List of works by Steven Goossens

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

scientific article published in Nature

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

scientific article published on 9 October 2014

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

scientific article published on 23 September 2020

Alpha-T-catenin (CTNNA3) displays tumour specific monoallelic expression in urothelial carcinoma of the bladder

scientific article published on June 2007

Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease

scientific article published on January 2004

Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity

scientific article

Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy

scientific article

Cadherin-mediated cell-cell adhesion in the testis.

scientific article

Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus.

scientific article published in May 2016

Controlling pre-leukemic thymocyte self-renewal

scientific article published on 18 December 2014

Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.

scientific article

Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells

scientific article published in December 2013

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

scientific article published on 11 March 2009

GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.

scientific article

Immunohistological Description of Nongestational Ovarian Choriocarcinoma in Two Female Mice With Conditional Loss of Trp53 Driven by the Tie2 Promoter

scientific article published on 24 September 2014

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

scientific article

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

scientific article published on 30 October 2017

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

scientific article published on 11 March 2016

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice.

scientific article published on 11 March 2014

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

scientific article

MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia

scientific article

Novel biological insights in T-cell acute lymphoblastic leukemia

scientific article published on 26 June 2015

Novel oncogenic noncoding mutations in T-ALL.

scientific article published in June 2017

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

scientific article published on 22 July 2019

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

scientific article published on 9 January 2017

Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia.

scientific article

Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation

scientific article

Strategies to rescue the consequences of inducible arginase-1 deficiency in mice

scientific article

Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.

scientific article published on 11 January 2017

Targeting cytokine and therapy induced PIM1 activation in T-cell acute lymphoblastic leukemia and lymphoma

scientific article published on 13 February 2020

Targeting steroid resistance in T-cell acute lymphoblastic leukemia

scientific article published on 19 July 2019

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

scientific article

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization

scientific article published on 25 February 2011

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

scientific article published on 05 June 2020

The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling

scientific article published on 28 September 2016

The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation

scientific article published on 7 February 2013

The p53 family and VEGF regulation: "It's complicated".

scientific article published on 11 April 2013

Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice

scientific article

Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection

scientific article

Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function

scientific article published on 21 December 2006

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

scientific article published on 17 September 2018

Vegf regulates embryonic erythroid development through Gata1 modulation

scientific article published on 16 June 2010

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

scientific article published on 24 January 2019

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

scientific article

ZEB2 in T-cells and T-ALL

scientific article published on 27 July 2019

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

scientific article published on 16 November 2018

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

scientific article published on 27 February 2014

Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells

scientific article

alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion

scientific article

p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification

scientific article

p53 promotes VEGF expression and angiogenesis in the absence of an intact p21-Rb pathway.

scientific article published on March 2013

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