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List of works by Marie Wahren-Herlenius

3rd Nordic Meeting on Genetics and Pathogenesis of Inflammatory Diseases

article

A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block

scientific article published in November 2011

A possible genetic association with chronic fatigue in primary Sjögren's syndrome: a candidate gene study

scientific article published on 3 September 2013

A serologic marker for fetal risk of congenital heart block

scientific article published on 01 May 2002

A serology-based approach combined with clinical examination of 125 Ro/SSA-positive patients to define incidence and prevalence of subacute cutaneous lupus erythematosus

scientific article

A5.27 Ro52 Expression is a Prognostic Factor for Survival in B Cell Lymphoma

An update on the role of type I interferons in systemic lupus erythematosus and Sjögrenʼs syndrome

scientific article published on 01 September 2018

Analysis of B-cell epitopes of the Ro/SS-A autoantigen

scientific article

Anti-Ro/SSA autoantibody-positive women's experience of information given on the risk of congenital heart block.

scientific article published on 14 December 2015

Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface.

scientific article

Anti-Ro52 epitope mapping in inflammatory myopathies

Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model

scientific article published on 14 November 2011

Anti-Ro52/SSA antibody-exposed fetuses with prolonged atrioventricular time intervals show signs of decreased cardiac performance

scientific article published on 01 November 2009

Antibodies to amino acid 200-239 (p200) of Ro52 as serological markers for the risk of developing congenital heart block

scientific article published on 22 August 2008

Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren's syndrome in Scandinavian samples

scientific article published on 30 January 2012

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.

scientific article

Association of genes in the NF-κB pathway with antibody-positive primary Sjögren's syndrome

scientific article published in November 2013

Augmented Th17 differentiation in Trim21 deficiency promotes a stable phenotype of atherosclerotic plaques with high collagen content

scientific article published on 4 September 2017

Autoantibodies to the functionally active RING-domain of Ro52/SSA are associated with disease activity in patients with lupus

Benefits of fetal echocardiographic surveillance in pregnancies at risk of congenital heart block: single-center study of 212 anti-Ro52-positive pregnancies

scientific article published on 07 June 2019

Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome

scientific article published in November 2003

Cigarette smoking patterns preceding primary Sjögren's syndrome

scientific article published on 01 September 2020

Clinical associations and expression pattern of the autoimmunity susceptibility factor DIORA-1 in patients with primary Sjögren's syndrome

scientific article published on 17 July 2018

Clinical follow-up of 102 anti-Ro/SSA-positive patients with dermatological manifestations

scientific article published on 01 January 2008

Cloning and characterization of two human Ro52-specific monoclonal autoantibodies directed towards a domain associated with congenital heart block

scientific article

Comorbidity and long-term outcome in patients with congenital heart block and their siblings exposed to Ro/SSA autoantibodies in utero

scientific article published on 26 February 2019

Concomitant Ro/SSA and La/SSB antibodies are biomarkers for the risk of venous thromboembolism and cerebral infarction in primary Sjögren's syndrome

scientific article published on 17 June 2019

Congenital heart block: evidence for a pathogenic role of maternal autoantibodies

scientific article

Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].

scientific article published on 28 November 2017

Cutaneous lupus erythematosus: clinical aspects and molecular pathogenesis.

scientific article published on 15 March 2013

Detection of anti-Ro/SSA and anti-La/SSB autoantibody-producing cells in salivary glands from patients with Sjögren's syndrome

scientific article published on 01 December 1998

Detection of antigen specific B-cells in tissues

scientific article published on 01 January 2007

Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies.

scientific article

Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern

article

Development of systemic lupus erythematosus in a patient with congenital heart block

article

Diagnostic precision of Doppler flow echocardiography in fetuses at risk for atrioventricular block

scientific article published on 01 November 2010

Difference in clinical presentation between women and men in incident primary Sjögren's syndrome

scientific article

Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis

scientific article published on January 2006

Diminished CXCR5 expression in peripheral blood of patients with Sjögren's syndrome may relate to both genotype and salivary gland homing

scientific article published on 17 February 2018

Doppler echocardiographic and electrocardiographic atrioventricular time intervals in newborn infants: evaluation of techniques for surveillance of fetuses at risk for congenital heart block

scientific article published on 01 July 2006

Doppler echocardiographic isovolumetric time intervals in diagnosis of fetal blocked atrial bigeminy and 2:1 atrioventricular block

scientific article published on 27 June 2014

Ductal epithelial expression of Ro52 correlates with inflammation in salivary glands of patients with primary Sjögren's syndrome

