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List of works by Gudmundur Johannsson

A 10-year, prospective study of the metabolic effects of growth hormone replacement in adults.

scientific article

A polymorphism in the CYP17A1 gene influences the therapeutic response to steroidogenesis inhibitors in Cushing's syndrome.

scientific article published on 30 June 2017

A prospective investigation of quality of life and psychological well-being after the discontinuation of GH treatment in adolescent patients who had GH deficiency during childhood.

scientific article published in August 2001

A reappraisal of the diagnosis of growth hormone deficiency

scientific article published on 01 April 2010

Achieving a physiological cortisol profile with once-daily dual-release hydrocortisone: a pharmacokinetic study

scientific article published on 29 April 2016

Acupuncture for ovulation induction in polycystic ovary syndrome: a randomized controlled trial

scientific article

Adiponectin, leptin, and erythrocyte sodium/lithium countertransport activity, but not resistin, are related to glucose metabolism in growth hormone-deficient adults.

scientific article published on 5 January 2005

Adrenal insufficiency: review of clinical outcomes with current glucocorticoid replacement therapy

scientific article published on 10 October 2014

Adrenal venous sampling: the learning curve of a single interventionalist with 282 consecutive procedures.

scientific article published on 21 February 2018

Aldosterone to Renin Ratio as a Screening Instrument for Primary Aldosteronism in a Middle-Aged Population with Atrial Fibrillation.

scientific article published on 21 September 2017

Baseline Characteristics and Effects of Growth Hormone Therapy over Two Years in Younger and Elderly Adults with Adult Onset GH Deficiency

scientific article published on 29 August 2006

Baseline characteristics and effects of ten years of growth hormone (GH) replacement therapy in adults previously treated with pituitary irradiation

scientific article published on 11 September 2013

Baseline characteristics and response to GH replacement of hypopituitary patients previously irradiated for pituitary adenoma or craniopharyngioma: data from the Pfizer International Metabolic Database.

scientific article

Baseline characteristics and the effects of two years of growth hormone (GH) replacement therapy in adults with GH deficiency previously treated for acromegaly

scientific article published on 8 April 2008

Baseline characteristics and the effects of two years of growth hormone replacement therapy in adults with growth hormone deficiency previously treated for Cushing's disease

scientific article

Bioelectrical impedance spectroscopy in growth hormone-deficient adults.

scientific article published on 26 November 2009

Biomarkers of GH action in children and adults

scientific article published on 20 March 2018

Body composition and bone mineral density in women with Cushing's syndrome in remission and the association with common genetic variants influencing glucocorticoid sensitivity

article

Body composition and quality of life as markers of the efficacy of growth hormone replacement therapy in adults.

scientific article

Body composition during GH replacement in adults – methodological variations with respect to gender

article

Bridging the gap: metabolic and endocrine care of patients during transition

scientific article

Cardiovascular and metabolic impact of glucocorticoid replacement therapy

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Cardiovascular risk factors in patients with Addison's disease: a comparative study of South African and Swedish patients.

scientific article

Central adiposity as an important confounder in the diagnosis of adult growth hormone deficiency.

scientific article

Clinical and Immunological Characteristics of Autoimmune Addison Disease: A Nationwide Swedish Multicenter Study

scientific article published on 21 November 2016

Clinical monitoring of growth hormone replacement in adults.

scientific article

Commencing growth hormone replacement in adults with a fixed low dose. Effects on serum lipoproteins, glucose metabolism, body composition, and cardiovascular function.

scientific article published in October 2001

Common genetic variants in the glucocorticoid receptor and the 11β-hydroxysteroid dehydrogenase type 1 genes influence long-term cognitive impairments in patients with Cushing's syndrome in remission

scientific article published on 10 June 2014

Comorbidities in patients with non-functioning pituitary adenoma: influence of long-term growth hormone replacement

scientific article published on 26 July 2018

Comorbidities, treatment patterns and cost-of-illness of acromegaly in Sweden: a register-linkage population-based study

scientific article

Comorbidity and cardiovascular risk factors in adult GH deficiency following treatment for Cushing's disease or non-functioning pituitary adenomas during childhood.

scientific article

Comparing progression of non-functioning pituitary adenomas in hypopituitarism patients with and without long-term GH replacement therapy

scientific article published on 04 September 2009

Comparison of the metabolic effects of raloxifene and oral estrogen in postmenopausal and growth hormone-deficient women.

