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List of works by Robert H. Howland

"Evidence" and the treatment of alcohol use disorder

scientific article published on May 2015

"I Want a New Drug": Exercise as a Pharmacological Therapy

scientific article published in August 2015

A Benefit-Risk Assessment of Agomelatine in the Treatment of Major Depression

scientific article published on September 1, 2011

A Critical Evaluation of the Cardiac Toxicity of Citalopram: Part 1

article

A Critical Evaluation of the Cardiac Toxicity of Citalopram: Part 2

article

A Question About the Potential Cardiac Toxicity of Escitalopram

article

A Question About the Safety of Buprenorphine/Naloxone and Benzodiazepine Drugs

scientific article published on December 2015

A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression

scientific article

A comprehensive review of cyclothymic disorder

scientific article

A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression.

scientific article published on September 2005

A pilot study of vagus nerve stimulation (VNS) for treatment-resistant anxiety disorders

scientific article

A proposed system for classifying psychotropic drugs

scientific article

A prospective test of criteria for response, remission, relapse, recovery, and recurrence in depressed patients treated with cognitive behavior therapy

scientific article published on 01 April 1997

A “Glucose Eater” Drug as a Therapeutic Agent in Psychiatry ⬇️

scientific article published on August 16, 2013

Adolescent depression: assessment and treatment

scientific article published in July 2009

Age of onset in chronic major depression: relation to demographic and clinical variables, family history, and treatment response

scientific article published on 01 October 1999

Agomelatine: a novel atypical antidepressant

scientific article

Alternative Drug Therapies for Dementia ⬇️

scientific article published on April 27, 2011

An overview of seasonal affective disorder and its treatment options

scientific article

Anticonvulsant drug therapies.

scientific article

Antidepressant Drugs and Infectious Disease ⬇️

scientific article published on July 1, 2013

Antidepressant Drugs and the Risk of Intracranial Bleeding: Parsing an Observational Study

scientific article published in February 2016

Antidepressant Medication and Pregnancy: Time for Randomized Controlled Trials ⬇️

scientific article published on January 18, 2013

Antidepressant, Antipsychotic, and Hallucinogen Drugs for the Treatment of Psychiatric Disorders: A Convergence at the Serotonin-2A Receptor

scientific article published in July 2016

Are Generic Medications Safe and Effective?

scientific article published on 01 March 2010

Aspergillus, angiogenesis, and obesity: the story behind beloranib

scientific article

Association Between Vitamin D Status and Cognitive Decline

scientific article published on 01 June 2016

Atypical antipsychotics are not all alike: side effects and risk assessment

scientific article published on 4 September 2014

Atypical antipsychotics: special formulations for acute agitation

scientific article

Baclofen for the Treatment of Alcohol Dependence

article

Barriers to community treatment of patients with dual diagnoses

scientific article published in October 1990

Biochemical Effects of Antidepressant Augmentation

article

Biochemical and clinical effects of buspirone augmentation.

scientific article published in June 1994

Biological studies of dysthymia.

scientific article published on August 1991

Bipolar disorder associated with primary generalised epilepsy

scientific article

Borderline personality disorder: inpatient psychiatric nursing management.

scientific article published in May 2009

Brexpiprazole: another multipurpose antipsychotic drug?

scientific article published on April 2015

Buspirone: Back to the Future

scientific article

Can Declining Rates of Dementia Be Explained by the Increased and Widespread Use of Psychotropic Medications?

scientific article

Can a Bug in the Gut Act Like a Drug in the Brain?

scientific article published in October 2015

Cardiovascular Health and Cognitive Decline

scientific article published on 01 December 2018

Caregivers of loved ones with Alzheimer's disease

scientific article published in November 2009

Challenges in the diagnosis & treatment of bipolar depression--Part 1: assessment.

scientific article

Chlorpromazine and obsessive-compulsive symptoms

scientific article published on November 1996

Chronic depression: medication (nefazodone) or psychotherapy (CBASP) is effective when the other is not.

