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List of works by R Pujol-Borrell

A Novel Splice Site Mutation in the SERPING1 Gene Leads to Haploinsufficiency by Complete Degradation of the Mutant Allele mRNA in a Case of Familial Hereditary Angioedema

article

A SNP in intron 1 of TSHR controls its thymic expression and susceptibility to Graves’ disease suggesting central tolerance failure in pathogenesis.

scientific article published on 23 November 2011

A one-tube polymerase chain reaction protocol demonstrates CC chemokine overexpression in Graves' disease glands

scientific article published on 01 August 1999

A prospective study of lymphocyte subpopulations and regulatory T cells in patients with chronic hepatitis C virus infection developing interferon-induced thyroiditis

scientific article published in October 2011

ADVANTAGES OF USING A CELL SEPARATOR AND METRIZAMIDE GRADIENTS FOR HUMAN ISLET PURIFICATION1

scientific article published in June 1996

AIRE genetic variants and predisposition to polygenic autoimmune disease: The case of Graves' disease and a systematic literature review

scientific article published on 4 June 2016

AU-differential display, reproducibility of a differential mRNA display targeted to AU motifs

scientific article published in January 2003

Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: relevance for autoimmunity

scientific article published on 01 November 1983

Adhesion molecules in human islet beta-cells. De novo induction of ICAM-1 but not LFA-3.

scientific article published on November 1991

Analysis of the PD-1/PD-L1 axis in human autoimmune thyroid disease: Insights into pathogenesis and clues to immunotherapy associated thyroid autoimmunity

scientific article published on 08 June 2019

Analysis of the cumulative changes in Graves' disease thyroid glands points to IFN signature, plasmacytoid DCs and alternatively activated macrophages as chronicity determining factors.

scientific article published on 26 February 2011

Anti-peripherin B lymphocytes are positively selected during diabetogenesis

scientific article published on 23 April 2008

Asialoagalactothyroglobulin binds to the surface of human thyroid cells at a site distinct from the 'microsomal' autoantigen

scientific article published on 01 April 1984

Association of an SNP with intrathymic transcription of TSHR and Graves' disease: a role for defective thymic tolerance.

scientific article published on 3 June 2011

Autoimmune Predisposition in Down Syndrome May Result from a Partial Central Tolerance Failure due to Insufficient Intrathymic Expression ofAIREand Peripheral Antigens

scientific article published on 12 September 2014

Autoimmune polyendocrinopathies. Pathogenic hypotheses

scientific article published on January 1986

Beta-cell function abnormalities in islets from an adult subject with nesidioblastosis and autoantibodies against the islet cells

scientific article published on January 1997

CCL4L Polymorphisms and CCL4/CCL4L Serum Levels Are Associated with Psoriasis Severity

scientific article published in September 2011

CCL4L polymorphisms and serum levels are associated with psoriasis severity

scientific article published on 25 November 2010

Capture of cell-derived microvesicles (exosomes and apoptotic bodies) by human plasmacytoid dendritic cells

scientific article published on 08 February 2012

Central T cell tolerance: Identification of tissue-restricted autoantigens in the thymus HLA-DR peptidome.

scientific article

Central Tolerance Mechanisms to TSHR in Graves' Disease: Contributions to Understand the Genetic Association

scientific article published on 05 November 2018

Characterisation of the NES2Y cell line and its use in the production of human glucose-responsive insulin producing (hGRIP) cell lines by cell-cell fusion

scientific article

Characterization of neural cell adhesion molecule (NCAM) expression in thyroid follicular cells: induction by cytokines and over-expression in autoimmune glands

scientific article published on 01 December 1994

Characterization of patients with anti-modified citrullinated vimentin antibodies (MCVA).

scientific article published on 23 November 2011

Characterization of recent thymic emigrants (RTEs), transitional B and Th17 cells in multiple sclerosis (MS).

scientific article published on 23 November 2011

Chemokines determine local lymphoneogenesis and a reduction of circulating CXCR4+ T and CCR7 B and T lymphocytes in thyroid autoimmune diseases.

scientific article

Clinical and structural impact of mutations affecting the residue Phe367 of FOXP3 in patients with IPEX syndrome.

scientific article

Clinical laboratory standard capillary protein electrophoresis alerted of a low C3 state and lead to the identification of a Factor I deficiency due to a novel homozygous mutation.

