Search filters

List of works by Xu Dong Zhang

2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2

scientific article

A Six-Epithelial-Mesenchymal Transition Gene Signature May Predict Metastasis of Triple-Negative Breast Cancer

scientific article published on 03 July 2020

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

scientific article (publication date: 9 August 2016)

A p53-responsive microRNA network promotes cancer cell quiescence

scientific article published on 09 October 2018

ACTN4 regulates the stability of RIPK1 in melanoma.

scientific article

AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma

scientific article (publication date: 7 November 2013)

Activation of Jun N-terminal kinase is a mediator of vincristine-induced apoptosis of melanoma cells

scientific article published on February 2008

Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma.

scientific article published on November 2005

Adipocytes contribute to resistance of human melanoma cells to chemotherapy and targeted therapy.

scientific article published on April 2014

Antiproliferative effects of continued mitogen-activated protein kinase pathway inhibition following acquired resistance to BRAF and/or MEK inhibition in melanoma.

scientific article

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

scientific article

Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS

scientific article

Applications of nanotechnology for melanoma treatment, diagnosis, and theranostics

scientific article published on 24 July 2013

Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination

scientific article

Autophagy induced by DAMPs facilitates the inflammation response in lungs undergoing ischemia-reperfusion injury through promoting TRAF6 ubiquitination.

scientific article published on 03 February 2017

BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.

scientific article

Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells

scientific article published on 01 December 2006

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress

scientific article published on 30 May 2019

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells

scientific article

Contrasting effects of nutlin-3 on TRAIL- and docetaxel-induced apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells

scientific article published on December 2010

Cooperativity of HOXA5 and STAT3 is critical for HDAC8 inhibition-mediated transcriptional activation of PD-L1 in human melanoma cells.

scientific article published on 22 November 2017

Correction to: RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors

scientific article published on 05 March 2019

Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3.

scientific article published on 06 June 2013

Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model.

scientific article published on January 2006

Differential localization and regulation of death and decoy receptors for TNF-related apoptosis-inducing ligand (TRAIL) in human melanoma cells

scientific article (publication date: 15 April 2000)

Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice

scientific article published on September 2015

Docetaxel-induced apoptosis in melanoma cells is dependent on activation of caspase-2.

scientific article published on February 2007

Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway

scientific article published on February 2007

Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence

article published in the Proceedings of the National Academy of Sciences of the United States of America

Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products

scientific article

ER stress-induced autophagy in melanoma

scientific article published on August 2015

Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression

scientific article published on 06 June 2014

Effects of cisplatin combined with heparanase inhibitor on proliferation and invasion of human nasopharyngeal carcinoma cells

scientific article published in April 2013

Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress.

scientific article

Evidence for upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors.

scientific article

Expression of catenins and p120cas in melanocytic nevi and cutaneous melanoma: deficient alpha-catenin expression is associated with melanoma progression

scientific article published on 01 August 1999

Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma.

scientific article published in March 2009

Functional identification of a novel transcript variant of INPP4B in human colon and breast cancer cells.

scientific article published on 8 February 2017

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability.

scientific article

Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells.

scientific article published on 8 October 2008

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors.

scientific article published on January 2012

How melanoma cells evade trail-induced apoptosis.

scientific article

Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin

scientific article published on February 2006

Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax.

scientific article published on September 2009

INPP4B is an oncogenic regulator in human colon cancer.

scientific article published on 28 September 2015

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas.

scientific article published on 9 November 2015

Implication of Unfolded Protein Response and Autophagy in the Treatment of BRAF Inhibitor Resistant Melanoma

scientific article published on 29 September 2015

Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells.

scientific article

Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis

scientific article

Inhibition of autophagy by 3-MA enhances endoplasmic reticulum stress-induced apoptosis in human nasopharyngeal carcinoma cells.

scientific article published on 29 July 2013

Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein

scientific article

Insulin induces drug resistance in melanoma through activation of the PI3K/Akt pathway

scientific article published on 17 February 2014

Involvement of BH3-only proapoptotic proteins in mitochondrial-dependent Phenoxodiol-induced apoptosis of human melanoma cells

scientific article published on 01 November 2006

Involvement of endoplasmic reticulum stress in Docetaxel-induced JNK-dependent apoptosis of human melanoma

scientific article

Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.

scientific article

Is Apaf-1 expression frequently abrogated in melanoma?

article

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

scientific article published on 25 July 2019

Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins

scientific article published on 16 October 2009

LncRNA GIRGL drives CAPRIN1-mediated phase separation to suppress glutaminase-1 translation under glutamine deprivation

scientific article published in 2021

LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect.

