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List of works by Ian Wilson

19F and 1H magnetic resonance strategies for metabolic studies on fluorinated xenobiotics: Application to flurbiprofen [2-(2-fluoro-4-biphenylyl)propionic acid]

scientific article published on 01 January 1990

1H and 19F-nmr spectroscopic studies on the metabolism and urinary excretion of mono- and disubstituted phenols in the rat

scientific article published on 01 March 1996

1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat

article

1H-NMR spectroscopy as a means of monitoring nephrotoxicity as exemplified by studies with cephaloridine

scientific article published on January 1, 1992

750 MHz HPLC−NMR Spectroscopic Studies on the Separation and Characterization of the Positional Isomers of the Glucuronides of 6,11-Dihydro-11- oxodibenz[b,e]oxepin-2-acetic Acid

scientific article published on 01 January 1996

A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity

scientific article published on 07 September 2015

A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity

scientific article

A novel LC-MS approach for the detection of metabolites in DMPK studies.

scientific article published on October 2010

A perspective on the standards describing mass spectrometry-based metabolic phenotyping (metabolomics/metabonomics) studies in publications

scientific article published in 2021

Addressing the challenge of limited sample volumes inin vitrostudies with capillary-scale microfluidic LC–MS/MS

article

Age and microenvironment outweigh genetic influence on the Zucker rat microbiome

scientific article (publication date: 2014)

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

scientific article published on 01 November 2000

An investigation of the effects of carbon loading and endcapping on the solid-phase extraction of beta-blockers onto C18 bonded silica gel

scientific article published on 01 August 1993

An investigation of the properties of a "shielded" phase for the solid phase extraction of acidic and basic compounds

scientific article published on 01 February 1996

Application of 1H NMR spectroscopy to the metabolic phenotyping of rodent brain extracts: A metabonomic study of gut microbial influence on host brain metabolism.

scientific article published on 31 May 2017

Application of Directly Coupled HPLC-NMR-MS/MS to the Identification of Metabolites of 5-Trifluoromethylpyridone (2-Hydroxy-5-trifluoromethylpyridine) in Hydroponically Grown Plants

article

Application of NMR-based metabolomics to the investigation of salt stress in maize (Zea mays).

scientific article

Application of turbulent flow chromatography to the metabonomic analysis of human plasma: comparison with protein precipitation.

scientific article

Assessment of the Feasibility of the Use of Conductive Polymers in the Fabrication of Ion Mobility Spectrometers ⬇️

scientific article published on March 8, 2011

Asymptomatic 5-oxoprolinuria detected by proton magnetic resonance spectroscopy

scientific article published on 01 June 1993

Bioanalysis of p-trifluoromethylmandelic acid and Mosher's acid by chiral gas chromatography and fluorine nuclear magnetic resonance to study chiral inversion: application to rat urine samples ⬇️

scientific article published on 01 August 1997

Combined HPLC, NMR Spectroscopy, and Ion-Trap Mass Spectrometry with Application to the Detection and Characterization of Xenobiotic and Endogenous Metabolites in Human Urine

article

Comparison of high-performance liquid chromatography and gas chromatography for the analysis of ecdysteroids

scientific article published on 01 June 1980

Comparison of the properties of polymeric and C8 based materials for solid phase extraction

scientific article published on 01 September 1998

Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites

scientific article published on 01 October 1993

Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy.

scientific article

Determination of penicillamine and other thiols by combined high-performance liquid chromatography and post-column reaction with Ellman's reagent: application to human urine ⬇️

scientific article published on December 11, 1981

Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC-MS and ion mobility enabled HILIC-MS

article

Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions

article

Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry

scientific article published on 06 February 2013

Diclofenac metabolism in the mouse: Novelin vivometabolites identified by high performance liquid chromatography coupled to linear ion trap mass spectrometry ⬇️

scientific article published on September 28, 2011

Differential effect of troglitazone on the human bile acid transporters, MRP2 and BSEP, in the PXB hepatic chimeric mouse.