article published in 2014

E3 ubiquitin-protein ligase TRIM21-mediated lysine capture by UBE2E1 reveals substrate-targeting mode of a ubiquitin-conjugating E2

scientific article published on 03 June 2019

Early Resistance of Non-virulent Mycobacterial Infection in C57BL/6 Mice Is Associated With Rapid Up-Regulation of Antimicrobial Cathelicidin

scientific article published on 03 September 2018

Effects of maternal medication on long-term outcome in congenital heart block remain to be established. Response to: 'Comorbidity and long-term outcome in patients with congenital heart block and their siblings exposed to Ro/SSA autoantibodies in ut

scientific article published on 04 July 2019

Enhanced interferon regulatory factor 3 binding to the interleukin-23p19 promoter correlates with enhanced interleukin-23 expression in systemic lupus erythematosus.

scientific article

Environmental and lifestyle factors influencing risk of congenital heart block during pregnancy in anti-Ro/SSA-positive women

scientific article published on 7 September 2017

Environmental factors in the pathogenesis of primary Sjögren's syndrome

scientific article published on 27 February 2020

Epidemiological profile and north-south gradient driving baseline systemic involvement of primary Sjögren's syndrome

scientific article published on 24 December 2019

Erratum to: Interferon activation status underlies higher antibody response to viral antigens in patients with SLE receiving no or light treatment

scientific article published on 29 December 2020

European families reveal MHC class I and II associations with autoimmune-mediated congenital heart block

scientific article published on 16 February 2018

Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjögren's syndrome

scientific article published on 01 April 2002

Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors

scientific article published on 23 August 2013

Factors influencing fetal cardiac conduction in anti-Ro/SSA-positive pregnancies

scientific article published in October 2017

Fine specificity of the Ro/SSA autoantibody response in relation to serological and clinical findings in 96 patients with self-reported cutaneous symptoms induced by the sun

scientific article published on 01 January 2007

FoxP3+ CXCR5+ CD4+ T cell frequencies are increased in peripheral blood of patients with primary Sjögren's syndrome

scientific article published on 10 January 2019

Gene-environment interaction in induction of autoimmunity

article

Genetic and clinical basis for two distinct subtypes of primary Sjögren's syndrome

scientific article published on 21 August 2020

Genetic associations to germinal centre formation in primary Sjogren's syndrome

scientific article published on 20 April 2013

High Ro52 Expression in Spontaneous and UV-Induced Cutaneous Inflammation

scientific article published on 05 February 2009

How immunological profile drives clinical phenotype of primary Sjögren's syndrome at diagnosis: analysis of 10,500 patients (Sjögren Big Data Project)

scientific article published on 01 May 2018

IL-17: a new actor in IFN-driven systemic autoimmune diseases

scientific article published on September 2012

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

scientific article

Identification of discrete epitopes of Ro52p200 and association with fetal cardiac conduction system manifestations in a rodent model.

scientific article

Immunoglobulin variable genes and epitope recognition of human monoclonal anti-Ro 52-kd in primary Sjögren's syndrome

scientific article

Immunological Contribution to the Pathogenesis of Congenital Heart Block

scientific article published on 01 September 2010

Immunopathogenic mechanisms of systemic autoimmune disease

scientific article published on August 2013

In-depth human plasma proteome analysis captures tissue proteins and transfer of protein variants across the placenta

scientific article published on 08 April 2019

Incident cases of primary Sjögren's syndrome during a 5-year period in Stockholm County: a descriptive study of the patients and their characteristics

scientific article published on 15 September 2014

Increased expression of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in skin lesions of patients with lupus erythematosus

article

Increased extracellular levels of the novel proinflammatory cytokine high mobility group box chromosomal protein 1 in minor salivary glands of patients with Sjögren's syndrome

article

Increased frequency of cells secreting interleukin-6 and interleukin-10 in peripheral blood of patients with primary Sjögren's syndrome

scientific article published on 01 May 1999

Increased risk of multiple myeloma in primary Sjögren's syndrome is limited to individuals with Ro/SSA and La/SSB autoantibodies

scientific article published on 06 November 2019

Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.

scientific article published on June 2006

Infections increase the risk of developing Sjögren's syndrome

scientific article published on 17 April 2019

Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big Data Sjögren Project Consortium

scientific article

Innate immunity and interferons in the pathogenesis of Sjögren's syndrome

scientific article published on 15 February 2019

Interferon activation status underlies higher antibody response to viral antigens in patients with systemic lupus erythematosus receiving no or light treatment

scientific article published on 02 October 2020

Interferon beta treatment of multiple sclerosis increases serum interleukin-7.

