List of works - Sílvia Socorro

5α-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth.

scientific article published on 9 August 2015

A cDNA for European sea bass (Dicentrachus labrax) 11beta-hydroxylase: gene expression during the thermosensitive period and gonadogenesis.

scientific article published on 7 September 2006

Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin

scientific article published on 4 September 2015

Androgen receptor is expressed in murine choroid plexus and downregulated by 5alpha-dihydrotestosterone in male and female mice

scientific article published on 18 November 2008

Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile ⬇️

scientific article published on August 16, 2012

Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes

scientific article published on 6 June 2015

Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis

scientific article published on 30 June 2011

Characterization of oligoadenylate synthetase-1 expression in rat mammary gland and prostate: effects of 17beta-estradiol on the regulation of OAS1g in both tissues

scientific journal article

Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes

scientific article published on 22 September 2013

Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function

scientific article

Effect of Prediabetes on Membrane Bicarbonate Transporters in Testis and Epididymis

scientific article published on 09 October 2013

Effect of extracellular calcium on regucalcin expression and cell viability in neoplastic and non-neoplastic human prostate cells.

scientific article published on 11 July 2015

Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells

scientific article published in February 2012

Endogenous Factors in the Recovery of Reproductive Function After Testicular Injury and Cancer.

scientific article

Estrogen Receptors α and β in Human Testis: Both Isoforms are Expressed

scientific article published in January 2009

Estrogen receptors alpha and beta in human testis: both isoforms are expressed

scientific article published on August 2009

Estrogenic regulation of testicular expression of stem cell factor and c-kit: implications in germ cell survival and male fertility

scientific article published on 10 May 2014

Estrogens down-regulate the stem cell factor (SCF)/c-KIT system in prostate cells: Evidence of antiproliferative and proapoptotic effects.

scientific article published on 16 November 2015

Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

scientific article published on 26 March 2013

Expression pattern of G protein-coupled receptor 30 in human seminiferous tubular cells.

scientific article

Glucose and glutamine handling in the Sertoli cells of transgenic rats overexpressing regucalcin: plasticity towards lactate production

scientific article published on 09 July 2018

High-energy diets may induce a pre-diabetic state altering testicular glycolytic metabolic profile and male reproductive parameters.

scientific article published on 14 March 2013

Histopathological and in vivo evidence of regucalcin as a protective molecule in mammary gland carcinogenesis.

scientific article published on 13 August 2014

Hormonal control of Sertoli cell metabolism regulates spermatogenesis ⬇️

scientific article published on July 20, 2012

Hormonal regulation of c-KIT receptor and its ligand: implications for human infertility?

scientific article

Identification of androgen receptor variants in testis from humans and other vertebrates.

scientific article published on 26 June 2012

Immunohistochemical detection of estrogen receptors in fish scales

scientific article published on 17 October 2008

Impact of Diabetes in Blood-Testis and Blood-Brain Barriers: Resemblances and Differences

In vitro cultured human Sertoli cells secrete high amounts of acetate that is stimulated by 17β-estradiol and suppressed by insulin deprivation.

scientific article published on 12 June 2012

Influence of 5α-dihydrotestosterone and 17β-estradiol on human Sertoli cells metabolism.

scientific article published on 4 August 2011

Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells culturedin vitro

scientific article published on 01 February 2012

Metabolic regulation is important for spermatogenesis.

scientific article

Metformin and male reproduction: effects on Sertoli cell metabolism

scientific article published on February 2014

Molecular basis of bicarbonate membrane transport in the male reproductive tract.

scientific article published on January 2013

Molecular cloning and sequence of gilthead sea bream (Sparus aurata) alpha-skeletal actin: tissue and developmental expression

scientific article

Molecular mechanisms beyond glucose transport in diabetes-related male infertility.

scientific article published on 21 January 2013

Natural Products as Protective Agents for Male Fertility

scientific article published in 2021

Novel FGFR1 mutations in Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism: evidence for the involvement of an alternatively spliced isoform

scientific article

Oestrogens as apoptosis regulators in mammalian testis: angels or devils?

scientific article published on 27 January 2015

Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer

scientific article

Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

scientific article published on 20 December 2013

Regucalcin counteracts tert-butyl hydroperoxide and cadmium-induced oxidative stress in rat testis

scientific article published on 25 April 2016

Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways

article

Regucalcin is broadly expressed in male reproductive tissues and is a new androgen-target gene in mammalian testis ⬇️

scientific article published in September 2011

Regucalcin is expressed in rat mammary gland and prostate and down-regulated by 17beta-estradiol.

scientific article published on 23 December 2007

Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones.

scientific article published on July 2009

Regucalcin, a calcium-binding protein with a role in male reproduction?

