Search filters

List of works by Frank Balis

A Phase 1 Trial and Pharmacokinetic Study of Cediranib, an Orally Bioavailable Pan–Vascular Endothelial Growth Factor Receptor Inhibitor, in Children and Adolescents With Refractory Solid Tumors ⬇️

scientific article published on November 8, 2010

A Phase I clinical trial of ixabepilone (BMS-247550), an epothilone B analog, administered intravenously on a daily schedule for 3 days.

scientific article published in May 2005

A Phase I/II Study of the Protease Inhibitor Indinavir in Children With HIV Infection ⬇️

scientific article published on July 1, 1998

A Phase I/II Study of the Protease Inhibitor Ritonavir in Children With Human Immunodeficiency Virus Infection ⬇️

scientific article published on March 1, 1998

A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer.

scientific article

A phase 1 study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 7 days every 21 days in pediatric patients with solid tumors.

scientific article

A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: A Pediatric Oncology Branch, NCI and Children's Oncology Group Study

scientific article published on 01 October 2007

A phase I and pharmacokinetic study of trimetrexate using a 24-hour continuous-injection schedule

scientific article published on 01 May 1990

A phase I study of ABT-751, an orally bioavailable tubulin inhibitor, administered daily for 21 days every 28 days in pediatric patients with solid tumors

scientific article

A phase I trial and pharmacokinetic study of a 24-hour infusion of trabectedin (Yondelis®, ET-743) in children and adolescents with relapsed or refractory solid tumors

scientific article

A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report.

scientific article

A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study

scientific article

A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study.

scientific article

A phase II trial of continuous-infusion 6-mercaptopurine for childhood leukemia

scientific article published on 01 January 1992

A phase II trial of continuous-infusion 6-mercaptopurine for childhood solid tumors

scientific article

Altered phenytoin clearance during intensive chemotherapy for acute lymphoblastic leukemia

scientific article published on 01 June 1988

Automated Volumetric Growth Plate Measurement Using Magnetic Resonance Imaging for Monitoring Skeletal Toxicity in Children Treated on Investigational Drug Trials ⬇️

scientific article published on September 15, 2011

Cerebrospinal fluid and plasma pharmacokinetics of morphine infusions in pediatric cancer patients and rhesus monkeys

scientific article published on 01 September 1987

Cerebrospinal fluid pharmacokinetics and toxicology of intraventricular and intrathecal arabinosyl-5-azacytosine (fazarabine, NSC 281272) in the nonhuman primate

scientific article published on 01 May 1993

Characteristics and outcome of pediatric patients enrolled in phase I oncology trials

scientific article published on 01 June 2008

Characteristics of children enrolled in treatment trials for NF1-related plexiform neurofibromas.

scientific article published on October 2009

Clinical drug development for childhood cancers

scientific article published on 01 February 2009

Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro

scientific article published on January 2010

Clinical pharmacokinetics of commonly used anticancer drugs.

scientific article

Clinical pharmacology of 2',3'-dideoxyinosine in human immunodeficiency virus-infected children.

scientific article published in January 1992

Commentary

scientific article published in December 2010

Comparative pharmacokinetics, safety, and tolerability of two sources of ch14.18 in pediatric patients with high-risk neuroblastoma following myeloablative therapy

scientific article published on 20 January 2016

Current Pharmacological Treatment Approaches to Central Nervous System Leukaemia

scientific article published on May 1, 1991

Cytotoxicity and DNA damage associated with pyrazoloacridine in MCF-7 breast cancer cells

scientific article published on 01 June 1996

Desulfuration of 6-mercaptopurine. The basis for the paradoxical cytotoxicity of thiopurines in cultured human leukemic cells

scientific article published on 01 November 1993

Dexrazoxane as a cardioprotectant in children receiving anthracyclines

scientific article published on 4 November 2010

Diagnosis of Beckwith-Wiedemann syndrome in children presenting with Wilms tumor

scientific article published on 22 June 2018

Dosing anticancer drugs in infants: Current approach and recommendations from the Children's Oncology Group's Chemotherapy Standardization Task Force

scientific article published on 16 May 2017

Effect of continuous-infusion zidovudine therapy on neuropsychologic functioning in children with symptomatic human immunodeficiency virus infection.

scientific article published in December 1990

Effect of fluconazole on the pharmacokinetics of doxorubicin in nonhuman primates.

scientific article

Evaluation and treatment of fever in the non-neutropenic child with cancer.

