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List of works by Serena Di Cosimo

18F-FDG PET/CT for early prediction of response to neoadjuvant lapatinib, trastuzumab, and their combination in HER2-positive breast cancer: results from Neo-ALTTO.

scientific article

A phase I pharmacokinetic and pharmacodynamic study of dalotuzumab (MK-0646), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors.

scientific article

A phase II study on metastatic breast cancer patients treated with weekly vinorelbine with or without trastuzumab according to HER2 expression: changing the natural history of HER2-positive disease

scientific article published on 12 January 2006

Addition of either lonidamine or granulocyte colony-stimulating factor does not improve survival in early breast cancer patients treated with high-dose epirubicin and cyclophosphamide

scientific article published in September 2003

Adjuvant Lapatinib and Trastuzumab for Early Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Results From the Randomized Phase III Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization Trial

scientific article

Advancing immunotherapy for early-stage triple-negative breast cancer

scientific article published on 18 September 2020

Adverse events risk associated with bevacizumab addition to breast cancer chemotherapy: a meta-analysis

scientific article published on 01 July 2019

Alopecia in a premenopausal breast cancer woman treated with letrozole and triptorelin

scientific article published in November 2003

An RB-1 loss of function gene signature as a tool to predict response to neoadjuvant chemotherapy plus anti-HER2 agents: a substudy of the NeoALTTO trial (BIG 1-06)

scientific article published on 11 December 2019

Automated breast ultrasound compared to hand-held ultrasound in surveillance after breast-conserving surgery

scientific article published on 18 June 2020

Axillary coverage by whole breast irradiation in 1 to 2 positive sentinel lymph nodes in breast cancer patients.

scientific article published on 16 March 2016

Axillary nodal involvement by primary tumor features in early breast cancer: an analysis of 2600 patients

scientific article published on 01 August 2019

Better Together: Targeted Combination Therapies in Breast Cancer

scientific article

Body mass index and clinical benefit of fulvestrant in postmenopausal women with advanced breast cancer

scientific article published on 10 May 2016

Brain metastases in HER2-positive breast cancer: challenges and opportunities.

scientific article published in October 2012

Breast and ovarian metastatic localization of signet-ring cell gastric carcinoma

scientific article published on 01 May 2003

Can colorectal cancer patients with thymidylate synthase-overexpressing liver metastases have an overall survival advantage with hepatic arterial infusion alone?

scientific article published in September 2003

Cardiac biomarkers for early detection and prediction of trastuzumab and/or lapatinib-induced cardiotoxicity in patients with HER2-positive early-stage breast cancer: a NeoALTTO sub-study (BIG 1-06).

scientific article published on 27 December 2017

Circulating Tumor DNA in HER2-Amplified Breast Cancer: A Translational Research Substudy of the NeoALTTO Phase III Trial

scientific article published on 12 March 2019

Circulating tumor cells and response to neoadjuvant paclitaxel and HER2-targeted therapy: a sub-study from the NeoALTTO phase III trial

scientific article

Clinical Evaluation of the Use of Exemestane as Further Hormonal Therapy after Nonsteroidal Aromatase Inhibitors in Postmenopausal Metastatic Breast Cancer Patients

scientific article published on 01 March 2007

Clinical outcome of HER2-positive breast cancer patients after failure on adjuvant trastuzumab: the potential of the time to relapse

scientific article

Combination of the mTOR inhibitor ridaforolimus and the anti-IGF1R monoclonal antibody dalotuzumab: preclinical characterization and phase I clinical trial

scientific article published on 15 October 2014

Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting.

scientific article

Complete remission in metastatic breast cancer: expecting the unexpected-results of a cross-sectional study

scientific article published on 05 January 2017

Controversies in breast cancer: the mammalian target of rapamycin as a target for breast cancer therapy

scientific article

Correction: Article on TLC-D99, Paclitaxel, Trastuzumab in HER-2 Breast Cancer

Did Circulating Tumor Cells Tell us all they Could? The Missed Circulating Tumor Cell Message in Breast Cancer

scientific article published on 11 November 2015

Discontinuation of hormone therapy for elderly breast cancer patients after hypofractionated whole-breast radiotherapy

scientific article published on 16 June 2018

Disease progression pattern in metastatic breast cancer patients treated with anti-HER2 therapies

scientific article published on 21 January 2015

Disease-free interval in metastatic breast cancer patients undergoing complete remission: implications of cross-sectional study design and biologic considerations about disease history.

scientific article

Do HER-2 positive metastatic breast cancer patients benefit from the use of trastuzumab beyond disease progression? A mono-institutional experience and systematic review of observational studies

scientific article published on May 2008

Docetaxel in advanced gastric cancer--review of the main clinical trials.

scientific article published on January 2003

Does granulocyte colony-stimulating factor worsen anemia in early breast cancer patients treated with epirubicin and cyclophosphamide?

scientific article published on 12 June 2006

Does the concurrent use of anthracycline and granulocyte colony-stimulating factor influence the risk of secondary leukaemia in breast cancer women?

