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List of works by Heikki Rauvala

30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane

scientific journal article

AMIGO is an auxiliary subunit of the Kv2.1 potassium channel

scientific journal article

AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats

scientific article

Action of Clostridium perfringens neuraminidase on gangliosides GM1 and GM2 above and below the critical micelle concentration of substrate ⬇️

scientific article published on June 1, 1976

Activation of Human Umbilical Vein Endothelial Cells Leads to Relocation and Release of High-Mobility Group Box Chromosomal Protein 1

article

Activation of NMDA receptors promotes dendritic spine development through MMP-mediated ICAM-5 cleavage.

scientific article published on 6 August 2007

Activity blockade increases the number of functional synapses in the hippocampus of newborn rats

scientific article published in January 2003

Activity-induced enhancement of HB-GAM expression in rat hippocampal slices

scientific article

Acute brain trauma in mice followed by longitudinal two-photon imaging

scientific article published on 6 April 2014

Adhesive membrane protein of rat brain enhances neurite outgrowth of neuroblastoma cells.

scientific article published in January 1985

Alkali-stable blood group A- and B-active poly(glycosyl)-peptides from human erythrocyte membrane

scientific article published on May 1978

Amigo adhesion protein regulates development of neural circuits in zebrafish brain

scientific article

Amphoterin as an extracellular regulator of cell motility: from discovery to disease.

scientific article published on March 2004

Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation

scientific article

An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors

scientific article published on October 1989

Articular cartilage degradation and de-differentiation of chondrocytes by the systemic administration of retinyl acetate-ectopic production of osteoblast stimulating factor-1 by chondrocytes in mice

scientific article published in December 2002

Association of cortactin with dynamic actin in lamellipodia and on endosomal vesicles.

scientific article published on December 2000

Axonal amphoterin mRNA is regulated by translational control and enhances axon outgrowth

scientific article

Behavioral alterations induced by repeated testing in C57BL/6J and 129S2/Sv mice: implications for phenotyping screens

scientific article published in February 2004

Behavioural phenotypes of hypomorphic KCC2-deficient mice

scientific journal article

Binding of laminin to brain gangliosides and inhibition of laminin-neuron interaction by the gangliosides

scientific article published on 01 June 1987

CD73 is a major regulator of adenosinergic signalling in mouse brain.

scientific article

Cell adhesion mediated by a purified fucosyltransferase.

scientific article published on July 1983

Circulating levels of a soluble form of receptor for advanced glycation end products and high-mobility group box chromosomal protein 1 in patients with acute pancreatitis

scientific article published on 01 November 2009

Co-expression of heparin-binding growth-associated molecule (HB-GAM) and N-syndecan (syndecan-3) in developing rat brain

scientific article

Cognitive deficit and development of motor impairment in a mouse model of Niemann-Pick type C disease

scientific article published in April 2002

Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

scientific article published on 01 December 2000

Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth

scientific article

Crystal structure and role of glycans and dimerization in folding of neuronal leucine-rich repeat protein AMIGO-1

scientific article

Determination (by methylation analysis) of the substitution pattern of 2-amino-2-deoxyhexitols obtained from O-glycosylic carbohydrate units of glycoproteins

scientific article published in September 1977

Developmentally regulated neurite outgrowth response from dorsal root ganglion neurons to heparin-binding growth-associated molecule (HB-GAM) and the expression of HB-GAM in the targets of the developing dorsal root ganglion neurites.

scientific article published in August 1996

Differential expression and biological activity of the heparin-binding growth-associated molecule (HB-GAM) in lung cancer cell lines

scientific article published on 01 November 1997

Disialosyl paragloboside. A novel ganglioside isolated from human kidney

scientific article published on 01 December 1978

Distinct expression of type XIII collagen in neuronal structures and other tissues during mouse development

scientific journal article

Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice

scientific article published on 9 July 2010

Effect of heparin-binding growth-associated molecule (HB-GAM) on synaptic transmission and early LTP in rat hippocampal slices

scientific journal article

Effects of targeted overexpression of pleiotrophin on postnatal bone development

scientific journal article

Efferent targets of osseous CGRP-immunoreactive nerve fiber before and after bone destruction in adjuvant arthritic rat: an ultramorphological study on their terminal-target relations

scientific article published on 01 July 1997

Enhanced hippocampal GABAergic inhibition in mice overexpressing heparin-binding growth-associated molecule

scientific article published on 13 February 2006

Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule.

