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List of works by José Luís Martínez

A function of SmeDEF, the major quinolone resistance determinant of Stenotrophomonas maltophilia, is the colonization of plant roots

scientific article published on August 2014

A molecular biological protocol to distinguish potentially human pathogenic Stenotrophomonas maltophilia from plant-associated Stenotrophomonas rhizophila

scientific article published in November 2005

A novel resistance mechanism to triclosan that suggests horizontal gene transfer and demonstrates a potential selective pressure for reduced biocide susceptibility in clinical strains of Staphylococcus aureus

scientific article published on 11 July 2012

Acquisition of antibiotic resistance plasmids in vivo by extraintestinal Salmonella spp.

scientific article published in September 1987

Aerobactin production and plasmid distribution in Escherichia coli clinical isolates.

scientific article

Aerobactin-producing multi-resistance plasmids

scientific article

Antibiotic inactivating enzymes from a clinical isolate of Agrobacterium radiobacter

scientific article

Antibiotic resistance: Time of synthesis in a post-genomic age

publication published on 21 May 2021

Antibiotic-resistant Klebsiella pneumoniae and Escherichia coli high-risk clones and an IncFII(k) mosaic plasmid hosting Tn1 (blaTEM-4) in isolates from 1990 to 2004.

scientific article

Antibiotics and antibiotic resistance genes in natural environments

scientific article published on 01 July 2008

Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics

scientific article published on 30 September 2020

Antimicrobial resistance: A multifaceted problem with multipronged solutions

scientific article published on 01 November 2019

Are nonlethal targets useful for developing novel antimicrobials? ⬇️

scientific article published on June 1, 2011

Bacterial Multidrug Efflux Pumps: Much More Than Antibiotic Resistance Determinants

scientific article

Bacterial lineages putatively associated with the dissemination of antibiotic resistance genes in a full-scale urban wastewater treatment plant

scientific article published on 05 June 2018

Bacterial pathogens: from natural ecosystems to human hosts ⬇️

scientific article published on August 1, 2012

Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics.

scientific article published on 09 August 2011

Bleomycin increases amikacin and streptomycin resistance in Escherichia coli harboring transposon Tn5 ⬇️

scientific article published on September 1, 1993

Bleomycin-kanamycin resistance as a marker of the presence of transposon Tn5 in clinical strains of Escherichia coli.

scientific article published in November 1989

Bottlenecks in the transferability of antibiotic resistance from natural ecosystems to human bacterial pathogens.

scientific article published on January 2011

Characterization of a novel Zn²⁺-dependent intrinsic imipenemase from Pseudomonas aeruginosa

scientific journal article

Characterization of the polymyxin B resistome of Pseudomonas aeruginosa.

scientific article

Chronic Pseudomonas aeruginosa infection in chronic obstructive pulmonary disease

scientific article published on 01 December 2008

Clinical impact of the over-expression of efflux pump in nonfermentative Gram-negative bacilli, development of efflux pump inhibitors

scientific article published on September 2008

Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia

scientific article

Cloning and characterization of SmeT, a repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF.

scientific article published on November 2002

Cloning of the determinants for microcin D93 production and analysis of three different D-type microcin plasmids

scientific article published on 01 May 1990

Defining and combating antibiotic resistance from One Health and Global Health perspectives

scientific article published on 22 August 2019

Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains.

scientific article

Differential epigenetic compatibility of qnr antibiotic resistance determinants with the chromosome of Escherichia coli.

scientific article

Differential interactions within the Caenorhabditis elegans-Pseudomonas aeruginosa pathogenesis model

scientific article published on 01 December 2003

Dissemination of Novel Antimicrobial Resistance Mechanisms through the Insertion Sequence Mediated Spread of Metabolic Genes

scientific article published on 28 June 2016

Do bacteria have sex?

scientific article published in Nature

Double-Face Meets the Bacterial World: The Opportunistic Pathogen Stenotrophomonas maltophilia

scientific article

Draft Genome Sequences of Two Ralstonia pickettii Strains with Different Aminoglycoside Resistance Phenotypes.

scientific article published on 10 November 2016

Ecology and Evolution of Chromosomal Gene Transfer between Environmental Microorganisms and Pathogens.

scientific article published in January 2018

Ecology and evolution of antibiotic resistance.

scientific article published on 28 July 2009

Editorial: A Multidisciplinary Look at Stenotrophomonas maltophilia: An Emerging Multi-Drug-Resistant Global Opportunistic Pathogen

scientific article published on 31 August 2017

Effect of antibiotics on bacterial populations: a multi-hierachical selection process.

