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List of works by Ernest Arenas

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease

scientific article published on 28 June 2016

A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo

scientific journal article

A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway

scientific article

A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's disease

scientific article

Adenosine A1 receptor-mediated modulation of dopamine D1 receptors in stably cotransfected fibroblast cells

scientific article

Adenosine A2A receptors modulate the binding characteristics of dopamine D2 receptors in stably cotransfected fibroblast cells.

scientific article published on December 1996

Alpha-chemokines regulate proliferation, neurogenesis, and dopaminergic differentiation of ventral midbrain precursors and neurospheres

scientific journal article

An efficient method for the derivation of mouse embryonic stem cells.

scientific article published on 9 December 2005

Analysis of bioactive oxysterols in newborn mouse brain by LC/MS.

scientific article published on 13 August 2012

Analysis of neural crest-derived clones reveals novel aspects of facial development

scientific article

BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex

scientific article published in August 1998

BDNF up-regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia

scientific article published in April 1998

BMP-2 and cAMP elevation confer locus coeruleus neurons responsiveness to multiple neurotrophic factors

scientific article published on March 2002

BMPs, FGF8 and Wnts regulate the differentiation of locus coeruleus noradrenergic neuronal precursors

scientific article published in October 2006

Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways

scientific article published on 24 October 2008

Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.

scholarly article

Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis

scientific article

Brain-derived neurotrophic factor does not prevent ionizing radiation-induced apoptosis in the developing rat brain

scientific article published in November 1998

Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat.

scientific article published on March 2001

Brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in vivo

scientific article

Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease

scientific article

Ca2+ and cAMP signaling in human embryonic stem cell-derived dopamine neurons

scientific article published in September 2010

Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? ⬇️

scientific article published on 7 December 2009

Cholestenoic acids regulate motor neuron survival via liver X receptors

scientific article

Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host

scientific article

Complementary and overlapping expression of Y1, Y2 and Y5 receptors in the developing and adult mouse nervous system.

scientific article published in November 1998

Comprehensive cell atlas of the first-trimester developing human brain

scientific article published on 12 October 2023

Control of Neural Stem Cell Adhesion and Density by an Electronic Polymer Surface Switch

scientific article published on 01 December 2008

Control of tachykinin-evoked acetylcholine release from rat striatal slices by dopaminergic neurons

scientific article published on 01 November 1993

Cripto as a target for improving embryonic stem cell-based therapy in Parkinson's disease

scientific article published in April 2005

Crucial role of TrkB ligands in the survival and phenotypic differentiation of developing locus coeruleus noradrenergic neurons

scientific article published in August 2003

Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons.

scientific article published on 23 October 2013

Delayed dopaminergic neuron differentiation in Lrp6 mutant mice

scientific journal article

Derivation of mouse embryonic stem cells

scientific article published on 01 January 2006

Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse.

scientific article published in September 2015

Differential effects of glial cell line-derived neurotrophic factor and neurturin on developing and adult substantia nigra dopaminergic neurons

scientific article published on July 1999

Differential expression of Wnts after spinal cord contusion injury in adult rats

scientific article

Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

scientific journal article

Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease

scientific article published in November 1998

Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation

scientific article published on October 1993

Disruption of EphA/ephrin-a signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine

scientific article published in July 2004

Distinct roles of the Y1 and Y2 receptors on neuropeptide Y-induced sensitization to sedation.

scientific article

Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis

scientific journal article

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors

scientific article published on June 2016

Dopaminergic system mediates only delta-opiate inhibition of endogenous acetylcholine release evoked by glutamate from rat striatal slices

scientific article published in January 1991

Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain

scientific article published on 28 February 2006

Effect of opioids on acetylcholine release evoked by K+ or glutamic acid from rat neostriatal slices

scientific article published in July 1990

Effects of BDNF and NT-4/5 on striatonigral neuropeptides or nigral GABA neurons in vivo

scientific article

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

scientific article

Emerging roles of Wnts in the adult nervous system

scientific article published on 16 December 2009

Engineering a dopaminergic phenotype in stem/precursor cells: role of Nurr1, glia-derived signals, and Wnts.