scientific article published on 26 April 2005

Compromised quality of life in adult patients who have received a radiation dose towards the basal part of the brain. A case-control study in long-term survivors from cancer in the head and neck region

scientific article published on October 29, 2012

Current practice of glucocorticoid replacement therapy and patient-perceived health outcomes in adrenal insufficiency - a worldwide patient survey

scientific article published on June 13, 2012

Cushing's syndrome: a structured short- and long-term management plan for patients in remission

scientific article published on 04 October 2013

Decreased prefrontal functional brain response during memory testing in women with Cushing's syndrome in remission

scientific article published on 12 May 2017

Decreasing mortality and changes in treatment patterns in patients with acromegaly from a nationwide study.

scientific article published on 26 February 2018

Detection of genetic hypopituitarism in an adult population of idiopathic pituitary insufficiency patients with growth hormone deficiency.

scientific article published in September 2011

Diagnosing and Treating the Syndrome of Inappropriate Antidiuretic Hormone Secretion

scientific article published on 13 November 2015

Differential Effects of Raloxifene and Estrogen on Body Composition in Growth Hormone-Replaced Hypopituitary Women

article

Differential diagnosis of hyponatraemia.

scientific article published in March 2012

Discontinuation of growth hormone (GH) treatment: metabolic effects in GH-deficient and GH-sufficient adolescent patients compared with control subjects. Swedish Study Group for Growth Hormone Treatment in Children

scientific article published on 01 December 1999

Discontinuing long-term GH replacement therapy--a randomized, placebo-controlled crossover trial in adult GH deficiency.

scientific article published on 12 July 2012

Does long-term GH replacement therapy in hypopituitary adults with GH deficiency normalise quality of life?

scientific article published in July 2006

Early Clinical Indicators of Addison’s Disease in Adults with Type 1 Diabetes: a Nationwide, Observational, Cohort Study

scientific article published on 01 April 2019

Effect of growth-hormone therapy on early atherosclerotic changes in GH-deficient adults

scientific article published in The Lancet

Effect of short-term GH and testosterone administration on body composition and glucose homoeostasis in men receiving chronic glucocorticoid therapy

scientific article published on 17 January 2013

Effects of 3-year GH replacement therapy on bone mineral density in younger and elderly adults with adult-onset GH deficiency.

scientific article

Effects of GH and insulin-like growth factor-I on body composition.

scientific article published on September 2003

Effects of long-term growth hormone replacement in adults with growth hormone deficiency following cure of acromegaly: a KIMS analysis

scientific article

Efficacy and safety of bariatric surgery for craniopharyngioma-related hypothalamic obesity: a matched case–control study with 2 years of follow-up

scientific article published on 31 October 2016

End-stage renal disease: endocrine aspects of treatment.

scientific article

Estimation of body fluids with bioimpedance spectroscopy: state of the art methods and proposal of novel methods.

scientific article published on 14 September 2015

Ethnicity influences the diagnosis of primary adrenal insufficiency

scientific article published in May 2013

Excess Mortality in Women and Young Adults With Nonfunctioning Pituitary Adenoma: A Swedish Nationwide Study.

scientific article

Excess morbidity and mortality in patients with craniopharyngioma: a hospital-based retrospective cohort study

scientific article

Excess mortality and morbidity in patients with craniopharyngioma, especially in patients with childhood onset: a population-based study in Sweden.

scientific article published on 6 November 2014

Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency

scientific article

Exploring the use of recombinant human TSH in the diagnosis of central hypothyroidism.

scientific article published on 29 May 2008

Extended Support Within a Person-Centered Practice After Surgery for Patients With Pituitary Tumors: Protocol for a Quasiexperimental Study

scientific article published on 21 July 2020

Extracellular water and blood pressure in adults with growth hormone (GH) deficiency: a genotype-phenotype association study

scientific article

Fifteen years of GH replacement increases bone mineral density in hypopituitary patients with adult-onset GH deficiency.

scientific article

Five years of growth hormone replacement therapy in adults: age- and gender-related changes in isometric and isokinetic muscle strength.

scientific article

Fracture Incidence in GH-Deficient Patients on Complete Hormone Replacement Including GH

scientific article published on 01 December 2007

GDF15 Is Elevated in Conditions of Glucocorticoid Deficiency and Is Modulated by Glucocorticoid Replacement

scientific article published on 01 May 2020

GH Is Needed for the Maturation of Muscle Mass and Strength in Adolescents

scientific article published on 01 October 2001

GH and bone--experimental and clinical studies.

scientific article published in March 2000

GH effect on enzyme activity of 11betaHSD in abdominal obesity is dependent on treatment duration.