scientific article

Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine

article

Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat

article

Effect of Carbon Loading on the Extraction Properties of C-18 Bonded Silica Used for Solid-Phase Extraction of Acidic and Basic Analytes ⬇️

scientific article published on 01 August 1997

Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity ⬇️

scientific article published on 01 May 1998

Endogenous and xenobiotic metabolite profiling of liver extracts from SCID and chimeric humanized mice following repeated oral administration of troglitazone.

scientific article published on 18 December 2013

Flow injection spectroscopic analysis of model drugs using on-line UV-diode array, FT-infrared and 1H-nuclear magnetic resonance spectroscopy and time-of-flight mass spectrometry

scientific article published on 01 May 2000

Global Metabolite Profiling of Human Colorectal Cancer Xenografts in Mice Using HPLC–MS/MS ⬇️

scientific article published on May 22, 2013

Global metabolic profiling procedures for urine using UPLC–MS

article

HILIC-UPLC-MS for Exploratory Urinary Metabolic Profiling in Toxicological Studies

article

Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation

scientific article published on 23 January 2008

High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat

article

High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS)-Based Drug Metabolite Profiling ⬇️

scientific article published on 01 January 2011

High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver Failure.

scientific article published on 7 February 2017

High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline

scientific article published on 01 February 2000

High-performance liquid chromatography coupled to high-field proton nuclear magnetic resonance spectroscopy: application to the urinary metabolites of ibuprofen

scientific article published on 01 February 1993

Hippurate: the natural history of a mammalian-microbial cometabolite.

scientific article

Identification and quantification of glutathione adducts of clozapine using ultra-high-performance liquid chromatography with orthogonal acceleration time-of-flight mass spectrometry and inductively coupled plasma mass spectrometry

scientific article published on 01 July 2011

Identification and quantification of metabolites of 2,3,5,6-tetrafluoro-4-trifluoromethylaniline in rat urine using 19F nuclear magnetic resonance spectroscopy, high-performance liquid chromatography–nuclear magnetic resonance spectroscopy and high

scientific article published on 01 October 2000

Immobilized phenylboronic acids for the selective extraction of beta-blocking drugs from aqueous solution and plasma

scientific article published on 01 April 1993

Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra

scientific article published on 01 March 1994

In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs.

scientific article published on 31 May 2012

Induction of 5-oxoprolinuria in the rat following chronic feeding with N -acetyl 4-aminophenol (paracetamol)

scientific article published on 01 September 1993

Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides.

scientific article published in January 2010

Investigation of the human metabolism of antipyrine using coupled liquid chromatography and nuclear magnetic resonance spectroscopy of urine

scientific article published on 01 August 1993

Investigation of the metabolism of 14C/13C-practolol in rat using directly coupled radio-HPLC-NMR-MS

Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection.

scientific article published on 19 June 2017

Ion-Pairing Chromatography and Amine Derivatization Provide Complementary Approaches for the Targeted LC-MS Analysis of the Polar Metabolome

scientific article published in 2022

Ion-pair reversed-phase thin-layer chromatography of basic drugs using sulphonic acids ⬇️

scientific article published on June 10, 1988

Is Current Practice Adhering to Guidelines Proposed for Metabolite Identification in LC-MS Untargeted Metabolomics? A Meta-Analysis of the Literature

scientific article published in 2021

Kinetic modelling of acyl glucuronide and glucoside reactivity and development of structure-property relationships

scientific article published on 01 February 2020

Liquid chromatography coupled with high-field proton NMR for profiling human urine for endogenous compounds and drug metabolites

scientific article published on 01 August 1992

Liquid chromatography–mass spectrometry based global metabolite profiling: A review ⬇️

scientific article published on November 4, 2011

Managing the challenge of chemically reactive metabolites in drug development.

scientific article published on April 2011

Measurement of Internal Acyl Migration Reaction Kinetics Using Directly Coupled HPLC−NMR: Application for the Positional Isomers of Synthetic (2-Fluorobenzoyl)-d-glucopyranuronic Acid ⬇️

scientific article published on August 1, 1996

Metabolic Hydrolysis of Aromatic Amides in Selected Rat, Minipig, and Human In Vitro Systems

scientific article

Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat

scientific article published in 2020

Metabolite Profiles from Dried Blood Spots for Metabonomic Studies Using UPLC Combined with Orthogonal Acceleration TOF-MS: Effects of Different Papers and Sample Storage Stability ⬇️

scientific article published on December 1, 2011

Metabolite profiles from dried biofluid spots for metabonomic studies using UPLC combined with oaToF-MS.