scientific article published in June 2001

Enhancement of neurite outgrowth by laminin and by heparin-binding proteins of brain.

scientific article published in February 1988

Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration.

scientific article published on September 2004

Evaluation of social and physical enrichment in modulation of behavioural phenotype in C57BL/6J female mice

scientific article

Exposure of major neutral glycolipids in red cells to galactose oxidase. Effect of neuraminidase

scientific article published on 01 June 1986

Expression of GluK1c underlies the developmental switch in presynaptic kainate receptor function

scientific article published on 12 March 2012

Expression of HB-GAM (heparin-binding growth-associated molecules) in the pathways of developing axonal processes in vivo and neurite outgrowth in vitro induced by HB-GAM

scientific journal article

Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis.

scientific article published on January 1995

Extracellular adhesive molecules in neurite growth.

scientific article published on February 1989

Fast network oscillations in the newborn rat hippocampus in vitro

scientific article published on 01 February 2000

Flat-floored air-lifted platform: a new method for combining behavior with microscopy or electrophysiology on awake freely moving rodents.

scientific article

Gangliosides of brain and of extraneural tissues: structural relationship to protein-linked glycans

scientific article published on January 1980

Gangliosides of human kidney ⬇️

scientific article published on December 10, 1976

Glycolipid accumulation in bronchoalveolar space in adult respiratory distress syndrome

scientific article published on 01 November 1984

HB-GAM (heparin-binding growth-associated molecule) and heparin-type glycans in the development and plasticity of neuron-target contacts

scientific article

HB-GAM inhibits proliferation and enhances differentiation of neural stem cells

scientific article

HB-GAM is a cytokine present in Alzheimer's and Down's syndrome lesions.

scientific article published in January 1996

HB-GAM/Pleiotrophin and Midkine are differently expressed and distributed during retinoic acid-induced neural differentiation of P19 cells

scientific article published on September 2003

HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator

scientific article published on 24 May 2011

HMGB1 contributes to regeneration after spinal cord injury in adult zebrafish

scientific article published on 31 August 2013

Heparan sulfate proteoglycan syndecan-3 is a novel receptor for GDNF, neurturin, and artemin

scientific article

Heparan sulphate and HB-GAM (heparin-binding growth-associated molecule) in the development of the thalamocortical pathway of rat brain

scientific journal article

Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons

scientific article

Heparin-binding growth-associated molecule contains two heparin-binding beta -sheet domains that are homologous to the thrombospondin type I repeat

scientific article published on 01 May 2000

Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility.

scientific article

High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule

scientific article

High mobility group 1 B-box mediates activation of human endothelium

scientific article published in October 2003

High mobility group box 1 protein as a marker of hepatocellular injury in human liver transplantation

scientific article published in October 2008

High mobility group box 1 protein induction by Mycobacterium bovis BCG.

scientific article published on January 2007

High mobility group box-1 (HMGB1; amphoterin) is required for zebrafish brain development.

scientific article published on 28 April 2011

High-frequency synaptic stimulation induces association of fyn and c-src to distinct phosphorylated components

scientific article published on 01 April 2000

High-mannose structure of apolipoprotein-B from low-density lipoproteins of human plasma

scientific article published in 1985

Hyperexcretion of free N-acetylneuraminic acid--a novel type of sialuria

scientific article published on 01 February 1985

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

scientific article (publication date: 30 May 1997)

Immunocytochemical localization of the heparin-binding growth-associated molecule (HB-GAM) in the developing and adult rat cerebellar cortex

scientific journal article

Impaired behavioural flexibility and memory in mice lacking GDNF family receptor alpha2.

scientific article published on July 2004

Increased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds

scientific article published on January 2004

Induction of heparin-binding growth-associated molecule expression in reactive astrocytes following hippocampal neuronal injury

scientific article

Inhibition and enhancement of neural regeneration by chondroitin sulfate proteoglycans.