scientific article published on 14 April 2016

Comparative study of clinical grade human tolerogenic dendritic cells

scientific article published on 9 June 2011

Composition of the HLA-DR-associated human thymus peptidome.

scientific article published on 12 July 2013

Copy number variation in the CCL4L gene is associated with susceptibility to acute rejection in lung transplantation

article

Correlation between residual beta-cell function and islet cell antibodies in newly diagnosed type I diabetes. Follow-up study

scientific article published on November 1989

Cytotoxic effect of IFN-gamma plus TNF-alpha on human islet cells

scientific article published on 01 April 1991

De novo HLA class II and enhanced HLA class I molecule expression in SV40 transfected human thyroid epithelial cells.

scientific article published on June 1991

Decreased AIRE and promiscuous gene expression in thymus from Down syndrome individuals may explain predisposition to autoimmunity.

scientific article

Deficiency of the autoimmune regulator AIRE in thymomas is insufficient to elicit autoimmune polyendocrinopathy syndrome type 1 (APS-1)

scientific article published on 01 April 2007

Dendritic cells pulsed with antigen-specific apoptotic bodies prevent experimental type 1 diabetes

scientific article

Detection of thyroid growth immunoglobulins (TGI) by [3H]-thymidine incorporation in cultured rat thyroid follicles

scientific article published on 01 November 1983

Determinación of islet-cell antibodies in different groups of diabetics (author's transl)

scientific article published on January 1979

Determination of islet cell antibodies by immunofluorescence

scientific article published on 01 December 1982

Development of a new HLA-DRB real-time PCR typing method.

scientific article published in January 2005

Diagnostic value of different anti-citrullinated peptides antibodies in rheumatoid arthritis

scientific article published on 23 November 2011

Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus.

scientific article published in April 2004

Differential effects of monophosphoryl lipid A and cytokine cocktail as maturation stimuli of immunogenic and tolerogenic dendritic cells for immunotherapy

scientific article published on 12 November 2011

Differential expression and regulation of MHC products in the endocrine and exocrine cells of the human pancreas

scientific article published on 01 July 1986

Differential expression and regulation of major histocompatibility complex (MHC) products in neural and glial cells of the human fetal brain

scientific article

Distinct pattern of peripheral lymphocyte subsets in Graves' disease with persistency of anti-TSHR autoantibodies

scientific article published on 31 July 2019

ENDOTOXIN CONTAMINATION MAY BE RESPONSIBLE FOR THE UNEXPLAINED FAILURE OF HUMAN PANCREATIC ISLET TRANSPLANTATION1

scientific article published in March 1998

Effects of a short prednisone regime at clinical onset of type 1 diabetes

scientific article published in April 1993

Efferocytosis promotes suppressive effects on dendritic cells through prostaglandin E2 production in the context of autoimmunity.

scientific article

Efficacy of low-dose subcutaneous interleukin-2 to treat advanced human immunodeficiency virus type 1 in persons with </=250/microL CD4 T cells and undetectable plasma virus load

scientific article published in July 1999

Endotoxin activity of collagenase and human islet transplantation

scientific article published in August 1997

Engraftment of islets obtained by collagenase and Liberase in diabetic rats: a comparative study

scientific article published in November 2001

Enhancement of thyrocyte HLA class II expression by thyroid stimulating hormone

scientific article published on 01 September 1987

Epithelial MHC class II sub-region expression in autoimmunity

scientific article

Epithelial expression of HLA class II molecules: a new pathogenic factor in organ-specific autoimmunity

scientific article published on January 1987

Evaluation of splenic function by dynamic gammagraphy, study of pitted erythrocytes and submembranous vacuoles in patients with slight and severe splenic trauma receiving conservative treatment or splenectomy

scientific article published in February 2007

Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cells

scientific article published in August 2003

Expression and function of the IL-2 receptor in activated human plasmacytoid dendritic cells

scientific article published on 01 July 2007

Expression of glutamic acid decarboxylase (GAD) in the α, β and δ cells of normal and diabetic pancreas: implications for the pathogenesis of type I diabetes

scientific article published on 28 June 2008

Expression of intercellular adhesion molecule-1 in thyroid follicular cells in autoimmune, non-autoimmune and neoplastic diseases of the thyroid gland: discordance with HLA.

scientific article published in February 1992

Gamma delta lymphocytes in endocrine autoimmunity: evidence of expansion in Graves' disease but not in type 1 diabetes

scientific article published on 01 May 1993

Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes.

