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List of works by Gisli Jenkins

A big beautiful wall against infection

scientific article

A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis

scientific article published on 20 March 2014

A systematic review of Anakinra, Tocilizumab, Sarilumab and Siltuximab for coronavirus-related infections

scientific article published on 27 April 2020

Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.

scientific article published on 14 June 2016

Adjustment for index event bias in genome-wide association studies of subsequent events

article

Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

scientific article

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

scientific article (publication date: August 2016)

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis.

scientific article published on May 2017

An integrin-targeted non-viral vector for pulmonary gene therapy

scientific article published in March 2000

Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation

scientific article published on 9 June 2014

Biophysical characterization of an integrin-targeted non-viral vector

scientific article published in January 2003

Bronchoalveolar Lavage is Safe and Well Tolerated in Individuals with Idiopathic Pulmonary Fibrosis: An Analysis of the PROFILE Study

scientific article published on 28 August 2020

Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

scientific article published on 24 February 2016

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

scientific article published on 14 July 2021

Climate change and lung health: presidential failure, professional responsibility

scientific article published on 21 April 2019

Climate change and lung health: the challenge for a new president

scientific article published on 19 January 2017

Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice

scientific article

Cyclooxygenase-2 overexpression, using an integrin-targeted gene delivery system (the LID vector), inhibits fibroblast proliferation in vitro and leads to increased prostaglandin E(2) in the lung.

scientific article published in March 2002

Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis

scientific article published in 2024

ECM Crosslinking Enhances Fibroblast Growth and Protects Against Matrix Proteolysis in Lung Fibrosis.

scientific article

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.

scientific article published in February 2004

Embracing social media

scientific article

Endotyping idiopathic pulmonary fibrosis should improve outcomes for all patients with progressive fibrotic lung disease

scientific article published on 19 November 2014

First year of the thoracic triumvirate

scientific article published in July 2016

Formation of LID vector complexes in water alters physicochemical properties and enhances pulmonary gene expression in vivo

scientific article published in June 2003

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

scientific article published on 20 October 2017

IPF: Moving from Idiopathic to Infectious Pulmonary Fibrosis?

scientific article published on July 2017

Identification of a missense variant in SPDL1 associated with idiopathic pulmonary fibrosis

scientific article published on 23 March 2021

In search of the fibrotic epithelial cell: opportunities for a collaborative network.

scientific article published on 15 June 2011

Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation

scientific article

Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma

scientific article published on 24 October 2011

Interplay Between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

scientific article published on 20 October 2017

Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma

scientific article published on 28 October 2015

Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

scientific article

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

scientific article published on 12 March 2015

Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33-mediated macrophage polarization and emphysema

scientific article published on 25 October 2016

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

scientific article published on 15 January 2009

Mapping the future for pulmonary fibrosis: report from the 17th International Colloquium on Lung and Airway Fibrosis

scientific article

Methods for the Assessment of Active Transforming Growth Factor-β in Cells and Tissues.

scientific article

Molecular Endotyping of Pulmonary Fibrosis

scientific article published on 10 September 2015

Novel approaches to pulmonary fibrosis

scientific article

Outcome of Hospitalization for COVID-19 in Patients with Interstitial Lung Disease: An International Multicenter Study

scientific article published on 02 October 2020

Pirfenidone should be prescribed for patients with idiopathic pulmonary fibrosis

scientific article published on 05 March 2013

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis

scientific article published on 28 October 2013

Preprint servers: a 'rush to publish' or 'just in time delivery' for science?

scientific article published on 20 April 2020

Presence of a prothrombotic state in people with idiopathic pulmonary fibrosis: a population-based case-control study.

scientific article published on 3 September 2013

Proportion of Idiopathic Pulmonary Fibrosis Risk Explained by Known Common Genetic Loci in European Populations

scientific article published on 23 November 2020

Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land?

scientific article published on January 1, 2003

Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6 Expression

scientific article published on 9 February 2016

Reducing affinity of αvβ8 interactions with latent TGFβ: dialling down fibrosis.

scientific article published on May 2015

Reply to: Hospitalization Outcomes for COVID-19 in Patients with Interstitial Lung Disease; a Potential Role for Aerodigestive Pathophysiology?

scientific article published on 20 November 2020

Repression of IP-10 by interactions between histone deacetylation and hypermethylation in idiopathic pulmonary fibrosis

scientific article published on 19 April 2010

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post–COVID-19 Study

scientific article published in 2023

Respiratory follow-up of patients with COVID-19 pneumonia

scientific article published on 24 August 2020

Review of the British Thoracic Society Winter Meeting 2016, 7-9 December, London, UK.

scientific article published on 4 May 2017

Review of the British Thoracic Society Winter Meeting 2017, 6-8 December 2017, London, UK

scientific article published on 14 June 2018

Review of the British Thoracic Society Winter Meeting 2018, 5-7 December 2018, London, UK

scientific article published on 05 August 2019

Role of integrin-mediated TGFbeta activation in the pathogenesis of pulmonary fibrosis

scientific article published on August 2009

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

scientific article published on 14 March 2016

Severity of lung injury in cyclooxygenase-2-deficient mice is dependent on reduced prostaglandin E(2) production.

scientific article

Sphingosine-1-phosphate metabolism: can its enigmatic lyase promote the autophagy of fibrosis?

scientific article published on 3 November 2015

Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis

scientific article published on 15 January 2016

Study the past to divine the future. Confucius' wisdom doesn't work for idiopathic pulmonary fibrosis

scientific article

TGF-β Activation and Lung Fibrosis

scientific article published on 01 July 2012

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.

scientific article published on 19 May 2016

The British Thoracic Society survey of rehabilitation to support recovery of the Post Covid -19 population.

scientific article published on 12 May 2020

The first thoracic triumvirate

scientific article published in October 2015

The pathogenesis of idiopathic pulmonary fibrosis.

scientific article published on 15 October 2010

The rising incidence of idiopathic pulmonary fibrosis in the U.K

scientific article (publication date: June 2011)

To Suppress the Radicals We Must Have Biomarkers of Oxidative Stress

scientific article published in April 2016

Transforming Growth Factor-Beta Promotes Rhinovirus Replication in Bronchial Epithelial Cells by Suppressing the Innate Immune Response ⬇️

scientific article published on September 6, 2012

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

scientific article published on 16 September 2020

Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

scientific article

αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease

scientific article

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