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List of works by Birgitte Rahbek Kornum

5-HT radioligands for human brain imaging with PET and SPECT

scientific article

A critical look at the function of the P2Y11 receptor

scientific article published on 31 May 2016

A novel spatial Delayed Non-Match to Sample (DNMS) task in the Göttingen minipig

scientific article published on 25 July 2008

Absence of autoreactive CD4+ T-cells targeting HLA-DQA1*01:02/DQB1*06:02 restricted hypocretin/orexin epitopes in narcolepsy type 1 when detected by EliSpot

scientific article published on 04 May 2017

Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain

scientific article

Altered surface expression of P2Y11 receptor with narcolepsy-associated mutations

scientific article published on 14 May 2019

An approach for serotonin depletion in pigs: effects on serotonin receptor binding

scientific article published on February 2011

An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus

scientific article

Author Correction: In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls ⬇️

scientific article published on 08 January 2020

CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy

scientific article published on December 2013

CD8 T cells from patients with narcolepsy and healthy controls recognize hypocretin neuron-specific antigens

scientific article published on 19 February 2019

Central serotonin depletion affects rat brain areas differently: a qualitative and quantitative comparison between different treatment schemes

scientific article

Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy

scientific article

Cerebrospinal Fluid Hypocretin-1 (Orexin-A) Level Fluctuates with Season and Correlates with Day Length

scientific article

Cerebrospinal fluid cytokine levels in type 1 narcolepsy patients very close to onset

scientific article

Cognitive testing of pigs (Sus scrofa) in translational biobehavioral research

scientific article published on 27 May 2010

Common variants in P2RY11 are associated with narcolepsy

scientific article

DNMT1 regulates expression of MHC class I in post-mitotic neurons.

scientific article published on 3 July 2018

DQB1*06:02 allele-specific expression varies by allelic dosage, not narcolepsy status

scientific article

Decoding the porcine developing spatial processing system and production of human entorhinal stellate cell-like cells by a direct programming approach

scientific article

Does autoreactivity have a role in narcolepsy?

scientific article published in November 2014

EIF3G is associated with narcolepsy across ethnicities

scientific article

Early IVIg treatment has no effect on post-H1N1 narcolepsy phenotype or hypocretin deficiency

scientific article published on 20 June 2012

Erratum: Common variants in P2RY11 are associated with narcolepsy

scholarly article published in Nature Genetics

Evaluation of the novel 5-HT4 receptor PET ligand [11C]SB207145 in the Göttingen minipig

scientific article

Flow cytometry analysis of T-cell subsets in cerebrospinal fluid of narcolepsy type 1 patients with long-lasting disease

scientific article published on 3 January 2018

GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

scientific article

Genetics of Human Sleep and Sleep Disorders

HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy.

scientific article published in May 2015

HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy

scientific article

High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y11 protein levels in narcolepsy type 1

scientific article published on 01 August 2021

Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death.

scientific article published on 8 June 2018

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

scientific article

In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

scientific article published on 20 November 2019

Increased interferon-mediated immunity following in vitro and in vivo Modafinil treatment on peripheral immune cells

scientific article

Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes

scientific article published on 11 February 2020

MiRNA profiles in cerebrospinal fluid from patients with central hypersomnias

scientific article published on 2 October 2014

Monozygotic twins discordant for narcolepsy type 1 and multiple sclerosis.

scientific article published on 16 June 2016

Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

scientific article published on 24 January 2020

Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy

scientific article

N-terminal tagging of human P2X7 receptor disturbs calcium influx and dye uptake.

scientific article published on 30 December 2017

Narcolepsy

Narcolepsy Type 1: What have we learned from immunology?

scientific article published on 28 March 2020

Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination.

scientific article

Narcolepsy risk loci are enriched in immune cells and suggest autoimmune modulation of the T cell receptor repertoire

Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain

scientific article published on 30 September 2011

Neurobasal media facilitates increased specificity of siRNA-mediated knockdown in primary cerebellar cultures

scientific article

Normal Morning Melanin-Concentrating Hormone Levels and No Association with Rapid Eye Movement or Non-Rapid Eye Movement Sleep Parameters in Narcolepsy Type 1 and Type 2.

scientific article published on 14 November 2016

Novel method for evaluation of eye movements in patients with narcolepsy.

scientific article published on 21 December 2016

Pre-treatment of blood samples reveal normal blood hypocretin/orexin signal in narcolepsy type 1

scientific article published on 22 March 2021

Precipitants of Narcolepsy: Vaccines and Infections

Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy

scientific article

Radiosynthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET.

scientific article

Rare missense mutations in P2RY11 in narcolepsy with cataplexy.

scientific article published on 27 April 2017

Retraction of the research article: "CD4⁺ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy".

scientific article published in July 2014

Serotonin depletion results in a decrease of the neuronal activation caused by rivastigmine in the rat hippocampus

scientific article published on 19 January 2006

Serum cytokine levels in Kleine-Levin syndrome

scientific article

Sleep Disorders

Sleep spindle density in narcolepsy.

scientific article published on 18 March 2017

Sleep-wake stability in narcolepsy patients with normal, low and unmeasurable hypocretin levels.

scientific article published on 14 March 2017

Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

scientific article

Synthesis and biological evaluation of 125I/123I-labelled analogues of citalopram and escitalopram as potential radioligands for imaging of the serotonin transporter

scholarly article by Jacob Madsen et al published 30 November 2010 in Journal of Labelled Compounds and Radiopharmaceuticals

The European Narcolepsy Network (EU-NN) database

scientific article published on 26 January 2016

The association between narcolepsy and H1N1 influenza

scientific article published in March 2013

The case for narcolepsy as an autoimmune disease

scientific article published on 27 January 2020

The effect of the inter-phase delay interval in the spontaneous object recognition test for pigs

scientific article

The wake-promoting drug Modafinil prevents motor impairment in sickness behavior induced by LPS in mice: Role for dopaminergic D1 receptor

scientific article published on 9 May 2017

Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

scientific article published on 07 September 2020

Type 1 narcolepsy is not present in 29 HPV-vaccinated individuals with subjective sleep complaints

scientific article published on 01 November 2018

Type 1 narcolepsy: a CD8(+) T cell-mediated disease?

scientific article published on 10 June 2015

Validation of antibodies for neuroanatomical localization of the P2Y11 receptor in macaque brain.

scientific article published on 8 August 2016

miRNA profiles in plasma from patients with sleep disorders reveal dysregulation of miRNAs in narcolepsy and other central hypersomnias

scientific article

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