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List of works by Jasper Stevens

A new minimal-stress freely-moving rat model for preclinical studies on intranasal administration of CNS drugs.

scientific article published on 19 May 2009

A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds

scientific article published on 11 May 2017

An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.

scientific article published on 20 February 2017

Association between individual cholesterol and proteinuria response and exposure to atorvastatin or rosuvastatin

scientific article published on 30 September 2019

Bayesian model of Hamilton Depression Rating Score (HDRS) with memantine augmentation in bipolar depression

scientific article published on March 2013

Biodistribution and translational pharmacokinetic modeling of a human recombinant alkaline phosphatase

scientific article published on 28 August 2015

Colistin methanesulfonate infusion solutions are stable over time and suitable for home administration

scientific article published on 18 March 2017

Defining the Optimal Dose of Atrasentan by Evaluating the Exposure-Response Relationships of Albuminuria and Bodyweight.

scientific article published on 30 March 2018

Effect of Food on the Pharmacokinetics of 2 Formulations of DRL-17822, a Novel Selective Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Males

scientific article published on 10 June 2019

Elderly patients, classical monoamine oxidase inhibitors and intercurrent somatic diseases

scientific article published on October 4, 2003

Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial

scientific article published on 01 October 2019

Exposure-Response relationships of dapagliflozin on cardio-renal risk markers and adverse events: a pooled analysis of 13 phase II/III trials

scientific article published on 20 April 2020

Exposure-response relationships for the sodium-glucose co-transporter-2 inhibitor dapagliflozin with regard to renal risk markers

scientific article published on 27 January 2020

First in human study with a prodrug of galantamine: Improved benefit-risk ratio?

scientific article published on 20 January 2016

Fosfomycin as a potential therapy for the treatment of systemic infections: a population pharmacokinetic model to simulate multiple dosing regimens

scientific article published in February 2018

Fosfomycin, an old antibiotic with new possibilities

scientific article published on January 2017

Fosfomycin: Pharmacological, Clinical and Future Perspectives.

scientific article published on 31 October 2017

How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review.

scientific article

Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach

scientific article published on 25 November 2015

Inter-individual variability in atrasentan exposure partly explains variability in kidney protection and fluid retention responses: a post-hoc analysis of the SONAR trial

scientific article published on 12 November 2020

Levofloxacin-Induced QTc Prolongation Depends on the Time of Drug Administration.

scientific article published on August 2016

Mechanism-based PK-PD model for the prolactin biological system response following an acute dopamine inhibition challenge: quantitative extrapolation to humans.

scientific article published on 12 July 2012

Model informed quantification of the feed-forward stimulation of growth hormone by growth hormone-releasing hormone

scientific article published on 22 February 2020

Model-based exposure-response analysis to quantify age related differences in the response to scopolamine in healthy subjects

scientific article published on 7 June 2016

Neonatal withdrawal symptoms following the use of clomipramine during pregnancy

scientific article published on July 25, 1992

Online solid phase extraction with liquid chromatography-tandem mass spectrometry to analyze remoxipride in small plasma-, brain homogenate-, and brain microdialysate samples.

scientific article published on 26 February 2010

Optimizing the glutamatergic challenge model for psychosis, using S+ -ketamine to induce psychomimetic symptoms in healthy volunteers.

scientific article

Parkinsonism following addition of fluoxetine to the treatment with neuroleptics or carbamazepine

scientific article published on February 15, 1992

Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers

scientific article

Pharmacokinetic/pharmaco-dynamic modelling and simulation of the effects of different cannabinoid receptor type 1 antagonists on Δ(9)-tetrahydrocannabinol challenge tests

scientific article

Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.

scientific article published on 07 December 2016

Pharmacokinetics of rituximab in a pediatric patient with therapy-resistant nephrotic syndrome

scientific article published on 9 June 2015

Pharmacokinetics, pharmacodynamics and safety of CEP-26401, a high-affinity histamine-3 receptor antagonist, following single and multiple dosing in healthy subjects

scientific article

Pharmacological interactions between brivaracetam and ethanol in healthy males

scientific article published on 20 September 2016

Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects

scientific article published on 13 August 2018

Population Pharmacokinetics of Prednisolone in Relation to Clinical Outcome in Children With Nephrotic Syndrome

scientific article

Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling

scientific article published on 04 April 2020

Quantifying Beta-Galactosylceramide Kinetics in Cerebrospinal Fluid of Healthy Subjects Using Deuterium Labeling

scientific article published on 15 October 2016

Response to letter to editor

scientific article published on 10 February 2016

Safety and dose-dependency of eptacog beta (activated) in a dose escalation study of non-bleeding congenital haemophilia A or B patients, with or without inhibitors.

scientific article published on 5 October 2017

Systemic and direct nose-to-brain transport pharmacokinetic model for remoxipride after intravenous and intranasal administration.

scientific article published on 8 September 2011

The Pharmacodynamic Effects of a Dopamine-Somatostatin Chimera Agonist on the Cardiovascular System

scientific article published on 01 August 2019

The effect of food and formulation on the population pharmacokinetics of CETP inhibitor DRL-17822 in healthy male volunteers

scientific article published on 06 April 2020

The influence of personality on the sensitivity to subjective effects of Δ9-tetrahydrocannabinol

scientific article published on 01 December 2014

The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.

scientific article published on 9 November 2016

UHPLC-MS/MS method for iohexol determination in human EDTA and lithium-heparin plasma, human urine and in goat- and pig EDTA plasma

scientific article published on 22 July 2020

Use of population approach non-linear mixed effects models in the evaluation of biosimilarity of monoclonal antibodies.

scientific article published on 11 August 2016

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