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List of works by Walter E Haefeli

"Quality of prenatal and maternal care: bridging the know-do gap" (QUALMAT study): an electronic clinical decision support system for rural Sub-Saharan Africa

scientific article published on 10 April 2013

7-Aminoactinomycin D for apoptosis staining in flow cytometry

scientific article published on 14 July 2012

A drug database model as a central element for computer-supported dose adjustment within a CPOE system

scientific article published on 07 June 2004

A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions.

scientific article published on 8 February 2013

A prospective three-step intervention study to prevent medication errors in drug handling in paediatric care

scientific article published on 3 June 2014

A purging procedure for pantoprazole and 4-lumen catheters to prevent IV drug incompatibilities

scientific article published on 7 August 2010

A randomized controlled trial to assess the effect of a medication plan containing drug administration recommendations on patients’ drug knowledge after 2 months

scientific article published on 30 October 2016

A similarity measure for case based reasoning modeling with temporal abstraction based on cross-correlation

scientific article published on 15 December 2005

A systematic comparison of four different workup procedures for systematic toxicological analysis of urine samples using gas chromatography-mass spectrometry.

scientific article published on 31 October 2008

A systematic review of medication administration errors with transdermal patches

scientific article

Absolute Bioavailability of Microdosed Midazolam After Buccal Administration Is Dependent on Buccal Exposure Time

scientific article published on 25 September 2020

Academic detailing improves identification and reporting of adverse drug events.

scientific article

Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo

article

Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults

scientific article published in October 2004

Acyclovir-induced neurotoxicity: concentration-side effect relationship in acyclovir overdose

scientific article

Age-Dependent Impact of Medication Underuse and Strategies for Improvement

scientific article

An Electronic Medication Module to Improve Health Literacy in Patients With Type 2 Diabetes Mellitus: Pilot Randomized Controlled Trial

scientific article published on 28 April 2020

An N-of-1 Trial as an Individualized Withdrawal Treatment Approach to Psychological Methylphenidate Dependence

scientific article published on 16 October 2014

An Underestimated Factor: The Extent of Cross-Reactions Modifying APIs in Surface-Modified Liposomal Preparations Caused by Comprised Activated Lipids

scientific article published on 27 September 2020

Analysis of methylene blue in human urine by capillary electrophoresis

scientific article published on 22 September 2005

Angiotensin-converting enzyme inhibitor-induced angioedema: late onset, irregular course, and potential role of triggers

scientific article published on April 1997

Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer: A randomized, placebo-controlled, phase 1 trial.

scientific article published on 16 March 2015

Anticonvulsant hypersensitivity syndrome. 2 case reports and an overview

scientific article published on October 1999

Application of microdosed intravenous omeprazole to determine hepatic CYP2C19 activity

scientific article published on 25 November 2020

Approaching the drugs' sites of action in clinical pharmacology: new analytical options and their challenges

scientific article published on 02 September 2020

Appropriateness of timing of drug administration in electronic prescriptions

scientific article published on 10 January 2010

Arzneimittelinteraktionen

scientific article published on 01 March 2010

Assessment of a computerised decision support system for allergic rhino-conjunctivitis counselling in German pharmacy

scientific article published on 23 November 2011

Association of generalized anxiety symptoms and panic with health care costs in older age—Results from the ESTHER cohort study

article

Association of intravenous erythromycin and potentially fatal ventricular tachycardia with Q-T prolongation (torsades de pointes).

scientific article

Association of liver stiffness with hepatic expression of pharmacokinetically important genes in alcoholic liver disease

scientific article published on 24 July 2012

Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics

scientific article published on October 2004

Associations of frailty with health care costs--results of the ESTHER cohort study

scientific article

Auditory and electroencephalographic effects of midazolam and alpha-hydroxy-midazolam in healthy subjects

scientific article

Autosomal-dominant hypertension with type E brachydactyly is caused by rearrangement on the short arm of chromosome 12.

scientific article

Best practice strategies to safeguard drug prescribing and drug administration: an anthology of expert views and opinions

scientific article published on 10 March 2016

Biologics - nomenclature and classification

scientific article published in November 2011

CYP2C19 genotype is a major factor contributing to the highly variable pharmacokinetics of voriconazole

scientific article

CYP2C9 polymorphism is not a major determinant of bosentan exposure in healthy volunteers.

scientific article

CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores

scientific article published on January 2014

CYP3A activity: towards dose adaptation to the individual.

scientific article published on 7 March 2016

CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir

scientific article

Can a feedback report and training session on medication counseling for general practitioners improve patient satisfaction with information on medicines?

