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List of works by Dong-Seok Yim

A Population Pharmacokinetic and Pharmacodynamic Model of CKD-519

scientific article published on 19 June 2020

A novel placement method of the Bravo wireless pH monitoring capsule for measuring intragastric pH.

scientific article published on 23 July 2008

A phase I study of everolimus and CHOP in newly diagnosed peripheral T-cell lymphomas

scientific article

A population pharmacokinetic-pharmacodynamic model for simvastatin that predicts low-density lipoprotein-cholesterol reduction in patients with primary hyperlipidaemia

scientific article published on 14 May 2011

Application of Pharmacometrics in Pharmacotherapy: Open-Source Software for Vancomycin Therapeutic Drug Management.

scientific article published on 9 May 2019

Assay of omeprazole and omeprazole sulfone by semi-microcolumn liquid chromatography with mixed-function precolumn.

scientific article

Author's response to letter to the editor on: Physiologically based pharmacokinetic predictions of intestinal BCRP-mediated effect of telmisartan on the pharmacokinetics of rosuvastatin in humans

scientific article

Bortezomib pharmacokinetics in tumor response and peripheral neuropathy in multiple myeloma patients receiving bortezomib-containing therapy

scientific article published on 20 April 2017

CYP1A2 activity as a risk factor for bladder cancer

scientific article

Combined effect of GSTM1, GSTT1, and COMT genotypes in individual breast cancer risk

scientific article published in November 2004

Comparison of oral absorption models for pregabalin: usefulness of transit compartment model

scientific article published on 7 December 2016

Comparison of parametric and bootstrap method in bioequivalence test.

scientific article published on 31 October 2009

Contribution of Trough Concentration Data in the Evaluation of Multiple-Dose Pharmacokinetics for Drugs with Delayed Distributional Equilibrium and Long Half-Life

scientific article published on 25 February 2020

Drug-drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer.

scientific article published on 30 March 2017

Early non-steady-state population pharmacokinetics of oral cyclosporine in renal transplant recipients

scientific article

Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19.

scientific article published in April 2001

Efficacies of vancomycin, arbekacin, and gentamicin alone or in combination against methicillin-resistant Staphylococcus aureus in an in vitro infective endocarditis model.

scientific article published on December 2003

Erythrocyte thiopurine methyltransferase activity in a Korean population

scientific article published in November 1996

Exposure-response model for sibutramine and placebo: suggestion for application to long-term weight-control drug development

scientific article

Human immune response to a Pseudomonas aeruginosa outer membrane protein vaccine

scientific article published on 01 January 1999

Human microdosing and mice xenograft data of AGM-130 applied to estimate efficacious doses in patients.

scientific article

Immunogenicity and Safety of Trivalent Split Influenza Vaccine in Healthy Korean Adults with Low Pre-Existing Antibody Levels: An Open Phase I Trial.

scientific article

Leveraging prior quantitative knowledge to guide drug development decisions and regulatory science recommendations: impact of FDA pharmacometrics during 2004-2006.

scientific article

Mixed-effect circadian rhythm model for human erythrocyte acetylcholinesterase activity--application to the proof of concept of cholinesterase inhibition by acorn extract in healthy subjects with galantamine as positive control

scientific article published on 30 December 2011

Model-based adaptive phase I trial design of post-transplant decitabine maintenance in myelodysplastic syndrome

scientific article

Modeling of the parathyroid hormone response after calcium intake in healthy subjects

scientific article

Omeprazole hydroxylation is inhibited by a single dose of moclobemide in homozygotic EM genotype for CYP2C19

scientific article published on April 2002

Omeprazole limited sampling strategies to predict area under the concentration-time curve ratios: implications for cytochrome P450 2C19 and 3A phenotyping

scientific article

Overestimation of Vancomycin Clearance by the Linear Regression Formula in Rodvold's Report: Why?

scientific article published on March 2014

Pharmacokinetic-pharmacodynamic analysis to evaluate the effect of moxifloxacin on QT interval prolongation in healthy Korean male subjects

scientific article

Pharmacokinetic-pharmacodynamic model of fimasartan applied to predict the influence of a high fat diet on its blood pressure-lowering effect in healthy subjects

scientific article

Phase 1 trial of S-1 in combination with sorafenib for patients with advanced hepatocellular carcinoma

scientific article

Phase I study of intraperitoneal irinotecan in patients with gastric adenocarcinoma with peritoneal seeding

scientific article published on 6 March 2010

Phase II trial of capecitabine and everolimus (RAD001) combination in refractory gastric cancer patients

scientific article published on 7 September 2013

Physiologically-based pharmacokinetic predictions of intestinal BCRP-mediated drug interactions of rosuvastatin in Koreans.