scientific article published on 11 November 2009

Gene expression signature of tolerance and lymphocyte subsets in stable renal transplants: results of a cross-sectional study.

scientific article

Genetics of Graves' Disease: Special Focus on the Role of TSHR Gene.

scientific article published on 11 September 2015

Global gene expression changes in type 1 diabetes: insights into autoimmune response in the target organ and in the periphery.

scientific article published on 11 August 2010

Graves' disease TSHR-stimulating antibodies (TSAbs) induce the activation of immature thymocytes: a clue to the riddle of TSAbs generation?

scientific article published on 23 March 2015

Growth inhibition of human endothelial cells by human recombinant tumor necrosis factor alpha and interferon-gamma

scientific article published on 01 August 1994

HLA DR, DP, DQ induction in human islet beta cells by the cytokine combination IFN-gamma + TNF-alpha

scientific article published on 01 January 1990

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

scientific article published in Nature

HLA-B27 genotyping by fluorescent resonance emission transfer (FRET) probes in real-time PCR.

scientific article published on August 2004

HLA-D subregion expression by thyroid epithelium in autoimmune thyroid diseases and induced in vitro

scientific article published on 01 September 1987

HLA-D/DR expression on epithelial cells: the finger on the trigger?

scientific article published on 01 January 1986

HLA-DM and invariant chain are expressed by thyroid follicular cells, enabling the expression of compact DR molecules

scientific article published in February 1999

HLA-DQ2/DQ8 and HLA-DQB1*02 homozygosity typing by real-time polymerase chain reaction for the assessment of celiac disease genetic risk: evaluation of a Spanish celiac population.

scientific article published in December 2014

High prevalence of subclinical Sjögren's syndrome features in patients with autoimmune thyroid disease

scientific article published on 01 September 1997

Human intestinal alphabeta IEL clones in celiac disease show reduced IL-10 synthesis and enhanced IL-2 production

scientific article published on 01 November 2006

Human pancreatic islet function at the onset of type 1 (insulin-dependent) diabetes mellitus

scientific article published on 01 April 1993

Hyperexpression of transporter in antigen processing-1 (TAP-1) in thyroid glands affected by autoimmunity: a contributory factor to the breach of tolerance to thyroid antigens? ⬇️

scientific article published on July 1, 1997

Hyperinducibility of HLA class II expression of thyroid follicular cells from Graves' disease. A primary defect?

scientific article published in April 1995

Hypotheses on genetic contributions to the aetiology of diabetes mellitus

scientific article published on 01 August 1984

Hypotheses on the etiology of insulin-dependent diabetes: published and recent ideas

scientific article published on January 1985

IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice

scientific article published in December 2004

Identification and characterization of a novel splice site mutation in the SERPING1 gene in a family with hereditary angioedema.

scientific article published on 4 December 2013

Identification of a KRAB-containing zinc finger protein, ZNF304, by AU-motif-directed display method and initial characterization in lymphocyte activation

scientific article published in May 2002

Immunological senescence and thymic function in transplantation.

scientific article published on August 2009

Immunopathology of insulin-dependent diabetes. New hypothesis

scientific article published on April 1986

In vitro and in vivo reversal of thyroid epithelial polarity: its relevance for autoimmune thyroid disease

scientific article published on 01 September 1984

In vitro inhibition of insulin release mediated by sera with complement-fixing islet cell antibodies belonging to normal first degree relatives of patients with type 1 diabetes

scientific article

Inappropriate HLA class II expression on epithelial cells: new insight in the pathogenesis of distinctive autoimmunity

scientific article published on January 1986

Inappropriate major histocompatibility complex class II expression by thyroid follicular cells in thyroid autoimmune disease and by pancreatic beta cells in type I diabetes

scientific article published on April 1986

Induction of intercellular adhesion molecule-1 but not of lymphocyte function-associated antigen-3 in thyroid follicular cells

scientific article published on February 1992

Influence of tumor necrosis factor-alpha on the modulation by interferon-gamma of HLA class II molecules in human thyroid cells and its effect on interferon-gamma binding

scientific article published on 01 August 1989

Influx of recent thymic emigrants into autoimmune thyroid disease glands in humans

scientific article published on 11 July 2008

Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus

scientific article published on 24 October 2005

Interferon expression in the pancreases of patients with type I diabetes

scientific article published on 01 June 1995

Interferon-gamma induces HLA-DR expression by thyroid epithelium

scientific article published on 01 August 1985

Islet cell surface antibodies in type 1 (insulin-dependent) diabetes mellitus: use of human fetal pancreas cultures as substrate