scientific article published on 8 March 2012

Cation exchange resins as pharmaceutical carriers for methylene blue: binding and release

scientific article published on 28 December 2007

Cellular pharmacokinetic/pharmacodynamic relationship of platinum cytostatics in head and neck squamous cell carcinoma evaluated by liquid chromatography coupled to tandem mass spectrometry

scientific article

Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters

scientific article

Characteristics of effective electronic mail messages distributed to healthcare professionals in a hospital setting

scientific article published on 20 December 2007

Characteristics of medication schedules used by elderly ambulatory patients

scientific article

Circadian carbamazepine toxicity

scientific article published on March 1994

Circulating cell adhesion molecules and endothelial markers before and after transluminal angioplasty in peripheral arterial occlusive disease

article

Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers

scientific article published on January 2014

Clarithromycin, Midazolam, and Digoxin: Application of PBPK Modeling to Gain New Insights into Drug-Drug Interactions and Co-medication Regimens

scientific article published on 7 November 2016

Clementine juice has the potential for drug interactions - In vitro comparison with grapefruit and mandarin juice

scientific article published on 24 November 2016

Clinical aspects of severe digitalis poisoning and its treatment with and without digoxin-specific antibodies. 3 case reports

scientific article published in February 1990

Clinical diagnosis of malaria and the risk of chloroquine self-medication in rural health centres in Burkina Faso

scientific article published on March 2008

Clinical pharmacists' effects on drug information requests

scientific article published on 01 January 1996

Clinically relevant drug interactions

scientific article published on 01 September 2000

Coded entry versus free-text and alert overrides: what you get depends on how you ask.

scientific article published on 24 September 2010

Comment on: Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers

scientific article published on 3 September 2014

Comparative evaluation of methods approximating drug prescription durations in claims data: modeling, simulation, and application to real data

scientific article

Comparison of the induction of P-glycoprotein activity by nucleotide, nucleoside, and non-nucleoside reverse transcriptase inhibitors

scientific article published on 13 November 2007

Comparison of the inhibitory activity of anti-HIV drugs on P-glycoprotein

scientific article published on 24 January 2007

Comparison of the pharmacodynamic effects of intravenous and oral propafenone

article

Comparison of vasodilatory responses to nitroglycerin and its dinitrate metabolites in human veins

scientific article published on December 1992

Concentration-effect relations of 5-hydroxypropafenone in normal subjects

scientific article published in May 1991

Consideration of drug absorption in customizing drug therapy

scientific article published in September 2000

Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction

scientific article published on July 2003

Correction to: Drug-Drug Interactions with Direct Oral Anticoagulants

scientific article published on 30 October 2020

Correlation between apolipoprotein B and endothelin-1-induced vasoconstriction in humans

scientific article published on 01 June 2000

Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m).

scientific article published on 4 February 2005

Cytochrome P450-3A phenotyping using midazolam is not altered by OATP1B1 polymorphisms

scientific article published on 28 February 2013

Daily honey consumption does not change CYP3A activity in humans

scientific article

Design and evaluation of an ontology-based drug application database.

scientific article

Desmethyl bosentan displays a similar in vitro interaction profile as bosentan

scientific article published on 19 December 2014

Detection and prevention of prescriptions with excessive doses in electronic prescribing systems

article

Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using A limited sampling strategy

scientific article published on 21 September 2011

Development and evaluation of a computerised clinical decision support system for switching drugs at the interface between primary and tertiary care

scientific article

Development and evaluation of an algorithm to facilitate drug prescription for inpatients with feeding tubes

scientific article published on 19 February 2015

Development of a standardized knowledge base to generate individualized medication plans automatically with drug administration recommendations

scientific article published on September 2013

Different methods, different results--how do available methods link a patient's anticholinergic load with adverse outcomes?

scientific article published on 08 September 2015

Differential modulation of the expression of important drug metabolising enzymes and transporters by endothelin-1 receptor antagonists ambrisentan and bosentan in vitro

scientific article published on 9 April 2011

Difficulties swallowing solid oral dosage forms in a general practice population: prevalence, causes, and relationship to dosage forms

scientific article

Discussion of "Attitude of physicians towards automatic alerting in computerized physician order entry systems".

scientific article published in January 2013

Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease

scientific article

Do you have any questions about your medication?

article

Dose individualisation in patients with renal insufficiency: does drug labelling support optimal management?

scientific article published on 14 December 2004

Dose-Dependent Bioavailability and CYP3A Inhibition Contribute to Non-Linear Pharmacokinetics of Voriconazole.