scientific article

Excitatory amino acids release endogenous acetylcholine from rat striatal slices: Regulation by gamma-aminobutyric acid

scientific article published on 01 January 1990

Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area.

scientific article

Fibroblast growth factor-20 promotes the differentiation of Nurr1-overexpressing neural stem cells into tyrosine hydroxylase-positive neurons

scientific article

Fibroblast-like cells from rat plantar skin and neurotrophin-transfected 3T3 fibroblasts influence neurite growth from rat sensory neurons in vitro

scientific article published on September 2000

Foxa2: the rise and fall of dopamine neurons

scientific article

Function of Wnts in dopaminergic neuron development

scientific article published on January 2006

Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model

scientific article

Functional receptor for GDNF encoded by the c-ret proto-oncogene

scientific article published on June 1996

GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices

scientific article published in December 1990

GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo

scientific article published on December 1995

GDNF, a multispecific neurotrophic factor with potential therapeutic applications in neurodegenerative disorders.

scientific article published in July 1996

GSK-3beta inhibition/beta-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons

scientific journal article

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease

scientific article published on 27 April 2020

Genetic interaction between Lrp6 and Wnt5a during mouse development

scientific journal article

Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage

scientific article published on November 1996

Heterotrimeric G protein-dependent WNT-5A signaling to ERK1/2 mediates distinct aspects of microglia proinflammatory transformation

scientific article

Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation.

scientific article published on 9 January 2008

How to make a midbrain dopaminergic neuron

scientific article published on June 2015

Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice

scientific article

Identification of midbrain floor plate radial glia-like cells as dopaminergic progenitors

scientific article

Increased Wnt levels in the neural tube impair the function of adherens junctions during neurulation

scientific article

Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor.

scientific article published in April 2000

Increased survival of dopaminergic neurons in striatal grafts of fetal ventral mesencephalic cells exposed to neurotrophin-3 or glial cell line-derived neurotrophic factor

scientific article

Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes.

scientific article published on July 1999

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model

scientific article

Inhibition of JNK increases survival of transplanted dopamine neurons in Parkinsonian rats

scientific article published on 21 July 2006

Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs

scientific article

Inhibition of mitochondrial complex III blocks neuronal differentiation and maintains embryonic stem cell pluripotency

scientific article

Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons

scientific article published on July 2010

Intrastriatal grafting of a GDNF-producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo

scientific article published in January 1999

Involvement of nerve growth factor and its receptor in the regulation of the cholinergic function in aged rats

scientific article

Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration

scientific article published on 02 April 2015

Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells

scientific article

MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus

scientific article published in 2021

Microarray analyses support a role for Nurr1 in resistance to oxidative stress and neuronal differentiation in neural stem cells

scientific article published on 12 October 2006

Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model.

scientific article

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

scientific article published on October 2016

Molecular analysis of the midbrain dopaminergic niche during neurogenesis

scholarly article published 26 June 2017

Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for adult motor neurons

scientific article

NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells.

scientific article

Neostriatal dopaminergic terminals prevent the GABAergic involvement in the mu- and delta-opioid inhibition of KCl-evoked endogenous acetylcholine release

scientific article

Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum

scientific article published in May 1994

Nerve growth factor and its receptor are differentially modified by chronic naltrexone treatment during rat brain development

scientific article published in January 1993

Neural progenitor cells engineered to secrete GDNF show enhanced survival, neuronal differentiation and improve cognitive function following traumatic brain injury

scientific article published on April 2006

Neural progenitors organize in small-world networks to promote cell proliferation

scientific article

Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons

scientific journal article

Neurokinin receptors differentially mediate endogenous acetylcholine release evoked by tachykinins in the neostriatum.

scientific article published in August 1991

Neuropeptide Y alters sedation through a hypothalamic Y1-mediated mechanism

scientific article published in June 2001

Neuroprotection by GDNF-secreting stem cells in a Huntington's disease model: optical neuroimage tracking of brain-grafted cells.

scientific article

Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members

scientific article

Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease.

