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List of works by Elior Peles

A New Player in CNS Myelination

A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination

scientific article

A contactin-receptor-like protein tyrosine phosphatase beta complex mediates adhesive communication between astroglial cells and gonadotrophin-releasing hormone neurones

scientific article published in November 2007

A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier

scientific journal article

A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation.

scientific article published in August 2002

A novel Caspr mutation causes the shambling mouse phenotype by disrupting axoglial interactions of myelinated nerves

scientific journal article

A novel method for isolating Schwann cells using the extracellular domain of Necl1.

scientific article

ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons

scientific journal article

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

scientific article

Accumulation of Neurofascin at nodes of Ranvier is regulated by a Paranodal Switch

scientific article published on 16 June 2020

Altered expression of ion channel isoforms at the node of Ranvier in P0-deficient myelin mutants

scientific article published in January 2004

An essential role of MAG in mediating axon-myelin attachment in Charcot-Marie-Tooth 1A disease

scientific article

An oncogenic point mutation confers high affinity ligand binding to the neu receptor. Implications for the generation of site heterogeneity ⬇️

scientific article published on August 25, 1992

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia

scientific article

Assembly of CNS Nodes of Ranvier in Myelinated Nerves Is Promoted by the Axon Cytoskeleton

scientific article

Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy

scientific article published on 29 July 2016

Axonal spectrins: all-purpose fences

scientific article

Biochemical analysis of the ligand for the neu oncogenic receptor

article

Caspr and caspr2 are required for both radial and longitudinal organization of myelinated axons.

scientific article

Caspr regulates the processing of contactin and inhibits its binding to neurofascin

scientific article

Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels

scientific article

Caspr3 and caspr4, two novel members of the caspr family are expressed in the nervous system and interact with PDZ domains

scientific article

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase beta

scientific article

Cell-type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER-2 suggests complex ligand-receptor relationships

scientific article

Cellular form of prion protein inhibits Reelin-mediated shedding of Caspr from the neuronal cell surface to potentiate Caspr-mediated inhibition of neurite outgrowth

scientific article published on July 2010

Cellular junctions of myelinated nerves (Review).

scientific article

Close similarity between Drosophila neurexin IV and mammalian Caspr protein suggests a conserved mechanism for cellular interactions

scientific article published in March 1997

Clustering of neuronal potassium channels is independent of their interaction with PSD-95.

scientific article

Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission

scientific article

Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve

scientific article published in May 2001

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination.

scientific article

Coordinated internodal and paranodal adhesion controls accurate myelination by oligodendrocytes

scientific article published on 26 August 2019

Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS.

scientific article published in September 1999

Dependence of paranodal junctional gap width on transverse bands

Development of nodes of Ranvier

scientific article

Differential clustering of Caspr by oligodendrocytes and Schwann cells.

scientific article published in November 2009

Differential contribution of Cadm1-Cadm3 cell adhesion molecules to peripheral myelinated axons

scientific article published on 04 January 2021

Direct genesis of functional rodent and human schwann cells from skin mesenchymal precursors

scientific article published on 19 June 2014

Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells

scientific article

ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms

scientific journal article

Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology

scientific journal article

Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves

scientific journal article

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

scientific article published in January 2015

Expression of Cntnap2 (Caspr2) in multiple levels of sensory systems

scientific article

Falkor, a novel cell growth regulator isolated by a functional genetic screen

scientific article

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

scientific article published on 10 March 2016

Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy

scientific article published on July 2013

Genetic dysmyelination alters the molecular architecture of the nodal region

article

Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier

scientific article

Glial tumor cell adhesion is mediated by binding of the FNIII domain of receptor protein tyrosine phosphatase beta (RPTPbeta) to tenascin C.

scientific article published in February 2001

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier

scientific article published in July 2005

Heparan sulfate proteoglycan-dependent induction of axon branching and axon misrouting by the Kallmann syndrome gene kal-1.

scientific article

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

scientific article published on December 1990

Identification of Tmem10/Opalin as an oligodendrocyte enriched gene using expression profiling combined with genetic cell ablation

scientific article

Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions

scientific article

Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trap

scientific article

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability

scientific article published in February 2018

Importance of the HpaI-P sequence for herpes simplex virus-1 replication in the adrenal glands

scientific article

Induction of neurite outgrowth through contactin and Nr-CAM by extracellular regions of glial receptor tyrosine phosphatase beta

scientific article

Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1

scientific article (publication date: 20 April 2001)