scientific article published in May 2005

Chronic forms of major depression are still undertreated in the 21st century: systematic assessment of 801 patients presenting for treatment

scientific article

Citalopram, QTc interval prolongation, and torsade de pointes. How should we apply the recent FDA ruling?

scientific article published on 27 June 2012

Clinical features and functioning of patients with minor depression

scientific article published on 21 August 2008

Clinical implications of chirality and stereochemistry in psychopharmacology

scientific article published on August 2009

Cognitive outcome after ventral capsule/ventral striatum stimulation for treatment-resistant major depression

scientific article published on 22 September 2016

Commentary: The Need to Guard Against Pharmaceutical Industry Influence

article

Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: results of the BRITE-MD study

scientific article

Comparison of DSM-III-R chronic major depression and major depression superimposed on dysthymia (double depression): validity of the distinction

scientific article published in August 2000

Concern for truth: driving defensively when confronting a zombie epidemic

scientific article published on 5 November 2013

Concurrent anxiety and substance use disorders among outpatients with major depression: clinical features and effect on treatment outcome

scientific article

Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults

scientific article (publication date: 2009)

Deficits in psychological well-being and quality-of-life in minor depression: implications for DSM-V.

scientific article published on 4 March 2010

Delirium and its prevention with melatonergic drugs

scientific article published on May 2014

Deprescribing to Reduce Medication Use: Will This Help Your Patient?

scientific article published on November 2016

Deuterated Drugs

article

Diagnostic Classification Past, Present, and Future: Implications for Pharmacotherapy ⬇️

scientific article published on February 28, 2013

Dietary Supplement Drug Therapies for Depression ⬇️

scientific article published on May 18, 2012

Difference in treatment outcome in outpatients with anxious versus nonanxious depression: a STAR*D report.

scientific article published on 2 January 2008

Do Psychiatric Medications Cause More Harm Than Good?

scientific article published in July 2015

Does comorbid substance use disorder impair recovery from major depression with SSRI treatment? An analysis of the STAR*D level one treatment outcomes

scientific article

Does the Duration of Index Episode Affect the Treatment Outcome of Major Depressive Disorder?

Does the duration of index episode affect the treatment outcome of major depressive disorder? A STAR*D report

scientific article published on August 2008

Double-blind switch study of imipramine or sertraline treatment of antidepressant-resistant chronic depression

scientific article published on March 2002

Down the hatch: is prescribing medication really that simple?

scientific article published on July 2014

Drug Therapies for Tardive Dyskinesia: Part 1

article

Drug Therapies for Tardive Dyskinesia: Part 2 ⬇️

scientific article published on June 15, 2011

Drug therapies for cognitive impairment and dementia

scientific article published in April 2010

Early- versus late-onset dysthymic disorder: comparison in out-patients with superimposed major depressive episodes

article

Early-life milk and late-life fracture

scientific article

Economic anxiety

scientific article published in March 2009

Editorial: Deep brain stimulation and aggression

scientific article published on 07 June 2013

Effect of concurrent substance use disorder on the effectiveness of single and combination antidepressant medications for the treatment of major depression: an exploratory analysis of a single-blind randomized trial

scientific article published in February 2012

Effective Medication Management ⬇️

scientific article published on February 15, 2012

Effectiveness of a quantitative electroencephalographic biomarker for predicting differential response or remission with escitalopram and bupropion in major depressive disorder

scientific article published on 26 August 2009

Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study

scientific article published on September 2005

Effects of aging on pharmacokinetic and pharmacodynamic drug processes

scientific article published in October 2009

Effects of sertraline on sleep architecture in patients with depression

scientific article published in December 2003

Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression

scientific article published on 22 May 2015

Electroencephalography technology for predicting response to antidepressant medications.

