porphyrias: pathophysiology ⬇️

scientific article published on October 1, 2010

The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression

scientific article (publication date: November 2003)

Unravelling the Complexity of Inherited Retinal Dystrophies Molecular Testing: Added Value of Targeted Next-Generation Sequencing.

scientific article published on 29 December 2016

What to start with in first line treatment of chronic hepatitis B patients: an Italian multicentre observational cohort, HBV-RER study group

scientific article published on June 2017

List of works by Antonello Pietrangelo

3-Hydroxy-(4H)-benzopyran-4-ones as potential iron chelating agents in vivo

A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis

Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.

Altered hepatic BMP signaling pathway in human HFE hemochromatosis

An unfortunate case of post-ERCP complications.

Antioxidant activity of silybin in vivo during long-term iron overload in rats

Association between celiac disease and idiopathic dilated cardiomyopathy: a case report

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

C/EBP-beta/LAP controls down-regulation of albumin gene transcription during liver regeneration

Clinical impact of application of risk assessment models (Padua Prediction Score and Improve Bleeding Score) on venous thromboembolism, major hemorrhage and health expenditure associated with pharmacologic VTE prophylaxis: a "real life" prospective

Corrigendum to "Ferroportin disease: A systematic meta-analysis of clinical and molecular findings" J. Hepatol. 2010 Nov;53(5):941-949.

DNA repair in lymphocytes from humans and rats with chronic iron overload

Design, synthesis, and physicochemical and biological characterization of a new iron chelator of the family of hydroxychromenes.

Diacerhein blocks iron regulatory protein activation in inflamed human monocytes.

Disease progression and liver cancer in the ferroportin disease.

Duodenal ferritin synthesis in genetic hemochromatosis

Duodenal metal-transporter (DMT-1, NRAMP-2) expression in patients with hereditary haemochromatosis

ER stress controls iron metabolism through induction of hepcidin

Enhanced hepatic collagen type I mRNA expression into fat-storing cells in a rodent model of hemochromatosis

Evaluating the association of serum ferritin and hepatic iron with disease severity in non-alcoholic fatty liver disease

Expression of messenger RNA for liver functions following 70% and 90% hepatectomy

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

Ferroportin disease: a systematic meta-analysis of clinical and molecular findings

Ferroportin disease: pathogenesis, diagnosis and treatment.

Ferroportin is a monomer in vivo in mice

Ferroportin-related haemochromatosis associated with novel Y64H mutation of the SCL40A1 gene

Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy

Frequency of the S65C mutation of HFE and iron overload in 309 subjects heterozygous for C282Y

G80S-linked ferroportin disease: the first clinical description in a Greek family

Gene expression of urea cycle enzymes following two-thirds partial hepatectomy in the rat

Genetics in liver diseases

Genetics, Genetic Testing, and Management of Hemochromatosis: 15 Years Since Hepcidin

Gluconeogenic signals regulate iron homeostasis via hepcidin in mice

HJV gene mutations in European patients with juvenile hemochromatosis

Haemochromatosis

Haemochromatosis

Haptoglobin modifies the hemochromatosis phenotype in mice

Hemochromatosis 1998: is one gene enough?

Hemochromatosis and hemojuvelin G320V homozygosity in a Hungarian woman

Hemochromatosis gene modifies course of hepatitis C viral infection.

Hemochromatosis: an endocrine liver disease.

Hepatic stellate cells are not subjected to oxidant stress during iron-induced fibrogenesis in rodents

Hepatitis B virus DNA integration in tumour tissue of a non-cirrhotic HFE-haemochromatosis patient with hepatocellular carcinoma.

Hepatitis C virus-induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription

Hepatocyte growth factor/hepatopoietin A is expressed in fat-storing cells from rat liver but not myofibroblast-like cells derived from fat-storing cells

Hepcidin Expression Does Not Rescue the Iron-Poor Phenotype of Kupffer Cells in Hfe-Null Mice After Liver Transplantation

Hepcidin in human iron disorders: therapeutic implications.

Hereditary hemochromatosis

Hereditary hemochromatosis

Hereditary hemochromatosis--a new look at an old disease

Heterogeneity of hemochromatosis in Italy

Homeostatic regulation of hepatocyte nuclear transcription factor 1 expression in cultured hepatoma cells.

Huh-7: a human "hemochromatotic" cell line.

Hyperhomocysteinemia and MTHFR C677T polymorphism in patients with portal vein thrombosis complicating liver cirrhosis

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB.

Impact of D181V and A69T on the function of ferroportin as an iron export pump and hepcidin receptor

Impaired iron transport activity of ferroportin 1 in hereditary iron overload

Inherited metabolic disease of the liver

Iron Overload in the Liver of 2 Children: Nonalcoholic Steatohepatitis and Juvenile Hemochromatosis.

Iron and steatohepatitis.

Iron and the liver

Iron chelation beyond transfusion iron overload.

Iron in NASH, chronic liver diseases and HCC: how much iron is too much?

Iron regulatory proteins in pathobiology.

Iron removal therapy in porphyria cutanea tarda: phlebotomy versus slow subcutaneous desferrioxamine infusion

Iron, friend or foe? "Freedom" makes the difference

Iron-induced oxidant stress in alcoholic liver fibrogenesis.

Iron-induced oxidant stress in nonparenchymal liver cells: mitochondrial derangement and fibrosis in acutely iron-dosed gerbils and its prevention by silybin

Juvenile hemochromatosis

Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes

Kupffer cells and macrophages are not required for hepatic hepcidin activation during iron overload

Lack of coordinate control of ferritin and transferrin receptor expression during rat liver regeneration

Lack of enterocyte iron accumulation in the ferroportin disease

Lipid composition and fluidity of liver mitochondria, microsomes and plasma membrane of rats with chronic dietary iron overload

Lipid composition and fluidity of liver plasma membranes from rats with chronic dietary iron overload

Liver gene expression during chronic dietary iron overload in rats

Magnetic resonance imaging to identify classic and nonclassic forms of ferroportin disease

Management of chronic viral hepatitis in patients with thalassemia: recommendations from an international panel.

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia