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List of works by Silvia Gregori

A 1alpha,25-dihydroxyvitamin D(3) analog enhances regulatory T-cells and arrests autoimmune diabetes in NOD mice

scientific article published in May 2002

A peptide binding motif for I-Eg7, the MHC class II molecule that protects E alpha-transgenic nonobese diabetic mice from autoimmune diabetes

scientific article published on 01 June 1999

APVO210: A Bispecific Anti-CD86-IL-10 Fusion Protein (ADAPTIR™) to Induce Antigen-Specific T Regulatory Type 1 Cells.

scientific article published on 25 May 2018

Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells

scientific article published on 11 June 2008

An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells.

scientific article

Antitumorigenic and antiinsulinogenic effects of calcitriol on insulinoma cells and solid beta-cell tumors

scientific article published on October 2002

Association of HLA-G 3' untranslated region variants with type 1 diabetes mellitus

scientific article

Association of genetic variants in the 3'UTR of HLA-G with Recurrent Pregnancy Loss.

scientific article published on 28 June 2016

BAT2 and BAT3 polymorphisms as novel genetic risk factors for rejection after HLA-related SCT

scientific article

CD4+ T-regulatory cells: toward therapy for human diseases.

scientific article published on June 2008

CD4+ regulatory T cells: mechanisms of induction and effector function.

scientific article

Clinical Outlook for Type-1 and FOXP3(+) T Regulatory Cell-Based Therapy

scientific article

Clinical tolerance in allogeneic hematopoietic stem cell transplantation ⬇️

scientific article published on May 1, 2011

Coexpression of CD163 and CD141 identifies human circulating IL-10-producing dendritic cells (DC-10)

scientific article published on 06 March 2019

Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

scientific article

Correlation of Der p 2 T-cell responses with clinical characteristics of children allergic to house dust mite

article

Corrigendum: Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses.

scientific article published on 22 February 2018

Cross-reactive mycobacterial and self hsp60 epitope recognition in I-A(g7) expressing NOD, NOD-asp and Biozzi AB/H mice

scientific article published on March 2002

DHRS9 is a Stable Marker of Human Regulatory Macrophages

scientific article

Dendritic cells a double-edge sword in autoimmune responses ⬇️

scientific article published on 02 August 2012

Dendritic cells in networks of immunological tolerance.

scientific article published on February 2011

Deviation of pancreas-infiltrating cells to Th2 by interleukin-12 antagonist administration inhibits autoimmune diabetes

scientific article published on 01 September 1997

Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells

scientific article

Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway

scientific article

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

article by Nathan R. Martinez et al published 1 May 2003 in Journal of Clinical Investigation

Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development

scientific article published on 01 October 2003

Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes

scientific article published on 01 December 2000

Editorial: HLA-G-Mediated Immune Tolerance: Past and New Outlooks

scientific article published on 27 December 2016

Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells.

scientific article

Engineered T Regulatory Type 1 Cells for Clinical Application.

scientific article published on 15 February 2018

Erratum: Corrigendum: Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells

Functional type 1 regulatory T cells develop regardless of FOXP3 mutations in patients with IPEX syndrome.

scientific article published on 14 March 2011

Genotypes and haplotypes in the 3' untranslated region of the HLA-G gene and their association with clinical outcome of hematopoietic stem cell transplantation for beta-thalassemia

scientific article

Graft-versus-leukemia effect of HLA-haploidentical central-memory T-cells expanded with leukemic APCs and modified with a suicide gene

scientific article

Granulocyte-colony stimulating factor drives the in vitro differentiation of human dendritic cells that induce anergy in naïve T cells

scientific article

HIV-1-derived lentiviral vectors directly activate plasmacytoid dendritic cells, which in turn induce the maturation of myeloid dendritic cells.

scientific article

HIV-1-mediated insertional activation of STAT5B and BACH2 trigger viral reservoir in T regulatory cells.

scientific article published on 8 September 2017

HIV-derived vectors for gene therapy targeting dendritic cells.

scientific article

HLA-G Orchestrates the Early Interaction of Human Trophoblasts with the Maternal Niche.

scientific article

HLA-G expressing DC-10 and CD4(+) T cells accumulate in human decidua during pregnancy

scientific article published on 10 December 2012

HLA-G expression levels influence the tolerogenic activity of human DC-10.

scientific article published on 6 February 2015

HLA-G expression on blasts and tolerogenic cells in patients affected by acute myeloid leukemia

scientific article published on 13 March 2014

Human tolerogenic DC-10: perspectives for clinical applications.

scientific article published on 28 September 2012

Hurdles in therapy with regulatory T cells

scientific article published on September 2015

IL-10-Engineered Human CD4(+) Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism.

scientific article published on 5 July 2017

IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma

scientific article published in June 2003

IL-12 administration reveals diabetogenic T cells in genetically resistant I-Ealpha-transgenic nonobese diabetic mice: resistance to autoimmune diabetes is associated with binding of Ealpha-derived peptides to the I-A(g7) molecule

scientific article published in October 2001

Immune depletion with cellular mobilization imparts immunoregulation and reverses autoimmune diabetes in nonobese diabetic mice

scientific article published on 23 July 2009

Immunological Outcome in Haploidentical-HSC Transplanted Patients Treated with IL-10-Anergized Donor T Cells

scientific article published on 31 January 2014

Impact of HLA-G polymorphism on the outcome of allogeneic hematopoietic stem cell transplantation for metastatic renal cell carcinoma

scientific article published on 13 November 2017

Induction of anergic allergen-specific suppressor T cells using tolerogenic dendritic cells derived from children with allergies to house dust mites.

scientific article published on 11 February 2010

Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells

scientific article published in June 2006

Induction of transplantation tolerance by 1,25-dihydroxyvitamin D(3).

scientific article

Interleukin-10-Producing DC-10 Is a Unique Tool to Promote Tolerance Via Antigen-Specific T Regulatory Type 1 Cells.

scientific article

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans.

scientific article

Is FOXP3 a bona fide marker for human regulatory T cells?

scientific article published on April 2008

Isolation, expansion, and characterization of human natural and adaptive regulatory T cells

scientific article published on January 2007

Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells.

scientific article published on 13 May 2011

Methods for in vitro generation of human type 1 regulatory T cells

scientific article published in January 2011

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization

scientific article published in January 2017

Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies

scientific article

Mixed chimerism evolution is associated with T regulatory type 1 (Tr1) cells in a β-thalassemic patient after haploidentical haematopoietic stem cell transplantation

scientific article published on 9 December 2015

Modulation of immune responses in lentiviral vector-mediated gene transfer

scientific article published on 27 April 2018

Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy.

scientific article published on 16 August 2010

Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses

scientific article published on 21 December 2017

Monoclonal antibodies against recombinant human growth hormone as probes to study immune function

scientific article published on 01 June 1996

Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation

scientific article published in Nature Communications

New insights into HLA-G mediated tolerance.

scientific article

Pancreas-infiltrating Th1 cells and diabetes develop in IL-12-deficient nonobese diabetic mice

scientific article published on 01 September 1999

Peanut-specific type 1 regulatory T cells induced in vitro from allergic subjects are functionally impaired.

scientific article published on 6 July 2017

Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strains.

scientific article

Protocol to assess the suppression of T-cell proliferation by human MDSC

scientific article published on 08 July 2019

Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance.

scientific article published in January 2006

Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation

scientific article (publication date: 2011)

Re-establishing immune tolerance in type 1 diabetes via regulatory T cells.

scientific article

Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance.

scientific article

Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation.

scientific article

Role of human leukocyte antigen-G in the induction of adaptive type 1 regulatory T cells.

scientific article published on 04 August 2009

Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

scientific article published on 24 October 2018

Safety of arylsulfatase A overexpression for gene therapy of metachromatic leukodystrophy.

scientific article published in September 2007

Secretory defects induced by immunosuppressive agents on human pancreatic beta-cells

scientific article published on December 2002

Subcutaneous immunization with heat shock protein-65 reduces atherosclerosis in Apoe−/− mice

scientific article published on 24 June 2011

Targeting IL-12, the key cytokine driving Th1-mediated autoimmune diseases

scientific article published on January 1997

Targeting a Pre-existing Anti-transgene T Cell Response for Effective Gene Therapy of MPS-I in the Mouse Model of the Disease

article

The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases

scientific article published on 01 December 2018

The Cellular and Molecular Mechanisms of Immuno-Suppression by Human Type 1 Regulatory T Cells ⬇️

scientific article published on February 29, 2012

The discovery of HLA-G-bearing extracellular vesicles: new perspectives in HLA-G biology

scientific article published on March 2017

The frequency of high avidity T cells determines the hierarchy of determinant spreading

scientific article

The motif for peptide binding to the insulin-dependent diabetes mellitus-associated class II MHC molecule I-Ag7 validated by phage display library

scientific article published on 01 April 2000

The role of HLA-G in immunity and hematopoiesis.

scientific article

The role of IL-12 in the pathogenesis of Th1 cell-mediated autoimmune diseases

scientific article published on October 1996

The role of interleukin 10 in the control of autoimmunity.

scientific article

The study of engraftment after hematopoietic stem cell transplantation: from the presence of mixed chimerism to the development of immunological tolerance

article

The tolerogenic interplay(s) among HLA-G, myeloid APCs, and regulatory cells.

scientific article

Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications.

scientific article published on January 2014

Tr1 cells: from discovery to their clinical application.

scientific article

Transplant tolerance to pancreatic islets is initiated in the graft and sustained in the spleen

scientific article published on 8 July 2013

Transplantation tolerance by 1,25-dihydroxyvitamin D(3)-induced costimulation blockade

scientific article

Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells

scientific article published on January 1, 2003

Type 1 regulatory T (Tr1) cells: from the bench to the bedside

scientific article published on 28 November 2012

Understanding autoimmune diabetes: insights from mouse models.

scientific article

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