scientific article published on October 2006

Epidural cortical stimulation of the left dorsolateral prefrontal cortex for refractory major depressive disorder

scientific article published in November 2011

Escitalopram and QTc prolongation

scientific article published in July 2013

Evaluating the Bioavailability and Bioequivalence of Generic Medications

scientific article published on 01 January 2010

Evaluating the safety of medications during pregnancy and lactation

scientific article published on March 2009

Factors associated with chronic depressive episodes: a preliminary report from the STAR-D project

scientific article published on 01 December 2005

Factors predicting reduced antidepressant response: experience with the SNRI duloxetine in patients with major depression

scientific article published in October 2008

Feasibility Study of the Safety and Effectiveness of an Implantable Cortical Stimulation System for Subjects with Major Depression

article published in 2007

Fluoxetine treatment of depression in mentally retarded adults

scientific article

Future Prospects for Pharmacogenetics in the Quest for Personalized Medicine ⬇️

scientific article published on December 1, 2012

Gabapentin for Substance Use Disorders: Is it Safe and Appropriate?

scientific article

Gabapentin for the treatment of substance use disorders

scientific article published on December 2013

Gabapentin: can it be misused?

scientific article published in January 2014

General health, health care utilization, and medical comorbidity in dysthymia

scientific article

Glutamate-modulating drugs & the treatment of mental disorders.

scientific article published on January 2007

Group comparisons of DSM-IV subtypes of chronic depression: validity of the distinctions, part 2.

scientific article

Herbal therapies.

scientific article published in April 2005

Hey Mister Tambourine Man, Play a Drug for Me: Music as Medication

scientific article

How are drugs approved? Part 1: the evolution of the Food and Drug Administration

scientific article published on January 2008

How are drugs approved? Part 2: ethical foundations of clinical research

scientific article published on February 2008

How are drugs approved? Part 3. The stages of drug development.

scientific article published on March 2008

In Reply

Induction of Mania With Serotonin Reuptake Inhibitors

article

Is cognitive behavior therapy just a ‘nonspecific’ intervention for depression? A retrospective comparison of consecutive cohorts treated with cognitive behavior therapy or supportive counseling and pill placebo

article

Ketamine for the treatment of depression

scientific article published in January 2013

Limitations of evidence in the practice of evidence-based medicine.

scientific article

Lithium augmentation of fluoxetine in the treatment of OCD and major depression: a case report

scientific article published in March 1991

Lithium-induced renal dysfunction

scientific article published on December 1994

Lithium: underappreciated and underused?

scientific article published on August 2007

Managing common Side effects of SSRIs.

scientific article published on February 2007

Markedly increased platelet membrane fluidity in Down syndrome with a (14q, 21q) translocation

scientific article published in October 1988

Maximizing the adequacy of medication treatment in controlled trials and clinical practice: STAR(*)D measurement-based care.

scientific article published on 4 April 2007

Medication adherence.

scientific article published in September 2007

Medication holidays

scientific article published in September 2009

Melatonin, Liraglutide, and Naltrexone/Bupropion for the Treatment of Obesity and Medication-Related Weight Gain

scientific article published on June 2015

Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem

scientific article published on August 2013

Methylene Blue: The Long and Winding Road From Stain to Brain: Part 2.

scientific article published in October 2016

Methylene Blue: The Long and Winding Road from Stain to Brain: Part 1.

scientific article published in September 2016

Mifepristone as a therapeutic agent in psychiatry

scientific article published on June 2013

More on antidepressant drugs and infectious disease

scientific article published on October 2013

Mortality risk of mirtazapine: guilt by association?

scientific article published in May 2014

Neurosurgical approaches to therapeutic brain stimulation for treatment-resistant depression

scientific article published in April 2008

New developments with vagus nerve stimulation therapy

scientific article published on March 2014

Novel melatonin-based treatments for major depression

scientific article published on 01 January 2012

Now Take a Deep Breath: Inhaled Loxapine for the Treatment of Acute Agitation ⬇️

scientific article published on December 29, 2011

Odds and ends in psychopharmacology from the past 10 years

scientific article published in January 2015

Off-Label Medication Use ⬇️

scientific article published on August 17, 2012

Oxazepam for the Treatment of Substance Abuse and Depression: Is it Appropriate?

