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List of works by Chikara Furusawa

A generic mechanism for adaptive growth rate regulation

scientific article

Acceleration and suppression of resistance development by antibiotic combinations

scientific article published on 26 April 2017

Adaptation of Saccharomyces cerevisiae cells to high ethanol concentration and changes in fatty acid composition of membrane and cell size

scientific article

Adaptation to optimal cell growth through self-organized criticality

scientific article published on 15 May 2012

An evolutionary relationship between genetic variation and phenotypic fluctuation

scientific article published on 5 October 2005

An improved physico-chemical model of hybridization on high-density oligonucleotide microarrays.

scientific article

Analysis of adaptation to high ethanol concentration in Saccharomyces cerevisiae using DNA microarray

scientific article published on 6 January 2009

Analysis of fluctuation in protein abundance without promoter regulation based on Escherichia coli continuous culture

scientific article published on 9 February 2007

Analysis of metabolic network based on conservation of molecular structure

scientific article published on 10 September 2008

Analysis of stochasticity in promoter activation by using a dual-fluorescence reporter system.

scientific article published on 23 June 2009

ArtPathDesign: rational heterologous pathway design system for the production of nonnative metabolites

scientific article published on 9 May 2013

Bacterial transcriptome reorganization in thermal adaptive evolution

scientific article published on 16 October 2015

Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

scientific article published on September 2005

Comparative analysis of transcriptional responses to saline stress in the laboratory and brewing strains of Saccharomyces cerevisiae with DNA microarray

scientific article

Comparison of Sequence Reads Obtained from Three Next-Generation Sequencing Platforms ⬇️

scientific article published on May 17, 2011

Comparison of transcriptional responses to osmotic stresses induced by NaCl and sorbitol additions in Saccharomyces cerevisiae using DNA microarray

scientific article published in December 2006

Complex organization in multicellularity as a necessity in evolution

scientific article published in January 2000

Comprehensive phenotypic analysis for identification of genes affecting growth under ethanol stress in Saccharomyces cerevisiae

scientific article published on 13 November 2008

Comprehensive phenotypic analysis of single-gene deletion and overexpression strains of Saccharomyces cerevisiae

scientific article

Consistency principle in biological dynamical systems

scientific article published on 22 April 2008

Construction of a Genome-Scale Metabolic Model of Arthrospira platensis NIES-39 and Metabolic Design for Cyanobacterial Bioproduction

scientific article

Decoding gut microbiota by imaging analysis of fecal samples

scientific article published on 22 November 2021

Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

scientific article published on 3 August 2009

Development of a physical model-based algorithm for the detection of single-nucleotide substitutions by using tiling microarrays

scientific article

Development of an automated culture system for laboratory evolution.

scientific article

Dynamic change in promoter activation during lysine biosynthesis in Escherichia coli cells

scientific article published on 28 November 2007

Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum

scientific article

Emergence of multicellular organisms with dynamic differentiation and spatial pattern

scientific article published on 01 January 1998

Emergence of rules in cell society: differentiation, hierarchy, and stability

scientific article published in July 1998

Engineering strategy of yeast metabolism for higher alcohol production

scientific article published on 08 September 2011

Enhanced acetic acid and succinic acid production under microaerobic conditions by Corynebacterium glutamicum harboring Escherichia coli transhydrogenase gene pntAB.

scientific article published in January 2014

Epigenetic Feedback Regulation Accelerates Adaptation and Evolution ⬇️

scientific article published on May 8, 2013

Evaluating 13C enrichment data of free amino acids for precise metabolic flux analysis ⬇️

scientific article published on November 1, 2011

Evolutionary origin of power-laws in a biochemical reaction network: embedding the distribution of abundance into topology

scientific article published on 23 January 2006

Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays.

scientific article

Extracting the hidden features in saline osmotic tolerance in Saccharomyces cerevisiae from DNA microarray data using the self-organizing map: biosynthesis of amino acids

scientific article

FastPros: screening of reaction knockout strategies for metabolic engineering

scientific article

Genome-wide analysis of the effects of location and number of stress response elements on gene expression in Saccharomyces cerevisiae

scientific article published on 01 November 2008

Genome-wide expression analysis of Saccharomyces pastorianus orthologous genes using oligonucleotide microarrays

scientific article

Genome-wide identification of the targets for genetic manipulation to improve L-lactate production by Saccharomyces cerevisiae by using a single-gene deletion strain collection

scientific article published on 9 May 2013

Global change in Escherichia coli gene expression in initial stage of symbiosis with Dictyostelium cells

scientific article published in March 2004

Global relationships in fluctuation and response in adaptive evolution

scientific article

Global/temporal gene expression analysis of Escherichia coli in the early stages of symbiotic relationship development with the cellular slime mold Dictyostelium discoideum.

