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List of works by Loretta Tuosto

A new tripeptide, Pol 509, influences biochemical events associated with antigen presentation efficiency of PPD-specific EBV-B cells

scientific article published on January 1993

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28.

scientific article published on 14 March 2018

A novel association between filamin A and NF-κB inducing kinase couples CD28 to inhibitor of NF-κB kinase α and NF-κB activation

scientific article published on 26 January 2011

Analysis of susceptibility of mature human T lymphocytes to dexamethasone-induced apoptosis

scientific article published on May 1994

CD28 Autonomous Signaling Up-Regulates C-Myc Expression and Promotes Glycolysis Enabling Inflammatory T Cell Responses in Multiple Sclerosis

scientific article published on 11 June 2019

CD28 Individual Signaling Up-regulates Human IL-17A Expression by Promoting the Recruitment of RelA/NF-κB and STAT3 Transcription Factors on the Proximal Promoter

scientific article published on 24 April 2019

CD28 affects the earliest signaling events generated by TCR engagement

scientific article published in July 1998

CD28 between tolerance and autoimmunity: the side effects of animal models.

scientific article published on 30 May 2018

CD28 costimulatory signals in T lymphocyte activation: Emerging functions beyond a qualitative and quantitative support to TCR signalling

scientific article published on 4 March 2016

CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.

scholarly article

CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse

scientific article published on 22 October 2006

CD28 ligation in the absence of TCR stimulation up-regulates IL-17A and pro-inflammatory cytokines in relapsing-remitting multiple sclerosis T lymphocytes

scientific article published on 8 January 2014

Different regions of the N-terminal domains of HLA-DR1 influence recognition of individual peptide-DR1 complexes

scientific article published on August 1994

Differential susceptibility to monomeric HIV gp120-mediated apoptosis in antigen-activated CD4+ T cell populations

scientific article

Hypervariable region 1 variant acting as TCR antagonist affects hepatitis C virus-specific CD4+ T cell repertoire by favoring CD95-mediated apoptosis.

scientific article published on 27 May 2005

ISA-2011B, a Phosphatidylinositol 4-Phosphate 5-Kinase α Inhibitor, Impairs CD28-Dependent Costimulatory and Pro-inflammatory Signals in Human T Lymphocytes

scientific article

Ligation of either CD2 or CD28 rescues CD4+ T cells from HIV-gp120-induced apoptosis

scientific article

Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-kappaB activation

scientific article published in September 2000

NF-κB family of transcription factors: biochemical players of CD28 co-stimulation.

scientific article published on 21 September 2010

Natural killer clones recognize specific soluble HLA class I molecules

scientific article published on 01 March 1996

Phosphatidylinositol 4-Phosphate 5-Kinase β Controls Recruitment of Lipid Rafts into the Immunological Synapse

scientific article

Phosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell Activation

scientific article

Phosphatidylinositol 4-phosphate 5-kinase α activation critically contributes to CD28-dependent signaling responses.

scientific article

Phosphatidylinositol 4-phosphate 5-kinase α and Vav1 mutual cooperation in CD28-mediated actin remodeling and signaling functions

scientific article published on 24 December 2014

Proximal changes in signal transduction that modify CD8+ T cell responsiveness in vivo

scientific article published in September 2003

Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering

scientific article published on November 1997

RelA/NF-kappaB recruitment on the bax gene promoter antagonizes p73-dependent apoptosis in costimulated T cells.

scientific article published on 23 November 2007

Role of alpha-synuclein in autophagy modulation of primary human T lymphocytes

scientific article

T Helper Cells: The Modulators of Inflammation in Multiple Sclerosis

scientific article published on 19 February 2020

The Impact of the 'Mis-Peptidome' on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response

scientific article published on 17 December 2020

The activation of Csk by CD4 interferes with TCR-mediated activatory signaling

scientific article published in September 2003

The cancer-associated K351N mutation affects the ubiquitination and the translocation to mitochondria of p53 protein.

scientific article published on 27 September 2011

The multifaceted role of PIP2 in leukocyte biology.

scientific article published on 12 August 2015

Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells

scientific article

Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1.

scientific article published in February 2002

Vav exchange factor counteracts the HIV-1 Nef-mediated decrease of plasma membrane GM1 and NF-AT activity in T cells

scientific article published in August 2003

p53 death signal is mainly mediated by Nuc1(EndoG) in the yeast Saccharomyces cerevisiae

scientific article published on 12 August 2013

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