List of works by Shakeel Modak

5-day/5-drug myeloablative outpatient regimen for resistant neuroblastoma

scientific article

A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors

scientific article

A focal lesion in the falx cerebri: Harbinger of classic stage 4 neuroblastoma in an infant cured despite residual disease after minimal therapy.

scientific article

A novel image-based system for risk stratification in patients with desmoplastic small round cell tumor.

scientific article published on 6 March 2018

A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors

scientific article

A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors

scientific article

A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma

scientific article published on 20 September 2016

Acute myeloid leukemia therapy elicits durable complete response in chemoradio-resistant metastatic paraganglioma.

scientific article

Acute pain relief after Mantram meditation in children with neuroblastoma undergoing anti-GD2 monoclonal antibody therapy.

scientific article

Adoptive immunotherapy with haploidentical natural killer cells and Anti-GD2 monoclonal antibody m3F8 for resistant neuroblastoma: Results of a phase I study

scientific article published on 10 May 2018

Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma

scientific article

Anti-GD2 immunotherapy for neuroblastoma.

scientific article published on 7 August 2017

Anti-idiotypic antibody as the surrogate antigen for cloning scFv and its fusion proteins

scientific article published on 01 December 2002

Anti-idiotypic antibody facilitates scFv chimeric immune receptor gene transduction and clonal expansion of human lymphocytes for tumor therapy

scientific article published on August 2003

Antibody-based targeted radiation to pediatric tumors.

scientific article

Arsenic Trioxide as a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study

scientific article

Assessment of Organ Dosimetry for Planning Repeat Treatments of High-Dose 131I-MIBG Therapy: 123I-MIBG Versus Posttherapy 131I-MIBG Imaging.

scientific article published in October 2017

Bevacizumab-associated Bowel Microperforation in a Patient With Neuroblastoma.

scientific article

Biodistribution and dosimetry of (18)F-Meta Fluorobenzyl Guanidine (MFBG): A first-in-human PET-CT imaging study of patients with neuroendocrine malignancies.

scientific article published on 13 July 2017

Brain-sparing radiotherapy for neuroblastoma skull metastases

scientific article published on 01 June 2008

Camptothecin analogs (irinotecan or topotecan) plus high-dose cyclophosphamide as preparative regimens for antibody-based immunotherapy in resistant neuroblastoma

scientific article

Central nervous system germ cell tumors.

scientific article published on April 1998

Combination of bevacizumab, irinotecan, and temozolomide for refractory or relapsed neuroblastoma: Results of a phase II study

scientific article

Desmoplastic small round cell tumor 20 years after its discovery

scientific article published on January 2015

Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma

scientific article published in June 2010

Disialoganglioside GD2 and a novel tumor antigen: potential targets for immunotherapy of desmoplastic small round cell tumor

scientific article published on 01 December 2002

Dose-escalation is needed for gross disease in high-risk neuroblastoma.

scientific article published on 22 February 2018

EPT-08A PHASE I STUDY OF SINGLE-AGENT PERIFOSINE FOR RECURRENT/REFRACTORY PEDIATRIC CNS AND SOLID TUMORS.

scientific article published on 30 May 2016

Emerging treatment options for the treatment of neuroblastoma: potential role of perifosine

scientific article published on 02 March 2012

Enrichment of Targetable Mutations in the Relapsed Neuroblastoma Genome.

scientific article

Epigenetic Combination Therapy for Children With Secondary Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML) and Concurrent Solid Tumor Relapse

scientific article published on 29 May 2017

Failure of MIBG scan to detect metastases in SDHB-mutated pediatric metastatic pheochromocytoma

scientific article published on 14 April 2017

Feasibility of Administering High-Dose (131) I-MIBG Therapy to Children with High-Risk Neuroblastoma Without Lead-Lined Rooms.

scientific article

Five-day courses of irinotecan as palliative therapy for patients with neuroblastoma.

scientific article

Germline SDHA mutations in children and adults with cancer

scientific article published on 01 August 2018

High-dose carboplatin-irinotecan-temozolomide: treatment option for neuroblastoma resistant to topotecan

scientific article

High-dose cyclophosphamide inhibition of humoral immune response to murine monoclonal antibody 3F8 in neuroblastoma patients: broad implications for immunotherapy

scientific article published in April 2007

High-dose cyclophosphamide-irinotecan-vincristine for primary refractory neuroblastoma

scientific article published on 08 October 2010

Humanized 3F8 Anti-GD2 Monoclonal Antibody Dosing With Granulocyte-Macrophage Colony-Stimulating Factor in Patients With Resistant Neuroblastoma: A Phase 1 Clinical Trial

scientific article published on 01 December 2018

Hyperfractionated low-dose (21 Gy) radiotherapy for cranial skeletal metastases in patients with high-risk neuroblastoma.

scientific article published on 8 May 2009

Hypothyroidism after 131I-monoclonal antibody treatment of neuroblastoma

scientific article published in July 2010

Irinotecan plus temozolomide for relapsed or refractory neuroblastoma.

scientific article

Is Extended Sedation Necessary for Young Children Receiving High-Dose (131) I-MIBG Therapy?

scientific article published on 16 May 2016

Key role for myeloid cells: phase II results of anti-G(D2) antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma

scientific article

Lack of early bevacizumab-related skeletal radiographic changes in children with neuroblastoma

scientific article published on 01 February 2009

Lack of survival advantage with autologous stem-cell transplantation in high-risk neuroblastoma consolidated by anti-GD2 immunotherapy and isotretinoin

scientific article published on 26 November 2015

Liver involvement in neuroblastoma: the Memorial Sloan-Kettering Experience supports treatment reduction in young patients

scientific article published on 01 March 2006

Local Anesthesia With General Anesthesia for Pediatric Bone Marrow Procedures

scientific article published on 01 August 2019

Local Control With 21-Gy Radiation Therapy for High-Risk Neuroblastoma

scientific article published on 27 May 2016

Long-term Pulmonary Outcomes in Pediatric Survivors of High-risk Neuroblastoma.