scientific article published on 28 May 2016

Dose-dependent increase of saquinavir bioavailability by the pharmaceutic aid cremophor EL

scientific article published on June 2002

Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced pancreatic cancer

scientific article

Dried Blood Spot Technique for the Monitoring of Ambrisentan, Bosentan, Sildenafil, and Tadalafil in Patients with Pulmonary Arterial Hypertension

scientific article published on 03 December 2015

Drug Dose Adjustments in Patients With Renal Impairment

article

Drug interaction of efavirenz and midazolam: efavirenz activates the CYP3A-mediated midazolam 1'-hydroxylation in vitro

scientific article published on 12 March 2012

Drug interactions and risk of acute bleeding leading to hospitalisation or death in patients with chronic atrial fibrillation treated with warfarin

scientific article (publication date: September 2005)

Drug interactions in primary care: impact of a new algorithm on risk determination

scientific article published on July 2004

Drug-Drug Interactions with Direct Oral Anticoagulants

scientific article published on 11 March 2020

Drug-induced hyperprolactinemia and galactorrhea

scientific article (publication date: 8 December 1992)

Drugs during pregnancy and breastfeeding: new risk categories--antibiotics as a model

scientific article

Early recurrence of withdrawal symptoms under phenytoin and chronic alcohol use

scientific article published on 01 March 1997

Efavirenz treatment and false-positive results in benzodiazepine screening tests.

scientific article published in June 2009

Effect of P-glycoprotein modulation on the clinical pharmacokinetics and adverse effects of morphine

scientific article published on September 2000

Effect of Rifampicin and CYP2B6 Genotype on Long-Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

article

Effect of methionine loading on 5-methyltetrahydrofolate, S-adenosylmethionine and S-adenosylhomocysteine in plasma of healthy humans

scientific article published in July 1996

Effect of simultaneous induction and inhibition of CYP3A by St John's Wort and ritonavir on CYP3A activity

scientific article published on 18 November 2009

Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity

scientific article published on 12 September 2012

Effects of adrenolytic mitotane on drug elimination pathways assessed in vitro

scientific article published on 27 December 2014

Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma

scientific article published on 01 January 2007

Endothelial venodilator response in carriers of genetic polymorphisms involved in NO synthesis and degradation

scientific article published in August 2004

Erratum to: On the alert: future priorities for alerts in clinical decision support for computerized physician order entry identified from a European workshop

scholarly article published in BMC Medical Informatics and Decision Making

Evaluation of conventional chest tube therapy for iatrogenic pneumothorax

scientific article

Evaluation of drug transporters' significance for multidrug resistance in head and neck squamous cell carcinoma

scientific article published on 24 August 2010

Evaluation of inhibitory potencies for compounds inhibiting P-glycoprotein but without maximum effects: f2 values

scientific article published on 4 November 2005

Evidence for activation of the sympathetic nervous system by recombinant human interleukin-1 beta in humans.

scientific article published on February 1993

Evidence for disturbed S-adenosylmethionine: S-adenosylhomocysteine ratio in patients with end-stage renal failure: a cause for disturbed methylation reactions?

article

Expression and activity of P-glycoprotein (MDR1/ABCB1) in peripheral blood mononuclear cells from patients with anorexia nervosa compared with healthy controls.

scientific article

Factors influencing alert acceptance: a novel approach for predicting the success of clinical decision support

scientific article

Fentanyl pharmacokinetics is not dependent on hepatic uptake by organic anion-transporting polypeptide 1B1 in human beings

scientific article published on 6 April 2013

First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B.

scientific article

Fluconazole dosing in continuous veno-venous haemofiltration (CVVHF): need for a high daily dose of 800 mg.

scientific article published on 25 November 2005

Fluvoxamine affects sildenafil kinetics and dynamics

scientific article

Formal prescribing errors are substantially reduced in electronic prescribing and after teaching sessions

scientific article published on 28 December 2015

Frequency of the SLCO1B1 388A>G and the 521T>C polymorphism in Tanzania genotyped by a new LightCycler®-based method

scientific article

Functional Activity of Bronchi from an Organ Donor with Fatal Asthma: Studies on Cryopreserved Bronchi

scientific article published on 01 January 1998

Functional activity and transmembrane signaling mechanisms after cryopreservation of human internal mammary arteries

scientific article published on 01 March 1998

Functional recovery of human mesenteric and coronary arteries after cryopreservation at −196° C in a serum-free medium

scientific article published on 01 April 1997

Führt die Implementierung von offenem Benchmarking in datengestützten Qualitätszirkeln zur Verbesserung der hausärztlichen Versorgung bei Arzneimittelinteraktion und Asthma bronchiale?