scientific article published on 12 May 2014

Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies

scientific article published on May 2008

Interferons and innate immune activation in autoimmune congenital heart block

scientific article published on 14 November 2020

Isotype distribution of anti-Ro/SS-A and anti-La/SS-B antibodies in plasma and saliva of patients with Sjögren's syndrome

scientific article published on 01 January 2000

Killers come to the rescue

scientific article published on 01 December 2002

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome

scientific article published on 21 April 2016

Late development of complete atrioventricular block may be immune mediated and congenital in origin

scientific article published on 30 December 2013

Learning from similarities between vaccine responses and SLE

scientific article published on 17 April 2020

Letter to the Editor in response to the article "Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: a review of published literature and registered clinical trials." by Gleicher N, Elkayam U, A

scientific article published on 2 September 2013

Local production of Ro/SSA and La/SSB autoantibodies in the target organ coincides with high levels of circulating antibodies in sera of patients with Sjögren's syndrome

scientific article published on 01 January 2003

Long-term follow-up in primary Sjögren's syndrome reveals differences in clinical presentation between female and male patients

scientific article published on 08 August 2017

Long-term growth of children with autoantibody-mediated congenital heart block

scientific article published on 22 April 2013

Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

scientific article published on 27 July 2009

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block

scientific article published on 9 August 2010

Mechanisms in fetal bradyarrhythmia: 65 cases in a single center analyzed by Doppler flow echocardiographic techniques

scientific article published on 01 February 2011

Minor salivary gland immunohistology in the diagnosis of primary Sjögren's syndrome.

scientific article published on 12 September 2008

Molecular mechanisms of congenital heart block

scientific article published on 13 January 2014

Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands

scientific article

NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome

scientific article

Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block

scientific article published on 01 October 2020

Neurodevelopment in children with and without congenital heart block born to anti-Ro/SSA-positive mothers

scientific article published in November 2012

No association of primary Sjögren's syndrome with Fcγ receptor gene variants

scientific article published on 4 April 2013

OP0020 Identification of Multiple Sjögren’s Syndrome Susceptibility Loci

OR.56. The Sjögren's Syndrome Associated Autoantigen Ro52 Is a Ring-Dependent E3 Ligase That Regulates Cell Death

Outcome and growth of infants fetally exposed to heart block-associated maternal anti-Ro52/SSA autoantibodies

scientific article published in April 2008

Outcome in 212 anti-Ro/SSA-positive pregnancies and population-based incidence of congenital heart block.

scientific article

Outcome in young patients with isolated complete atrioventricular block and permanent pacemaker treatment: A nationwide study of 127 patients

scientific article published on 18 June 2015

Pacing therapy in children with isolated complete atrioventricular block: a retrospective study of pacing system survival and pacing-related complications in a national cohort

scientific article published on 01 November 2019

Pacing therapy in children with isolated complete atrioventricular block: a retrospective study of pacing system survival and pacing-related complications in a national cohort-Authors' reply

scientific article published on 01 February 2020

Pathogenesis of the Novel Autoimmune-Associated Long-QT Syndrome

scientific article

Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus

scientific article

Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome

article

Primary Sjögren's syndrome--treatment of fetal incomplete atrioventricular block with dexamethasone

scientific article published on 01 February 2001

Progression to first-degree heart block in preschool children exposed in utero to maternal anti-SSA/Ro52 autoantibodies

scientific article published on 16 January 2012

Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjögren's syndrome

scientific article published on 01 January 2020

Rare X chromosome abnormalities in systemic lupus erythematosus and Sjögren's syndrome

scientific article published on 10 July 2017

Reduced expression of TRIM21/Ro52 predicts poor prognosis in diffuse large B-cell lymphoma patients with and without rheumatic disease

scientific article published on 29 May 2015

Reply

scholarly article by Marie Wahren-Herlenius & Sven-Erik Sonesson published January 2005 in Arthritis and Rheumatism

Response to Letter to the Editor by Bartoloni et al: 'Interplay of anti-SSA/SSB status and hypertension in determining cardiovascular risk in primary Sjögren's syndrome'

scientific article published on 05 November 2019

Ro 52kD autoantibodies are detected in a subset of ANA-negative sera

scientific article published on 01 January 2000

Ro/SS-A- and La/SS-B-reactive B lymphocytes in peripheral blood of patients with Sjögren's syndrome