scientific article published on 01 February 1982

Islet transplantation in seminal vesicles restores glycemia in diabetic rats: a preliminary study

scientific article published in February 2002

Islet-cell antibodies in Spanish diabetics

scientific article published on 01 July 1978

Islet-cell antibody determination: the essential message

scientific article published on 01 March 1983

Islet-infiltrating B-cells in nonobese diabetic mice predominantly target nervous system elements

scientific article published in January 2005

Lectin-induced expression of DR antigen on human cultured follicular thyroid cells

scientific article published in Nature

Ligation of Notch Receptors in Human Conventional and Plasmacytoid Dendritic Cells Differentially Regulates Cytokine and Chemokine Secretion and Modulates Th Cell Polarization

scientific article published on 18 May 2011

Lymphoid neogenesis in chronic inflammatory diseases.

scientific article

Mechanisms of autoimmunity: relevance to the pathogenesis of type I (insulin-dependent) diabetes mellitus

scientific article published on October 1987

Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients

scientific article published on 01 May 2005

Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus

scientific article published in October 2002

Myelin peptides in multiple sclerosis.

scientific article published on 12 February 2009

Natural killer cells are required for accelerated type 1 diabetes driven by interferon-beta.

scientific article

New ideas in thyroid autoimmunity

scientific article published on January 1987

Novel Mutations Causing C5 Deficiency in Three North-African Families.

scientific article

Novel and atypical splicing mutation in a compound heterozygous UNC13D defect presenting in Familial Hemophagocytic Lymphohistiocytosis triggered by EBV infection

scientific article published on 10 May 2014

Occurrence of thyrocyte HLA class II expression in a wide variety of thyroid diseases: relationship with lymphocytic infiltration and thyroid autoantibodies

scientific article published on 01 February 1988

One-tube-PCR technique for CCL2, CCL3, CCL4 and CCL5 applied to fine needle aspiration biopsies shows different profiles in autoimmune and non-autoimmune thyroid disorders

scientific article published on 01 April 2006

Organ-specific autoimmunity: a 1986 overview

scientific article published on December 1986

Overexpression of metallothionein I/II: a new feature of thyroid follicular cells in Graves' disease.

scientific article

Pancreas in recent onset insulin-dependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile

scientific article published in August 1994

Pancreatic beta-cell damage. In search of novel pathogenetic factors.

scientific article published on November 1988

Peptides presented by HLA class I molecules in the human thymus.

scientific article published on 9 September 2013

Peripherin is a relevant neuroendocrine autoantigen recognized by islet-infiltrating B lymphocytes

scientific article published on May 2007

Phenotype and Functional Characteristics of Islet-Infiltrating B-Cells Suggest the Existence of Immune Regulatory Mechanisms in Islet Milieu

scientific article published on 01 April 2007

Population structure in copy number variation and SNPs in the CCL4L chemokine gene

scientific article published on 27 March 2008

Positive-hemocultured pneumonias

scientific article published on January 25, 1979

Post traumatic splenic function depending on severity of injury and management.

scientific article published on 2 February 2011

Predictive immunomonitoring — The COST ENTIRE initiative

scientific article published in April 2013

Presence of insulin autoantibodies at clinical diagnosis of diabetes mellitus type I predicts loss of beta cell function

scientific article published on 01 January 1988

Primary alloproliferative TH1 response induced by immature plasmacytoid dendritic cells in collaboration with myeloid DCs.

scientific article published on December 2005

Proteasome subunits, low‐molecular‐mass polypeptides 2 and 7 are hyperexpressed by target cells in autoimmune thyroid disease but not in insulin‐dependent diabetes mellitus: implications for autoimmunity ⬇️

scientific article (publication date: August 1997)

Pulmonary lesions in rheumatoid arthritis

scientific article published in December 1976

Puzzling diabetic transgenic mice: a lesson for human type 1 diabetes?

scientific article published on October 1988

Real-time PCR using fluorescent resonance emission transfer probes for HLA-B typing.

scientific article

Reassessing the role of HLA-DRB3 T-cell responses: evidence for significant expression and complementary antigen presentation.