article published in 2011

Gebrauch und potenzielle Risiken durch nicht verschreibungspflichtige Schmerzmittel

scientific article published on 01 April 2014

Genotyping of the A6986G polymorphism of CYP3A5

scientific article published on May 2004

Glutathione S-transferase mu polymorphism does not explain variation in nitroglycerin responsiveness

journal article published in 1993

Guidance on how to achieve comprehensible patient information leaflets in four steps

scientific article

Gute Verordnungspraxis

scientific article published on 01 June 2014

Gute Verordnungspraxis im ambulanten Sektor – Qualitätsanforderungen an die Rezeptschreibung in Deutschland

scientific article published on 01 June 2014

Hair loss following typhoid fever: a forgotten phenomenon

scientific article published on 01 March 1995

Haunting medicines

article

Health service use and costs associated with excess weight in older adults in Germany

scientific article published on 31 March 2015

Health workers' knowledge of and attitudes towards computer applications in rural African health facilities

scientific article

HeiCare®: ein Projekt zur Verbesserung der sektorenübergreifenden Arzneimittelkommunikation

article published in 2011

High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

article

High prevalence of unknown co-medication in hospitalised patients

scientific article published on 10 June 2004

Highly sensitive determination of saquinavir in biological samples using liquid chromatography-tandem mass spectrometry

scientific article

How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial

scientific article

Human neuropeptide Y potentiates alpha1-adrenergic blood pressure responses in vivo.

scientific article

Hypoxia impairs systemic endothelial function in individuals prone to high-altitude pulmonary edema

scientific article published on 9 June 2005

Impact of an electronic clinical decision support system on workflow in antenatal care: The QUALMAT eCDSS in rural health care facilities in Ghana and Tanzania

scholarly article

Impact of drug interactions, dosage, and duration of therapy on the risk of hip fracture associated with benzodiazepine use in older adults

scientific article

Impact of drug transporters on cellular resistance towards saquinavir and darunavir

scientific article published on 3 September 2010

Impact of serum creatinine measurement error on dose adjustment in renal failure

scientific article published in November 2003

In vitro and ex vivo evidence for modulation of P-glycoprotein activity by progestins

scientific article published in December 2004

In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins

scientific article published on November 2005

In vitro metabolism of the opioid tilidine and interaction of tilidine and nortilidine with CYP3A4, CYP2C19, and CYP2D6.

scientific article published on 31 May 2008

In-vitro evaluation of chronic alcohol effects on expression of drug-metabolizing and drug-transporting proteins

scientific article published on 30 July 2013

Inappropriate crushing information on ward lists: cytotoxic drugs, capsules, and modified release formulations are gravely neglected

scientific article published on 28 January 2014

Indirect evidence for proton pump inhibitor failure in patients taking them independent of meals

scientific article published on 10 April 2014

Indirect evidence for stimulation of nitric oxide release by tumour necrosis factor-alpha in human veins in vivo

scientific article

Individualisierung der Evidenz – Single Case Randomized Trial

scientific article published on 01 December 2006

Individualization of drug treatment – need for optimization

article

Induction of multiple drug transporters by efavirenz

scientific article

Inequalities in out-of-pocket payments for health care services among elderly Germans--results of a population-based cross-sectional study

scientific article published on 08 January 2014

Influence of Intensive Physical Training on Urinary Nitrate Elimination and Plasma Endothelin-1 Levels in Patients With Congestive Heart Failure

article

Influence of St. Johnâ s wort on the steadystate pharmacokinetics and metabolism of bosentan

scientific article published on 01 April 2014

Influence of lipid lowering fibrates on P-glycoprotein activity in vitro.

scientific article published in January 2004

Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans

scientific article published on 01 August 1997

Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells

scientific article published on 5 December 2012

Information deficits in the summary of product characteristics preclude an optimal management of drug interactions: a comparison with evidence from the literature

scientific article published on 28 June 2005

Information on medications - How do chronically ill patients assess counselling on drugs in general practice?

scientific article published on 31 July 2009

Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthine

scientific article

Inhibition of voriconazole metabolism by chloramphenicol in an adolescent with central nervous system aspergillosis

scientific article published on 15 September 2008

Inspired oxygen fraction after cardiopulmonary bypass: effects on pulmonary function with regard to endothelin-1 concentrations and venous admixture

scientific article published in May 2000

Interaction of Hydroxychloroquine with Pharmacokinetically Important Drug Transporters

scientific article published on 25 September 2020

Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.

