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List of works by Sanna-Kaisa Herukka

Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice

scientific article published in January 2003

Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients

scientific article published on 01 October 2018

Altered cerebrospinal fluid levels of amyloid β and amyloid precursor-like protein 1 peptides in Down's syndrome

scientific article published on 18 April 2014

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus

scientific article

An association study of 21 potential Alzheimer's disease risk genes in a Finnish population

scientific article published in January 2010

Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease

scientific article published in October 2014

Application of the PredictAD software tool to predict progression in patients with mild cognitive impairment

scientific article published on 6 December 2012

Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study

scientific article

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

BP180 Autoantibodies Target Different Epitopes in Multiple Sclerosis or Alzheimer's Disease than in Bullous Pemphigoid

scientific article published on 10 October 2018

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

scientific article published on 13 September 2019

Blood plasma IgG Fc glycans are significantly altered in Alzheimer's disease and progressive mild cognitive impairment

scientific article published on January 2014

CSF Abeta42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment

scientific article published in April 2005

CSF Abeta42, Tau and phosphorylated Tau, APOE epsilon4 allele and MCI type in progressive MCI.

scientific article published on 20 March 2006

CSF Abeta42, tau and phosphorylated tau correlate with medial temporal lobe atrophy.

scientific article published in May 2008

CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

scientific article published in July 2009

CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics

scientific article published on 05 June 2019

CSF biomarkers for the differential diagnosis of Alzheimer's disease: A large-scale international multicenter study.

scientific article

Cerebrospinal Fluid TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Patients with and without the C9ORF72 Hexanucleotide Expansion ⬇️

scientific article published on January 2016

Cerebrospinal Fluid and MRI Biomarkers in Neurodegenerative Diseases: A Retrospective Memory Clinic-Based Study

scientific article published on 16 April 2020

Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus

scientific article

Cerebrospinal fluid biomarkers for Alzheimer's disease in patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis with the C9ORF72 repeat expansion

scientific article published on 13 March 2015

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

scientific article

Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain

scientific article published in March 2009

Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers

scientific article

Clinical use of cerebrospinal fluid biomarkers in Alzheimer's disease

scientific article published in August 2012

Cognitive and Neuropsychiatric Symptom Differences in Early Stages of Alzheimer's Disease: Kuopio ALSOVA Study

scientific article

Comparing predictors of conversion to Alzheimer's disease using the disease state index

scientific article

Comparison between clinical diagnosis and CSF biomarkers of Alzheimer disease in elderly patients with late onset psychosis: Helsinki Old Age Psychosis Study (HOPS).

scientific article published on 15 April 2013

Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics

scientific article published in March 2016

Decreased plasma C-reactive protein levels in 4 allele carriers

Decreased plasma β-amyloid in the Alzheimer's disease APP A673T variant carriers

scientific article published on 26 May 2017

Differences in cortical thickness in healthy controls, subjects with mild cognitive impairment, and Alzheimer's disease patients: a longitudinal study

scientific article published in January 2010

Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia

scientific article

Disease State Fingerprint in Frontotemporal Degeneration with Reference to Alzheimer's Disease and Mild Cognitive Impairment ⬇️

scientific article published on January 1, 2013

Early diagnosis of Alzheimer's disease

scientific article published in January 2013

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach

scientific article published in January 2015

Evaluation of CSF cystatin C, beta-2-microglobulin, and VGF as diagnostic biomarkers of Alzheimer's disease using SRM

scholarly article by Malcolm A. Ward et al published July 2011 in Alzheimer's and Dementia

Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia

scientific article

Exploring Alzheimer molecular pathology in Down's syndrome cerebrospinal fluid

scientific article published on 27 June 2014

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients

scientific article published on 20 July 2007

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

scientific article published in January 2013

Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort

scientific article published on 24 June 2020

Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease

scientific article

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort

scientific article

Impact of a Clinical Decision Support Tool on Dementia Diagnostics in Memory Clinics: The PredictND Validation Study

scientific article published on 01 January 2019

Impact of a clinical decision support tool on prediction of progression in early-stage dementia: a prospective validation study

scientific article published on 20 March 2019

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

scientific article published on January 2017

Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer's Disease

scientific article published on 17 September 2016

Longitudinal changes of CSF biomarkers in Alzheimer's disease

scientific article published in January 2011

Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice

scientific article published on 01 December 2004

Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women

scientific article published on May 2016

Low Prevalence of Cancer in Patients with Frontotemporal Lobar Degeneration.

