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List of works by Gwyn W Gould

16K Fractionation of 3T3-L1 Adipocytes to Produce a Crude GLUT4-Containing Vesicle Fraction

scientific article published on March 2016

3T3-L1 adipocytes express two isoforms of phospholipase D in distinct subcellular compartments.

scientific article published on January 1999

5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.

scientific article published on October 2000

A complex network of interactions between mitotic kinases, phosphatases and ESCRT proteins regulates septation and membrane trafficking in S. pombe

scientific article

A fast passive Ca2+ efflux mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles

scientific article published on 01 November 1987

A kinetic model for Ca2+ efflux mediated by the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum

scientific article published on August 1987

A kinetic model for the Ca2+ + Mg2+-activated ATPase of sarcoplasmic reticulum

scientific article published on July 1986

A model for the uptake and release of Ca2+ by sarcoplasmic reticulum

scientific article published on August 1987

A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor-stimulated bovine airway smooth-muscle cells

scientific article published on September 1996

A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome

scientific article published in July 2002

ACRP30 is secreted from 3T3-L1 adipocytes via a Rab11-dependent pathway.

scientific article

Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

scientific article

Adipsin and the glucose transporter GLUT4 traffic to the cell surface via independent pathways in adipocytes

scientific article

Agonist-dependent, cholera toxin-catalyzed ADP-ribosylation of pertussis toxin-sensitive G-proteins following transfection of the human alpha 2-C10 adrenergic receptor into rat 1 fibroblasts. Evidence for the direct interaction of a single receptor w

scientific article published in Journal of Biological Chemistry

Altered vascular function in young women with polycystic ovary syndrome

scientific article published on February 2002

Alternative routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4.

scientific article

Analysis of amino and carboxy terminal GLUT-4 targeting motifs in 3T3-L1 adipocytes using an endosomal ablation technique

scientific article

Analysis of the Glucose Transporter Compliment of Metabolically Important Tissues from the Milan Hypertensive Rat

scientific article published on 01 June 1995

Analysis of the co-localization of the insulin-responsive glucose transporter (GLUT4) and the trans Golgi network marker TGN38 within 3T3-L1 adipocytes

scientific article published on June 1994

Analysis of the glucose transporter content of islet cell lines: implications for glucose-stimulated insulin release

scientific article published on November 1992

Analysis of the structural requirements of sugar binding to the liver, brain and insulin-responsive glucose transporters expressed in oocytes

scientific article published on September 1993

Animal cell cytokinesis: The role of dynamic changes in the plasma membrane proteome and lipidome

scientific article published on 22 December 2015

Arfophilins are dual Arf/Rab 11 binding proteins that regulate recycling endosome distribution and are related to Drosophila nuclear fallout

scientific article published on 17 April 2003

Breaking up is hard to do - membrane traffic in cytokinesis.

scientific article published on May 2008

CD36 deficiency and insulin resistance

scientific article published in The Lancet

CHC22 clathrin mediates traffic from early secretory compartments for human GLUT4 pathway biogenesis

scientific article published on 01 January 2020

Cardiac SNARE Expression in Health and Disease

scientific article published on 19 December 2019

Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat.

scientific article

Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes

scientific article published on 05 March 2020

Characterisation of proteins associated with the GLUT4 intracellular compartment

scientific article published on August 1997

Characterization of Ca2+ uptake and release by vesicles of skeletal-muscle sarcoplasmic reticulum

scientific article published on August 1987

Characterization of VAMP isoforms in 3T3-L1 adipocytes: implications for GLUT4 trafficking.

