List of works - Alicja Kluczyk

A hexapeptide VTKFYF from C-terminal part of interleukin-1 receptor antagonist, an inhibitor of IL-1-IL-1 receptor interaction

scientific article published on March 1997

A new procedure for the synthesis of peptide-derived Amadori products on a solid support

Anti-IL-1 activity of peptide fragments of IL-1 family proteins

scientific article

Argireline: Needle‐Free Botox as Analytical Challenge

scientific article published in 2021

Comparison of modification sites in glycated crystallin in vitro and in vivo.

scientific article

Correction for "Synthesis of Mixed Opioid Affinity Cyclic Endomorphin-2 Analogues with Fluorinated Phenylalanines".

scientific article published on 9 May 2016

Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues

scientific article

Cyclic pentapeptide analogs based on endomorphin-2 structure: cyclization studies using liquid chromatography combined with on-line mass spectrometry and tandem mass spectrometry

scientific article published on 10 February 2014

Cyclodimerization of immunosuppressive fragment of HLA-DR molecule. Design, synthesis and ESI-MS/MS analysis.

scientific article published in August 2016

Derivatization of peptides for improved detection by mass spectrometry

Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold

scientific article

Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore

scientific article published on 17 September 2020

Detection of glycation sites in proteins by high-resolution mass spectrometry combined with isotopic labeling

scientific article

Dimeric analogs of immunosuppressive decapeptide fragment of ubiquitin

scientific article published on 25 May 2012

Drug evolution concept in drug design: 1. Hybridization method

scientific article (publication date: 30 December 2004)

Drug evolution concept in drug design: 2. Chimera method

scientific article

Drug evolution: p-aminobenzoic acid as a building block.

scientific article

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

scientific article published on 20 October 2011

Effect of neutral salts on the excited state proton transfer in the fluorescent probe anchored to the uncharged micelles

Electrospray ionization mass spectrometric analysis of complexes between peptide-derived Amadori products and borate ions

scientific article published in December 2009

Endomorphin-2 analogs containing modified tyrosines: Biological and theoretical investigation of the influence on conformation and pharmacological profile

scientific article published on 28 June 2019

Facile synthesis of deuterium-labeled denatonium cation and its application in the quantitative analysis of Bitrex by liquid chromatography-mass spectrometry.

scientific article published on 16 June 2015

Front Cover: Argireline: Needle‐Free Botox as Analytical Challenge (Chem. Biodiversity 3/2021)

scientific article published in 2021

Gas-phase fragmentation of oligoproline peptide ions lacking easily mobilizable protons.

scientific article published on 23 April 2013

Geometric changes around an N atom due to a urethane-type bis(tert-butoxycarbonyl) substituent

scientific article published on 13 December 2012

HLA-DQ7 beta(1) and beta(2) derived peptides as immunomodulators

scientific article

Hydrogen-deuterium exchange of α-carbon protons and fragmentation pathways in N-methylated glycine and alanine-containing peptides derivatized by quaternary ammonium salts

scientific article published on 01 June 2014

Immunomodulatory activity of oligopeptides related to interleukin 1 receptor antagonist sequence

scientific article published on 01 January 1997

Immunosuppressive activity of analogs of tripeptide Lys-Arg-Pro with D-amino acid residues

scientific article published on 01 January 1994

Impact of Micelle Ionic Electrical Double Layer Structure on the Excited State Protolytic Reaction in the Fluorescent Probe Bound to the Colloidal Nanoparticles

scientific article published on 06 June 2011

Microwave-assisted TFA cleavage of peptides from Merrifield resin

scientific article published in January 2010

Microwave-assisted18O labeling of Fmoc-protected amino acids

scientific article published on 06 August 2014

New method of peptide cleavage based on Edman degradation

scientific article

On the peptide-antipeptide interactions in interleukin-1 receptor system

scientific article published in January 2004

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation

scientific article published on 22 December 2020

Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues.

scientific article published on 13 March 2014

Pharmacological profile and molecular modeling of cyclic opioid analogs incorporating various phenylalanine derivatives

scientific article published on 15 May 2020

Preparation of novel deuterated cyclosporin A standards for quantitative LC-MS analysis.