scientific article

Interaction of fimbriae of Haemophilus influenzae type B with heparin-binding extracellular matrix proteins

scientific article published on October 2000

Intercellular adhesion molecule-5 induces dendritic outgrowth by homophilic adhesion

scientific article

Interview with Dr. Heikki Rauvala regarding pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin). Interview by Marco E Bianchi

scientific article

Introduction: HMGB1 in inflammation and innate immunity

scientific article published on 01 October 2011

Isolation and partial characterization of human kidney gangliosides ⬇️

scientific article published on February 23, 1976

Isolation and some characteristics of an adhesive factor of brain that enhances neurite outgrowth in central neurons

scientific article

Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3)

scientific article

JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination.

scientific article

Long-term individual housing in C57BL/6J and DBA/2 mice: assessment of behavioral consequences

scientific article published in June 2005

Mass spectrometric sequence study of the oligosaccharide of human transferrin

scientific article published on 01 October 1978

Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A.

scientific article published in August 2003

Methylation analysis of neuraminic acids by gas chromatography-mass spectrometry

scientific article

Methylation techniques in the structural analysis of glycoproteins and glycolipids

scientific article published on January 1981

Mice deficient in transmembrane prostatic acid phosphatase display increased GABAergic transmission and neurological alterations.

scientific article

Molecular nature of the blood-group ABH antigens of the human erythrocyte membrane

scientific article published on 01 November 1980

Monomer-Micelle Transition of the Ganglioside GM1 and the Hydrolysis by Clostridium perfringens Neuraminidase ⬇️

scientific article published on July 1, 1979

N -Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth

scientific article

N-syndecan and HB-GAM (heparin-binding growth-associated molecule) associate with early axonal tracts in the rat brain

scientific journal article

Neurite growth-promoting protein (amphoterin, p30) binds syndecan

scientific article published on 01 June 1992

Neurite outgrowth in brain neurons induced by heparin-binding growth-associated molecule (HB-GAM) depends on the specific interaction of HB-GAM with heparan sulfate at the cell surface

scientific article

Neurite outgrowth of neuroblastoma cells induced by proteins covalently coupled to glass coverslips

scientific article published on 01 September 1984

Neurite outgrowth of neuroblastoma cells: dependence on adhesion surface--cell surface interactions

scientific article published on March 1984

Neuronal regulation of immune responses in the central nervous system

scientific article published on 12 January 2009

Neurotrophic growth factors in the development and plasticity of nervous system

scientific article published in January 1999

Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3Fuc2nLc6)

scientific article published on 01 August 1984

Occurrence of amphoterin (HMG1) as an endogenous protein of human platelets that is exported to the cell surface upon platelet activation

scientific article published on 01 December 2000

Occurrence of disialosyl groups in glycoproteins

scientific article published in January 1977

Osteoblast recruitment and bone formation enhanced by cell matrix-associated heparin-binding growth-associated molecule (HB-GAM).

scientific article published on November 1998

Osteocyte-derived HB-GAM (pleiotrophin) is associated with bone formation and mechanical loading

scientific article

Overexpression of VEGF in testis and epididymis causes infertility in transgenic mice: evidence for nonendothelial targets for VEGF.

scientific article

Persistent elevation of high mobility group box-1 protein (HMGB1) in patients with severe sepsis and septic shock*

scientific article published on 01 March 2005

Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors.

scientific article

Pivotal advance: analysis of proinflammatory activity of highly purified eukaryotic recombinant HMGB1 (amphoterin).

scientific article published on 15 September 2006

RAGE-mediated cell signaling.

scientific article published on January 2013

Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation

scientific article published on 7 August 2002

Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways

scientific article

Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells

scientific article

Reg1ulatory role and molecular interactions of a cell-surface heparan sulfate proteoglycan (N-syndecan) in hippocampal long-term potentiation.

scientific article published in February 1999

Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.

scientific article

Regulation of cell migration by amphoterin.

scientific article published in February 2000

Regulation of mRNA localization by transmembrane signalling: local interaction of HB-GAM (heparin-binding growth-associated molecule) with the cell surface localizes beta-actin mRNA

scientific article

Regulation of monocyte migration by amphoterin (HMGB1).

scientific article published on 6 May 2004

Retarded growth and deficits in the enteric and parasympathetic nervous system in mice lacking GFR alpha2, a functional neurturin receptor.

