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List of works by Carlos F. Lagos

11β-hydroxysteroid dehydrogenase type 2 polymorphisms and activity in a Chilean essential hypertensive and normotensive cohort.

scientific article published on 26 January 2012

A new presentation of the chimeric CYP11B1/CYP11B2 gene with low prevalence of primary aldosteronism and atypical gene segregation pattern

scientific article published on 14 November 2011

A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development

scientific journal article

APOA5 Q97X mutation identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family

scientific article

Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation

scientific article published on 26 February 2020

Aldosterone Production and Signaling Dysregulation in Obesity.

scientific article published on March 2016

An amphipathic alpha-helix in the prodomain of cocaine and amphetamine regulated transcript peptide precursor serves as its sorting signal to the regulated secretory pathway.

scientific article

An eleven amino acid residue deletion expands the substrate specificity of acetyl xylan esterase II (AXE II) from Penicillium purpurogenum.

scientific article published in December 2007

Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1.

scientific article

Calpain inhibitors prevent p38 MAPK activation and germ cell apoptosis after heat stress in pubertal rat testes

scientific article published on 01 November 2009

Citosine-Adenine-Repeat Microsatellite of 11β-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children.

scientific article

Computational modeling study of functional microdomains in cannabinoid receptor type 1.

scientific article published on 26 February 2008

Cortisol/cortisone ratio and matrix metalloproteinase-9 activity are associated with pediatric primary hypertension.

scientific article published in September 2016

Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function

scientific article

Design, synthesis, binding and docking-based 3D-QSAR studies of 2-pyridylbenzimidazoles--a new family of high affinity CB1 cannabinoid ligands.

scientific article

Design, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1

scientific article published on 13 January 2015

Dictyostelium discoideum as a surrogate host-microbe model for antivirulence screening in Pseudomonas aeruginosa PAO1.

scientific article published on 18 March 2016

Divergent metabolic phenotype between two sisters with congenital generalized lipodystrophy due to double AGPAT2 homozygous mutations. a clinical, genetic and in silico study.

scientific article published on 31 January 2014

Docking and quantitative structure-activity relationship studies for the bisphenylbenzimidazole family of non-nucleoside inhibitors of HIV-1 reverse transcriptase

scientific article

Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening.

scientific article published on 18 January 2014

LC-MS/MS Method for the Simultaneous Determination of Free Urinary Steroids

scientific article published on 11 February 2014

Molecular Dynamics Simulations of Cx26-Wt and Deafness Related Mutants M34A, A40G and V37I

article

Molecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione

scientific article published on 06 September 2011

Next-Generation Sequencing Reveals Novel Genetic Variants (SRY, DMRT1, NR5A1, DHH, DHX37) in Adults With 46,XY DSD

scientific article published on 10 October 2019

Novel FXa Inhibitor Identification through Integration of Ligand- and Structure-Based Approaches.

scientific article

Novel splice-affecting variants in CYP27A1 gene in two Chilean patients with Cerebrotendinous Xanthomatosis

scientific article published on 17 March 2014

Polymorphisms in the RAC1 gene are associated with hypertension risk factors in a Chilean pediatric population.

scientific article published on 2 February 2014

Pregnancy normalized familial hyperaldosteronism type I: a novel role for progesterone?

scientific article published on 19 June 2014

Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system.

scientific article

Structural requirements of the human sodium-dependent bile acid transporter (hASBT): role of 3- and 7-OH moieties on binding and translocation of bile acids

scientific article

The Expression of RAC1 and Mineralocorticoid Pathway-Dependent Genes are Associated With Different Responses to Salt Intake

scientific article published on 27 November 2014

Usefulness and Pitfalls in Sodium Intake Estimation: Comparison of Dietary Assessment and Urinary Excretion in Chilean Children and Adults.

scientific article published on 8 June 2016

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