scientific article published in April 2012

Regucalcin, a calcium-binding protein, is a new target gene in human prostate cancer?

scientific article

Regulation of apoptotic signaling pathways by 5α-dihydrotestosterone and 17β-estradiol in immature rat Sertoli cells

scientific article

Revisiting prostate cancer metabolism: From metabolites to disease and therapy

scientific article published on 04 December 2020

STEAP1 expression in prostate cancer and its regulation by androgens.

scientific article

STEAP1 is over-expressed in breast cancer and down-regulated by 17beta-estradiol in MCF-7 cells and in the rat mammary gland.

scientific article

Six transmembrane epithelial antigen of the prostate 1 is down-regulated by sex hormones in prostate cells

scientific article

Sperm parameters and epididymis function in transgenic rats overexpressing the Ca2+-binding protein regucalcin: a hidden role for Ca2+ in sperm maturation?

scientific journal article

Structure, tissue distribution and estrogen regulation of splice variants of the sea bream estrogen receptor α gene.

scientific article published on 3 May 2012

Suppressed glycolytic metabolism in the prostate of transgenic rats overexpressing calcium-binding protein regucalcin underpins reduced cell proliferation.

scientific article

Sweet Cherry Extract Targets the Hallmarks of Cancer in Prostate Cells: Diminished Viability, Increased Apoptosis and Suppressed Glycolytic Metabolism

scientific article published on 11 September 2019

The Emerging Role of Regucalcin as a Tumor Suppressor: Facts and Views

scientific article

The SCF/c-KIT system in the male: Survival strategies in fertility and cancer

scientific article published on 30 October 2014

The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease ⬇️

scientific article published on March 22, 2013

The peculiarities of cancer cell metabolism: A route to metastasization and a target for therapy

scientific article published on 23 March 2019

The protective effect of regucalcin against radiation-induced damage in testicular cells

scientific article published on 9 September 2016

The stem cell factor (SCF)/c-KIT signalling in testis and prostate cancer

scientific article published on 27 June 2017

The stem cell factor (SCF)/c-KIT system in carcinogenesis of reproductive tissues: What does the hormonal regulation tell us?

scientific article

Transgenic overexpression of regucalcin leads to suppression of thapsigargin- and actinomycin D-induced apoptosis in the testis by modulation of apoptotic pathways.

scientific article

Transthyretin is up-regulated by sex hormones in mice liver.

scientific article published on 22 June 2008

Tyrosine kinase inhibitor imatinib modulates the viability and apoptosis of castrate-resistant prostate cancer cells dependently on the glycolytic environment

scientific article published on 31 December 2018

Use of poly(DL-lactide-ε-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly of the umbilical cord for promoting nerve regeneration in axonotmesis: in vitro and in vivo analysis.

scientific article

White tea as a promising antioxidant medium additive for sperm storage at room temperature: a comparative study with green tea.

scientific article published on 7 January 2014

List of works by Sílvia Socorro

5α-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth.

A cDNA for European sea bass (Dicentrachus labrax) 11beta-hydroxylase: gene expression during the thermosensitive period and gonadogenesis.

Aging-associated changes in oxidative stress, cell proliferation, and apoptosis are prevented in the prostate of transgenic rats overexpressing regucalcin

Androgen receptor is expressed in murine choroid plexus and downregulated by 5alpha-dihydrotestosterone in male and female mice

Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile ⬇️

Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes

Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis

Characterization of oligoadenylate synthetase-1 expression in rat mammary gland and prostate: effects of 17beta-estradiol on the regulation of OAS1g in both tissues

Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes

Diabetes, insulin-mediated glucose metabolism and Sertoli/blood-testis barrier function

Effect of Prediabetes on Membrane Bicarbonate Transporters in Testis and Epididymis

Effect of extracellular calcium on regucalcin expression and cell viability in neoplastic and non-neoplastic human prostate cells.

Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells

Endogenous Factors in the Recovery of Reproductive Function After Testicular Injury and Cancer.

Estrogen Receptors α and β in Human Testis: Both Isoforms are Expressed

Estrogen receptors alpha and beta in human testis: both isoforms are expressed

Estrogenic regulation of testicular expression of stem cell factor and c-kit: implications in germ cell survival and male fertility

Estrogens down-regulate the stem cell factor (SCF)/c-KIT system in prostate cells: Evidence of antiproliferative and proapoptotic effects.

Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells

Expression pattern of G protein-coupled receptor 30 in human seminiferous tubular cells.

Glucose and glutamine handling in the Sertoli cells of transgenic rats overexpressing regucalcin: plasticity towards lactate production

High-energy diets may induce a pre-diabetic state altering testicular glycolytic metabolic profile and male reproductive parameters.

