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List of works by Stefania Scala

"CXCR4-CXCL12 and VEGF correlate to uveal melanoma progression".

scientific article published in January 2010

A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

scientific article

A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion

scientific article published on 27 October 2015

A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration

scientific article published on 23 April 2009

A possible predictive marker of progression for hepatocellular carcinoma

scientific article

A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients

scientific article published on 10 January 2014

Accreditation for excellence of cancer research institutes: recommendations from the Italian Network of Comprehensive Cancer Centers

scientific article

Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias

scholarly article

Adjuvant treatment of malignant melanoma: where are we?

scientific article

Alpha 2b interferon (IFN) by intraperitoneal administration via temporary catheter in ovarian cancer. Preliminary data.

scientific article

Bevacizumab increases viral distribution in human anaplastic thyroid carcinoma xenografts and enhances the effects of E1A-defective adenovirus dl922-947.

scientific article

Brain-derived neurotrophic factor protects neuroblastoma cells from vinblastine toxicity

scientific article published in August 1996

CD4(+)CD45RA(+)CXCR4 (+) lymphocytes are inversely associated with progression in stages I-III melanoma patients.

scientific article published on 25 September 2009

COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

scientific article published on 23 February 2017

CXC chemokine receptor 4 is expressed in uveal malignant melanoma and correlates with the epithelioid-mixed cell type

scientific article published on 05 April 2007

CXCL12-binding receptors expression in non-small cell lung cancer relates to tumoral microvascular density and CXCR4 positive circulating tumoral cells in lung draining venous blood

scientific article published on 12 December 2011

CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells

scientific article

CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not

scientific article published on 3 November 2014

CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis.

scientific article published on 17 March 2016

CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR.

scientific article published on 26 February 2016

Cell surface expression of major histocompatibility class I antigens is modulated by P-glycoprotein transporter

scientific article published on March 1995

Cellular and biophysical evidence for interactions between adenosine triphosphate and P-glycoprotein substrates: functional implications for adenosine triphosphate/drug cotransport in P-glycoprotein overexpressing tumor cells and in P-glycoprotein l

scientific article published in January 2001

Cetuximab-dependent ADCC in cancer: dream or reality?

scientific article published on 25 June 2010

Chemoresistance in the clinic: overview 1994.

scientific article published on December 1994

Coexpression of TGF alpha, epidermal growth factor receptor, and P-glycoprotein in normal and benign diseased breast tissues

scientific article published on 01 June 1995

Concomitant CXCR4 and CXCR7 Expression Predicts Poor Prognosis in Renal Cancer

scientific article published on 01 November 2010

Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4.

scientific article

Cystic Fibrosis Transmembrane Conductance Regulator and Adenosine Triphosphate

scientific article published on 01 February 1997

Detection, monitoring, and management of trastuzumab-induced left ventricular dysfunction: an actual challenge.

scientific article published on 04 January 2012

Diabetes and Body Mass Index Are Associated with Neuropathy and Prognosis in Colon Cancer Patients Treated with Capecitabine and Oxaliplatin Adjuvant Chemotherapy

scientific article published on 6 January 2016

Differential role of CD133 and CXCR4 in renal cell carcinoma

scientific article published on November 2010

Effect of thymic extract 'thymostimulin' on the incidence of infections and myelotoxicity during adjuvant chemotherapy for breast cancer.

scientific article

Engineering of thermoresponsive gels as a fake metastatic niche

scientific article published in July 2018

Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach.

scientific article published on 27 April 2017

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis.

scientific article published on 03 August 2017

Everolimus and pancreatic neuroendocrine tumors (PNETs): Activity, resistance and how to overcome it.

scientific article published on 27 June 2015

Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer

scientific article published on 21 October 2020

Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists

scientific article

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma

scientific article published on 01 March 2005

Fc gamma receptor IIIa polymorphisms in advanced colorectal cancer patients correlated with response to anti-EGFR antibodies and clinical outcome.

scientific article published on 21 November 2012

HCV-related hepatocellular carcinoma: From chronic inflammation to cancer

scientific article

HMGI-C gene expression is not required for in vivo thyroid cell transformation

scientific article published in February 2001

High CXCR4 expression correlates with sunitinib poor response in metastatic renal cancer.

scientific article

Histomorphologic parameters and CXCR4 mRNA and protein expression in sentinel node melanoma metastasis are correlated to clinical outcome

scientific article published on 20 March 2010

Human melanoma metastases express functional CXCR4.

scientific article published on April 2006

IRF-8 controls melanoma progression by regulating the cross talk between cancer and immune cells within the tumor microenvironment.