scientific article published on 9 June 2013

Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters

scientific article published in March 2010

Interaction of ibuprofen and probenecid with drug metabolizing enzyme phenotyping procedures using caffeine as the probe drug

scientific article published in February 2003

Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein

scientific article published on 24 September 2009

Interaction potential of etravirine with drug transporters assessed in vitro

scientific article published on 28 December 2010

Interaction potential of the endothelin-A receptor antagonist atrasentan with drug transporters and drug-metabolising enzymes assessed in vitro

scientific article

Interaction potential of the multitargeted receptor tyrosine kinase inhibitor dovitinib with drug transporters and drug metabolising enzymes assessed in vitro

scientific article published on 16 December 2014

Interaction profile of macitentan, a new non-selective endothelin-1 receptor antagonist, in vitro

scientific article published on 23 January 2013

Inverse correlation between endothelin-1-induced peripheral microvascular vasoconstriction and blood pressure in glaucoma patients ⬇️

scientific article published on October 1, 1997

Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy

scientific article

Isoniazid plus sulphadoxine-pyrimethamine can reduce morbidity of HIV-positive patients treated for tuberculosis in Africa: a controlled clinical trial

scientific article published in November 1999

Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals

scientific article published on April 2006

Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity

scientific article published on 10 October 2010

Knowledge and training needs of nurses and physicians on unsuitable drugs for patients with dysphagia or feeding tubes

L-arginine in the clinical arena: tool or remedy?

scientific article published on 01 May 1993

Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults

scientific article published on November 2014

Lack of evidence for association of high altitude pulmonary edema and polymorphisms of the NO pathway

scientific article published in January 2003

Lack of role of endothelium-derived relaxing factor in effects of alpha-adrenergic agonists in cutaneous veins in humans

scientific article

Limitations of the Anticholinergic Activity Assay and Assay-Based Anticholinergic Drug Scales

article

Local effect of transdermal isosorbide dinitrate ointment on hand vein diameter

scientific article published in December 2001

Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro

scientific article

Loneliness in the elderly is associated with the use of psychotropic drugs

scientific article published on 12 December 2014

Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

scientific article published on 16 August 2011

Longitudinal evaluation of medication underuse in older outpatients and its association with quality of life

scientific article

Low whole-blood S-adenosylmethionine and correlation between 5-methyltetrahydrofolate and homocysteine in coronary artery disease

scientific article published in June 1996

Mail surveys: obsolescent model or valuable instrument in general practice research?

scientific article published on April 2005

Management of potential drug interactions in community pharmacies: a questionnaire-based survey in Switzerland

article

Medication Underuse in Aging Outpatients with Cardiovascular Disease: Prevalence, Determinants, and Outcomes in a Prospective Cohort Study

scientific article

Medication review in German community pharmacies - Post-hoc analysis of documented drug-related problems and subsequent interventions in the ATHINA-project

scientific article published on 24 October 2016

Medication safety through e-health technology: can we close the gaps?

scientific article published on September 2013

Medizinische Probleme und Risiken bei der rabattvertragsgerechten Umstellung von Medikationen in Deutschland

Memorandum on the use of information technology to improve medication safety

scientific article published on 06 June 2014

Methods to Assess Patient Preferences in Old Age Pharmacotherapy - A Systematic Review

scientific article published on 04 March 2020

Methylenetetrahydrofolate reductase polymorphism, plasma homocysteine and age.

scientific article

Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans

scientific article

Minor role of pregnane-x-receptor for acquired multidrug resistance in head and neck squamous cell carcinoma in vitro

scientific article published on 12 March 2013

Misspellings in drug information system queries: characteristics of drug name spelling errors and strategies for their prevention

scientific article

Modulation of endothelial and smooth muscle function by bed rest and hypoenergetic, low-fat nutrition

scientific article published on 11 August 2005

Modulation of human BCRP (ABCG2) activity by anti-HIV drugs

scientific article published on 3 January 2007

Monitoring of lopinavir and ritonavir in peripheral blood mononuclear cells, plasma, and ultrafiltrate using a selective and highly sensitive LC/MS/MS assay

scientific article published on 11 December 2006

More than just crushing: a prospective pre-post intervention study to reduce drug preparation errors in patients with feeding tubes

scientific article published on 5 February 2015

Moxonidine-induced cholestatic hepatitis

scientific article published in The Lancet

Multidisciplinary pain management based on a computerized clinical decision support system in cancer pain patients

scientific article

N-acetyltransferase 2 polymorphism in patients infected with human immunodeficiency virus

scientific article published in July 1996

NKIM-6, a new immortalized human brain capillary endothelial cell line with conserved endothelial characteristics

scientific article published on 19 December 2006

Nesting doctoral students in collaborative North-South partnerships for health systems research

scientific article

Neurokinin-1 receptor antagonist R116301 inhibits substance P–induced venodilation

scientific article published on 01 November 1999

Neuropeptide Y in human hand veins: Pharmacologic characterization and interaction with cyclic guanosine monophosphate-dependent venodilators in vivo*

scientific article published on 01 December 1995

Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo

scientific article published in March 1995

No difference in genotype frequencies of polymorphisms of the nitric oxide pathway between Caucasian normal and high tension glaucoma patients.