scientific article published in May 2016

Peduncular hallucinosis

scientific article published on July 1, 2011

Personalized drug therapy with pharmacogenetics--part 2: pharmacodynamics.

scientific article

Personalized drug therapy with pharmacogenetics. Part 1: Pharmacokinetics.

scientific article

Pharmacogenetic testing in psychiatry: not (quite) ready for primetime

scientific article

Pharmacogenetics and Pharmacovigilance

scientific article published on 01 January 2009

Pharmacotherapy for insomnia

article

Pharmacotherapy for psychotropic drug-related weight gain.

scientific article published on July 2008

Pharmacotherapy in personality disorders.

scientific article published on June 2007

Pharmacotherapy of Inpatients with Bipolar Depression

Pharmacotherapy of dysthymia: a review.

scientific article published on April 1991

Pharmacotherapy of inpatients with bipolar depression

article

Pharmacotherapy strategies for treatment-resistant depression.

scientific article published on November 2006

Pimavanserin: An Inverse Agonist Antipsychotic Drug

scientific article published in June 2016

Potential Adverse Effects of Discontinuing Psychotropic Drugs ⬇️

scientific article published on August 23, 2010

Potential adverse effects of discontinuing psychotropic drugs. Part 1: Adrenergic, cholinergic, and histamine drugs

scientific article published on June 2010

Potential adverse effects of discontinuing psychotropic drugs. Part 3: Antipsychotic, dopaminergic, and mood-stabilizing drugs

scientific article published on August 2010

Potential adverse effects of discontinuing psychotropic drugs: part 2: antidepressant drugs

scientific article published on 22 June 2010

Predictors of attrition during initial (citalopram) treatment for depression: a STAR*D report

scientific article

Predictors of response to acute treatment of chronic and double depression with sertraline or imipramine

scientific article published in December 1998

Prescribing psychotropic medications during pregnancy and lactation: principles and guidelines

scientific article published on May 2009

Prescribing psychotropic medications for elderly patients

scientific article published in November 2009

Principles & practice of polypharmacotherapy

scientific article published in March 2006

Psychiatric medications and sudden cardiac death: putting the risk in perspective

scientific article published on February 2015

Psychopathology and mental retardation

scientific article published in December 1995

Psychosocial outcomes following long-term, double-blind treatment of chronic depression with sertraline vs placebo

scientific article published in August 2002

Psychotropic medication use: what will it do to my liver?

scientific article

Publication Bias and Outcome Reporting Bias: Agomelatine as a Case Example ⬇️

scientific article published on August 17, 2011

QTc Prolongation and Haloperidol: Just How Risky is This Drug?

scientific article published on 17 July 2014

Quantitative electroencephalogram biomarkers for predicting likelihood and speed of achieving sustained remission in major depression: a report from the biomarkers for rapid identification of treatment effectiveness in major depression (BRITE-MD) tr

scientific article published on January 2013

Questions to Ask When Selecting Medication ⬇️

scientific article published on June 15, 2012

Quetiapine and the need for a thorough QT/QTc study

scientific article

Quetiapine, QTc interval prolongation, and torsade de pointes: a review of case reports

scientific article

Ramelteon and the Prevention of Delirium

scientific article published on 01 October 2014

Randomized, placebo-controlled trial of nefazodone maintenance treatment in preventing recurrence in chronic depression.

scientific article published on October 2003

Refractory Depression: Relevance of Psychosocial Factors and Therapies

Risks and benefits of antipsychotic drugs in elderly patients with dementia

scientific article published in November 2008

Safety and Abuse Liability of Oxazepam: Is This Benzodiazepine Drug Underutilized?

scientific article published in April 2016

Selective serotonin reuptake inhibitors and mania

scientific article published on 01 December 1994

Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 1: study design

scientific article published on September 2008

Sequenced Treatment Alternatives to Relieve Depression (STAR*D). Part 2: Study outcomes

scientific article published on October 2008

Serendipity and Psychopharmacology ⬇️

scientific article published on September 22, 2010

Sertraline versus imipramine to prevent relapse in chronic depression.