scientific article

Reduced numbers of plasmacytoid dendritic cells in aged blood donors

scientific article published on 29 May 2007

Reevaluation of autoantibodies to islet cell membrane in IDDM. Failure to detect islet cell surface antibodies using human islet cells as substrate

scientific article published in December 1992

Reg (regenerating) gene overexpression in islets from non-obese diabetic mice with accelerated diabetes: role of IFNbeta.

scientific article published on 10 August 2006

Regenerating gene Iα is a biomarker for diagnosis and monitoring of celiac disease: a preliminary study

scientific article published in September 2011

Regulation of TSHR Expression in the Thyroid and Thymus May Contribute to TSHR Tolerance Failure in Graves' Disease Patients via Two Distinct Mechanisms

scientific article published on 18 July 2019

Regulatory T cells and other lymphocyte subpopulations in patients with melanoma developing interferon-induced thyroiditis during high-dose interferon-α2b treatment.

scientific article published in April 2013

Retrovirus-like sequences in Graves' disease: implications for human autoimmunity

scientific article published on 01 May 1989

Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity

scientific article published on 01 November 1983

Self-reactive cytotoxic gamma delta T lymphocytes in Graves' disease specifically recognize thyroid epithelial cells

scientific article

Serum protein electrophoresis and complement deficiencies: a veteran but very versatile test in clinical laboratories

scientific article published on 01 July 2019

Single-cell analysis of intrathyroidal lymphocytes shows differential cytokine expression in Hashimoto's and Graves' disease

scientific article published on 01 December 1997

Snake bite poisoning. Review of six cases (author's transl)

scientific article

Specific T-cell proliferation to myelin peptides in relapsing-remitting multiple sclerosis

scientific article published on 29 December 2010

Stable antigen-specific T-cell hyporesponsiveness induced by tolerogenic dendritic cells from multiple sclerosis patients

scientific article published on 01 March 2012

Statin-associated autoimmune myopathy: A distinct new IFL pattern can increase the rate of HMGCR antibody detection by clinical laboratories.

scientific article published on 15 September 2016

Syngeneic islet transplantation into seminal vesicles of diabetic rats

scientific article

TLR-activated conventional DCs promote γ-secretase-mediated conditioning of plasmacytoid DCs.

scientific article published on 24 April 2012

Tacrolimus treatment of plasmacytoid dendritic cells inhibits dinucleotide (CpG-)-induced tumour necrosis factor-alpha secretion

scientific article published on 24 August 2006

Th1 predominance and perforin expression in minor salivary glands from patients with primary Sjögren's syndrome

scientific article published on 01 August 1999

The chemokine network. I. How the genomic organization of chemokines contains clues for deciphering their functional complexity. ⬇️

scientific article published on May 2007

Thyrocyte HLA class II expression and regulation in relation to thyroid autoimmunity

scientific article published on 01 January 1987

Thyroglobulin peptides associate in vivo to HLA-DR in autoimmune thyroid glands

scientific article published in July 2008

Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers

scientific article published on September 2001

Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens

scientific article published on 01 December 1998

Transfection with SV40 gene of human pancreatic endocrine cells

scientific article published on June 1991

Why are pancreatic beta cells destroyed?

scientific article published on January 15, 1983

[A change in the expression of histocompatibility antigens could lead to autoimmunity]

scientific article published on 01 April 1984

[Anti-ribosome antibodies (immunofluorescence) associated with chronic active hepatitis]

scientific article published on 01 May 1981

[Autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura preceding a mixed connective tissue disease]

scientific article published on 01 September 1983

[Insulin-dependent diabetes mellitus: subcutaneous insulin therapy with a portable infusion pump]

scientific article published on 01 March 1983

[Islet cell antibodies in diabetes mellitus (author's transl)]

scientific article published on 01 March 1980

[Islet cell antibodies in diabetic patients with other autoimmune diseases (author's transl)]

scientific article published on 01 September 1981

[Modulation of the expression of histocompatibility antigens in thyroid follicular cells and in the beta cells of the pancreas: implications in the pathogenesis of thyroid autoimmune diseases and type 1 diabetes mellitus]

scientific article published on 01 November 1986

[New contributions to the etiology of insulin-dependent diabetes (author's transl)]

scientific article published on 01 February 1980

[Osteomalacia as the principal manifestation of celiac disease]

scientific article published on 01 December 1983

[Thymus: old gland, new ideas]

scientific article published on 01 February 2003

[Toward the standardization of pancreatic islet cell antibodies]

scientific article published on 01 November 1986

[Usual presentation of Hodgkin's disease]

scientific article published on 01 March 1978

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