scientific article

Nonlinear kinetics of propafenone metabolites in healthy man

scientific article published on 01 January 1990

Objective assessment of nonadherence and unknown co-medication in hospitalized patients

scientific article

Off-label use in long-term anticoagulation after liver transplantation due to phenprocoumon-induced hepatic failure

scientific article published in December 2005

On the alert: future priorities for alerts in clinical decision support for computerized physician order entry identified from a European workshop

scientific article

One-year follow-up on procedure to prevent i.v. drug incompatibilities in an intensive care unit

scientific article published on 01 July 2009

Opportunities to reduce medication regimen complexity: a retrospective analysis of patients discharged from a university hospital in Germany

scientific article published in January 2013

Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics

scientific article published in July 2005

Optimizing information on drug exposure by collection of package code information in questionnaire surveys

scientific article published on 01 September 2007

Oral contraception does not alter single dose saquinavir pharmacokinetics in women

scientific article published in March 2004

Overconsumption detected by electronic drug monitoring requires subtle interpretation

scientific article published on January 2000

P-glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine and paramethoxyamphetamine

scientific article published in December 2003

Particularities of drug dosing at the beginning and end of therapy

scientific article published in October 2008

Patient knowledge on oral anticoagulants: results of a questionnaire survey in Germany and comparison with the literature

scientific article published in June 2008

Patient recruitment in clinical studies

scientific article

Patient-specific electronic decision support reduces prescription of excessive doses

scientific article published on 27 April 2010

Patientensicherheit durch computerbasierte Arzneimittelinformationen

scientific article published on 01 June 2009

Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers

scientific article published on 09 May 2019

Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40.

scientific article published in May 2003

Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria

scientific article published on 13 October 2004

Pharmacokinetic interaction of intravenous fentanyl with ketoconazole

scientific article

Pharmacokinetic interaction profile of riociguat, a new soluble guanylate cyclase stimulator, in vitro

scientific article published on 21 March 2014

Pharmacokinetics and pharmacodynamics of clomethiazole after oral and rectal administration in healthy subjects

scientific article published on 01 May 1999

Pharmacokinetics of 5-Aminofluorescein-Albumin, a Novel Fluorescence Marker of Brain Tumors During Surgery

scientific article published on 26 October 2010

Pharmacokinetics of a netilmicin loading dose on the first postnatal day in preterm neonates with very low gestational age.

scientific article published on 25 July 2006

Pharmacokinetics of linezolid in septic patients with and without extended dialysis

scientific article published on 16 December 2009

Pharmacokinetics of sulfobutylether-beta-cyclodextrin and voriconazole in patients with end-stage renal failure during treatment with two hemodialysis systems and hemodiafiltration

scientific article

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype

scientific article

Pharmacokinetics, tissue concentrations, and safety of the antifungal agent voriconazole in chickens

scientific article published in September 2008

Pilot study to assess the influence of an enhanced medication plan on patient knowledge at hospital discharge

scientific article published on 30 July 2014

Pilot study to test the feasibility of a trial design and complex intervention on PRIoritising MUltimedication in Multimorbidity in general practices (PRIMUMpilot)

scientific article published on 25 July 2016

Plasma LDL cholesterol has no impact on P-glycoprotein (MDR1/ABCB1) activity in human peripheral blood mononuclear cells

Platelet surface activation markers after DDAVP infusion in healthy subjects

scientific article published on 01 September 1995

Poor solubility limiting significance of in-vitro studies with HIV protease inhibitors

scientific article published in March 2002

Possible risk for cardiac arrhythmia related to intravenous erythromycin

scientific article published on January 1, 1992

Potent Inhibition of Cytochrome P450IID6 (Debrisoquin 4-Hydroxylase) by Flecainide In Vitro and In Vivo ⬇️

scientific article published on May 1, 1990

Potent cytochrome P450 2C19 genotype–related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir

scientific article published on 03 July 2006

Potential of novel antiretrovirals to modulate expression and function of drug transporters in vitro

scientific article published on 19 January 2011

Potential of the novel antiretroviral drug rilpivirine to modulate the expression and function of drug transporters and drug-metabolising enzymes in vitro

scientific article published on 18 February 2013

Prescribing errors in patients with documented drug allergies: comparison of ICD-10 coding and written patient notes

scientific article published on 3 May 2009

Prevention of adverse drug reactions in intensive care patients by personal intervention based on an electronic clinical decision support system.