Ro/SSA and La/SSB specific IgA autoantibodies in serum of patients with Sjögren's syndrome and systemic lupus erythematosus

scientific article published on October 1999

Ro/SSA autoantibodies directly bind cardiomyocytes, disturb calcium homeostasis, and mediate congenital heart block

scientific article

Ro/SSA autoantibody-positive pregnancy: reactions to serial fetal Doppler echocardiographic surveillance

scientific article

Ro52 autoantibody-positive women's experience of being pregnant and giving birth to a child with congenital heart block

scientific article published on 10 December 2011

Ro52, Ro60 and La IgG autoantibody levels and Ro52 IgG subclass profiles longitudinally throughout pregnancy in congenital heart block risk pregnancies

scientific article published in January 2006

Self protection from anti-viral responses--Ro52 promotes degradation of the transcription factor IRF7 downstream of the viral Toll-Like receptors

scientific article

Serial analysis of Ro/SSA and La/SSB antibody levels and correlation with clinical disease activity in patients with systemic lupus erythematosus

scientific article published on 01 January 2002

Serologic follow-up of children born to mothers with Ro/SSA autoantibodies

scientific article published on 01 August 2009

Sex differences in clinical presentation of systemic lupus erythematosus

scientific article published on 16 December 2019

Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms

scientific article published on 25 October 2017

Signs of first-degree heart block occur in one-third of fetuses of pregnant women with anti-SSA/Ro 52-kd antibodies

scientific article published in April 2004

Single-Stranded Oligonucleotide-Mediated Inhibition of Respiratory Syncytial Virus Infection

scientific article published on 08 December 2020

Specificity and effector mechanisms of autoantibodies in congenital heart block

scientific article published on 29 September 2006

Spontaneous rupture of atrioventricular valve tensor apparatus as late manifestation of anti-Ro/SSA antibody-mediated cardiac disease

scientific article published on 19 January 2011

State of the art: Reproduction and pregnancy in rheumatic diseases

scientific article published on 30 December 2014

Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52

scientific article

Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome

scientific article published on 01 February 2006

Structurally derived mutations define congenital heart block-related epitopes within the 200-239 amino acid stretch of the Ro52 protein

scientific article

Systemic manifestations of primary Sjögren's syndrome out of the ESSDAI classification: prevalence and clinical relevance in a large international, multi-ethnic cohort of patients

scientific article published on 01 May 2019

TRIM21 is important in the early phase of inflammation in the imiquimod-induced psoriasis-like skin inflammation mouse model.

scientific article published on 11 December 2016

The Expression of BAFF Is Controlled by IRF Transcription Factors.

scientific article published on 20 November 2015

The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

scientific article

The La protein from human liver cells interacts specifically with the U-rich region in the hepatitis C virus 3' untranslated region.

scientific article published in September 1999

The Sjogren's syndrome-associated autoantigen Ro52 is an E3 ligase that regulates proliferation and cell death

scientific article published on May 2006

The Sjögren's syndrome-associated autoantigen Ro52/TRIM21 modulates follicular B cell homeostasis and immunoglobulin production

scientific article published on 16 October 2018

The autoantigen Ro52 is an E3 ligase resident in the cytoplasm but enters the nucleus upon cellular exposure to nitric oxide

scientific article

The complexity of Sjögren's syndrome: novel aspects on pathogenesis

scientific article

The experiences of pregnancy in women with SSA/Ro52 autoantibodies

scientific article published on 12 October 2010

The fellowship of the RING: the RING-B-box linker region interacts with the RING in TRIM21/Ro52, contains a native autoantigenic epitope in Sjögren syndrome, and is an integral and conserved region in TRIM proteins

scientific article

The immunobiology of Ro52 (TRIM21) in autoimmunity: a critical review

scientific article published on 07 March 2012

The rheumatic disease-associated FAM167A-BLK locus encodes DIORA-1, a novel disordered protein highly expressed in bronchial epithelium and alveolar macrophages

scientific article published on 17 April 2018

Transcription profiling of peripheral B cells in antibody-positive primary Sjögren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature

scientific article published on 01 May 2018

Translocation of the novel cytokine HMGB1 to the cytoplasm and extracellular space coincides with the peak of clinical activity in experimentally UV-induced lesions of cutaneous lupus erythematosus

scientific article published on 01 January 2007

Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero

scientific article published on 01 January 2020

Update on the immunobiology of Sjögren's syndrome

scientific article published on September 2015

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

scientific article published on 6 October 2013

Viral antigens elicit augmented immune responses in primary Sjögren's syndrome

scientific article published on 30 October 2019

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome

scientific article published on 29 December 2015

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