scientific article published on February 1999

Reversible Disruption of Neuronal Mitochondria by Ischemic and Traumatic Injury Revealed by Quantitative Two-Photon Imaging in the Neocortex of Anesthetized Mice

scientific article

Role of HB-GAM (heparin-binding growth-associated molecule) in proliferation arrest in cells of the developing rat limb and its expression in the differentiating neuromuscular system

scientific journal article

Role of heparin-binding growth-associated molecule (HB-GAM) in hippocampal LTP and spatial learning revealed by studies on overexpressing and knockout mice

scientific article (publication date: June 2002)

Secretion and biological activities of heparin-binding growth-associated molecule. Neurite outgrowth-promoting and mitogenic actions of the recombinant and tissue-derived protein

scientific article

Sensory neurons from N-syndecan-deficient mice are defective in survival

scientific article published on September 2008

Shedded neuronal ICAM-5 suppresses T-cell activation

scientific article published on 25 January 2008

Solubilization of proteins in dimethyl sulfoxide by permethylation: application to structural studies of apolipoprotein B

scientific article published in 1985

Solution structures of the first and fourth TSR domains of F-spondin

scientific article published on 01 August 2006

Strain and gender differences in the behavior of mouse lines commonly used in transgenic studies

scientific article published in January 2001

Structural similarity of the terminal carbohydrate sequences of glycoproteins and glycolipids

scientific article published on January 1979

Studies on cell adhesion and recognition. I. Extent and specificity of cell adhesion triggered by carbohydrate-reactive proteins (glycosidases and lectins) and by fibronectin.

scientific article

Studies on cell adhesion and recognition. II. The kinetics of cell adhesion and cell spreading on surfaces coated with carbohydrate-reactive proteins (glycosidases and lectins) and fibronectin.

scientific article

Sulfoglycolipids bind to adhesive protein amphoterin (P30) in the nervous system

scientific article

Syndecan-3-deficient mice exhibit enhanced LTP and impaired hippocampus-dependent memory

scientific article

The O75X adhesin of uropathogenic Escherichia coli is a type IV collagen-binding protein

scientific article published on 01 March 1989

The O75X adhesin of uropathogenic Escherichia coli: receptor-active domains in the canine urinary tract and in-vitro interaction with laminin

scientific article

The Poly(glycosyl) Chains of Glycoproteins.. Characterisation of a Novel Type of Glycoprotein Saccharides from Human Erythrocyte Membrane

scientific article published on 01 December 1978

The adhesive and neurite-promoting molecule p30: analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons

scientific article published on December 1988

The disialosyl group of glycoproteins. Occurrence in different tissues and cellular membranes

scientific article published in July 1977

The fucoganglioside of human kidney ⬇️

scientific article published on February 15, 1976

The layered fold of the TSR domain of P. falciparum TRAP contains a heparin binding site

scientific article published on July 2006

The mechanisms of growth and regeneration of axons

scientific article published in January 1990

The receptor for advanced glycation end products mediates the chemotaxis of rabbit smooth muscle cells

scientific article published on 01 March 1997

The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction.

scientific article published on September 1998

The role of an agrin-growth factor interaction in ACh receptor clustering

scientific article published on 01 January 1996

The role of heparin-binding growth-associated molecule (HB-GAM) in the postsynaptic induction in cultured muscle cells

scientific journal article

The structural basis of the different affinities of two types of acidic N-glycosidic glycopeptides for concanavalin A--sepharose

scientific article published on November 1976

The two thrombospondin type I repeat domains of HB-GAM display a cooperative function in N-syndecan binding and regulation of synaptic plasticity.

scientific article published on 29 March 2006

The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons

scientific article

The tyrosine hydroxylase 2 (TH2) system in zebrafish brain and stress activation of hypothalamic cells.

scientific article published on 16 July 2014

Transgenic expression of syndecan-1 uncovers a physiological control of feeding behavior by syndecan-3.

scientific article published in July 2001

Transgenic mice overexpressing the full-length neurotrophin receptor trkB exhibit increased activation of the trkB-PLCgamma pathway, reduced anxiety, and facilitated learning

scientific article

Transient disruption of spermatogenesis by deregulated expression of neurturin in testis

scientific article

Ultrastructural Localization of β-Actin and Amphoterin mRNA in Cultured Cells: Application of Tyramide Signal Amplification and Comparison of Detection Methods

scientific article published in 1999

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

scientific article (publication date: 2004)

[The dynamic synapse]

scientific article published on 01 January 2003

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