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List of works by Ana I. Duarte

Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.

scientific article published on 20 May 2014

Alzheimer disease as a vascular disorder: where do mitochondria fit?

scientific article published on 21 July 2012

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

scientific article published on January 2009

Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats

scientific article published on 2 June 2017

Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease.

scientific article published on 19 February 2018

Carvedilol improves energy production during acute global myocardial ischaemia

scientific article

Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration.

scientific article published on 11 January 2013

Current and emerging avenues for Alzheimer's disease drug targets

scientific article published on 29 August 2019

Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's Disease.

scientific article published on 12 June 2018

Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase.

scientific article

Food deprivation promotes oxidative imbalance in rat brain

scientific article published in January 2009

Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington's disease

scientific article published on 24 October 2017

Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease.

scientific article published on 25 January 2017

Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins.

scientific article published on May 2013

IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice.

scientific article published on 18 December 2013

IGF-1 protects against diabetic features in an in vivo model of Huntington's disease.

scientific article

Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions

scientific article

Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin.

scientific article published on 03 February 2016

Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease - How Anti-Diabetics Could be a Solution for Dementia

scientific article

Insulin in Central Nervous System: More than Just a Peripheral Hormone

scientific article published on February 21, 2012

Insulin neuroprotection against oxidative stress in cortical neurons--involvement of uric acid and glutathione antioxidant defenses.

scientific article

Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression

scientific article

Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.

scientific article published in October 2006

Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats

scientific article

Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions

scientific article published on October 2015

Liraglutide Protects Against Brain Amyloid-β1-42 Accumulation in Female Mice with Early Alzheimer's Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation

scientific article published on 04 March 2020

Metabolic regulation is important for spermatogenesis.

scientific article

Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes.

scientific article published in July 2008

Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology.

scientific article published on 11 October 2016

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers.

scientific article published on 23 May 2013

Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H2O2.

scientific article published on 15 May 2013

Oxidative stress affects synaptosomal gamma-aminobutyric acid and glutamate transport in diabetic rats: the role of insulin

scientific article

Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection

scientific article published on 14 September 2014

Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress

scientific article published on 20 December 2013

Protective effect of trimetazidine on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia

scientific article published in October 2004

Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells

scientific article

The impairment of insulin signaling in Alzheimer's disease

scientific article published on November 6, 2012

The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease.

scientific article published on 14 May 2014

The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases

scientific article published on 19 June 2015

Valsartan improves mitochondrial function in hearts submitted to acute ischemia

scientific article published in August 2005