scientific article

High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli

scientific article published on 24 November 2020

Identification of target genes conferring ethanol stress tolerance to Saccharomyces cerevisiae based on DNA microarray data analysis

scientific article

Improvement of L-lactate production by CYB2 gene disruption in a recombinant Saccharomyces cerevisiae strain under low pH condition

scientific article

Improving protein secretion of a transglutaminase-secreting Corynebacterium glutamicum recombinant strain on the basis of 13C metabolic flux analysis

scientific article published on 08 September 2011

In silico screening of triple reaction knockout Escherichia coli strains for overproduction of useful metabolites

scientific article published on 3 October 2012

Increased 3-hydroxypropionic acid production from glycerol, by modification of central metabolism in Escherichia coli

scientific article

Integrated metabolic flux and omics analysis of Synechocystis sp. PCC 6803 under mixotrophic and photoheterotrophic conditions

scientific article published on 26 June 2014

Integrated transcriptomic and metabolomic analysis of the central metabolism of Synechocystis sp. PCC 6803 under different trophic conditions

scientific article published on 11 April 2013

Investigating the effectiveness of DNA microarray analysis for identifying the genes involved in l-lactate production by Saccharomyces cerevisiae

scientific article published in October 2009

Investigating the effects of perturbations to pgi and eno gene expression on central carbon metabolism in Escherichia coli using (13)C metabolic flux analysis

scientific article published on 21 June 2012

Investigation of phosphorylation status of OdhI protein during penicillin- and Tween 40-triggered glutamate overproduction by Corynebacterium glutamicum

scientific article published on 19 April 2011

Metabolic dynamics restricted by conserved carriers: Jamming and feedback.

scientific article published on 7 November 2017

Model-based analysis of non-specific binding for background correction of high-density oligonucleotide microarrays.

scientific article

Morphogenesis, plasticity and irreversibility

scientific article published in January 2006

Mutational property of newly identified mutagen l-glutamic acid γ-hydrazide in Escherichia coli

scientific article published in 2021

OpenMebius: an open source software for isotopically nonstationary 13C-based metabolic flux analysis.

scientific article

Origin of Complexity in Multicellular Organisms

scientific article

Oscillatory protein expression dynamics endows stem cells with robust differentiation potential

scientific article

Phenotypic convergence in bacterial adaptive evolution to ethanol stress

scientific article published on 3 September 2015

Pluripotency, Differentiation, and Reprogramming: A Gene Expression Dynamics Model with Epigenetic Feedback Regulation ⬇️

scientific article published on 26 August 2015

Precise metabolic flux analysis of coryneform bacteria by gas chromatography-mass spectrometry and verification by nuclear magnetic resonance

scientific article published in November 2006

Prediction of antibiotic resistance by gene expression profiles.

scientific article

Reconstruction and verification of a genome-scale metabolic model for Synechocystis sp. PCC6803

scientific article published on 01 September 2011

Relationship between noise characteristics in protein expressions and regulatory structures of amino acid biosynthesis pathways

scientific article published in January 2010

Relevance of phenotypic noise to adaptation and evolution

scientific article published in September 2008

Robust development as a consequence of generated positional information

scientific article published in October 2003

Saccharomyces cerevisiae and DNA microarray analyses: what did we learn from it for a better understanding and exploitation of yeast biotechnology?

scientific article published on 23 April 2010

Selection of initial conditions for recursive production of multicellular organisms

scientific article published on 01 December 2004

Single mutation makes Escherichia coli an insect mutualist

scientific article published in 2022

Stable disruption of ethanol production by deletion of the genes encoding alcohol dehydrogenase isozymes in Saccharomyces cerevisiae

scientific article published on 26 October 2011

Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis

scientific article published on 23 June 2007

Suppression of antibiotic resistance acquisition by combined use of antibiotics.

scientific article

Systems metabolic engineering: the creation of microbial cell factories by rational metabolic design and evolution

scientific article published on January 2013

The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells

scientific article

Theory of robustness of irreversible differentiation in a stem cell system: chaos hypothesis

scientific article published in April 2001

Toward understanding of evolutionary constraints: experimental and theoretical approaches

scientific article published on 22 June 2020

Transcriptome analysis of parallel-evolved Escherichia coli strains under ethanol stress

scientific article

Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution.

scientific article

Understanding the mechanism of heat stress tolerance caused by high trehalose accumulation in Saccharomyces cerevisiae using DNA microarray

scientific article published on 04 January 2012

Utilization of Saccharomyces cerevisiae recombinant strain incapable of both ethanol and glycerol biosynthesis for anaerobic bioproduction

scientific article published on 26 February 2013

Wickerhamiella bidentis sp. nov., a novel yeast species isolated from flowers and insects in Japan

scientific article published in 2023

Zipf's law in gene expression

scientific article published on 26 February 2003

¹³C-based metabolic flux analysis of Saccharomyces cerevisiae with a reduced Crabtree effect

scientific article published on 26 January 2015

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