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List of works by James G. Prendergast

A cattle graph genome incorporating global breed diversity

scientific article published on 17 February 2022

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

article

A promoter-level mammalian expression atlas

scientific article

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma

scientific article

Abundant pleiotropy in human complex diseases and traits.

scientific article published on November 2011

Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.

scientific article published in December 2017

Arginine to Glutamine Variant in Olfactomedin Like 3 () Is a Candidate for Severe Goniodysgenesis and Glaucoma in the Border Collie Dog Breed

article

Chromatin structure and evolution in the human genome.

scientific article

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

scientific article

Detailed analysis of chick optic fissure closure reveals Netrin-1 as an essential mediator of epithelial fusion

scientific article published on 4 June 2019

Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait

scientific article published on 30 April 2019

Exome sequencing to detect rare variants associated with general cognitive ability: a pilot study.

scientific article published on 06 March 2015

Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes

scientific article

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

scientific article published on 30 March 2008

Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24.

scientific article published on 8 July 2007

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway

scientific article published on 21 October 2011

Germline susceptibility to colorectal cancer due to base-excision repair gene defects

scientific article

Graphia: A platform for the graph-based visualisation and analysis of high dimensional data

scientific article published on 25 July 2022

Homozygous loss-of-function variants in European cosmopolitan and isolate populations

scientific article

Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions

scientific article published on 25 November 2019

Linked Mutations at Adjacent Nucleotides Have Shaped Human Population Differentiation and Protein Evolution

scientific article published on 01 March 2019

Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies

scientific article

Loss-of-Function Mutations in the ALPL Gene Presenting with Adult Onset Osteoporosis and Low Serum Concentrations of Total Alkaline Phosphatase

scientific article published on 07 January 2020

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

scientific article

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

scientific article

Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer

scientific article

Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes

scientific article

Reply to Webb et al

Sequence-level mechanisms of human epigenome evolution.

scientific article

Sequencing and analysis of an Irish human genome

scientific article published on 7 September 2010

Sequencing illustrates the transcriptional response of Legionella pneumophila during infection and identifies seventy novel small non-coding RNAs

scientific article

Shared regulatory sites are abundant in the human genome and shed light on genome evolution and disease pleiotropy.

scientific article

Side effects: substantial non-neutral evolution flanking regulatory sites

scientific article

The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication.

scientific article

Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures

scientific article published on 17 February 2013

Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation

scientific article published on 17 January 2020

Whole-Genome Sequence Data Suggest Environmental Adaptation of Ethiopian Sheep Populations

scientific article published on 01 March 2021

Widespread signatures of recent selection linked to nucleosome positioning in the human lineage.

scientific article

hapbin: An Efficient Program for Performing Haplotype-Based Scans for Positive Selection in Large Genomic Datasets.

scientific article

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