scientific article

Characterization of the ileal Na+/bile salt co-transporter in brush border membrane vesicles and functional expression in Xenopus laevis oocytes

scientific article published on August 1992

Characterization of the intracellular signalling pathways that underlie growth-factor-stimulated glucose transport in Xenopus oocytes: evidence for ras- and rho-dependent pathways of phosphatidylinositol 3-kinase activation

scientific article published on August 1997

Characterization of two distinct binding modes between syntaxin 4 and Munc18c

scientific article published on 01 May 2009

Characterization of vesicles containing insulin-responsive intracellular glucose transporters isolated from 3T3-L1 adipocytes by an improved procedure

scientific article published on October 1988

Comparison of phosphatidylethanolamine and phosphatidylcholine vesicles produced by treating cholate-phospholipid micelles with cholestyramine

scientific article published on 01 July 1989

Compartment ablation analysis of the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 adipocytes

scientific article

Compartment-ablation studies of GLUT4 distribution in adipocytes: evidence for multiple intracellular pools

scientific article published on August 1997

Complete Membrane Fractionation of 3T3-L1 Adipocytes

scientific article published on February 2016

Conflicting evidence for the role of JNK as a target in breast cancer cell proliferation: Comparisons between pharmacological inhibition and selective shRNA knockdown approaches

scientific article published in February 2018

Cyclic AMP Inhibits PDGF-stimulated Mitogen-activated Protein Kinase Activity in Rat Aortic Smooth Muscle Cells via Inactivation of c-Raf-1 Kinase and Induction of MAP Kinase Phosphatase-1

scientific article published on 01 May 1997

Decreased insulin sensitivity during dietary sodium restriction is not mediated by effects of angiotensin II on insulin action.

scientific article published in August 2003

Development of insulin sensitivity in rat skeletal muscle. Studies of glucose transporter and insulin receptor mRNA levels

scientific article

Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3-L1 adipocytes

scientific article published on November 1999

Differential targeting of glucose transporter isoforms heterologously expressed in Xenopus oocytes

scientific article published on March 1993

Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

scientific article

Distribution of GLUT3 glucose transporter protein in human tissues

scientific article published in October 1992

Dynamics of insulin-stimulated translocation of GLUT4 in single living cells visualised using green fluorescent protein

article

EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes

scientific article published in 2022

ESCRT function in cytokinesis: location, dynamics and regulation by mitotic kinases

scientific article

Effects of diet on the function of sarcoplasmic reticulum

scientific article published on August 1987

Effects of insulin on intracellular GLUT4 vesicles in adipocytes: evidence for a secretory mode of regulation

scientific article

Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells

scientific article published on September 1996

Evidence for a role for ADP-ribosylation factor 6 in insulin-stimulated glucose transporter-4 (GLUT4) trafficking in 3T3-L1 adipocytes

scientific article published on June 1999

Evidence for a role of phosphatidylinositol 3-kinase in the regulation of glucose transport in Xenopus oocytes.

scientific article published in October 1994

Evidence for a role of the exocyst in insulin-stimulated Glut4 trafficking in 3T3-L1 adipocytes.

scientific article published on 17 November 2004

Evidence for ras- and rho-dependent pathways in the regulation of glucose transport by growth factors

scientific article published in August 1997

Evidence that Thrombin-stimulated DNA Synthesis in Pulmonary Arterial Fibroblasts Involves Phosphatidylinositol 3-kinase-dependent p70 Ribosomal S6 Kinase Activation

article

Examination of the glycosidation state of five members of the human facilitative glucose transporter family

scientific article published on August 1992

Exocyst proteins in cytokinesis: Regulation by Rab11.

scientific article published on November 2013

Expression of a functional glucose transporter in Xenopus oocytes

scientific article published on 01 November 1989

Expression of c-raf-1 and A-raf-1 during differentiation of 3T3-L1 preadipocyte fibroblasts into adipocytes

scientific article published on August 1989

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice

scientific article published on April 1992

Expression of the liver-type glucose transporter (GLUT2) in 3T3-L1 adipocytes: analysis of the effects of insulin on subcellular distribution

scientific article published on November 1994

Fructose transport and metabolism in adipose tissue of Zucker rats: diminished GLUT5 activity during obesity and insulin resistance

scientific article

Functional studies of human GLUT5: effect of pH on substrate selection and an analysis of substrate interactions

scientific article published in September 1997

GLUT4 expression and glucose transport in human induced pluripotent stem cell-derived cardiomyocytes

scientific article published on 25 July 2019

GLUT4 vesicle dynamics in living 3T3 L1 adipocytes visualized with green-fluorescent protein

scientific article published on November 1997

Genetic and Cytological Methods to Study ESCRT Cell Cycle Function in Fission Yeast

scientific article published on 01 January 2019

Glucose transporters in rat peripheral nerve: Paranodal expression of GLUT1 and GLUT3

scientific article published on 01 December 1996

Growth factor-induced stimulation of hexose transport in 3T3-L1 adipocytes: evidence that insulin-induced translocation of GLUT4 is independent of activation of MAP kinase.