scientific article published on 27 April 2005

Dynamics of the hazard for distant metastases after ipsilateral breast tumor recurrence according to estrogen receptor status: An analysis of 2851 patients

scientific article published on 14 May 2018

Early immune modulation by single-agent trastuzumab as a marker of trastuzumab benefit

scientific article published on 27 November 2018

Effect of filgrastim on serum lactate dehydrogenase and alkaline phosphatase values in early breast cancer patients

scientific article published in January 2004

Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer.

scientific article published on April 2007

Factors associated with surgical management following neoadjuvant therapy in patients with primary HER2-positive breast cancer: results from the NeoALTTO phase III trial

scientific article published on 7 April 2013

Factors influencing acute and late toxicity in the era of adjuvant hypofractionated breast radiotherapy.

scientific article published on 28 July 2016

Fatal thrombocytopenia and thrombocytopathia: an unusual onset of non-small cell lung cancer.

scientific article

Fixed dose-rate gemcitabine infusion as first-line treatment for advanced-stage carcinoma of the pancreas and biliary tree

scientific article published in September 2005

Gastric stump lymphoma five years after distal gastrectomy.

scientific article

Gemcitabine-induced atrial fibrillation: a hitherto unreported manifestation of drug toxicity

scientific article published in April 2000

HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature.

scientific article published on 9 December 2016

HER2/neu expression and hormonal therapy in early breast cancer: can muddy waters become clear?

scientific article published in February 2004

Heart to heart with trastuzumab: a review on cardiac toxicity.

scientific article

High consistency between characteristics of primary intraductal breast cancer and subtype of subsequent ipsilateral invasive cancer

scientific article published on 26 August 2019

How to study and overcome tumor heterogeneity with circulating biomarkers: The breast cancer case

scientific article

Human epidermal growth factor receptor 2 (HER2)-positive and hormone receptor-positive breast cancer: new insights into molecular interactions and clinical implications.

scientific article published on August 2013

Hypofractionated Whole-Breast Irradiation With or Without Boost in Elderly Patients: Clinical Evaluation of an Italian Experience

scientific article published on 22 April 2018

Hypofractionated irradiation in 794 elderly breast cancer patients: An observational study

scientific article published on 25 August 2019

Impact of Diabetes, Insulin, and Metformin Use on the Outcome of Patients With Human Epidermal Growth Factor Receptor 2-Positive Primary Breast Cancer: Analysis From the ALTTO Phase III Randomized Trial.

scientific article published on 13 March 2017

Impact of five prophylactic filgrastim schedules on hematologic toxicity in early breast cancer patients treated with epirubicin and cyclophosphamide

scientific article

Implication of breast cancer phenotype for patients with leptomeningeal carcinomatosis

scientific article

Incidence of chemotherapy-induced amenorrhea depending on the timing of treatment by menstrual cycle phase in women with early breast cancer

scientific article

Innovative therapy, monoclonal antibodies, and beyond: Highlights from the eighth annual meeting

scientific article published on 30 October 2018

International Expert Consensus on Primary Systemic Therapy in the Management of Early Breast Cancer: Highlights of the Fifth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2013).

scientific article published on May 2015

International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010).

scientific article published on January 2011

Interobserver variability (between radiation oncologist and radiation therapist) in tumor bed contouring after breast-conserving surgery

scientific article published on 27 March 2019

Is anthracycline-based chemotherapy alone adequate for young women with estrogen receptor-positive breast cancer?

scientific article published on 29 August 2005

Is there a benefit by the sequence anastrozole-formestane for postmenopausal metastatic breast cancer women?

scientific article published in July 2003

Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial

scientific article

Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response

scientific article published on 14 August 2014

Management of breast cancer with targeted agents: importance of heterogeneity. [corrected].

scientific article published on 02 February 2010

Management of the axilla in early breast cancer patients in the genomic era.

scientific article

Midazolam for acute emesis refractory to dexamethasone and granisetron after highly emetogenic chemotherapy: a phase II study

scientific article published on 25 January 2005

Modeling anti-IL-6 therapy using breast cancer patient-derived xenografts.

scientific article published on September 2016

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

scientific article

Neoadjuvant Chemotherapy Exerts Selection Pressure Towards Luminal Phenotype Breast Cancer.

scientific article published on 12 December 2017

Neoadjuvant eribulin mesylate following anthracycline and taxane in triple negative breast cancer: Results from the HOPE study

scientific article published on 07 August 2019

Neoadjuvant treatment of HER2 and hormone-receptor positive breast cancer - moving beyond pathological complete response.

scientific article published on 04 January 2014

New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials

scientific article

Nonpegylated Liposomal Doxorubicin (TLC-D99), Paclitaxel, and Trastuzumab in HER-2-Overexpressing Breast Cancer: A Multicenter Phase I/II Study

scientific article published on 01 January 2009

Overview of diagnostic/targeted treatment combinations in personalized medicine for breast cancer patients.

scientific article published on 16 December 2013

Pathological complete response in breast cancer patients receiving neoadjuvant chemotherapy

scientific article published on 28 June 2014

Pattern of rash, diarrhea, and hepatic toxicities secondary to lapatinib and their association with age and response to neoadjuvant therapy: analysis from the NeoALTTO trial

scientific article published on 18 November 2013

Phosphoinositide 3-Kinase Mutations in Breast Cancer: A "Good" Activating Mutation?