scientific article published on 25 April 2018

Population pharmacokinetic analysis and simulation of the time-concentration profile of etanercept in pediatric patients with juvenile rheumatoid arthritis

scientific article published on 01 March 2005

Population pharmacokinetic analysis of colistin in burn patients.

scientific article published on 25 February 2013

Population pharmacokinetic analysis of piperacillin in burn patients

scientific article

Population pharmacokinetic/pharmacodynamic modeling of clopidogrel in Korean healthy volunteers and stroke patients.

scientific article

Population pharmacokinetics of CPT-11 (irinotecan) in gastric cancer patients with peritoneal seeding after its intraperitoneal administration

scientific article published on 9 September 2010

Population pharmacokinetics of arbekacin in burn patients

scientific article published in June 2008

Population pharmacokinetics of intravenous itraconazole in patients with persistent neutropenic fever.

scientific article published on June 2009

Potency and plasma protein binding of drugs in vitro-a potentially misleading pair for predicting in vivo efficacious concentrations in humans

scientific article published on 25 June 2019

Predicting human pharmacokinetics from preclinical data: absorption

scientific article published on 21 September 2020

Quantitative Prediction of Human Pharmacokinetics and Pharmacodynamics of CKD519, a Potent Inhibitor of Cholesteryl Ester Transfer Protein (CETP)

scientific article published on 15 July 2019

Randomised phase II trial of docetaxel and sunitinib in patients with metastatic gastric cancer who were previously treated with fluoropyrimidine and platinum.

scientific article published on 29 March 2012

Relationship between the Val158Met polymorphism of catechol O-methyl transferase and breast cancer

scientific article published on 01 June 2001

SAFETY OF A CRM197-CONJUGATED HAEMOPHILUS INFLUENZAE TYPE B VACCINE IN KOREAN CHILDREN.

scientific article

Safety and immunogenicity of a single intramuscular dose of a tetanus-diphtheria toxoid (Td) vaccine (BR-TD-1001) in healthy Korean adult subjects

scientific article published on 19 June 2015

Saturable human neopterin response to interferon-α assessed by a pharmacokinetic-pharmacodynamic model

scientific article published on 2 October 2013

Simulation of PET scan timings for receptor occupancy studies of CNS drugs: a simple fixed-time design performed as well as scattered time point designs

scientific article published on 9 September 2015

Simulation of the AUC changes after generic substitution in patients.

scientific article published on 28 February 2009

Teicoplanin dosing strategy for treatment of Staphylococcus aureus in Korean patients with neutropenic fever ⬇️

scientific article

The effects of moxifloxacin on QTc interval in healthy Korean male subjects

scientific article

The safety and pharmacokinetics of cyanidin-3-glucoside after 2-week administration of black bean seed coat extract in healthy subjects.

scientific article

Therapeutic drug monitoring and safety of intravenous voriconazole formulated with sulfobutylether β-cyclodextrin in haematological patients with renal impairment.

scientific article published on 21 June 2016

Three-Dimensional Heart Model-Based Screening of Proarrhythmic Potential by in silico Simulation of Action Potential and Electrocardiograms

scientific article published on 04 September 2019

Use of a Target-Mediated Drug Disposition Model to Predict the Human Pharmacokinetics and Target Occupancy of GC1118, an Anti-epidermal Growth Factor Receptor Antibody

scientific article published on 16 September 2016

Usefulness of Bnet, a Simple Linear Metric in Discerning Torsades De Pointes Risks in 28 CiPA Drugs

scientific article published on 26 November 2019

Validation of a liquid chromatography-triple quadrupole mass spectrometric method for the determination of 5-nitro-5'-hydroxy-indirubin-3'-oxime (AGM-130) in human plasma and its application to microdose clinical trial

scientific article published on 2 July 2015

Voriconazole-related severe adverse events: clinical application of therapeutic drug monitoring in Korean patients

scientific article published on 9 August 2011

What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing

scientific article published on 09 January 2019

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