scientific article published on March 1994

Growth factors, mitogens, oncogenes and the regulation of glucose transport

scientific article

Hormonal regulation of the insulin-responsive glucose transporter, GLUT4: some recent advances.

scientific article published on March 1996

Human intestinal glucose transporter expression and localization of GLUT5.

scientific article published in March 1992

Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation

scientific article published in October 1992

Hypothalamic GLUT 4 expression: a glucose- and insulin-sensing mechanism?

scientific article

Hypoxic Stimulation of the Stress-activated Protein Kinases in Pulmonary Artery Fibroblasts

article

IKKepsilon: a kinase at the intersection of signaling and membrane traffic.

scientific article published on 14 June 2011

Identification of further important residues within the Glut4 carboxy-terminal tail which regulate subcellular trafficking

scientific article published on September 2000

Immunological analysis of glucose transporters expressed in different regions of the rat brain and central nervous system

scientific article published in May 1993

Immunological identification of five members of the human facilitative glucose transporter family

scientific article published in August 1992

Insect renal tubules constitute a cell-autonomous immune system that protects the organism against bacterial infection

scientific article published on 31 March 2005

Insulin and platelet-derived growth factor acutely stimulate glucose transport in 3T3-L1 fibroblasts independently of protein kinase C.

scientific article

Insulin resistance in diabetes mellitus. Defective insulin-regulatable glucose transport plays an important role

scientific article published on 01 April 1995

Insulin stimulated GLUT4 translocation - Size is not everything!

scientific article published on 14 March 2020

Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism

scientific journal article

Insulin-induced translocation of glucose transporters to the plasma membrane precedes full stimulation of hexose transport

scientific article published on September 1988

Insulin-stimulated translocation of the HepG2/erythrocyte-type glucose transporter expressed in 3T3-L1 adipocytes

scientific article

Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.

scientific article published on July 1999

Iodixanol Gradient Centrifugation to Separate Components of the Low-Density Membrane Fraction from 3T3-L1 Adipocytes

scientific article published on February 2016

Large scale, single-cell FRET-based glucose uptake measurements within heterogeneous populations

scientific article published on 03 March 2022

Long-term insulin treatment of 3T3-L1 adipocytes results in mis-targeting of GLUT4: implications for insulin-stimulated glucose transport.

scientific article published on October 2000

Low grade chronic inflammation in women with polycystic ovarian syndrome

scientific article published in June 2001

Lysophosphatidic acid stimulates glucose transport in Xenopus oocytes via a phosphatidylinositol 3'-kinase with distinct properties

scientific article published on May 1996

MAP kinase may play a role in the early phase of glucose transport in insulin treated 3T3-L1 fibroblasts

scientific article published on November 1993

Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis

scientific article

Mitogen-activated protein kinase (MAP kinase), MAP kinase kinase and c-Mos stimulate glucose transport in Xenopus oocytes

scientific article published on October 1993

Mutational analysis of the carboxy-terminal phosphorylation site of GLUT-4 in 3T3-L1 adipocytes

scientific article published on September 1998

Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitro

scientific article

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).