scientific article published on 9 February 2010

Prevention of intravenous drug incompatibilities in an intensive care unit

scientific article published on 01 October 2008

Prioritising the prevention of medication handling errors

scientific article published on 12 September 2008

Pro-active provision of drug information as a technique to address overdosing in intensive-care patients with renal insufficiency

scientific article published on 25 March 2009

Process of translation and cross-cultural adaptation of two Australian instruments to evaluate the physician-pharmacist collaboration in Germany

scientific article published on 23 March 2019

Prolonged sedation due to accumulation of conjugated metabolites of midazolam

scientific article published on July 1995

Prolonged-Release Tacrolimus Is Less Susceptible to Interaction With the Strong CYP3A Inhibitor Voriconazole in Healthy Volunteers

scientific article published on 10 July 2019

Promising adoption of an electronic clinical decision support system for antenatal and intrapartum care in rural primary healthcare facilities in sub-Saharan Africa: The QUALMAT experience

scientific article

Prospective pilot intervention study to prevent medication errors in drugs administered to children by mouth or gastric tube: a programme for nurses, physicians and parents

scientific article published on 8 April 2010

Quality markers of drug information on the Internet: an evaluation of sites about St. John's wort

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Quality of antenatal and childbirth care in rural health facilities in Burkina Faso, Ghana, and Tanzania: an intervention study

scientific article published on 26 October 2015

Quality of drug information on the World Wide Web and strategies to improve pages with poor information quality. An intervention study on pages about sildenafil

scientific article published in January 2004

Quantification of cationic anti-malaria agent methylene blue in different human biological matrices using cation exchange chromatography coupled to tandem mass spectrometry

scientific article published on 26 January 2008

Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry.

scientific article published on 15 January 2012

Quantification of retinoid concentrations in human serum and brain tumor tissues

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Quantification of vorinostat and its main metabolites in plasma and intracellular vorinostat in PBMCs by liquid chromatography coupled to tandem mass spectrometry and its relation to histone deacetylase activity in human blood

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Quantitative bile acid profiling by liquid chromatography quadrupole time-of-flight mass spectrometry: monitoring hepatitis B therapy by a novel Na(+)-taurocholate cotransporting polypeptide inhibitor

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Quinaprilat Induces Arterial Vasodilation Mediated by Nitric Oxide in Humans

scientific article published on 01 October 1997

Rahmenbedingungen ärztlicher Forschung am Menschen - Algorithmen zu Planung und Organisation

Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI-IM-MS/MS Assay

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Rapid and reliable genotyping of the C181T polymorphism in the bradykinin B2 receptor gene.

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Rapid detection of polymorphisms of the nitric oxide cascade

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Reasons for Drug Administration Problems and Perceived Needs for Assistance of Patients, Family Caregivers, and Nurses: A Qualitative Study

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Recurrent ventricular fibrillation in mianserin intoxication

scientific article published in February 1991

Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity

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Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid

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Requirements for a successful implementation of drug interaction information systems in general practice: results of a questionnaire survey in Germany

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Response to "can CYP3A activity be evaluated for drug interaction using a nanogram dose of probe drug?": evaluation of CYP3A activity with microdoses of midazolam.

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Responsiveness to bradykinin in veins of hypercholesterolemic humans

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Reversible ageusia associated with losartan

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Rhabdomyolysis due to interaction of simvastatin with mibefradil

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Risk of cataract in patients treated with statins.

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Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement

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Rivaroxaban and macitentan can be co-administered without dose adjustment but the combination of rivaroxaban and St. John´s Wort should be avoided

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Role of NR1I2 (pregnane X receptor) polymorphisms in head and neck squamous cell carcinoma

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Role of basal and stimulated release of nitric oxide in the regulation of radial artery caliber in humans.

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Role of nitric oxide in the regulation of the mechanical properties of peripheral conduit arteries in humans

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Rule-based standardised switching of drugs at the interface between primary and tertiary care

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Safeguarding the process of drug administration with an emphasis on electronic support tools

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Safety and efficacy of a two-compartment Bayesian feedback program for therapeutic tobramycin monitoring in the daily clinical use and comparison with a non-Bayesian one-compartment model

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Severe hypotension and bradycardia associated with verapamil and clarithromycin

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Significant pharmacokinetic and pharmacodynamic interaction of warfarin with the NO-independent sGC activator HMR1766.

scientific article published in January 2007

Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure

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Simultaneous determination of hypericin and hyperforin in human plasma with liquid chromatography-tandem mass spectrometry

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Simultaneous phenotyping of CYP2E1 and CYP3A using oral chlorzoxazone and midazolam microdoses

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St. John's wort treatment in women bears risks beyond pharmacokinetic drug interactions

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Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry

Standardized documentation of drug recommendations in discharge letters--a contribution to quality management in cooperative care