scientific article published on 17 January 2017

Emergence and spread of antibiotic resistance: setting a parameter space.

scientific article

Environmental and clinical isolates of Pseudomonas aeruginosa show pathogenic and biodegradative properties irrespective of their origin

scientific article

Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms

scientific article published on 18 March 2020

Epidemiology of antibiotic-inactivating enzymes and DNA probes: the problem of quantity

scientific article published in September 1990

Evaluation of epidemiological cut-off values indicates that biocide resistant subpopulations are uncommon in natural isolates of clinically-relevant microorganisms.

scientific article published on 23 January 2014

Evolution of Habitat-Dependent Antibiotic Resistance in Pseudomonas aeruginosa

scientific article published in 2022

Evolutionary Pathways and Trajectories in Antibiotic Resistance

scientific article published in 2021

Experimental validation of Haldane's hypothesis on the role of infection as an evolutionary force for Metazoans

scholarly article

Expression of multidrug efflux pump SmeDEF by clinical isolates of Stenotrophomonas maltophilia

scientific article

Factors determining resistance to beta-lactam combined with beta-lactamase inhibitors in Escherichia coli

scientific article published in May 1991

Fitness costs associated with the acquisition of antibiotic resistance.

scientific article published on February 2017

Fitness of in vitro selected Pseudomonas aeruginosa nalB and nfxB multidrug resistant mutants

scientific article published in November 2002

Fosfomycin and rifampin disk diffusion tests for detection of Escherichia coli mutator strains

scientific article

Friends or foes: can we make a distinction between beneficial and harmful strains of the Stenotrophomonas maltophilia complex?

scientific article published on 31 March 2015

General principles of antibiotic resistance in bacteria

scientific article published on March 2014

Genome-wide analysis shows that RNase G plays a global role in the stability of mRNAs in Stenotrophomonas maltophilia

scientific article published on 22 November 2017

Genomic and metagenomic technologies to explore the antibiotic resistance mobilome

scientific article published on 10 November 2016

Growth of Escherichia coli in acetate as a sole carbon source is inhibited by ankyrin-like repeats present in the 2',5'-linked oligoadenylate-dependent human RNase L enzyme.

scientific article published in April 1997

H-NS and RpoS regulate emergence of Lac Ara+ mutants of Escherichia coli MCS2.

scientific article published on July 1997

High-level quinolone resistance is associated with the overexpression of smeVWX in Stenotrophomonas maltophilia clinical isolates

scientific article published on 23 January 2015

Hns mutant unveils the presence of a latent haemolytic activity in Escherichia coli K-12.

scientific article

In vitro plasmid-encoded resistance to quinolones.

scientific article published in September 1997

In-depth resistome analysis by targeted metagenomics.

scientific article

Increased mutation frequencies in Escherichia coli isolates harboring extended-spectrum beta-lactamases

scientific article published on November 2005

Interkingdom signaling and its consequences for human health

scientific article published on 6 February 2014

Interplay between intrinsic and acquired resistance to quinolones in Stenotrophomonas maltophilia

scientific article published on 04 March 2014

Interventions on Metabolism: Making Antibiotic-Susceptible Bacteria.

scientific article published on 28 November 2017

Involvement of the RND efflux pump transporter SmeH in the acquisition of resistance to ceftazidime in Stenotrophomonas maltophilia

scientific article published on 20 March 2019

Lack of evidence for reduced fitness of clinical Staphylococcus aureus isolates with reduced susceptibility to triclosan

scientific article published on November 2012

Macrolide resistance genes in Enterococcus spp

scientific article

Mechanisms and phenotypic consequences of acquisition of tigecycline resistance by Stenotrophomonas maltophilia

scientific article published on 01 November 2019

Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps.

scientific article published on 25 July 2017

Metabolic compensation of fitness costs associated with overexpression of the multidrug efflux pump MexEF-OprN in Pseudomonas aeruginosa.

scientific article

Metabolic regulation of antibiotic resistance.

scientific article published on 28 June 2011

Metagenomic analysis of an urban resistome before and after wastewater treatment

scientific article published on 18 May 2020

Metagenomics Analysis Reveals an Extraordinary Inner Bacterial Diversity in Anisakids (Nematoda: Anisakidae) L3 Larvae

scientific article published in 2021

Metagenomics and antibiotics ⬇️

scientific article published on July 1, 2012

Metal Accumulation and Vanadium-Induced Multidrug Resistance by Environmental Isolates of Escherichia hermannii and Enterobacter cloacae ⬇️

scientific article published on November 1, 1998

Methods for Measuring the Production of Quorum Sensing Signal Molecules.

