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List of works by Graeme L Conn

30S Subunit-dependent activation of the Sorangium cellulosum So ce56 aminoglycoside resistance-conferring 16S rRNA methyltransferase Kmr.

scientific article

A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis

scientific article published on 27 December 2016

A compact RNA tertiary structure contains a buried backbone-K+ complex

scientific article

A human cellular noncoding RNA activates the antiviral protein 2'-5'-oligoadenylate synthetase 1

scientific article published in Journal of Biological Chemistry

A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1

scientific article

Adenovirus VA RNA: An essential pro-viral non-coding RNA.

scientific article published on 25 June 2015

Aminoglycoside resistance genes sgm and kgmB protect bacterial but not yeast small ribosomal subunits in vitro despite high conservation of the rRNA A-site.

scientific article

Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications

scientific article published on 3 February 2008

Cis-acting ribozymes for the production of RNA in vitro transcripts with defined 5' and 3' ends

scientific article published on 01 January 2012

Coevolution of protein and RNA structures within a highly conserved ribosomal domain

scientific article published on 01 February 2005

Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G.

scientific article published on December 2003

Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm.

scientific article

Distinct contributions of T1R2 and T1R3 taste receptor subunits to the detection of sweet stimuli

scientific article published on 01 November 2005

Dysregulation of M segment gene expression contributes to influenza A virus host restriction

scientific article published on 15 August 2019

Expression and purification of functional ligand-binding domains of T1R3 taste receptors

scientific article published on 18 April 2006

Expression of active RNA-activated protein kinase (PKR) in bacteria ⬇️

scientific article published on October 1, 2003

Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies.

scientific article

Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization

scientific article

Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition

scientific article published on 08 October 2019

General plasmids for producing RNA in vitro transcripts with homogeneous ends

scientific article

General protocols for preparation of plasmid DNA template, RNA in vitro transcription, and RNA purification by denaturing PAGE

scientific article published on 01 January 2012

Heterologous Escherichia coli expression, purification and characterization of the GrmA aminoglycoside-resistance methyltransferase

scientific article

Heterologous Expression and Functional Characterization of the Exogenously Acquired Aminoglycoside Resistance Methyltransferases RmtD, RmtD2, and RmtG.

scientific article

Heterozygous <i>OAS1</i> gain-of-function variants cause an autoinflammatory immunodeficiency

scientific article published on 01 June 2021

Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR.

scientific article published on 9 January 2017

Identification of new inhibitors of protein kinase R guided by statistical modeling ⬇️

scientific article published on May 13, 2011

Magnesium-dependent interaction of PKR with adenovirus VAI.

scientific article published on 14 August 2010

Optimization of a ribosomal structural domain by natural selection

scientific article published on May 2006

Plasmid template design and in vitro transcription of short RNAs within a "structure cassette" for structure probing experiments

scientific article published on 01 January 2012

Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES.

scientific article published on 30 January 2007

Recombinant RNA expression.

scientific article published in July 2007

Reduced Sweetness of a Monellin (MNEI) Mutant Results from Increased Protein Flexibility and Disruption of a Distant Poly-(L-Proline) II Helix

scientific article

Substrate Recognition and Modification by a Pathogen-Associated Aminoglycoside Resistance 16S rRNA Methyltransferase

scientific article

Substrate recognition by the Pseudomonas aeruginosa EF-Tu-modifying methyltransferase EftM

scientific article published on 21 November 2019

Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase.

scientific article published on 22 April 2008

The PKR-binding domain of adenovirus VA RNAI exists as a mixture of two functionally non-equivalent structures

scientific article published on 27 July 2009

The Pathogen-Derived Aminoglycoside Resistance 16S rRNA Methyltransferase NpmA Possesses Dual m1A1408/m1G1408 Specificity.

scientific article

The Regulatory and Kinase Domains but Not the Interdomain Linker Determine Human Double-stranded RNA-activated Kinase (PKR) Sensitivity to Inhibition by Viral Non-coding RNAs

scientific article

The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications

scientific article (publication date: 15 May 2003)

Trimethylation of Elongation Factor-Tu by the Dual Thermoregulated Methyltransferase EftM Does Not Impact Its Canonical Function in Translation

scientific article published on 05 March 2019

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