scientific article published on 11 August 2009

Pilot study of celecoxib and infusional 5-fluorouracil as second-line treatment for advanced pancreatic carcinoma

scientific article

Plasma miRNA Levels for Predicting Therapeutic Response to Neoadjuvant Treatment in HER2-positive Breast Cancer: Results from the NeoALTTO Trial

scientific article published on 27 February 2019

Platinum salts in advanced breast cancer: a systematic review and meta-analysis of randomized clinical trials.

scientific article

Pregnancies during and after trastuzumab and/or lapatinib in patients with human epidermal growth factor receptor 2-positive early breast cancer: analysis from the NeoALTTO (BIG 1-06) and ALTTO (BIG 2-06) trials

scientific article published on 18 October 2018

Prognosis of women with early breast cancer and PIK3CA mutations.

scientific article

RE: Presence of Circulating Tumor Cells in High-Risk Early Breast Cancer During Follow-Up and Prognosis

scientific article published on 01 November 2019

RNA Sequencing to Predict Response to Neoadjuvant Anti-HER2 Therapy: A Secondary Analysis of the NeoALTTO Randomized Clinical Trial.

scientific article published on 29 September 2016

Radiotherapy with the anti-programmed cell death ligand-1 immune checkpoint blocker avelumab: acute toxicities in triple-negative breast cancer

scientific article published on 15 November 2018

Re: Time to Adjuvant Chemotherapy for Breast Cancer in National Comprehensive Cancer Network Institutions

scientific article published on 11 November 2013

Role of patient and tumor characteristics in sentinel lymph node metastasis in patients with luminal early breast cancer: an observational study.

scientific article published on 3 February 2016

Réponse de D. Torrejon, J. Cortes, D. Serpico, S. Di Cosimo à l’article de F. Vasseur et al. : KI67 chez les patientes jeunes présentant un cancer du sein. Gynecol Obstet Fertil 2013; 41(1):16-9

scientific article published on 04 June 2013

SOLTI NeoPARP: a phase II randomized study of two schedules of iniparib plus paclitaxel versus paclitaxel alone as neoadjuvant therapy in patients with triple-negative breast cancer

scientific article

Second- and third-generation aromatase inhibitors as first-line endocrine therapy in postmenopausal metastatic breast cancer patients: a pooled analysis of the randomised trials.

scientific article published on 30 May 2006

Subacute motor weakness and left renal mass

scientific article published on 01 June 2003

Survival outcomes of the NeoALTTO study (BIG 1-06): updated results of a randomised multicenter phase III neoadjuvant clinical trial in patients with HER2-positive primary breast cancer

scientific article published on 01 August 2019

Suspected Pharmacological Interactions in a Cancer Patient During Methadone Maintenance

scholarly article by Gianluigi Ferretti et al published June 2004 in Addictive Disorders and Their Treatment

Targeted therapies in breast cancer: where are we now?

scientific article

Targeted therapy-induced diarrhea: A review of the literature.

scientific article published on 05 December 2013

Ten-year results of applying an original scoring system for addressing adjuvant therapy use after breast-conserving surgery for ductal carcinoma in situ of the breast.

scientific article published on 23 June 2017

The 41-gene classifier TRAR predicts response of HER2 positive breast cancer patients in the NeoALTTO study

scientific article published on 05 July 2019

The use of breast imaging for predicting response to neoadjuvant lapatinib, trastuzumab and their combination in HER2-positive breast cancer: Results from Neo-ALTTO.

scientific article published on 8 December 2017

Trastuzumab Emtansine Plus Non-Pegylated Liposomal Doxorubicin in HER2-Positive Metastatic Breast Cancer (Thelma): A Single-Arm, Multicenter, Phase Ib Trial

scientific article published on 25 November 2020

Trastuzumab and Hypofractionated Whole Breast Radiotherapy: A Victorious Combination?

scientific article published on 24 August 2017

Trastuzumab cardiac toxicity: a problem we put our heart into

scientific article published on 03 August 2015

Trastuzumab-related cardiotoxicity in the elderly: a role for cardiovascular risk factors

scientific article published on 09 August 2011

Trastuzumab-related cardiotoxicity in the elderly: a role for cardiovascular risk factors

scientific article published on 01 July 2019

Vinorelbine With Capecitabine, an Evergreen Doublet for Advanced Breast Cancer: A Systematic Literature Review and Pooled-Analysis of Phase II-III Studies

scientific article

Waiting for Godot: Predictive factors for adjuvant treatment of patients with luminal breast cancer

scientific article

Whole-transcriptome analysis links trastuzumab sensitivity of breast tumors to both HER2 dependence and immune cell infiltration

scientific article

Zoledronic-acid-induced circulating level modifications of angiogenic factors, metalloproteinases and proinflammatory cytokines in metastatic breast cancer patients

scientific article published on 2 August 2005

microRNAs in breast cancer development and treatment.

scientific article

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