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes

scientific article published on 21 February 2015

Internodal specializations of myelinated axons in the central nervous system

scientific article published on 01 July 2001

Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia

scientific article

Isolation of the neu/HER-2 stimulatory ligand: a 44 kd glycoprotein that induces differentiation of mammary tumor cells

scientific article

Junctional protein MAGI-3 interacts with receptor tyrosine phosphatase beta (RPTP beta) and tyrosine-phosphorylated proteins

scientific article

Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

scientific article

K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve

scientific article published in April 1999

Kv7.2 regulates the function of peripheral sensory neurons

scientific article published on 12 April 2014

Localization of Caspr2 in myelinated nerves depends on axon-glia interactions and the generation of barriers along the axon

scientific journal article

Localization of the paranodal protein Caspr in the mammalian retina ⬇️

scientific article published on September 12, 2010

Long-term maintenance of Na+ channels at nodes of Ranvier depends on glial contact mediated by gliomedin and NrCAM.

scientific article published on April 2014

Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction

scientific article

Mechanisms and roles of axon-Schwann cell interactions.

scientific article published in October 2004

Mechanisms of node of Ranvier assembly

scientific article published on 25 November 2020

Molecular domains of myelinated axons in the peripheral nervous system

scientific article

Molecular organization of the nodal region is not altered in spontaneously diabetic BB-Wistar rats

scientific article published on 01 July 2001

Molecular organization of the nodal region is not altered in spontaneously diabetic BB‐Wistar rats

Multi-ligand interactions with receptor-like protein tyrosine phosphatase beta: implications for intercellular signaling

scientific article

Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons

scientific journal article

Myelin-associated glycoprotein gene mutation causes Pelizaeus-Merzbacher disease-like disorder

scientific journal article

Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvbeta2, and Caspr

scientific article published in April 1999

N-WASP is required for membrane wrapping and myelination by Schwann cells

scientific article

N-Wasp regulates oligodendrocyte myelination

scientific article published on 29 June 2020

Neu and its ligands: from an oncogene to neural factors

scientific article published on December 1993

Neu differentiation factor (heregulin) induces expression of intercellular adhesion molecule 1: implications for mammary tumors

scientific article published on November 1993

Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

scientific article published in May 1992

Neurofascin as a target for autoantibodies in peripheral neuropathies

scientific article published on 24 October 2012

Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord

scientific article

Oncogenic forms of the neu/HER2 tyrosine kinase are permanently coupled to phospholipase C gamma ⬇️

scientific article published on August 1, 1991

Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B

scientific article

Paranodal permeability in "myelin mutants".

scientific article

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

scientific article

Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2.

scientific article published on May 2008

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

scientific article

Regulated coupling of the Neu receptor to phosphatidylinositol 3'-kinase and its release by oncogenic activation.

scientific article published on June 1992

Retention of a cell adhesion complex at the paranodal junction requires the cytoplasmic region of Caspr

scientific article

Schwann cell spectrins modulate peripheral nerve myelination

scientific article

Schwann-cell-derived CMTM6 restricts radial axonal growth

scientific article published on 07 October 2020

Secreted gliomedin is a perinodal matrix component of peripheral nerves

scientific article

Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

scientific article

Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination

scientific article published on 3 August 2016

Specific inhibition of secreted NRG1 types I-II by heparin enhances Schwann Cell myelination

Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton

scientific journal article

Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons

scientific article published on 27 April 2015

Synaptic scaffolding molecule (S-SCAM) membrane-associated guanylate kinase with inverted organization (MAGI)-2 is associated with cell adhesion molecules at inhibitory synapses in rat hippocampal neurons

scientific article

The Nodes of Ranvier: Molecular Assembly and Maintenance

scientific article published on 09 September 2015

The axonal membrane protein Caspr, a homologue of neurexin IV, is a component of the septate-like paranodal junctions that assemble during myelination

scientific article

The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin

scientific article

The clustering of voltage-gated sodium channels in various excitable membranes

scientific article published on 20 December 2019

The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves

scientific article published on 30 January 2012

The local differentiation of myelinated axons at nodes of Ranvier

scientific article

The making of a node: a co-production of neurons and glia

scientific article published on 05 July 2013

The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex

scientific article

The neurexin superfamily of Caenorhabditis elegans

scientific article published on 3 November 2010

The paranodal cytoskeleton clusters Na+ channels at nodes of Ranvier

scientific article published on 30 January 2017

The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

scientific article published on 11 September 2009

Three mechanisms assemble central nervous system nodes of Ranvier

scientific article published on May 2013

Thrombin receptor PAR-1 on myelin at the node of Ranvier: a new anatomy and physiology of conduction block

article published in 2008

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