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List of works by Yong-Yu Liu

3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells

scientific article published on 08 January 2014

A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis

scientific article

A role for ceramide in driving cancer cell resistance to doxorubicin.

scientific article published on February 2008

An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells

scientific article published on 19 December 2018

Biological activities of fusarochromanone: a potent anti-cancer agent

scientific article

Cellular stress response in Eca-109 cells inhibits apoptosis during early exposure to isorhamnetin

scientific article published in January 2012

Ceramide Glycosylation Catalyzed by Glucosylceramide Synthase and Cancer Drug Resistance ⬇️

scientific article published on January 1, 2013

Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells

scientific article

Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations

scientific article published on 23 October 2019

Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway

scientific article

Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway

scientific article published on 28 June 2011

Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy.

scientific article

Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase.

scientific article

Doxorubicin and MBO-asGCS oligonucleotide loaded lipid nanoparticles overcome multidrug resistance in adriamycin resistant ovarian cancer cells (NCI/ADR-RES).

scientific article

Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression

scientific article published on 24 July 2009

Evaluation of anticancer agents using flow cytometry analysis of cancer stem cells

scientific article

Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

scientific article published on January 1999

Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs

scientific article

Glucosylceramide synthase, a factor in modulating drug resistance, is overexpressed in metastatic breast carcinoma

scientific article

Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis

scientific article published on November 1999

Hepatic regeneration in insulin-like growth factor binding protein-1 transgenic mice

scientific article published on April 1999

Highly and moderately aggressive mouse ovarian cancer cell lines exhibit differential gene expression

scientific article published on 02 March 2016

In vivo survivors of transformed mouse ovarian surface epithelial cells display diverse phenotypes for gene expression and tumorigenicity

scientific article

Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo.

scientific article

Increased expression of low-affinity insulin receptor isoform and insulin/insulin-like growth factor-I hybrid receptors in term placenta from insulin-resistant women with gestational hypertension

scientific article published on 01 August 1996

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.

scientific article published on 10 August 2016

Limited density of an antigen presented by RMA-S cells requires B7-1/CD28 signaling to enhance T-cell immunity at the effector phase

scientific article

Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.

scientific article

Mixed backbone antisense glucosylceramide synthase oligonucleotide (MBO-asGCS) loaded solid lipid nanoparticles: In vitro characterization and reversal of multidrug resistance in NCI/ADR-RES cells ⬇️

scientific article published on September 15, 2010

Novel Peptidomimetics for Inhibition of HER2:HER3 Heterodimerization in HER2-Positive Breast Cancer

scientific article published on 6 November 2014

Oligonucleotides blocking glucosylceramide synthase expression selectively reverse drug resistance in cancer cells

scientific article published on 16 February 2004

Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models

scientific article

Peptide-based radioimmunoassay for the two isoforms of the human insulin receptor

scientific article published on April 1995

Resuscitating Wild-Type p53 Expression by Disrupting Ceramide Glycosylation: A Novel Approach to Target Mutant p53 Tumors ⬇️

scientific article published on 04 October 2011

Sphingolipids and expression regulation of genes in cancer.

scientific article published on 21 October 2010

Suppression of Glucosylceramide Synthase Restores p53-Dependent Apoptosis in Mutant p53 Cancer Cells ⬇️

scientific article published on January 28, 2011

Taxol-induced ceramide generation and apoptosis in human breast cancer cells

scientific article

The opposite effects of doxorubicin on bone marrow stem cells versus breast cancer stem cells depend on glucosylceramide synthase

scientific article

Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance

scientific article

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