scientific article published in January 2018

Microcin 15n: a second antibiotic from Escherichia coli LP15

scientific article published on 01 March 1983

Microcin-mediated Interactions Between Klebsiella pneumoniae and Escherichia coliStrains ⬇️

scientific article published on 01 February 1984

Multidrug Efflux Pumps at the Crossroad between Antibiotic Resistance and Bacterial Virulence

scientific article

Multidrug efflux pumps as main players in intrinsic and acquired resistance to antimicrobials.

scientific article published on 30 June 2016

Multilevel selection of bcrABDR-mediated bacitracin resistance in Enterococcus faecalis from chicken farms

scientific article published on 12 October 2016

Multiple adaptive routes of Salmonella enterica Typhimurium to biocide and antibiotic exposure.

scientific article

Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.

scientific article

Mutation rate is reduced by increased dosage of mutL gene in Escherichia coli K-12.

scientific article published on 7 September 2007

Mutation-Driven Evolution of Pseudomonas aeruginosa in the Presence of either Ceftazidime or Ceftazidime-Avibactam

scientific article published on 24 September 2018

Mutational Evolution of Resistance to Ribosome-Targeting Antibiotics

scientific article published on 18 October 2018

Natural Antibiotic Resistance and Contamination by Antibiotic Resistance Determinants: The Two Ages in the Evolution of Resistance to Antimicrobials ⬇️

scientific article published on January 13, 2012

Non-canonical mechanisms of antibiotic resistance.

scientific article published on December 1994

Normal mutation rate variants arise in a Mutator (Mut S) Escherichia coli population.

scientific article

Novel Inducers of the Expression of Multidrug Efflux Pumps That Trigger Pseudomonas aeruginosa Transient Antibiotic Resistance

scientific article published on 22 October 2019

Oleoylanilide, a possible causative agent of toxic oil syndrome, interferes with the cytoskeleton in a neuronal cell line.

scientific article published on March 1997

Overexpression of the efflux pumps SmeVWX and SmeDEF is a major cause of resistance to cotrimoxazole in Stenotrophomonas maltophilia.

scientific article

Overexpression of the multidrug efflux pump SmeDEF impairs Stenotrophomonas maltophilia physiology.

scientific article

Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa

scientific article published on February 2005

Overproduction of the multidrug efflux pump MexEF-OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in bacterial regulatory networks.

scientific article published on 15 March 2012

Phenotypic Resistance to Antibiotics.

scientific article published on 18 April 2013

Polymorphic mutation frequencies of clinical and environmental Stenotrophomonas maltophilia populations.

scientific article published on 22 January 2010

Polymorphic variation in susceptibility and metabolism of triclosan-resistant mutants of Escherichia coli and Klebsiella pneumoniae clinical strains obtained after exposure to biocides and antibiotics

scientific article published on 30 March 2015

Predictive Studies Suggest that the Risk for the Selection of Antibiotic Resistance by Biocides Is Likely Low in Stenotrophomonas maltophilia

scientific article

Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants

scientific article

Prioritizing risks of antibiotic resistance genes in all metagenomes

scientific article published on 27 April 2015

Quantitative proteomics unravels that the post-transcriptional regulator Crc modulates the generation of vesicles and secreted virulence determinants of Pseudomonas aeruginosa

scientific article published on 21 June 2015

Quinolone resistance by mutations in chromosomal gyrase genes. Just the tip of the iceberg?

scientific article

Quinolone resistance: much more than predicted.

scientific article

RND multidrug efflux pumps: what are they good for?

scientific article published on 5 February 2013

Rapid and robust evolution of collateral sensitivity in Pseudomonas aeruginosa antibiotic-resistant mutants

scientific article published on 05 August 2020

Recent advances in the potential interconnection between antimicrobial resistance to biocides and antibiotics.

scientific article published in April 2013

Regulation of Smqnr expression by SmqnrR is strain-specific in Stenotrophomonas maltophilia

scientific article published on 14 July 2015

Regulatory regions of smeDEF in Stenotrophomonas maltophilia strains expressing different amounts of the multidrug efflux pump SmeDEF.

scientific article

Sewage dilution and loss of antibiotic resistance and virulence determinants in E. coli.

