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List of works by Laura Gatti

A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system

scientific article published on March 1999

A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cells

scientific article

A role for c-myc in DNA damage-induced apoptosis in a human TP53-mutant small-cell lung cancer cell line

scientific article

Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15

scientific article published on 22 October 2019

Antitumor activity of a novel homodimeric SMAC mimetic in ovarian carcinoma.

scientific article published on 27 November 2013

Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.

scientific article

Apoptosis induced by extracellular glutathione is mediated by H(2)O(2) production and DNA damage

scientific article

Axl molecular targeting counteracts aggressiveness but not platinum-resistance of ovarian carcinoma cells

scientific article

Cellular bases of the antitumor activity of a 7-substituted camptothecin in hormone-refractory human prostate carcinoma models

scientific article published in April 2003

Cellular pharmacology of cisplatin in relation to the expression of human copper transporter CTR1 in different pairs of cisplatin-sensitive and -resistant cells

scientific article published on July 2004

Cellular sensitivity to beta-diketonato complexes of ruthenium(III), chromium(III) and rhodium(III).

scientific article published on May 2006

Clinicopathological impact of ABCC1/MRP1 and ABCC4/MRP4 in epithelial ovarian carcinoma

scientific article published on 19 August 2013

Defining targets of modulation of human tumor cell response to cisplatin.

scientific article published on 8 January 2008

Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells.

scientific article published on July 2003

Differential outcome of MEK1/2 inhibitor-platinum combinations in platinum-sensitive and -resistant ovarian carcinoma cells

scientific article published on 24 February 2014

Drug Combinations with HDAC Inhibitors in Antitumor Therapy.

scientific article

Drug combinations with proteasome inhibitors in antitumor therapy

scientific article published on January 2013

Eradication of Ovarian Tumor Xenografts by Locoregional Administration of Targeted Immunotherapy

scientific article published on 01 September 2008

Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer

scientific article published in August 2002

FoxO-1 contributes to the efficacy of the combination of the XPO1 inhibitor selinexor and cisplatin in ovarian carcinoma preclinical models.

scientific article published on 16 November 2017

Gene expression profiles in the cellular response to a multinuclear platinum complex

scientific article published on April 2004

Global gene expression of fission yeast in response to cisplatin.

scientific article published in September 2004

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

scientific article

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals

scientific article

Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment.

scientific article published on 17 December 2013

Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin.

scientific article published on 31 December 2009

Mechanisms controlling sensitivity to platinum complexes: role of p53 and DNA mismatch repair.

scientific article

Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis

scientific article

Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy

scientific article published on 16 March 2019

Modulation of cell growth and cisplatin sensitivity by membrane gamma-glutamyltransferase in melanoma cells.

scientific article published on 22 August 2006

Modulation of sensitivity to antitumor agents by targeting the MAPK survival pathway.

scientific article published on January 2013

New mechanisms for old drugs: Insights into DNA-unrelated effects of platinum compounds and drug resistance determinants

scientific article published on 07 May 2015

Novel bis-platinum complexes endowed with an improved pharmacological profile

scientific article

Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction.

scientific article

Orchestration of DSB repair: a novel BRCA2 connection

scientific article published on 01 June 2015

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents.

scientific article published on 3 August 2017

PGE2 Is Crucial for the Generation of FAST Whole- Tumor-Antigens Loaded Dendritic Cells Suitable for Immunotherapy in Glioblastoma

scientific article published on 02 March 2020

PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

scientific article published on 20 August 2016

PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues

scientific article published in January 2015

Role of apoptosis and apoptosis-related genes in cellular response and antitumor efficacy of anthracyclines.

scientific article

Role of the Receptor Tyrosine Kinase Axl and its Targeting in Cancer Cells

scientific article published on 5 April 2016

Role of tyrosyl-DNA phosphodiesterase 1 and inter-players in regulation of tumor cell sensitivity to topoisomerase I inhibition.

scientific article published on 29 September 2011

Sensitization of tumor cells by targeting histone deacetylases

scientific article

Sensitization to gimatecan-induced apoptosis by tumor necrosis factor-related apoptosis inducing ligand in prostate carcinoma cells

scientific article published on 24 January 2006

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards

scientific article

Synergistic interaction between the novel histone deacetylase inhibitor ST2782 and the proteasome inhibitor bortezomib in platinum-sensitive and resistant ovarian carcinoma cells

scientific article

Targeting peptidyl-prolyl isomerase pin1 to inhibit tumor cell aggressiveness.

scientific article

Targeting the Akt kinase to modulate survival, invasiveness and drug resistance of cancer cells

scientific article published on January 2013

Targeting the invasive phenotype of cisplatin-resistant non-small cell lung cancer cells by a novel histone deacetylase inhibitor.

scientific article

The "stem" of chemoresistance.

scientific article

The ABC of glycosylation

scientific article published on 10 June 2010

The cellular basis of the efficacy of the trinuclear platinum complex BBR 3464 against cisplatin-resistant cells

scientific article published on 01 October 1999

The human homolog of fission yeast Rad17 is implicated in tumor growth

scientific article

Tyrosyl-DNA phosphodiesterase 1 targeting for modulation of camptothecin-based treatment.

scientific article published on January 2010

Ubiquitin-proteasome genes as targets for modulation of cisplatin sensitivity in fission yeast.

scientific article

Understanding the Pathophysiology of Cerebral Amyloid Angiopathy ⬇️

scientific article published on 13 May 2020

Vascular Remodeling in Moyamoya Angiopathy: From Peripheral Blood Mononuclear Cells to Endothelial Cells

scientific article published on 11 August 2020

Yeast mutants as a model system for identification of determinants of chemosensitivity.

scientific article

p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma

article

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