scientific article published in January 2006

GH replacement in adults: interactions with other pituitary hormone deficiencies and replacement therapies.

scientific article published on 14 August 2009

GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults

scientific article

GH secretory pattern in young adults who discontinued GH treatment for GH deficiency and decreased longitudinal growth in childhood

scientific article published on 01 July 2006

Genotypes associated with lipid metabolism contribute to differences in serum lipid profile of GH-deficient adults before and after GH replacement therapy

scientific article published on 19 June 2012

Growth Hormone (GH) Therapy in GH-Deficient Adults Influences the Response to a Dietary Load of Cholesterol and Saturated Fat in Terms of Cholesterol Synthesis, But Not Serum Low Density Lipoprotein Cholesterol Levels

scientific article published on 01 April 1999

Growth Hormone Reduces Inflammation in Postmenopausal Women with Abdominal Obesity: A 12-Month, Randomized, Placebo-Controlled Trial

scientific article published on 24 April 2007

Growth Hormone Research Society perspective on biomarkers of GH action in children and adults.

scientific article published on 26 February 2018

Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations

scientific article

Growth hormone (GH) replacement therapy in GH-deficient women during pregnancy

scientific article published on 01 August 2002

Growth hormone and ageing

scientific article published on 01 April 2000

Growth hormone and testosterone interact positively to enhance protein and energy metabolism in hypopituitary men.

scientific article published on 22 February 2005

Growth hormone and the metabolic syndrome.

scientific article

Growth hormone therapy and fracture risk in the growth hormone-deficient adult.

scientific article

Growth hormone treatment reduces abdominal visceral fat in postmenopausal women with abdominal obesity: a 12-month placebo-controlled trial.

scientific article published on 14 December 2004

Health Care Burden in Patients With Adrenal Insufficiency

scientific article published on 12 April 2017

Higher glucocorticoid replacement doses are associated with increased mortality in patients with pituitary adenoma.

scientific article

Hippocampal volumes in patients exposed to low-dose radiation to the basal brain. A case-control study in long-term survivors from cancer in the head and neck region.

scientific article published on 29 November 2012

Hypopituitarism

scientific article published on 31 March 2016

Impact of Acute and Chronic Low-Dose Glucocorticoids on Protein Metabolism

scientific article published on 24 July 2007

Impact of growth hormone and dehydroepiandrosterone on protein metabolism in glucocorticoid-treated patients.

scientific article published on 8 January 2008

Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation.

scientific article published on 23 November 2011

Improving glucocorticoid replacement in patients with adrenal insufficiency.

scientific article

Improving outcomes in patients with adrenal insufficiency: a review of current and future treatments

scientific article published on 09 June 2014

Incidence of malignant tumours in patients with a non-functioning pituitary adenoma.

scientific article

Incidence, prevalence and seasonal onset variation of Addison's disease among persons with type 1 diabetes mellitus: nationwide, matched cohort studies

scientific article published on 24 October 2017

Increased Orderliness of Growth Hormone (GH) Secretion in GH-Deficient Adults with Low Serum Insulin-Like Growth Factor I

scientific article published on 01 June 2002

Increased cardiovascular risk in South African patients with Addison's disease

scientific article published on 5 August 2013

Increased neck soft tissue mass and worsening of obstructive sleep apnea after growth hormone treatment in men with abdominal obesity

scientific article

Independent and combined effects of testosterone and growth hormone on extracellular water in hypopituitary men.

scientific article published on 12 April 2005

Influence of the Exon 3-Deleted/Full-Length Growth Hormone (GH) Receptor Polymorphism on the Response to GH Replacement Therapy in Adults with Severe GH Deficiency

scientific article published on 02 December 2008

Intima-media thickness in cardiovascularly asymptomatic hypopituitary adults with growth hormone deficiency: relation to body mass index, gender, and other cardiovascular risk factors.

scientific article published in December 2002

Investigation of glucocorticoid receptor polymorphisms in relation to metabolic parameters in Addison's disease

scientific article published on 15 February 2013

Is the somatotropic axis related to sympathetic nerve activity in healthy ageing men?

scientific article published on 01 November 2001

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

scientific article published on 23 June 2009

Life expectancy in patients with pituitary adenoma receiving growth hormone replacement.

scientific article

Lipids, blood pressure and bone metabolism after growth hormone therapy in elderly hemodialysis patients

scientific article published on 01 March 2003

Long-Acting Growth Hormone for Replacement Therapy

scientific article published on 01 June 2011

Long-term monitoring of insulin-like growth factor I in adult growth hormone deficiency: a critical appraisal.

