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List of works by Dominik A. Megger

A Family of Hydrazone-Based Nucleosides for Use in Metal-Mediated Base Pairs

A metal-mediated base pair that discriminates between the canonical pyrimidine nucleobases

scientific article published on 12 October 2016

A structured proteomic approach identifies 14-3-3Sigma as a novel and reliable protein biomarker in panel based differential diagnostics of liver tumors

scientific article published on 5 November 2014

Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

scientific article

Allergy-Protective Arabinogalactan Modulates Human Dendritic Cells via C-Type Lectins and Inhibition of NF-κB.

scientific article published on 8 January 2016

Analysis of disease-associated protein expression using quantitative proteomics—fibulin-5 is expressed in association with hepatic fibrosis.

scientific article published on 6 April 2015

BioInfra.Prot: A comprehensive proteomics workflow including data standardization, protein inference, expression analysis and data publication.

scientific article

Broad and potent antiviral activity of the NAE inhibitor MLN4924.

scientific article published on February 2016

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology

scientific article published on 30 March 2020

Comparison of label-free and label-based strategies for proteome analysis of hepatoma cell lines.

scientific article published on 14 August 2013

Conformational change induced by metal-ion-binding to DNA containing the artificial 1,2,4-triazole nucleoside

scientific article

Contiguous Metal-Mediated Base Pairs Comprising Two AgI Ions

Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression

scientific article published on 14 September 2017

Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing.

scientific article published on 7 October 2015

Efficient Synthesis of 1-Deaza-6-methoxypurine-N9-β-2′-deoxyribonucleoside and Related DNA Building Blocks

Eukaryotic elongation factor 2 is a prognostic marker and its kinase a potential therapeutic target in HCC.

scientific article published on 02 January 2017

Hepatic expression of proteasome subunit alpha type-6 is upregulated during viral hepatitis and putatively regulates the expression of ISG15 ubiquitin-like modifier, a proviral host gene in hepatitis C virus infection.

scientific article published on February 2016

Identification of novel biomarker candidates for the immunohistochemical diagnosis of cholangiocellular carcinoma.

scientific article

Identification of proteins that mediate the pro-viral functions of the interferon stimulated gene 15 in hepatitis C virus replication

scientific article published on December 2013

Identification of the Consistently Altered Metabolic Targets in Human Hepatocellular Carcinoma.

scientific article

Immunohistochemical Markers Distinguishing Cholangiocellular Carcinoma (CCC) from Pancreatic Ductal Adenocarcinoma (PDAC) Discovered by Proteomic Analysis of Microdissected Cells

scientific article published on 7 December 2015

Interaction of Pt(II) and Pd(II) complexes of terpyridine with 1-methylazoles: A combined experimental and density functional study

Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes

scientific article published on 03 January 2019

Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line

scientific article published on 27 February 2017

Metal-mediated base pairs in nucleic acids with purine- and pyrimidine-derived nucleosides

scientific article published on January 2012

Mixed guanine, adenine base quartets: possible roles of protons and metal ions in their stabilization

scientific article

NHS-based Tandem Mass Tagging of Proteins at the Level of Whole Cells: A Critical Evaluation in Comparison to Conventional TMT-Labeling Approaches for Quantitative Proteome Analysis

scientific article published in January 2017

One Sample, One Shot - Evaluation of sample preparation protocols for the mass spectrometric proteome analysis of human bile fluid without extensive fractionation.

scientific article published on 05 December 2016

Proteome Analyses of Hepatocellular Carcinoma

scientific article published on 15 March 2014

Proteome Analysis of a Hepatocyte-Specific BIRC5 (Survivin)-Knockout Mouse Model during Liver Regeneration

article

Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study.

scientific article

Quantitative Secretome Analysis of Activated Jurkat Cells Using Click Chemistry-Based Enrichment of Secreted Glycoproteins

scientific article published on 03 October 2016

Quantitative Tissue Proteomics Analysis Reveals Versican as Potential Biomarker for Early-Stage Hepatocellular Carcinoma

scientific article published on 2 December 2015

Quantitative proteome analysis reveals the correlation between endocytosis-associated proteins and hepatocellular carcinoma dedifferentiation.

scientific article published on 9 August 2016

Silver(I) and Mercury(II) Complexes with 1-Methyl-1,2,4-triazole as Models for Metal-Mediated Base Pairs - Formation of Discrete Complexes in Solution vs. One- and Two-Dimensional Coordination Polymers in the Solid State

Silver(I)-mediated Hoogsteen-type base pairs.

scientific article published on 31 July 2011

Silver(I)-mediated cytosine self-pairing is preferred over hoogsteen-type base pairs with the artificial nucleobase 1,3-dideaza-6-nitropurine

scientific article published in January 2010

Structurally related hydrazone-based metal complexes with different antitumor activities variably induce apoptotic cell death

scientific article

Systematic analysis of synergistic proteome modulations in a drug combination of cisplatin and MLN4924

scientific article published on 01 December 2018

The Canonical Immediate Early 3 Gene Product pIE611 of Mouse Cytomegalovirus Is Dispensable for Viral Replication but Mediates Transcriptional and Posttranscriptional Regulation of Viral Gene Products

scientific article published on 10 June 2015

Tissue-based quantitative proteome analysis of human hepatocellular carcinoma using tandem mass tags.

scientific article published on 28 July 2016

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