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List of works by Sheila E. Francis

A cardinal role for cathepsin d in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci.

scientific article

A cell kinetic analysis of human umbilical vein endothelial cells

scientific article published in December 2000

A central role for monocytes in Toll-like receptor-mediated activation of the vasculature

scientific article published in September 2009

A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study

scientific article

A novel mouse model of in situ stenting.

scientific article published on January 2010

A potential pharmacogenomic strategy for anticoagulant treatment in non-ST elevation acute coronary syndromes: the role of interleukin-1 receptor antagonist genotype.

scientific article published on February 2005

A role for caspase-1 in serum withdrawal-induced apoptosis of endothelial cells

scientific article published in October 2003

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

scientific article published on 15 November 2019

Action of intracellular IL-1Ra (Type 1) is independent of the IL-1 intracellular signalling pathway

scientific article

Alterations in c-fos expression, cell proliferation and apoptosis in pressure distended human saphenous vein

scientific article published in November 1999

Bone mineral metabolism parameters and urinary albumin excretion in a representative US population sample

scientific article

Brain inflammation is induced by co-morbidities and risk factors for stroke

scientific article

Central Roles of α 5 β 1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies

scientific article published in June 2002

Circulating endothelial cells in whole blood donations and the effect of leucodepletion

scientific article published in February 2010

Comparison of response to injury in organ culture of human saphenous vein and internal mammary artery

scientific article published in June 1993

Dietary Phosphate Modulates Atherogenesis and Insulin Resistance in Apolipoprotein E Knockout Mice—Brief Report

scientific article published in September 2011

Differential gene expression in coronary arteries from patients presenting with ischemic heart disease: further evidence for the inflammatory basis of atherosclerosis

scientific article published in September 2005

Distension produces medial but not endothelial damage in porcine internal mammary artery.

scientific article published in April 1995

Enhanced macrophage tribbles-1 expression in murine experimental atherosclerosis

scientific article

Genetic experimental preparations for studying atherosclerosis.

scientific article published on January 2014

Heparin and neointimal thickening in an organ culture of human saphenous vein

scientific article published in March 1992

Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

scientific article

Interleukin-1 in Myocardium and Coronary Arteries of Patients with Dilated Cardiomyopathy

scientific article published in February 1998

Interleukin-1 receptor antagonist (IL-1RN) genotype modulates the replicative capacity of human endothelial cells

scientific article published on 22 May 2003

Interleukin-1 receptor antagonist (IL-1ra) modulates endothelial cell proliferation

scientific article published on 20 February 2008

Interleukin-1 receptor antagonist alters the response to vessel wall injury in a porcine coronary artery model

scientific article published in December 2005

Interleukin-1beta and signaling of interleukin-1 in vascular wall and circulating cells modulates the extent of neointima formation in mice.

scientific article

Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice

scientific article published on 23 July 2018

LDL uptake by monocytes in response to inflammation is MAPK dependent but independent of tribbles protein expression

scientific article

Loss of Tribbles pseudokinase-3 promotes Akt-driven tumorigenesis via FOXO inactivation.

scientific article published on 29 August 2014

Measurement of plasma von Willebrand factor in acute coronary syndromes and the influence of ABO blood group status

scientific article published in November 2004

Mechanistic links between acute respiratory tract infections and acute coronary syndromes.

scientific article

Methylenetetrahydrofolate reductase polymorphism (C-677T) and coronary artery disease

scientific article published on 01 September 1998

Microbubble-enhanced ultrasound for vascular gene delivery

scientific article published in December 2000

Myeloid Tribbles 1 induces early atherosclerosis via enhanced foam cell expansion

scientific article published on 30 October 2019

Neutrophil elastase promotes interleukin-1β secretion from human coronary endothelium.

scientific article

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium

scientific article published on 10 January 2020

No evidence for cardiac dysfunction in Kif6 mutant mice

scientific article

P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells

scientific article

Platelet P2Y 12 Receptor Influences the Vessel Wall Response to Arterial Injury and Thrombosis

scientific article published on 22 December 2008

Protective role for properdin in progression of experimental murine atherosclerosis.

scientific article published on 25 March 2014

Requirement of JNK1 for endothelial cell injury in atherogenesis.

scientific article

Role of Animal Models in Coronary Stenting

scientific article published on 11 August 2015

Serum-Free organ culture of vascular tissues

scientific article published in November 1992

Streptococcus pneumoniaeworsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα

scientific article published on 14 April 2014

TGFβ is active, and correlates with activators of TGFβ, following porcine coronary angioplasty

scientific article published in April 2001

TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice

scientific article published on 28 January 2011

TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling.

scientific article published on 18 April 2015

Targeting and delivery of bactericide to adsorbed oral bacteria by use of proteoliposomes

scientific article published in April 1993

Temporal and spatial distribution of interleukin-1β in balloon injured porcine coronary arteries

scientific article published in October 1999

Temporal interleukin-1beta secretion from primary human peripheral blood monocytes by P2X7-independent and P2X7-dependent mechanisms.

scientific article

The characterisation of liposomes with covalently attached proteins

scientific article published in January 1989

The effect of surface-bound protein on the permeability of proteoliposomes

scientific article published in February 1991

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action.

scientific article published on 6 April 2013

The role of complement in the development and manifestation of murine atherogenic inflammation: novel avenues.

scientific article

Ticagrelor effectively and reversibly blocks murine platelet P2Y12-mediated thrombosis and demonstrates a requirement for sustained P2Y12 inhibition to prevent subsequent neointima.

scientific article

Transforming growth factor-beta1 gene polymorphisms and coronary artery disease

scientific article published on 01 December 1998

Tribbles in inflammation

scientific article

Tribbles-2 is a novel regulator of inflammatory activation of monocytes

scientific article published on 24 October 2008

Ultrasound-enhanced transgene expression in vascular cells is not dependent upon cavitation-induced free radicals.

scientific article published in October 2003

Ultrasound-mediated delivery of TIMP-3 plasmid DNA into saphenous vein leads to increased lumen size in a porcine interposition graft model

scientific article published in July 2005

Vessel wall, not platelet, P2Y12 potentiates early atherogenesis

scientific article published on 07 February 2014

Vitamin D deficiency and exogenous vitamin D excess similarly increase diffuse atherosclerotic calcification in apolipoprotein E knockout mice

scientific article

miRNA-21 is dysregulated in response to vein grafting in multiple models and genetic ablation in mice attenuates neointima formation

scientific article published on 25 March 2013

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