scientific article published on 12 March 2012

P2Y receptor-mediated inhibition of tumor necrosis factor alpha -stimulated stress-activated protein kinase activity in EAhy926 endothelial cells

scientific article

Pancreatic beta-cells express a low affinity glucose transporter: functional consequences in normal and diabetic states

scientific article

Phenylarsine oxide stimulates hexose transport in 3T3-L1 adipocytes by a mechanism other than an increase in surface transporters

scientific article

Phorbol ester only partially mimics the effects of insulin on glucose transport and glucose-transporter distribution in 3T3-L1 adipocytes

scientific article published on April 1991

Phosphatidylinositol 3′-kinase, But Not p70 Ribosomal S6 Kinase, Is Involved in Membrane Protein Recycling: Wortmannin Inhibits Glucose Transport and Downregulates Cell-Surface Transferrin Receptor Numbers Independently of Any Effect on Fluid-phase

scientific article published on 01 June 1996

Preparation of a Total Membrane Fraction from 3T3-L1 Adipocytes

scientific article published on March 2016

Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487.

scientific article published on 26 October 2016

Proximity Ligation Assay to Study the GLUT4 Membrane Trafficking Machinery

scientific article published in January 2018

Quantification of SNARE protein levels in 3T3-L1 adipocytes: implications for insulin-stimulated glucose transport

scientific article published on April 2000

Reduced insulin-stimulated GLUT4 bioavailability in stroke-prone spontaneously hypertensive rats

scientific article

Regulation of caveolar endocytosis by syntaxin 6-dependent delivery of membrane components to the cell surface

scientific article

Regulation of endothelin-1- and lysophosphatidic acid-stimulated tyrosine phosphorylation of focal adhesion kinase (pp125fak) in Rat-1 fibroblasts

scientific article published on July 1994

Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of mitogen-activated protein kinase by protein kinase C- and pertussis toxin-dependent pathways in the endothelial cell line EAhy 926.

scientific article published on May 1995

Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of pp42 mitogen-activated protein kinase by protein kinase C and protein kinase A in EAhy926 cells

scientific article

Regulation of protein phosphorylation by insulin and an insulinomimetic oligosaccharide in 3T3-L1 adipocytes and Fao hepatoma cells

scientific article published on June 1988

Role of endosomal Rab GTPases in cytokinesis.

scientific article published on 8 December 2006

Role of receptor desensitization, phosphatase induction and intracellular cyclic AMP in the termination of mitogen-activated protein kinase activity in UTP-stimulated EAhy 926 endothelial cells

scientific article published on April 1996

Role of the adenylate cyclase, phosphoinositidase C and receptor tyrosyl kinase systems in the control of hepatocyte proliferation by hepatocyte growth factor

scientific article published on 01 September 1992

SNARE phosphorylation: a control mechanism for insulin-stimulated glucose transport and other regulated exocytic events.

scientific article published on 3 November 2017

SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis.

scientific article published in May 2001

SNARE proteins underpin insulin-regulated GLUT4 traffic.

scientific article published on 08 February 2011

Sex hormones induce insulin resistance in 3T3-L1 adipocytes by reducing cellular content of IRS proteins.

scientific article published on November 2000

Should sperm donors be paid? A survey of the attitudes of the general public

scientific article published in March 1998

Silver ions trigger Ca2+ release by interaction with the (Ca2+-Mg2+)-ATPase in reconstituted systems.

scientific article

Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin

scientific article published in September 2001

Sorting of GLUT4 into its insulin-sensitive store requires the Sec1/Munc18 protein mVps45

scientific article published on 05 June 2013

Stimulation by the nucleotides, ATP and UTP of mitogen-activated protein kinase in EAhy 926 endothelial cells

scientific article published on March 1996

Stress-activated protein kinases: activation, regulation and function.

scientific article published on September 1997

Structure and function of mammalian facilitative sugar transporters.

scientific article

Structure-function analysis of liver-type (GLUT2) and brain-type (GLUT3) glucose transporters: expression of chimeric transporters in Xenopus oocytes suggests an important role for putative transmembrane helix 7 in determining substrate selectivity.

scientific article

Structure-function studies of the brain-type glucose transporter, GLUT3: alanine-scanning mutagenesis of putative transmembrane helix 8.

scientific article published in August 1997

Structure-function studies of the brain-type glucose transporter, GLUT3: alanine-scanning mutagenesis of putative transmembrane helix VIII and an investigation of the role of proline residues in transport catalysis

scientific article published in May 1997

Studies of the regulated assembly of SNARE complexes in adipocytes.