scientific article published on 4 September 2017

RGD Peptides

RGD-Peptides and Some Immunological Problems

scholarly article published 2006

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

scientific article published in June 2015

Selective detection of carbohydrates and their peptide conjugates by ESI-MS using synthetic quaternary ammonium salt derivatives of phenylboronic acids

scientific article

Sensitive electrospray mass spectrometry analysis of one-bead-one-compound peptide libraries labeled by quaternary ammonium salts.

scientific article

Solid phase synthesis of peptides containing novel amino acids, substituted 3-benzimidazolealanines

scientific article

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

scientific article published on 05 December 2019

Synthesis and activity of opioid peptidomimetics with β2- and β3-amino acids

scientific article published on 3 August 2017

Synthesis and mass spectrometry analysis of quaternary cryptando-peptidic conjugates

scientific article published on 25 October 2015

Synthesis of linear and cyclic opioid-based peptide analogs containing multiple N-methylated amino acid residues

scientific article published on 24 September 2015

Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration

scientific article published on 12 December 2015

Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines

scientific article published on 3 April 2015

Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs.

scientific article published on 26 February 2016

Synthesis, receptor binding studies, optical spectroscopic and in silico structural characterization of morphiceptin analogs with cis-4-amino-L-proline residues.

scientific article published on 7 November 2017

The 5-azoniaspiro[4.4]nonyl group for improved MS peptide analysis: A novel non-fragmenting ionization tag for mass spectrometric sensitive sequencing of peptides

scientific article published on 15 July 2017

The efficient synthesis of isotopically labeled peptide-derived Amadori products and their characterization

scientific article published on 24 August 2010

The hydrogen-deuterium exchange at α-carbon atom in N,N,N-trialkylglycine residue: ESI-MS studies

scientific article published on 9 March 2012

The immunomodulatory diversity of the proteins of the transforming growth factor beta (TGF beta) family

The immunomodulatory diversity of the proteins of the transforming growth factor β (TGFβ) family

The immunosuppressive activity of peptide fragments of vaccinia virus C10L protein and a hypothesis on the role of this protein in the viral invasion

scientific article published on May 2002

The isotopic exchange of oxygen as a tool for detection of the glycation sites in proteins

scientific article published on 27 August 2011

The peptide molecular links between the central nervous and the immune systems.

scientific article

The problem of amino acid complementarity and antisense peptides.

scientific article

The search for inhibitors of interleukin-1 based on the sequence of interleukin-1 receptor antagonist

scientific article

The unusual hydrogen-deuterium exchange ofα-carbon protons inN-substituted glycine-containing peptides

scientific article published on 01 January 2014

The “two-headed” peptide inhibitors of interleukin-1 action

scientific article published on 01 September 2000

Tuftsin: on the 30-year anniversary of Victor Najjar's discovery

scientific article

Ubiquitin fragments: their known biological activities and putative roles

scientific article published on May 2010

List of works by Alicja Kluczyk

A hexapeptide VTKFYF from C-terminal part of interleukin-1 receptor antagonist, an inhibitor of IL-1-IL-1 receptor interaction

A new procedure for the synthesis of peptide-derived Amadori products on a solid support

Anti-IL-1 activity of peptide fragments of IL-1 family proteins

Argireline: Needle‐Free Botox as Analytical Challenge

Comparison of modification sites in glycated crystallin in vitro and in vivo.

Correction for "Synthesis of Mixed Opioid Affinity Cyclic Endomorphin-2 Analogues with Fluorinated Phenylalanines".

Cyclic mu-opioid receptor ligands containing multiple N-methylated amino acid residues

Cyclic pentapeptide analogs based on endomorphin-2 structure: cyclization studies using liquid chromatography combined with on-line mass spectrometry and tandem mass spectrometry

Cyclodimerization of immunosuppressive fragment of HLA-DR molecule. Design, synthesis and ESI-MS/MS analysis.

Derivatization of peptides for improved detection by mass spectrometry

Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold

Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore

Detection of glycation sites in proteins by high-resolution mass spectrometry combined with isotopic labeling

Dimeric analogs of immunosuppressive decapeptide fragment of ubiquitin

Drug evolution concept in drug design: 1. Hybridization method

Drug evolution concept in drug design: 2. Chimera method

Drug evolution: p-aminobenzoic acid as a building block.