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Structure and Content of Drug Monitoring Advices Included in Discharge Letters at Interfaces of Care: Exploratory Analysis Preceding Database Development

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Structured medication management in primary care - a tool to promote medication safety

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Subconstrictor doses of neuropeptide Y potentiate alpha 1-adrenergic venoconstriction in vivo

scientific article published in September 1996

Substance P in human hand veins in vivo: Tolerance, efficacy, potency, and mechanism of venodilator action*

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Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers

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Substantial reduction of inappropriate tablet splitting with computerised decision support: a prospective intervention study assessing potential benefit and harm

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Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease: two case reports

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Successful strategy to improve the specificity of electronic statin-drug interaction alerts

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Swallowing Tablets and Capsules Increases the Risk of Penetration and Aspiration in Patients with Stroke-Induced Dysphagia

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Tablet splitting: patients and physicians need better support

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Tabletten teilen

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Tailoring of alerts substantially reduces the alert burden in computerized clinical decision support for drugs that should be avoided in patients with renal disease

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Telaprevir is a substrate and moderate inhibitor of P-glycoprotein, a strong inductor of ABCG2, but not an activator of PXR in vitro

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The A14-scale: development and evaluation of a questionnaire for assessment of adherence and individual barriers

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The effect of induction of CYP3A4 by St John's wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype

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The frequency of inappropriate tablet splitting in primary care.

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The impact of pharmaceutical care interventions for medication underuse in older people: a systematic review and meta-analysis

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The mechanism of cryoinjury: In vitro studies on human internal mammary arteries.

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Therapie der pulmonal arteriellen Hypertonie (PAH)

Timing of Invasive Procedures in Therapy for Primary and Secondary Spontaneous Pneumothorax

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Torsade de pointes during anti-arrhythmia treatment with amiodarone

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Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study

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Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans.

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Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters

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Two techniques to make swallowing pills easier

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Ultra-sensitive and selective quantification of endothelin-1 in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry

scientific article published on 29 April 2017

Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry after chlorzoxazone microdosing.

scientific article published on 31 May 2016

Undeclared exposure to St. John's Wort in hospitalized patients

scientific article published in October 2004

Use of microdose phenotyping to individualise dosing of patients

scientific article published on 30 April 2015

Using the Causal Inference Framework to Support Individualized Drug Treatment Decisions Based on Observational Healthcare Data

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Verabreichungsfehler – welche Informationen braucht ein Patient um seine Arzneimittel-Therapie sicher durchzuführen?

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Vigabatrin dosing during haemodialysis

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Voriconazole concentration in human aqueous humor and plasma during topical or combined topical and systemic administration for fungal keratitis

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Voriconazole-induced QT interval prolongation and ventricular tachycardia: a non-concentration-dependent adverse effect.

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What, if all alerts were specific - estimating the potential impact on drug interaction alert burden

scientific article published on 13 January 2014

Which Factors Affect Out-of-pocket Payments for Health Care Services Among Elderly Germans? Results of a Longitudinal Study

scientific article published on 9 November 2015

Willingness to pay for health insurance among the elderly population in Germany

scientific article published on 20 December 2014

Xanthine oxidase inhibition by allopurinol affects the reliability of urinary caffeine metabolic ratios as markers for N -acetyltransferase 2 and CYP1A2 activities

scientific article published on 01 January 1999

[Anti-retroviral therapy and antiepileptics. Case report and discussion]

scientific article published on 01 July 1998

[Clinico-pharmacological case (4). Epileptic seizure as an unwanted drug effect on theophylline poisoning]

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[Conviction as a basis for compliance and strategies for improving compliance]

scientific article published on 01 October 1999

[Drug interactions with the cytochrome P-450 system]

scientific article published on 01 January 2000

[Drug-induced Stevens-Johnson syndrome in a patient with AIDS]

scientific article published on 01 August 1993

[How complete is the Germany-wide standardised medication list ("Bundeseinheitlicher Medikationsplan")? An analysis at hospital admission.]

scientific article published on 06 October 2020

[Off label use in long-term anticoagulation after liver transplantation due to phenprocoumon-induced hepatic failure]

scientific article published on 01 July 2006

[Role of nitric oxide in flow-dependent vasodilation of human peripheral arteries in vivo]

scientific article published on 01 August 1994

[Role of nitric oxide in the regulation of the mechanical properties of peripheral muscular arteries in man]

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[Tablets in stool? A common problem!]

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[The most dangerous drug in patients over 70 years old]

scientific article published on 01 May 1995

e-SPC - delivering drug information in the 21st century: developing new approaches to deliver drug information to prescribers

scientific article published on January 2012

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