scientific article published in June 2010

Metabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects

scientific article published on 01 November 2004

NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man

article

NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues

scientific article published on 18 October 2007

NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat

scientific article published on 01 November 1997

NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases

scientific article published on 01 January 1991

Nuclear Magnetic Resonance and High-Performance Liquid Chromatography-Nuclear Magnetic Resonance Studies on the Toxicity and Metabolism of Ifosfamide

article

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

scientific article published on 06 March 2018

Pharmacometabonomics as an effector for personalized medicine.

scientific article published on January 2011

Proton magnetic resonance spectroscopy of human urine: Excretion of 1-(3'-carboxypropyl)-3,7-dimethylxanthine by man after dosing with oxpentifylline.

scientific article published in January 1987

Proton nuclear magnetic resonance of urine and bile from paracetamol dosed rats

scientific article published on 01 January 1990

Quantitative structure-metabolism relationships for substituted benzoic acids in the rabbit: prediction of urinary excretion of glycine and glucuronide conjugates

scientific article published on 01 February 1996

Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies

scientific article published in November 1992

Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLCNMR-MS

scientific article published on 01 January 1999

Rapid Determination of the Pharmacokinetics and Metabolic Fate of Gefitinib in the Mouse Using a Combination of UPLC/MS/MS, UPLC/QToF/MS and Ion Mobility (IM)-Enabled UPLC/QToF/MS

scientific article published on 07 December 2020

Rapid profiling method for the analysis of lipids in human plasma using ion mobility enabled-reversed phase-ultra high performance liquid chromatography/mass spectrometry

scientific article published on 04 October 2019

Reversed-phase high-performance liquid chromatography combined with on-line UV diode array, FT infrared, and 1H nuclear magnetic resonance spectroscopy and time-of-flight mass spectrometry: application to a mixture of nonsteroidal antiinflammatory d

scientific article published on 01 August 2000

Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development

scientific article published on 11 November 2010

Sensitive and Reproducible Mass Spectrometry-Compatible RP-UHPLC Analysis of Tricarboxylic Acid Cycle and Related Metabolites in Biological Fluids: Application to Human Urine

scientific article published on 08 December 2020

Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine.

scientific article published in January 1988

Species differences in the metabolism of 14C-p-trifluoromethylaniline: production of an oxanilic acid as the major metabolite by the rat

scientific article published in 1985

Stability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation

scientific article

Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice

scientific article published on October 2006

Studies on the metabolism of 4-fluoroaniline and 4-fluoroacetanilide in rat: formation of 4-acetamidophenol (paracetamol) and its metabolites via defluorination and N-acetylation

Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy

scientific article published on 01 January 1990

Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides

scientific article published on 08 December 2010

The analysis of acetaminophen (paracetamol) and seven metabolites in rat, pig and human plasma by U(H)PLC-MS

scientific article published on 28 April 2020

The hepatic reductase null mouse as a model for exploring hepatic conjugation of xenobiotics: application to the metabolism of diclofenac.

scientific article published on 28 September 2011

The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse

scientific article published on 10 December 2013

The metabolic fate of fenclozic acid in chimeric mice with a humanized liver

scholarly article by Anja Ekdahl et al published September 2018 in Archives of Toxicology

The metabolism and excretion of [14C] 2- and 4-chlorobenzoic acids in the rat

scientific article published on 01 July 2000

The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice

scientific article published on 02 May 2018

Troglitazone metabolism and transporter effects in chimeric mice: a comparison between chimeric humanized and chimeric murinized FRG mice.

scientific article published on 13 January 2014

UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat.

scientific article published in July 2010

Use of an Atmospheric Solids Analysis Probe (ASAP) for High Throughput Screening of Biological Fluids: Preliminary Applications on Urine and Bile

article

Variation in Antibiotic-Induced Microbial Recolonization Impacts on the Host Metabolic Phenotypes of Rats

scientific article published on 29 June 2011

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