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List of works by Claudia Maria Hattinger

4-Demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548): a promising new candidate for chemotherapeutic treatment of osteosarcoma patients.

scientific article published on September 2005

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

scientific article

Advances in emerging drugs for osteosarcoma

scientific article published on 28 May 2015

Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells

scientific article published on January 2004

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Array comparative genomic hybridization reveals frequent alterations of G1/S checkpoint genes in undifferentiated pleomorphic sarcoma of bone

scientific article published on 19 January 2011

CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progression

scientific article published on 25 October 2016

Candidate germline polymorphisms of genes belonging to the pathways of four drugs used in osteosarcoma standard chemotherapy associated with risk, survival and toxicity in non-metastatic high-grade osteosarcoma

scientific article published on 22 August 2016

Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma.

scientific article

Doxorubicin-resistant osteosarcoma: novel therapeutic approaches in sight?

scientific article published on 10 February 2017

Effect of TP53 Arg72Pro and MDM2 SNP309 polymorphisms on the risk of high-grade osteosarcoma development and survival

scientific article published in May 2009

Emerging drugs for high-grade osteosarcoma

scientific article published on 09 August 2010

Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma

scientific article published on 14 November 2018

Excision repair cross-complementation group 1 protein expression predicts survival in patients with high-grade, non-metastatic osteosarcoma treated with neoadjuvant chemotherapy

scientific article

Fine-mapping of cytogenetically undetectable EWS/ERG fusions on DNA fibers of Ewing tumors

scientific article published in January 2001

Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study.

scientific article

Genetic analysis of fibrosarcoma of bone, a rare tumour entity closely related to osteosarcoma and malignant fibrous histiocytoma of bone

article

Genetic testing for high-grade osteosarcoma: a guide for future tailored treatments?

scientific article published on 19 October 2018

Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients

scientific article published on 6 December 2017

Genome-wide association study identifies two susceptibility loci for osteosarcoma

scientific article (publication date: July 2013)

Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques.

scientific article published in September 2003

Genomic imbalances associated with secondary acute leukemias in Hodgkin lymphoma

scientific article published on 01 December 2007

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance

scientific article published on 27 April 2016

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Induction of p21 mRNA synthesis after short-wavelength UV light visualized in individual cells by RNA FISH.

scientific article

Malignant fibrous histiocytoma of bone: Analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry

scientific article published on 19 April 2006

Mechanisms of gene amplification and evidence of coamplification in drug-resistant human osteosarcoma cell lines.

scientific article

Metastatic extraosseous Ewing tumor: Association of the additional translocation der(16)t(1;16) with the variant EWS/ERG rearrangement in a case of cytogenetically inconspicuous chromosome 22

scientific article published on 01 April 1996

Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma

scientific article published on 27 July 2016

Molecular Cytogenetics in Ewing Tumors: Diagnostic and Prognostic Information

scientific article published in October 2000

Molecular alterations of monophasic synovial sarcoma: loss of chromosome 3p does not alter RASSF1 and MLH1 transcriptional activity

scientific article published on 01 February 2006

Neuroblastoma cells can actively eliminate supernumerary MYCN gene copies by micronucleus formation--sign of tumour cell revertance?

scientific article published on October 1997

Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy.

scientific article

Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma

scientific article published in August 2008

P53 oncosuppressor influences selection of genomic imbalances in response to ionizing radiations in human osteosarcoma cell line SAOS-2.

scientific article

Peripheral primitive neuroectodermal tumour of the cervix

scientific article published on 01 January 2000

Pharmacogenomics of genes involved in antifolate drug response and toxicity in osteosarcoma

scientific article published on 19 October 2016

Pharmacogenomics of second-line drugs used for treatment of unresponsive or relapsed osteosarcoma patients.

scientific article published on 24 November 2016

Polymorphisms of genes related to metotrexate response and toxicity in high-grade osteosarcoma

article

Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma

scientific article published on 15 October 2013

Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing's sarcoma

scientific article

Prognostic impact of deletions at 1p36 and numerical aberrations in Ewing tumors

scientific article published in March 1999

Quality assessment of genetic markers used for therapy stratification.

scientific article published in June 2003

Role of pharmacogenetics of drug-metabolizing enzymes in treating osteosarcoma

scientific article published on 22 June 2015

Sensitive mRNA detection by fluorescence in situ hybridization using horseradish peroxidase-labeled oligodeoxynucleotides and tyramide signal amplification.

scientific article

Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma

scientific article

Targeting CDKs with Roscovitine Increases Sensitivity to DNA Damaging Drugs of Human Osteosarcoma Cells

scientific article

Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy.

scientific article published in January 2011

Targeting polo-like kinase 1 by NMS-P937 in osteosarcoma cell lines inhibits tumor cell growth and partially overcomes drug resistance

scientific article published on 7 September 2014

The EWS protein is dispensable for Ewing tumor growth.

scientific article published in August 2001

The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71.

scientific article published on December 2005

The pharmacogenomics of osteosarcoma

scientific article published on 31 May 2016

Unequivocal identification of disseminated tumor cells in the bone marrow by combining immunological and genetic approaches--functional and prognostic information

scientific article published in February 2001

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