List of works by Miquel Vila

Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.

scientific article

Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.

scientific article published in July 2005

Alpha-synuclein and protein degradation pathways in Parkinson's disease: a pathological feed-back loop

scientific article published on 13 March 2013

Alpha-synuclein propagation: New insights from animal models

scientific article published on 08 September 2015

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

scientific article published on February 2000

Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins

scientific article published on August 2010

Autophagic Pathways and Parkinson Disease

scholarly article published 2014

BAX channel activity mediates lysosomal disruption linked to Parkinson disease.

scientific article published on 26 March 2014

Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson's disease pathogenesis

article

Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy.

scientific article published on 6 May 2016

Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

scholarly article

Consequences of nigrostriatal denervation on the gamma-aminobutyric acidic neurons of substantia nigra pars reticulata and superior colliculus in parkinsonian syndromes

scientific article

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

scholarly article

DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease

scientific article published on 12 June 2014

Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.

scientific article published on 8 March 2012

Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells

scientific article published on 17 November 2011

Erratum to: Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons.

scientific article published on 5 May 2017

Evolution of changes in neuronal activity in the subthalamic nucleus of rats with unilateral lesion of the substantia nigra assessed by metabolic and electrophysiological measurements

scientific article published on 01 January 2000

Fighting neurodegeneration with rapamycin: mechanistic insights

scientific article (publication date: 20 July 2011)

Functional Rescue of Dopaminergic Neuron Loss in Parkinson's Disease Mice After Transplantation of Hematopoietic Stem and Progenitor Cells.

scientific article published on 19 April 2016

Functional activity of zona incerta neurons is altered after nigrostriatal denervation in hemiparkinsonian rats

scientific article (publication date: March 2000)

Glial cell response: A pathogenic factor in Parkinson's disease.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates

scientific article published on 13 May 2020

Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease

scientific article

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

article

Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS

scientific article published on 01 August 2002

Interfering with programmed cell death in neurodegenerative diseases: insights from experimental animal models

scientific article published on 01 June 2004

Intracellular crowding by age-dependent neuromelanin accumulation disrupts neuronal proteostasis and triggers Parkinson disease pathology

scientific article published on 03 September 2019

Involvement of Cellular Prion Protein in α-Synuclein Transport in Neurons.

scientific article published on 22 February 2017

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

scholarly article

L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease

scientific article published in July 2004

LY293558, an AMPA glutamate receptor antagonist, prevents and reverses levodopa-induced motor alterations in Parkinsonian rats

scientific article published in October 2001

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

scientific article published in June 2001

Lack of pathogenic potential of peripheral α-synuclein aggregates from Parkinson's disease patients

scientific article published on 8 February 2018

Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.

scientific article published on 18 February 2014

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.

scientific article

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

scientific journal article

Lysosomal impairment in Parkinson's disease

scientific article published on 11 April 2013

Lysosomal membrane permeabilization in Parkinson disease

scientific article published on 01 January 2011

Metabolic activity of excitatory parafascicular and pedunculopontine inputs to the subthalamic nucleus in a rat model of Parkinson's disease.

scientific article published on January 2000

Metabolic activity of the basal ganglia in parkinsonian syndromes in human and non-human primates: a cytochrome oxidase histochemistry study

scientific article published in April 1996

Metabolic changes in the basal ganglia of patients with Huntington's disease: an in situ hybridization study of cytochrome oxidase subunit I mRNA.

scientific article

Mitochondrial alterations in Parkinson's disease: new clues

scientific article published on 30 August 2008

Molecular pathways of programmed cell death in experimental Parkinson's disease.

scientific article published on 02 July 2008

Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease

scientific article published on 24 February 2020

NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease ⬇️

scientific article published on April 29, 2003

Neuromelanin, aging, and neuronal vulnerability in Parkinson's disease

scientific article published on 28 June 2019

Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease

scientific article published on 17 July 2009

Oligomeric α-synuclein is toxic in vivo

scientific article published on 01 August 2011

Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency.

scientific article

Pathogenic lysosomal depletion in Parkinson's disease

scientific article published on September 2010

Pathogenic role of glial cells in Parkinson's disease.

scientific article

Persistent MDMA-induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice

scientific article published on 24 September 2008

Re-evaluation of the functional anatomy of the basal ganglia in normal and Parkinsonian states

scientific article

Selective neuroprotective effects of the S18Y polymorphic variant of UCH-L1 in the dopaminergic system.

scientific article published on 10 November 2011

Selective noradrenergic vulnerability in α-synuclein transgenic mice

scientific article published on 18 January 2009

Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease.

scientific article published on 29 November 2017

Striatal expression of substance P and methionin-enkephalin in genes in patients with Parkinson's disease

scientific article published on 01 October 1995

Subthalamotomy in parkinsonian monkeys. Behavioural and biochemical analysis

scientific article published in October 1996

Systemic administration of NMDA and AMPA receptor antagonists reverses the neurochemical changes induced by nigrostriatal denervation in basal ganglia

scientific article

Targeting programmed cell death in neurodegenerative diseases ⬇️

scientific article published on May 1, 2003

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

scientific article published on 03 June 2015

The Parkinson Disease Mitochondrial Hypothesis: Where Are We at?

scientific article

The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity

scientific article published on 10 February 2018

The rotenone model of Parkinson's disease.

scientific article published in July 2003

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

scholarly article

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