scientific article published on 7 July 2017

Long-term complications in survivors of advanced stage neuroblastoma

scientific article published in September 2005

MYCN-amplified stage 2/3 neuroblastoma: excellent survival in the era of anti-GD2 immunotherapy.

scientific article published on 24 August 2017

Management of desmoplastic small round cell tumor

scientific article published on 14 September 2016

Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors

scientific article

Murine anti-GD2 monoclonal antibody 3F8 combined with granulocyte-macrophage colony-stimulating factor and 13-cis-retinoic acid in high-risk patients with stage 4 neuroblastoma in first remission

scientific article

Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor

scientific article published on 7 April 2015

Neuroblastoma in adolescents and adults: the Memorial Sloan-Kettering experience

scientific article published in December 2003

Norepinephrine Transporter as a Target for Imaging and Therapy.

scientific article published in September 2017

Nuclear war--doctor's responsibility

scientific article published on 01 May 1987

Oral (1-->3),(1-->4)-beta-D-glucan synergizes with antiganglioside GD2 monoclonal antibody 3F8 in the therapy of neuroblastoma

scientific article published on 01 May 2002

Osteochondroma in long-term survivors of high-risk neuroblastoma

scientific article published on 27 February 2015

Phase I trial of a bivalent gangliosides vaccine in combination with β-glucan for high-risk neuroblastoma in second or later remission

scientific article published on 11 February 2014

Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival.

scientific article published on 31 July 2017

Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma

scientific article published on 17 March 2011

Preliminary results of a phase I trial of prophylactic ethanol-lock administration to prevent mediport catheter-related bloodstream infections

scientific article published on October 2010

Prolonged progression-free survival after consolidating second or later remissions of neuroblastoma with Anti-GD2 immunotherapy and isotretinoin: a prospective Phase II study

scientific article published on 22 May 2015

Radiation Therapy to Sites of Metastatic Disease as Part of Consolidation in High-Risk Neuroblastoma: Can Long-term Control Be Achieved?

scientific article published on 9 January 2018

Radioimmunotargeting of human rhabdomyosarcoma using monoclonal antibody 8H9.

scientific article published on October 2005

Recurrent metastatic neuroblastoma followed by myelodysplastic syndrome: possible leukemogenic role of temozolomide

scientific article

Reduced risk of secondary leukemia with fewer cycles of dose-intensive induction chemotherapy in patients with neuroblastoma

scientific article

Reduced toxicity with intensity modulated radiation therapy (IMRT) for desmoplastic small round cell tumor (DSRCT): an update on the whole abdominopelvic radiation therapy (WAP-RT) experience

scientific article published on 17 October 2012

Reduced-Dose Radiation Therapy to the Primary Site is Effective for High-Risk Neuroblastoma: Results From a Prospective Trial

scientific article published on 11 February 2019

Reduction from seven to five cycles of intensive induction chemotherapy in children with high-risk neuroblastoma

scientific article

Renal Function Outcomes of High-risk Neuroblastoma Patients Undergoing Radiation Therapy.

scientific article published on 11 April 2017

Results of multimodal treatment for desmoplastic small round cell tumors.

scientific article

Rituximab therapy of lymphoma is enhanced by orally administered (1-->3),(1-->4)-D-beta-glucan

scientific article published in June 2005

Romiplostim for Immune Thrombocytopenia in Neuroblastoma Patients Receiving Chemotherapy

scientific article published on 01 May 2019

Salvage rates after progression of high-risk neuroblastoma with a soft tissue mass

scientific article published on 5 November 2015

Sensitivity of surveillance studies for detecting asymptomatic and unsuspected relapse of high-risk neuroblastoma.

scientific article published on 26 January 2009

Single-chain Fv-streptavidin substantially improved therapeutic index in multistep targeting directed at disialoganglioside GD2.

scientific article

Striking dichotomy in outcome of MYCN-amplified neuroblastoma in the contemporary era.

scientific article

Successful multifold dose escalation of anti-GD2 monoclonal antibody 3F8 in patients with neuroblastoma: a phase I study.

scientific article

Thiotepa-Based High-Dose Chemotherapy With Autologous Stem-Cell Rescue in Patients With Recurrent or Progressive CNS Germ Cell Tumors

scientific article published on 15 May 2004

Topotecan, thiotepa, and carboplatin for neuroblastoma: failure to prevent relapse in the central nervous system

scientific article published in February 2006

Trametinib-induced Left Ventricular Dysfunction in a Child With Relapsed Neuroblastoma.

scientific article published in August 2015

Transient sialoadenitis: a complication of 131I-metaiodobenzylguanidine therapy

scientific article published in June 2008

Treatment and outcome of adult-onset neuroblastoma.

scientific article published on 25 March 2018

Tumor lysis syndrome, neuroblastoma, and correlation between serum lactate dehydrogenase levels and MYCN-amplification

scientific article published in July 2003

Updates in the treatment of neuroblastoma

scientific article published on 01 January 2011

When overall survival fails to confirm event-free survival, should the latter be used to set the standard of care?

scientific article published on 17 November 2014

Whole neuraxis irradiation to address central nervous system relapse in high-risk neuroblastoma

scientific article published on 6 March 2010

Whole-body clearance kinetics and external dosimetry of 131I-3F8 monoclonal antibody for radioimmunotherapy of neuroblastoma.

scientific article

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