scientific article published on August 2003

Extracellular fluid concentrations of cisplatin, carboplatin, and oxaliplatin in brain, muscle, and blood measured using microdialysis in nonhuman primates.

scientific article published on 7 August 2009

Fluconazole penetration into cerebrospinal fluid: implications for treating fungal infections of the central nervous system

scientific article published on 01 January 1988

Fluorescence properties of pteridine nucleoside analogs as monomers and incorporated into oligonucleotides

scientific article published on 01 January 1997

Folate and methotrexate polyglutamate tissue levels in rhesus monkeys following chronic low-dose methotrexate.

scientific article published in January 1987

Fundamental problems with pediatric adaptive dosing of carboplatin using nuclear-medicine-based estimates of renal function

scientific article published on 15 February 2019

Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.

scientific article

Incorporation of a fluorescent guanosine analog into oligonucleotides and its application to a real time assay for the HIV-1 integrase 3'-processing reaction

scientific article

Influence of food intake on bioavailability of oral 6-mercaptopurine in children with acute lymphoblastic leukemia.

scientific article published in January 1986

Intrathecal 5-fluorouracil in the rhesus monkey

scientific article published on January 1, 1992

Intrathecal administration of topotecan in nonhuman primates

scientific article published on 01 January 1995

Loss of Smad3 in acute T-cell lymphoblastic leukemia.

scientific article

Mixing during intravertebral arterial infusions in an in vitro model.

scientific article

NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.

scientific article published on 10 January 2007

Pediatric phase I trial and pharmacokinetic study of dasatinib: a report from the children's oncology group phase I consortium

scientific article

Pediatric phase I trial and pharmacokinetic study of the platelet-derived growth factor (PDGF) receptor pathway inhibitor SU101.

scientific article published on 4 March 2004

Pediatric phase I trial design using maximum target inhibition as the primary endpoint

scientific article

Pencil beam scanning proton therapy for treatment of the retroperitoneum after nephrectomy for Wilms tumor: A dosimetric comparison study

scientific article published on 27 August 2016

Pharmacokinetic and pharmacodynamic study of tariquidar (XR9576), a P-glycoprotein inhibitor, in combination with doxorubicin, vinorelbine, or docetaxel in children and adolescents with refractory solid tumors.

scientific article published on 20 October 2015

Pharmacokinetic drug interactions of commonly used anticancer drugs.

scientific article published on May 1986

Pharmacokinetically guided phase 1 trial of the IGF-1 receptor antagonist RG1507 in children with recurrent or refractory solid tumors.

scientific article

Pharmacokinetics and cerebrospinal fluid penetration of daunorubicin, idarubicin, and their metabolites in the nonhuman primate model

scientific article published on 01 January 1999

Pharmacokinetics and pharmacodynamic effects of 5-fluorouracil given as a one-hour intravenous infusion.

scientific article

Pharmacokinetics and tolerability of ventricularly administered superoxide dismutase in monkeys and preliminary clinical observations in familial ALS

scientific article published on 01 May 1995

Pharmacokinetics of PEG-L-asparaginase and plasma and cerebrospinal fluid L-asparagine concentrations in the rhesus monkey

scientific article published on 01 January 1993

Pharmacokinetics of mercaptopurine in children with acute lymphocytic leukemia

scientific article published on 01 November 1990

Pharmacokinetics of orally administered ABT-751 in children with neuroblastoma and other solid tumors.

scientific article published in January 2010

Pharmacokinetics of phenylacetate administered as a 30-min infusion in children with refractory cancer

scientific article published on 15 July 2003

Pharmacokinetics of taxol and doxorubicin administered alone and in combination by continuous 72-hour infusion

scientific article published on 01 January 1994

Pharmacokinetics of temozolomide administered in combination with O6-benzylguanine in children and adolescents with refractory solid tumors.

scientific article published on 9 May 2009

Pharmacokinetics of the chimeric anti-GD2 antibody, ch14.18, in children with high-risk neuroblastoma.

scientific article published on 12 September 2014

Pharmacokinetics of zidovudine administered intravenously and orally in children with human immunodeficiency virus infection.

scientific article

Pharmacokinetics, cerebrospinal fluid penetration, and metabolism of piroxantrone in the rhesus monkey

scientific article published on 01 November 1993

Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma

scientific article

Phase 1 trial and pharmacokinetic study of the farnesyl transferase inhibitor tipifarnib in children and adolescents with refractory leukemias: A report from the Children's Oncology Group ⬇️

scientific article published on September 21, 2010

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.

