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List of works by David K. Finlay

A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression

article

AMPKα1: a glucose sensor that controls CD8 T-cell memory

scientific article published on 13 February 2013

Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

scientific article

Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation

scientific article published on 03 May 2019

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice.

scientific article published on 14 June 2018

Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.

scientific article published on December 2005

Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism

scientific article published on 02 May 2018

Competition for nutrients and its role in controlling immune responses

article

De novo polyamine synthesis supports metabolic and functional responses in activated murine Natural Killer cells

scientific article published on 18 September 2020

Diverse Immunoregulatory Roles of Oxysterols-The Oxidized Cholesterol Metabolites

scientific article published on 28 September 2020

Functional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226.

scientific article published on 6 April 2006

Glucose represses dendritic cell-induced T cell responses

scientific article

Glucose, glycolysis and lymphocyte responses

scientific article published on 07 August 2015

IRF4 links antigen affinity to CD8+ T-cell metabolism.

scientific article published on 29 October 2013

Immunometabolism and natural killer cell responses

scientific article published on 01 May 2019

Immunometabolism: Cellular Metabolism Turns Immune Regulator

scientific article

Inhibitors of the NMDA-Nitric Oxide Signaling Pathway Protect Against Neuronal Atrophy and Synapse Loss Provoked by l-alpha Aminoadipic Acid-treated Astrocytes

scientific article published on 27 September 2018

Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions

scientific article published in 2024

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

scientific article published on January 2010

Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells

scientific article published on 12 February 2016

Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses

scientific article published on 19 August 2020

Metabolic regulation of immune responses: therapeutic opportunities

scientific article published on June 2016

Metabolic regulation of natural killer cells

scientific article published on 03 August 2015

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

article

Metabolic requirements of NK cells during the acute response against retroviral infection

scientific article published on 10 September 2021

Metabolism, migration and memory in cytotoxic T cells ⬇️

scientific article published on January 14, 2011

Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages

scientific article published on 05 March 2021

N-myristoylation of AMPK controls T cell inflammatory function

scientific article published on 01 March 2019

Notch-induced T cell development requires phosphoinositide-dependent kinase 1.

scientific article published on 28 June 2007

Nutrient sensing, signal transduction and immune responses.

scientific article published on 24 September 2016

Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses

scientific article published on 10 May 2019

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

scientific article published on 26 November 2012

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

scientific article

Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation

scientific article published on 24 August 2009

Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration

scientific article published on January 2010

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

scientific article published on 5 October 2009

Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

scientific article

Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases ⬇️

scientific article published on 07 August 2012

Srebp-controlled glucose metabolism is essential for NK cell functional responses

scientific article published on 18 September 2017

Starved human T lymphocytes keep fighting

scientific article published on 01 September 2015

Sugar or Fat?-Metabolic Requirements for Immunity to Viral Infections

scientific article published on 16 October 2017

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

scholarly article

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

scientific article

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells

scientific article

The Coordination of T-cell Function by Serine/Threonine Kinases ⬇️

scientific article published on January 1, 2011

What Fuels Natural Killers? Metabolism and NK Cell Responses

scientific article

mTORC1 regulates CD8+ T-cell glucose metabolism and function independently of PI3K and PKB ⬇️

scientific article published on April 1, 2013

mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function.

scientific article

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