Histopathological and in vivo evidence of regucalcin as a protective molecule in mammary gland carcinogenesis.

Hormonal control of Sertoli cell metabolism regulates spermatogenesis ⬇️

Hormonal regulation of c-KIT receptor and its ligand: implications for human infertility?

Identification of androgen receptor variants in testis from humans and other vertebrates.

Immunohistochemical detection of estrogen receptors in fish scales

Impact of Diabetes in Blood-Testis and Blood-Brain Barriers: Resemblances and Differences

In vitro cultured human Sertoli cells secrete high amounts of acetate that is stimulated by 17β-estradiol and suppressed by insulin deprivation.

Influence of 5α-dihydrotestosterone and 17β-estradiol on human Sertoli cells metabolism.

Metabolic modulation induced by oestradiol and DHT in immature rat Sertoli cells culturedin vitro

Metabolic regulation is important for spermatogenesis.

Metformin and male reproduction: effects on Sertoli cell metabolism

Molecular basis of bicarbonate membrane transport in the male reproductive tract.

Molecular cloning and sequence of gilthead sea bream (Sparus aurata) alpha-skeletal actin: tissue and developmental expression

Molecular mechanisms beyond glucose transport in diabetes-related male infertility.

Natural Products as Protective Agents for Male Fertility

Novel FGFR1 mutations in Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism: evidence for the involvement of an alternatively spliced isoform

Oestrogens as apoptosis regulators in mammalian testis: angels or devils?

Paradoxical and contradictory effects of imatinib in two cell line models of hormone-refractory prostate cancer

Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

Regucalcin counteracts tert-butyl hydroperoxide and cadmium-induced oxidative stress in rat testis

Regucalcin is an androgen-target gene in the rat prostate modulating cell-cycle and apoptotic pathways

Regucalcin is broadly expressed in male reproductive tissues and is a new androgen-target gene in mammalian testis ⬇️

Regucalcin is expressed in rat mammary gland and prostate and down-regulated by 17beta-estradiol.

Regucalcin is under-expressed in human breast and prostate cancers: Effect of sex steroid hormones.

Regucalcin, a calcium-binding protein with a role in male reproduction?

Regucalcin, a calcium-binding protein, is a new target gene in human prostate cancer?

Regulation of apoptotic signaling pathways by 5α-dihydrotestosterone and 17β-estradiol in immature rat Sertoli cells

Revisiting prostate cancer metabolism: From metabolites to disease and therapy

STEAP1 expression in prostate cancer and its regulation by androgens.

STEAP1 is over-expressed in breast cancer and down-regulated by 17beta-estradiol in MCF-7 cells and in the rat mammary gland.

Six transmembrane epithelial antigen of the prostate 1 is down-regulated by sex hormones in prostate cells

Sperm parameters and epididymis function in transgenic rats overexpressing the Ca2+-binding protein regucalcin: a hidden role for Ca2+ in sperm maturation?

Structure, tissue distribution and estrogen regulation of splice variants of the sea bream estrogen receptor α gene.

Suppressed glycolytic metabolism in the prostate of transgenic rats overexpressing calcium-binding protein regucalcin underpins reduced cell proliferation.

Sweet Cherry Extract Targets the Hallmarks of Cancer in Prostate Cells: Diminished Viability, Increased Apoptosis and Suppressed Glycolytic Metabolism

The Emerging Role of Regucalcin as a Tumor Suppressor: Facts and Views

The SCF/c-KIT system in the male: Survival strategies in fertility and cancer

The diverse roles of calcium-binding protein regucalcin in cell biology: from tissue expression and signalling to disease ⬇️

The peculiarities of cancer cell metabolism: A route to metastasization and a target for therapy

The protective effect of regucalcin against radiation-induced damage in testicular cells

The stem cell factor (SCF)/c-KIT signalling in testis and prostate cancer

The stem cell factor (SCF)/c-KIT system in carcinogenesis of reproductive tissues: What does the hormonal regulation tell us?

Transgenic overexpression of regucalcin leads to suppression of thapsigargin- and actinomycin D-induced apoptosis in the testis by modulation of apoptotic pathways.

Transthyretin is up-regulated by sex hormones in mice liver.

Tyrosine kinase inhibitor imatinib modulates the viability and apoptosis of castrate-resistant prostate cancer cells dependently on the glycolytic environment

Use of poly(DL-lactide-ε-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly of the umbilical cord for promoting nerve regeneration in axonotmesis: in vitro and in vivo analysis.

White tea as a promising antioxidant medium additive for sperm storage at room temperature: a comparative study with green tea.