scientific article

Sleep Interventions for the Treatment of Depression ⬇️

scientific article published on December 22, 2010

Sleep-Onset Rapid Eye Movement Periods in Neuropsychiatric Disorders: Implications for the Pathophysiology of Psychosis ⬇️

scientific article published on December 1, 1997

Somatic therapies for seasonal affective disorder

scientific article

Suvorexant: a novel therapy for the treatment of insomnia

scientific article published on October 2014

Switching strategies for the treatment of unipolar major depression

scientific article

The Reply

article

The Use of Dopaminergic and Stimulant Drugs for the Treatment of Depression ⬇️

scientific article published on January 20, 2012

The antidepressant effects of anticholinergic drugs

scientific article published on June 2009

The challenges of clinical psychopharmacological management

scientific article published on 25 April 2012

The comparative cardiac effects of haloperidol and quetiapine: parsing a review

scientific article published on June 2014

The diverse clinical uses of opioid receptor drugs

scientific article published in May 2010

The economic burden of treatment-resistant depression

scientific article published on 13 March 2013

The emerging use of technology for the treatment of depression and other neuropsychiatric disorders

scientific article published on February 1, 2011

The rarity of mania in Down's syndrome

scientific article published in March 1994

The role of ketamine in treatment-resistant depression: a systematic review

scientific article

The treatment of minor depression with St. John's Wort or citalopram: failure to show benefit over placebo

scientific article

The treatment of persons with dual diagnoses in a rural community

scientific article

Therapeutic Armamentarium for Treating Depression ⬇️

scientific article published on July 1, 2010

Therapeutic brain stimulation for mental disorders

scientific article published in February 2005

Therapies for Obesity and Medication-Associated Weight Gain ⬇️

scientific article published on April 18, 2013

Thyroid dysfunction in refractory depression: implications for pathophysiology and treatment.

scientific article

Thyroid function in mood disorders

scientific article published on 01 January 1995

Treating antidepressant nonresponders with augmentation strategies: an overview

scientific article

Trifluoperazine: A Sprightly Old Drug

scientific article

Understanding and Assessing Adverse Drug Reactions

scientific article published on 28 September 2011

Understanding chirality and stereochemistry: three-dimensional psychopharmacology

scientific article published on July 2009

Understanding the clinical profile of a drug on the basis of its pharmacology: mirtazapine as an example

scientific article published on December 2008

Understanding the placebo effect. Part 1: placebo use in clinical trials

scientific article published on May 2008

Understanding the placebo effect. Part 2: underlying psychological & neurobiological processes

scientific article published on June 2008

Unusual & serious adverse effects of SSRIs: recognition & management

article

Update on Newer Antipsychotic Drugs

scientific article published on 30 March 2011

Update on St. John’s Wort ⬇️

scientific article published on October 22, 2010

Update on deep brain stimulation

scientific article published on April 2014

Use of Computer and Mobile Technologies in the Treatment of Depression

scientific article

Use of endocrine hormones for treating depression

scientific article published on 22 November 2010

Vagus Nerve Stimulation

scientific article

Vagus nerve stimulation for treatment-resistant depression: a randomized, controlled acute phase trial.

scientific article

Vilazodone: another novel atypical antidepressant drug

scientific article published on 16 February 2011

Vitamin D and Depression

scientific article published on 21 January 2011

Weight gain with atypical antipsychotic drugs in bipolar disorder

scientific article published in September 2009

What You See Depends on Where You’re Looking and How You Look at It: Publication Bias and Outcome Reporting Bias ⬇️

scientific article published on July 15, 2011

What makes a generic medication generic?

scientific article published in December 2009

When Is a “Generic” Medication not Really a Generic?

scientific article published on 27 January 2010

When is a "generic" medication not really a generic?

scientific article published in February 2010

Where Are We Today with Personalized Medicine? ⬇️

scientific article published on October 15, 2012

Workplace performance effects from chronic depression and its treatment

article

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