scientific article published in January 2018

Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients

scientific article published on 01 January 2019

Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease

scientific article published on 01 January 2020

Modified serpinA1 as risk marker for Parkinson's disease dementia: Analysis of baseline data

scientific article

Multicenter immunoassay validation of cerebrospinal fluid neurofilament light: a biomarker for neurodegeneration

scientific article published on 29 September 2016

Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS

article

Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus

scientific article published on 14 October 2016

Neurofilament ELISA validation

scientific article published on 24 October 2009

PTPR type Q in cerebrospinal fluid reflects ependymal cells dysfunction and is a potential biomarker for adult chronic hydrocephalus

scientific article published on 09 October 2020

Peripheral inflammatory markers and clinical correlations in patients with frontotemporal lobar degeneration with and without the C9orf72 repeat expansion

scientific article published on 26 September 2019

Pittsburgh compound B imaging and cerebrospinal fluid amyloid-β in a multicentre European memory clinic study

scientific article published on 07 July 2016

Plasma Neurofilament Light Chain (NF-L) Is a Prognostic Biomarker for Cortical Damage Evolution but Not for Cognitive Impairment or Epileptogenesis Following Experimental TBI

scholarly article

Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations

scientific article published on 23 October 2017

Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool

scientific article

Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus

scientific article published on 01 January 2019

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

scientific article published on 17 February 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

scientific article published on May 2015

Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers

scientific article published on 22 May 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

scientific article published on 27 March 2018

Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression

scientific article published in January 2014

Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers

article

Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia

scientific article

Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment

scientific article

S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies

scientific article published on 01 January 2018

Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy

scientific article published on 15 January 2020

Serum Neurofilament Light Chain Concentration Correlates with Infarct Volume but Not Prognosis in Acute Ischemic Stroke

scientific article published on 28 May 2019

Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis

scientific article published on 22 May 2020

Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders

scientific article published on 08 October 2019

Serum total TDP-43 levels are decreased in frontotemporal dementia patients with C9orf72 repeat expansion or concomitant motoneuron disease phenotype

scientific article published in 2022

Structural MRI in frontotemporal dementia: comparisons between hippocampal volumetry, tensor-based morphometry and voxel-based morphometry

scientific article

Subtle Cognitive Impairment and Alzheimer's Disease-Type Pathological Changes in Cerebrospinal Fluid are Common Among Neurologically Healthy Subjects

scientific article published in January 2018

Tau, S100B and NSE as Blood Biomarkers in Acute Cerebrovascular Events

scientific article published on 01 September 2020

The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

scientific article published on July 2011

The Association Between Frontotemporal Lobar Degeneration and Bullous Pemphigoid

scientific article published on 01 January 2018

The CERAD Neuropsychological Battery in Patients with Frontotemporal Lobar Degeneration

scientific article

The cerebrospinal fluid "Alzheimer profile": easily said, but what does it mean?

scientific article published on 8 April 2014

The effect of TOMM40 poly-T repeat lengths on age of onset and cerebrospinal fluid biomarkers in Finnish Alzheimer's disease patients

scientific article

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

scientific article published on 08 April 2017

The utility of α-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature

scientific article published on 28 August 2015

Threshold of heteroplasmic truncating MT-ATP6 mutation in reprogramming, Notch hyperactivation and motor neuron metabolism

scientific article published on 01 March 2022

Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging

scientific article published in August 2011

Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study

scientific article published on 14 October 2015

Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease

scientific article published on May 2016

Vitamin D supplementation and serum neurofilament light chain in interferon-beta-1b-treated MS patients

scientific article published on 23 July 2020

White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers

scientific article published on 21 November 2020

White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation

scientific article published on 15 March 2018

[11C]PIB PET Is Associated with the Brain Biopsy Amyloid-β Load in Subjects Examined for Normal Pressure Hydrocephalus

scientific article published on 01 January 2019

cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders

scientific article published on 25 August 2020

iTRAQ and multiple reaction monitoring as proteomic tools for biomarker search in cerebrospinal fluid of patients with Parkinson's disease dementia.

scientific article published in February 2012

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