scientific article published on 04 February 2014

Phase I study of O6-benzylguanine and temozolomide administered daily for 5 days to pediatric patients with solid tumors.

scientific article published in October 2005

Phase I trial and pharmacokinetic study of BMS-247550, an epothilone B analog, administered intravenously on a daily schedule for five days.

scientific article published on May 2003

Phase I trial and pharmacokinetic study of ixabepilone administered daily for 5 days in children and adolescents with refractory solid tumors

scientific article published on 15 December 2008

Phase I trial and pharmacokinetic study of sorafenib in children with neurofibromatosis type I and plexiform neurofibromas.

scientific article published on 7 September 2012

Phase I trial of lobradimil (RMP-7) and carboplatin in children with brain tumors.

scientific article

Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group.

scientific article published on 12 January 2006

Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.

scientific article published on 22 April 2014

Phase II trial of sequential methotrexate and 5-fluorouracil with leucovorin in children with sarcomas

scientific article published on 01 May 1990

Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group.

scientific article

Plasma and CNS pharmacokinetics of O4-benzylfolic acid (O4BF) and metabolite in a non-human primate model.

scientific article

Plasma and cerebrospinal fluid pharmacokinetics of 9-aminocamptothecin (9-AC), irinotecan (CPT-11), and SN-38 in nonhuman primates

scientific article published on 01 January 1998

Plasma and cerebrospinal fluid pharmacokinetics of imatinib after administration to nonhuman primates

scientific article published in April 2004

Plasma and cerebrospinal fluid pharmacokinetics of intravenously administered ABT-751 in non-human primates

scientific article published on 23 December 2006

Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates.

scientific article published on 25 October 2007

Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study.

scientific article published in March 2001

Probe calibration in transient microdialysis in vivo.

scientific article published in March 2001

Real-time fluorescence assay for O6-alkylguanine-DNA alkyltransferase.

scientific article published on June 2000

Retained platinum uptake and indifference to p53 status make novel transplatinum agents active in platinum-resistant cells compared to cisplatin and oxaliplatin.

scientific article published on March 2012

Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study.

scientific article

Sorafenib and sunitinib.

scientific article published on August 2009

Synthesis and fluorescence characterization of pteridine adenosine nucleoside analogs for DNA incorporation.

scientific article

The cytotoxicity of thioguanine vs mercaptopurine in acute lymphoblastic leukemia

scientific article published on 01 November 1994

The effect of amitriptyline on the central nervous system penetration of methotrexate.

scientific article

The extent of chromosomal aberrations induced by chemotherapy in non-human primates depends on the schedule of administration

scientific article published on June 2005

The ganglioside GD2 as a circulating tumor biomarker for neuroblastoma

scientific article published on 14 October 2019

The influence of route of administration on the hepatic uptake of methotrexate

scientific article published on 01 January 1986

The legacy of cancer therapy in children.

scientific article

The plasma and cerebrospinal fluid pharmacokinetics of erlotinib and its active metabolite (OSI-420) after intravenous administration of erlotinib in non-human primates.

scientific article published on 12 October 2007

The plasma and cerebrospinal fluid pharmacokinetics of sorafenib after intravenous administration in non-human primates.

scientific article

The plasma and cerebrospinal fluid pharmacokinetics of the platinum analog satraplatin after intravenous administration in non-human primates

scientific article published on 26 June 2011

Time to disease progression in children with relapsed or refractory neuroblastoma treated with ABT-751: a report from the Children's Oncology Group (ANBL0621).

scientific article published on 18 December 2013

Trabectedin.

scientific article published on 14 August 2009

Treatment of accidental intrathecal methotrexate overdose with intrathecal carboxypeptidase G2.

scientific article published in October 2004

Vandetanib successfully controls medullary thyroid cancer-related Cushing syndrome in an adolescent patient.

scientific article

Variability in the oral bioavailability of all-trans-retinoic acid

scientific article published on 01 June 1993

Very high-dose methotrexate (33.6 g/m(2)) as central nervous system preventive therapy for childhood acute lymphoblastic leukemia: results of National Cancer Institute/Children's Cancer Group trials CCG-191P, CCG-134P and CCG-144P

scientific article published on 01 December 2006

Zidovudine concentration in brain extracellular fluid measured by microdialysis: steady-state and transient results in rhesus monkey.

scientific article published in June 2002

Paulina is supported by:

About Paulina

Help