scientific article

Long-term outcome and MGMT as a predictive marker in 24 patients with atypical pituitary adenomas and pituitary carcinomas given treatment with temozolomide.

scientific article published on 3 February 2015

Long-term safety of once-daily, dual-release hydrocortisone in patients with adrenal insufficiency: a phase 3b, open-label, extension study

scientific article published on 14 March 2017

Low birth size and final height predict high sympathetic nerve activity in adulthood.

scientific article published in June 2004

Low dose dehydroepiandrosterone affects behavior in hypopituitary androgen-deficient women: a placebo-controlled trial.

scientific article

MECHANISMS IN ENDOCRINOLOGY: Clinical and pharmacogenetic aspects of the growth hormone receptor polymorphism.

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MECHANISMS IN ENDOCRINOLOGY: Cushing's syndrome causes irreversible effects on the human brain: a systematic review of structural and functional magnetic resonance imaging studies

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Malignant disease and cardiovascular morbidity in hypopituitary adults with or without growth hormone replacement therapy.

scientific article published in July 2004

Management of adult growth hormone deficiency.

scientific article published on March 2007

Management of growth hormone deficiency in adults.

scientific article published on 12 July 2007

Management of the child born small for gestational age through to adulthood: a consensus statement of the International Societies of Pediatric Endocrinology and the Growth Hormone Research Society.

scientific article

Mean Expected Error in Prediction of Total Body Water: A True Accuracy Comparison between Bioimpedance Spectroscopy and Single Frequency Regression Equations

scientific article published on 2 June 2015

Meeting Reports: The 25th Anniversary of the Growth Hormone Research Society Lisbon, Portugal, May 20, 2017.

scientific article published in September 2017

Metabolic Effects of Cortisone Acetate vs Hydrocortisone in Patients With Secondary Adrenal Insufficiency

scientific article published on 29 October 2020

Models to predict changes in serum IGF1 and body composition in response to GH replacement therapy in GH-deficient adults.

scientific article published on 9 February 2010

Modulatory Effect of Raloxifene and Estrogen on the Metabolic Action of Growth Hormone in Hypopituitary Women.

scientific article published in April 2010

More focus on hyponatremia--a neglected clinical problem

scientific article published in April 2012

Multi-centre phase IV trial to investigate the immunogenicity of a new liquid formulation of recombinant human growth hormone in adults with growth hormone deficiency

scientific article published on 27 February 2018

Muscle strength in elderly adults with GH deficiency after 10 years of GH replacement

scientific article published on 12 May 2010

Neurodegenerative and inflammatory biomarkers in cerebrospinal fluid in patients with Cushing's syndrome in remission

scientific article

Nonfatal Stroke, Cardiac Disease, and Diabetes Mellitus in Hypopituitary Patients on Hormone Replacement Including Growth Hormone

scientific article published on 10 July 2007

Once-weekly Somapacitan is Effective and Well Tolerated in Adults with GH Deficiency: A Randomized Phase 3 Trial

scientific article published on 01 April 2020

Personalized approach to growth hormone replacement in adults

scientific article published on 01 November 2019

Prevalence and treatment of central hypogonadism and hypoandrogenism in women with hypopituitarism

scientific article published on 01 October 2018

Prevalence of primary aldosteronism among patients with type 2 diabetes.

scientific article

Primary Adrenal Insufficiency: Managing Mineralocorticoid Replacement Therapy

scientific article published on 15 November 2017

Primary aldosteronism and thyroid disorders in atrial fibrillation: A Swedish nationwide case-control study

scientific article published in January 2018

Proposal of a clinical response score and predictors of clinical response to 2 years of GH replacement therapy in adult GH deficiency

scientific article published on 14 September 2015

Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency

scientific article

Pseudoacromegaly: A Differential Diagnostic Problem for Acromegaly With a Genetic Solution

scientific article published on 14 July 2017

Rapid and high throughput genotyping of the growth hormone receptor exon 3 deleted/full-length polymorphism using a tagSNP.

scientific article published on 9 March 2010

Reduced DNA methylation and psychopathology following endogenous hypercortisolism - a genome-wide study

scientific article published on 16 March 2017

Regulating of growth hormone sensitivity by sex steroids: implications for therapy.

scientific article published on January 2006

Replacement therapy of oral hydrocortisone in adrenal insufficiency: the influence of gastrointestinal factors

scientific article published on 01 June 2008

Reviewing the safety of GH replacement therapy in adults

scientific article published on 19 June 2015

Robustness study of the different immittance spectra and frequency ranges in bioimpedance spectroscopy analysis for assessment of total body composition.

scientific article published on 22 May 2014

Role of the GH/IGF-1 axis in lifespan and healthspan: lessons from animal models.