scientific article published on December 2012

Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer

scientific article

In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies

scientific article published on 01 March 2022

Increase in AP-1 activity is a general event in thyroid cell transformation in vitro and in vivo

scientific article published in July 1998

Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells

scientific article

Inhibition of stromal CXCR4 impairs development of lung metastases.

scientific article

Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells

scientific article published on 11 December 2004

Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation.

scientific article published on 26 July 2009

Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation.

scientific article

Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles

scientific article published on 01 November 2015

Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells

scientific article published on 9 March 2018

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Modulation of chemosensitivity by alpha interferon in multiple myeloma and non-Hodgkin's lymphoma

scientific article published on 01 July 1996

Molecular Pathways: Targeting the CXCR4-CXCL12 Axis--Untapped Potential in the Tumor Microenvironment

scientific article published on 21 July 2015

Natural killer cells activity in a metastatic colorectal cancer patient with complete and long lasting response to therapy.

scientific article published in November 2017

New CXCR4 Antagonist Peptide R (Pep R) Improves Standard Therapy in Colorectal Cancer

scientific article published on 18 July 2020

New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM

scientific article published on 03 April 2020

Novel mutation of the PTEN gene in an Italian Cowden's disease kindred

article

ONYX-015, an E1B gene-defective adenovirus, induces cell death in human anaplastic thyroid carcinoma cell lines

article

Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients

scientific article published on May 2006

P01.16MICROGLIA/MACROPHAGES AS CELLULAR TARGET OF NOVEL CXCR4 ANTAGONIST IN A GLIOMA MODEL.

scientific article published in September 2014

Pegylated arginine deiminase treatment of patients with metastatic melanoma: results from phase I and II studies

scientific article published in October 2005

Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies

scientific article published on 28 January 2014

Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial

scientific article

Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases

scientific article

Prediction of response to anti-EGFR antibodies in metastatic colorectal cancer: looking beyond EGFR inhibition

scientific article published on January 2012

Prognostic role of the CDNK1B V109G polymorphism in multiple endocrine neoplasia type 1.

scientific article published on 30 March 2015

Prognostic value of serum VEGF in melanoma patients: a pilot study

scientific article published on 01 November 2004

Prospective Evaluation of Cetuximab-Mediated Antibody-Dependent Cell Cytotoxicity in Metastatic Colorectal Cancer Patients Predicts Treatment Efficacy

scientific article published on 27 January 2016

Prostate cancer detection in the "grey area" of prostate-specific antigen below 10 ng/ml: head-to-head comparison of the updated PCPT calculator and Chun's nomogram, two risk estimators incorporating prostate cancer antigen 3.

scientific article

RETRACTED: Critical role of the HMGI(Y) proteins in adipocytic cell growth and differentiation

retracted scientific article

Radiation therapy following surgery for localized breast cancer: outcome prediction by classical prognostic factors and approximated genetic subtypes

scientific article published on 26 September 2012

Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression

scientific article published on June 1997

Regulatory T cells, interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), CXCL10, CXCL11, epidermal growth factor (EGF) and hepatocyte growth factor (HGF) as surrogate markers of host immunity in patients with renal cell carcinoma

scientific article published on 15 March 2013

Resistance to paclitaxel mediated by P-glycoprotein can be modulated by changes in the schedule of administration

scientific article published on January 1997

Reversal of Multidrug Resistance

scientific article published on 01 January 1994

Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells

scientific article published on September 1991

Reversal of multidrug resistance.

scientific article

Serum cytokine levels in patients with hepatocellular carcinoma

scientific article

Soluble interleukin-2 receptor in stage I–III melanoma

scientific article published on 01 February 2006

Structure-Activity Relationships and Biological Characterization of a Novel, Potent, and Serum Stable C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonist

scientific article published on 10 November 2017

Study of Ras Mutations' Prognostic Value in Metastatic Colorectal Cancer: STORIA Analysis

scientific article published on 16 July 2020

Targeting CXCR4 by a selective peptide antagonist modulates tumor microenvironment and microglia reactivity in a human glioblastoma model

scientific article published on 25 March 2016

Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer.

scientific article published on 19 August 2017

Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment ⬇️

scientific article published on November 3, 2010

Temozolomide and cisplatin in avdanced malignant melanoma.

scientific article published in March 2005

The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis, and binding studies

scientific article published on 23 May 2012

Tissue Micro Arrays for immunohistochemical detection of inflammatory infiltrates in renal cell carcinoma

scientific article published on 15 March 2014

Tissue micro arrays for immunohistochemical detection of inflammatory infiltrates in renal cell carcinoma

scientific article published on 15 April 2014

Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts

scientific article published on July 1998

Tumour biomarkers: homeostasis as a novel prognostic indicator

scientific article

Variability in Immunohistochemical Detection of Programmed Death Ligand 1 (PD-L1) in Cancer Tissue Types.

scientific article published on 21 May 2016

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