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List of works by Ken Op de Beeck

APR-246 (PRIMA-1(MET)) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

scientific article published on 11 March 2016

Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cell

scientific article

Determination of the Potential Tumor-Suppressive Effects of Gsdme in a Chemically Induced and in a Genetically Modified Intestinal Cancer Mouse Model

scientific article published on 20 August 2019

Ectopic microRNA-150-5p transcription sensitizes glucocorticoid therapy response in MM1S multiple myeloma cells but fails to overcome hormone therapy resistance in MM1R cells

scientific article

Long-term acquired everolimus resistance in pancreatic neuroendocrine tumours can be overcome with novel PI3K-AKT-mTOR inhibitors

scientific article published on March 2016

MDM2 SNP309 and SNP285 Act as Negative Prognostic Markers for Non-small Cell Lung Cancer Adenocarcinoma Patients.

scientific article

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

scientific article published on 16 April 2019

Overcoming cetuximab resistance in HNSCC: the role of AURKB and DUSP proteins

scientific article published on 2 September 2014

PDX1 DNA Methylation Distinguishes Two Subtypes of Pancreatic Neuroendocrine Neoplasms with a Different Prognosis

scientific article published on 04 June 2020

Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells

scientific article published on 03 February 2014

Prognostic and Predictive Value of RAS Gene Mutations in Colorectal Cancer: Moving Beyond KRAS Exon 2.

scientific article published on 07 September 2015

Role of DFNA5 in hearing loss and cancer - a comment on Rakusic et al.

scientific article published on 15 September 2015

The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein

scientific article

The Gasdermin E Gene Has Potential as a Pan-Cancer Biomarker, While Discriminating between Different Tumor Types

scientific article published on 18 November 2019

The Genetic Landscape of Malignant Pleural Mesothelioma: Results from Massively Parallel Sequencing

scientific article

The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer

scientific article

The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies

scientific article published on 04 December 2019

The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways

scientific article published on 16 July 2015

Towards Prognostic Profiling of Non-Small Cell Lung Cancer: New Perspectives on the Relevance of Polo-Like Kinase 1 Expression, the TP53 Mutation Status and Hypoxia

scientific article

Whole-exome characterization of pancreatic neuroendocrine tumor cell lines BON-1 and QGP-1.

scientific article

Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway

scientific article

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