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SNPs within the GH-signaling pathway are associated with the early IGF1 response to GH replacement therapy in GHD adults.

scientific article published on 25 November 2013

Safety aspects of growth hormone replacement in adults.

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Salivary Cortisol Day Curves in Addison’s Disease in Patients on Hydrocortisone Replacement

scientific article published on 14 August 2012

Salivary Cortisol and Cortisone do not Appear to be Useful Biomarkers for Monitoring Hydrocortisone Replacement in Addison's Disease.

scientific article published on 3 November 2016

Saving lives of patients with adrenal insufficiency: a pan-European initiative?

scientific article published on 12 January 2014

Serum cortisol and vitamin D status are independently associated with blood pressure in pregnancy

scientific article published on 30 January 2019

Seven years of growth hormone (GH) replacement improves quality of life in hypopituitary patients with adult-onset GH deficiency.

scientific article

Sleep apnoea and quality of life in growth hormone (GH)-deficient adults before and after 6 months of GH replacement therapy.

scientific article published in July 2006

Slightly superior performance of bioimpedance spectroscopy over single frequency regression equations for assessment of total body water

scientific article published on August 2015

Sympathetic Neural Burst Amplitude Distribution

scientific article published on 01 October 2000

Systematic review of surgery and outcomes in patients with primary aldosteronism

scientific article published on 20 January 2015

Ten Years of Growth Hormone (GH) Replacement Normalizes Muscle Strength in GH-Deficient Adults

scientific article published on 16 December 2008

The GH receptor exon 3 deleted/full-length polymorphism is associated with central adiposity in the general population

scientific article

The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerations

scientific article published on 09 April 2013

The Impact of Glucocorticoid Replacement on Bone Mineral Density in Patients With Hypopituitarism Before and After 2 Years of Growth Hormone Replacement Therapy

scientific article published on 13 January 2014

The Prevalence of Celiac Disease in Blood Donors in Iceland

scientific article published on 04 July 2008

The aging population--is there a role for endocrine interventions?

scientific article

The cardiovascular risk reduction benefits of a low-carbohydrate diet outweigh the potential increase in LDL-cholesterol.

scientific article published on 9 February 2016

The consequences of discontinuing GH after linear growth is completed.

scientific article published in May 2002

The effects of five-year growth hormone replacement therapy on muscle strength in elderly hypopituitary patients

scientific article published on 01 January 2005

The growth hormone receptor exon 3-deleted/full-length polymorphism and response to growth hormone therapy in prepubertal idiopathic short children

scientific article

The impact of adjustments to the diagnostic criteria for biochemical remission in surgically treated patients with acromegaly

scientific article published on 24 August 2017

The impact of glucocorticoid replacement regimens on metabolic outcome and comorbidity in hypopituitary patients.

scientific article published on 8 August 2006

The liquorice effect on the RAAS differs between the genders

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The metabolic consequences of thyroxine replacement in adult hypopituitary patients.

scientific article published in December 2012

The metabolic syndrome and its components in 178 patients treated for craniopharyngioma after 16 years of follow-up.

scientific article published on 7 September 2017

The relationship between glucocorticoid replacement and quality of life in 2737 hypopituitary patients.

scientific article published on 15 August 2014

Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe.

scientific article published on 21 October 2013

Three-years of growth hormone (GH) replacement therapy in GH-deficient adults: effects on quality of life, patient-reported outcomes and healthcare consumption.

scientific article published in June 2004

Treatment of Growth Hormone Deficiency in Adults

scientific article published on 21 January 2009

Treatment of Obese Subjects with the Oral Growth Hormone Secretagogue MK-677 Affects Serum Concentrations of Several Lipoproteins, But Not Lipoprotein(a)

scientific article published on 01 June 1999

Tumour recurrence and enlargement in patients with craniopharyngioma with and without GH replacement therapy during more than 10 years of follow-up.

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Turning back the clock on adrenal insufficiency.

scientific article published on 8 December 2017

Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients With Addison's Disease: A Case-Control Study

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[Primary aldosteronism is an underdiagnosed cause of hypertension. Important to find undiagnosed patients--effective treatment available]