scientific article

Neurotrophin-3 prevents the death of adult central noradrenergic neurons in vivo

scientific article published on January 1994

Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion.

scientific article published in April 1993

Neurturin is a neuritogenic but not a survival factor for developing and adult central noradrenergic neurons

scientific article published on June 2002

Neurturin protects striatal projection neurons but not interneurons in a rat model of Huntington's disease

scientific article

Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP.

scientific article published on 22 August 2017

Normal feeding behavior, body weight and leptin response require the neuropeptide Y Y2 receptor.

scientific article published in October 1999

Novel isoforms of the TFIID subunit TAF4 modulate nuclear receptor-mediated transcriptional activity

scientific article published in December 2004

Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells.

scientific article

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system

scientific article published on June 2016

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

scientific article

Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling

scientific article

Peptide-presenting two-dimensional protein matrix on supported lipid bilayers: an efficient platform for cell adhesion

scientific article published on December 2007

Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease

scientific article published in October 2002

Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation

scientific journal article

RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule

retracted scientific article

Region-specific effects of glia on neuronal induction and differentiation with a focus on dopaminergic neurons

scientific article

Regulation of dopamine D2 receptor affinity by cholecystokinin octapeptide in fibroblast cells cotransfected with human CCKB and D2L receptor cDNAs

scientific article published on March 1996

Responses of rat trigeminal neurones to dental pulp cells or fibroblasts overexpressing neurotrophic factors in vitro

scientific article published on January 2003

SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells

scientific journal article

Selective resistance of tachykinin-responsive cholinergic neurons in the quinolinic acid lesioned neostriatum

scientific article published in February 1993

Spatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult rats

scientific article

Srebf1 Controls Midbrain Dopaminergic Neurogenesis

scientific article published on 01 May 2020

Stem cells in the treatment of Parkinson's disease.

scientific article

Stem-cell-based strategies for the treatment of Parkinson's disease

scientific article

Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington's disease

scientific article published on March 2002

Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells

scientific journal article

Targeted lipidomic analysis of oxysterols in the embryonic central nervous system

scientific article published on 27 March 2009

The Ryk receptor is expressed in glial and fibronectin-expressing cells after spinal cord injury

scientific article published on 9 May 2013

The antimicrobial peptide rCRAMP is present in the central nervous system of the rat.

scientific article

The beta-chemokines CCL2 and CCL7 are two novel differentiation factors for midbrain dopaminergic precursors and neurons

scientific article published on 8 March 2008

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo

scientific journal article

The p75 neurotrophin receptor interacts with multiple MAGE proteins

scientific article (publication date: 20 December 2002)

The tyrosine Y2502.39 in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled.

scientific article published on 28 June 2017

Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons

scientific journal article

Towards stem cell replacement therapies for Parkinson's disease

scientific article published on May 2010

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift.

scientific article published on 3 July 2018

Transcriptomic diversity of cell types across the adult human brain

scientific article published on 12 October 2023

Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease

scientific article

Transplantable midbrain dopamine neurons: a moving target

scientific article published on 06 January 2010

Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway

scientific article

Vang-like protein 2 and Rac1 interact to regulate adherens junctions

scientific article

Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion

scientific journal article

WNT unrelated activities in commercially available preparations of recombinant WNT3a.

scientific article

WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.

scientific article published on 28 August 2012

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis

scientific article published on 02 April 2019

Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease

scientific article

Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin

scientific journal article

Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism

scientific journal article

Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells.

scientific article

Wnt/β-Catenin Stimulation and Laminins Support Cardiovascular Cell Progenitor Expansion from Human Fetal Cardiac Mesenchymal Stromal Cells

scientific article published on 23 March 2016

Wnt2 regulates progenitor proliferation in the developing ventral midbrain

scientific journal article

Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells

scientific journal article

Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha.

scientific article published on 18 December 2008

Wnt5a regulates midbrain dopaminergic axon growth and guidance

scientific journal article

Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo

scientific journal article

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

scientific article

Wnts are expressed in the spinal cord of adult mice and are differentially induced after injury

scientific article published on March 2014

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