scientific article

Sugar transporters from bacteria, parasites and mammals: structure-activity relationships

scientific article

Syntaxin 16 controls the intracellular sequestration of GLUT4 in 3T3-L1 adipocytes

scientific article published on 30 June 2006

Syntaxin 16 is a master recruitment factor for cytokinesis

scientific article published on 9 October 2013

Syntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.

scientific article published on 4 April 2003

The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis.

scientific article

The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

scientific article published on 24 July 2019

The SNARE proteins SNAP-25 and SNAP-23 display different affinities for lipid rafts in PC12 cells. Regulation by distinct cysteine-rich domains

scientific article

The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis.

scientific article published on 23 January 2017

The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells

scientific article published on November 1995

The cytosolic C-terminus of the glucose transporter GLUT4 contains an acidic cluster endosomal targeting motif distal to the dileucine signal.

scientific article published on August 2000

The deubiquitinating enzyme USP25 binds tankyrase and regulates trafficking of the facilitative glucose transporter GLUT4 in adipocytes

scientific article published on 18 March 2019

The effects of insulin on the level and activity of the GLUT4 present in human adipose cells

scientific article published on June 1995

The glucose transporter GLUT4 and the aminopeptidase vp165 colocalise in tubulo-vesicular elements in adipocytes and cardiomyocytes

scientific article published on September 1997

The glucose transporter family: structure, function and tissue-specific expression.

scientific article

The mammalian facilitative glucose transporter (GLUT) family.

scientific article

The permissive effect of serum on the inhibition of mitogen-activated protein kinase by forskolin in vascular smooth muscle cells

scientific article published on 01 May 1995

The regulation of abscission by multi-protein complexes.

scientific article published on October 2011

The role of protein kinase C in activation and termination of mitogen-activated protein kinase activity in angiotensin II-stimulated rat aortic smooth-muscle cells

scientific article published on 01 February 1996

The synaptic vesicle protein, cysteine-string protein, is associated with the plasma membrane in 3T3-L1 adipocytes and interacts with syntaxin 4.

scientific article published on January 2001

The vesicle- and target-SNARE proteins that mediate Glut4 vesicle fusion are localized in detergent-insoluble lipid rafts present on distinct intracellular membranes

scientific article published on 9 October 2002

Tissue-specific expression of facilitative glucose transporters: a rationale

scientific article published on August 1, 1992

Trafficking of Glut4-green fluorescent protein chimaeras in 3T3-L1 adipocytes suggests distinct internalization mechanisms regulating cell surface glut4 levels.

scientific article published on December 1999

Trafficking, targeting and translocation of the insulin-responsive glucose transporter, GLUT4, in adipocytes

scientific article

Translocation of the brain-type glucose transporter largely accounts for insulin stimulation of glucose transport in BC3H-1 myocytes

scientific article published on August 1990

Treatment of vascular smooth muscle cells with antisense phosphorothioate oligodeoxynucleotides directed against p42 and p44 mitogen-activated protein kinases abolishes DNA synthesis in response to platelet-derived growth factor.

scientific article

Trypsin stimulates proteinase-activated receptor-2-dependent and -independent activation of mitogen-activated protein kinases

scientific article published on December 1996

Tumour necrosis factor stimulates stress-activated protein kinases and the inhibition of DNA synthesis in cultures of bovine aortic endothelial cells

scientific article published on July 1998

Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4

scientific article

Uptake at Ca2+ mediated by the (Ca2+ + Mg2+)-ATPase in reconstituted vesicles

scientific article published on 01 November 1987

Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes.

scientific article published on January 1998

Visualization of distinct patterns of subcellular redistribution of the thyrotropin-releasing hormone receptor-1 and gqalpha /G11alpha induced by agonist stimulation

scientific article published on June 1999

mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes.

scientific article

v- and t-SNARE protein expression in models of insulin resistance: normalization of glycemia by rosiglitazone treatment corrects overexpression of cellubrevin, vesicle-associated membrane protein-2, and syntaxin 4 in skeletal muscle of Zucker [...]

scientific article published in April 2000

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