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

Effect of neutral salts on the excited state proton transfer in the fluorescent probe anchored to the uncharged micelles

Electrospray ionization mass spectrometric analysis of complexes between peptide-derived Amadori products and borate ions

Endomorphin-2 analogs containing modified tyrosines: Biological and theoretical investigation of the influence on conformation and pharmacological profile

Facile synthesis of deuterium-labeled denatonium cation and its application in the quantitative analysis of Bitrex by liquid chromatography-mass spectrometry.

Front Cover: Argireline: Needle‐Free Botox as Analytical Challenge (Chem. Biodiversity 3/2021)

Gas-phase fragmentation of oligoproline peptide ions lacking easily mobilizable protons.

Geometric changes around an N atom due to a urethane-type bis(tert-butoxycarbonyl) substituent

HLA-DQ7 beta(1) and beta(2) derived peptides as immunomodulators

Hydrogen-deuterium exchange of α-carbon protons and fragmentation pathways in N-methylated glycine and alanine-containing peptides derivatized by quaternary ammonium salts

Immunomodulatory activity of oligopeptides related to interleukin 1 receptor antagonist sequence

Immunosuppressive activity of analogs of tripeptide Lys-Arg-Pro with D-amino acid residues

Impact of Micelle Ionic Electrical Double Layer Structure on the Excited State Protolytic Reaction in the Fluorescent Probe Bound to the Colloidal Nanoparticles

Microwave-assisted TFA cleavage of peptides from Merrifield resin

Microwave-assisted18O labeling of Fmoc-protected amino acids

New method of peptide cleavage based on Edman degradation

On the peptide-antipeptide interactions in interleukin-1 receptor system

Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation

Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues.

Pharmacological profile and molecular modeling of cyclic opioid analogs incorporating various phenylalanine derivatives

Preparation of novel deuterated cyclosporin A standards for quantitative LC-MS analysis.

RGD Peptides

RGD-Peptides and Some Immunological Problems

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

Selective detection of carbohydrates and their peptide conjugates by ESI-MS using synthetic quaternary ammonium salt derivatives of phenylboronic acids

Sensitive electrospray mass spectrometry analysis of one-bead-one-compound peptide libraries labeled by quaternary ammonium salts.

Solid phase synthesis of peptides containing novel amino acids, substituted 3-benzimidazolealanines

Synthesis and Pharmacological Evaluation of Hybrids Targeting Opioid and Neurokinin Receptors

Synthesis and activity of opioid peptidomimetics with β2- and β3-amino acids

Synthesis and mass spectrometry analysis of quaternary cryptando-peptidic conjugates

Synthesis of linear and cyclic opioid-based peptide analogs containing multiple N-methylated amino acid residues

Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration

Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines

Synthesis, biological evaluation and structural analysis of novel peripherally active morphiceptin analogs.

Synthesis, receptor binding studies, optical spectroscopic and in silico structural characterization of morphiceptin analogs with cis-4-amino-L-proline residues.

The 5-azoniaspiro[4.4]nonyl group for improved MS peptide analysis: A novel non-fragmenting ionization tag for mass spectrometric sensitive sequencing of peptides

The efficient synthesis of isotopically labeled peptide-derived Amadori products and their characterization

The hydrogen-deuterium exchange at α-carbon atom in N,N,N-trialkylglycine residue: ESI-MS studies

The immunomodulatory diversity of the proteins of the transforming growth factor beta (TGF beta) family

The immunomodulatory diversity of the proteins of the transforming growth factor β (TGFβ) family

The immunosuppressive activity of peptide fragments of vaccinia virus C10L protein and a hypothesis on the role of this protein in the viral invasion

The isotopic exchange of oxygen as a tool for detection of the glycation sites in proteins

The peptide molecular links between the central nervous and the immune systems.

The problem of amino acid complementarity and antisense peptides.

The search for inhibitors of interleukin-1 based on the sequence of interleukin-1 receptor antagonist

The unusual hydrogen-deuterium exchange ofα-carbon protons inN-substituted glycine-containing peptides

The “two-headed” peptide inhibitors of interleukin-1 action

Tuftsin: on the 30-year anniversary of Victor Najjar's discovery

Ubiquitin fragments: their known biological activities and putative roles