scientific article

LncRNA REG1CP promotes tumorigenesis through an enhancer complex to recruit FANCJ helicase for REG3A transcription

scientific article published on 25 November 2019

Low expression of microRNA-146b-5p and microRNA-320d predicts poor outcome of large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone

scientific article published on 18 April 2014

Lymphoid cell infiltration during breast cancer growth: a syngeneic rat model

scientific article published on 01 December 1998

MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.

scientific article published on 18 November 2010

Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma

scientific article

Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma

scientific article published on 01 April 2007

Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types

scientific article (publication date: 6 October 2000)

Melanoma cell sensitivity to Docetaxel-induced apoptosis is determined by class III beta-tubulin levels

scientific article published on 18 December 2007

Metabolic approaches to treatment of melanoma.

scientific article published on 27 October 2009

MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer

scientific article

MicroRNA-645 is an oncogenic regulator in colon cancer.

scientific article published on 15 May 2017

Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.

scientific article

Neurotrophin Receptors TrkA, p75NTR, and Sortilin Are Increased and Targetable in Thyroid Cancer

scientific article published on 13 October 2017

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

scientific article

Nucleotide excision repair gene expression after Cisplatin treatment in melanoma

scientific article published on 31 August 2010

OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis

scientific article

Obesity and melanoma: exploring molecular links

scientific article published on September 2013

Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress.

scientific article published on 6 August 2013

Oncogenic suppression of PHLPP1 in human melanoma

scientific article published on 14 October 2013

Osteogenic responses to extraskeletally implanted synthetic porous calcium phosphate ceramics: an early stage histomorphological study in dogs

scientific article published on 01 November 1997

P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation

scientific article

PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma

scientific article published on January 2013

Palmitoylation of CD36/FAT regulates the rate of its post-transcriptional processing in the endoplasmic reticulum

scientific article published on 13 July 2010

Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor–related apoptosis-inducing ligand

article

RIP1 Kinase Is an Oncogenic Driver in Melanoma.

scientific article

RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors.

scientific article

RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.

scientific article

Regulation of PD-L1: a novel role of pro-survival signalling in cancer.

scientific article published on 17 December 2015

Regulation of docetaxel-induced apoptosis of human melanoma cells by different isoforms of protein kinase C.

scientific article published on October 2007

Regulators of global genome repair do not respond to DNA damaging therapy but correlate with survival in melanoma

scientific article

Relative resistance of fresh isolates of melanoma to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis.

scientific article

Resistance of follicular lymphoma cells to chemotherapy is more than just BCL-2.

scientific article published in September 2003

Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota

scientific article published on 06 November 2019

Selection for TRAIL resistance results in melanoma cells with high proliferative potential

scientific article

Serum protein profiles of patients with lung cancer of different histological types

scientific article published on 15 December 2015

Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.

scientific article

Small molecular weight variants of p53 are expressed in human melanoma cells and are induced by the DNA-damaging agent cisplatin.

scientific article

Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion

scientific article

Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways

Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress ⬇️

scientific article published on June 28, 2012

Suppression of SHIP2 contributes to tumorigenesis and proliferation of gastric cancer cells via activation of Akt.

scientific article

Suppression of endoplasmic reticulum stress-induced invasion and migration of breast cancer cells through the downregulation of heparanase

scientific article published on 5 March 2013

Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress

scientific article published on 12 November 2013

TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria

scientific article published on 01 November 2000

TRAIL-induced apoptosis of human melanoma cells involves activation of caspase-4.

scientific article

TRIM16 inhibits proliferation and migration through regulation of interferon beta 1 in melanoma cells

scientific article

Targeted therapy of <i>TERT</i>-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy

scientific article published on 11 December 2020

Temozolomide induces senescence but not apoptosis in human melanoma cells.

scientific article published on 30 October 2007

Thapsigargin sensitizes human melanoma cells to TRAIL-induced apoptosis by up-regulation of TRAIL-R2 through the unfolded protein response.

scientific article published on 25 July 2007

The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance

scientific article published on 20 October 2012

The Emerging Role of the Microenvironment in Endometrial Cancer

scientific article published on 30 October 2018

The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription.

scientific article published on 16 February 2017

The application of fungal β-glucans for the treatment of colon cancer.

scientific article published on June 2013

The double life of RIPK1.

scientific article published on 26 May 2015

The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers.

scientific article published on October 2011

The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.

scientific article published on April 2004

The histone deacetylase inhibitor suberic bishydroxamate: a potential sensitizer of melanoma to TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis.

scientific article published on October 2003

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

scientific article published on 05 November 2019

The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells.

scientific article

The utility of the proliferative index in pretreatment biopsy specimens of esophageal squamous cell carcinoma

scientific article published on 01 October 1998

Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response

scientific article

Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress.

scientific article published in August 2008

Variable expression of protein kinase C epsilon in human melanoma cells regulates sensitivity to TRAIL-induced apoptosis

scientific article

c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis

scientific article published on 05 October 2020

Paulina is supported by:

About Paulina

Help