scientific article

Shigella sonnei bacteremia in an elderly diabetic patient

scientific article published in June 1988

Short-sighted evolution of bacterial opportunistic pathogens with an environmental origin

scientific article

SmQnr contributes to intrinsic resistance to quinolones in Stenotrophomonas maltophilia.

scientific article published on 19 October 2009

Small plasmids are involved in amoxicillin-clavulanate resistance in Escherichia coli

scientific article

Stenotrophomonas maltophilia D457R contains a cluster of genes from gram-positive bacteria involved in antibiotic and heavy metal resistance

scientific article published on July 2000

Structural and functional analysis of SmeT, the repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF

scientific article

Structure of Pseudomonas aeruginosa populations analyzed by single nucleotide polymorphism and pulsed-field gel electrophoresis genotyping. ⬇️

scientific article

Synergistic effect of dosage and bacterial inoculum in TEM-1 mediated antibiotic resistance

scientific article published on 01 December 1988

Tackling antibiotic resistance: the environmental framework

scientific article

The Binding of Triclosan to SmeT, the Repressor of the Multidrug Efflux Pump SmeDEF, Induces Antibiotic Resistance in Stenotrophomonas maltophilia

scientific article

The DSF quorum sensing system controls the positive influence of Stenotrophomonas maltophilia on plants.

scientific article published on 18 July 2013

The Inactivation of Enzymes Belonging to the Central Carbon Metabolism Is a Novel Mechanism of Developing Antibiotic Resistance

scientific article published on 02 June 2020

The Inactivation of intrinsic antibiotic resistance determinants widens the mutant selection window for quinolones in Stenotrophomonas maltophilia.

scientific article published on 24 September 2012

The Plasmidome of Firmicutes: Impact on the Emergence and the Spread of Resistance to Antimicrobials.

scientific article published on April 2015

The analysis of the antibiotic resistome offers new opportunities for therapeutic intervention

scientific article published on 15 June 2016

The antibiotic resistome: challenge and opportunity for therapeutic intervention.

scientific article published on March 2012

The biocide triclosan selects Stenotrophomonas maltophilia mutants that overproduce the SmeDEF multidrug efflux pump

scientific article published on February 2005

The development of a new parameter for tracking post-transcriptional regulation allows the detailed map of the Pseudomonas aeruginosa Crc regulon

scientific article published in Scientific Reports

The development of efflux pump inhibitors to treat Gram-negative infections

scientific article published on 10 September 2018

The efflux pump SmeDEF contributes to trimethoprim-sulfamethoxazole resistance in Stenotrophomonas maltophilia

scientific article

The efflux pump inhibitor Phe-Arg-beta-naphthylamide does not abolish the activity of the Stenotrophomonas maltophilia SmeDEF multidrug efflux pump

scientific article published on 13 March 2003

The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies

scientific article published on 3 August 2016

The global regulator Crc modulates metabolism, susceptibility to antibiotics and virulence in Pseudomonas aeruginosa

scientific journal article

The global regulator Crc orchestrates the metabolic robustness underlying oxidative stress resistance in Pseudomonas aeruginosa

scientific article published on 16 December 2018

The impaired quorum sensing response of MexAB-OprM efflux pump overexpressing mutants is not due to non-physiological efflux of 3-oxo-C12-HSL

scientific article published on 26 July 2020

The inactivation of RNase G reduces the Stenotrophomonas maltophilia susceptibility to quinolones by triggering the heat shock response

scientific article published on 19 October 2015

The intrinsic resistome of Klebsiella pneumoniae

scientific article published on 17 September 2018

The intrinsic resistome of Pseudomonas aeruginosa to β-lactams.

scientific article

The intrinsic resistome of bacterial pathogens ⬇️

scientific article published on April 30, 2013

The neglected intrinsic resistome of bacterial pathogens

scientific article

The organization of intercistronic regions of the aerobactin operon of pColV-K30 may account for the differential expression of the iucABCD iutA genes

scientific article published on April 1994

The role of natural environments in the evolution of resistance traits in pathogenic bacteria

scientific article published on 8 April 2009

The use of machine learning methodologies to analyse antibiotic and biocide susceptibility in Staphylococcus aureus.

scientific article

Use of phenotype microarrays to study the effect of acquisition of resistance to antimicrobials in bacterial physiology.

scientific article published on 19 April 2016

Vitamin K3 Induces the Expression of the Stenotrophomonas maltophilia SmeVWX Multidrug Efflux Pump.

scientific article published on 21 February 2017

What is a resistance gene? Ranking risk in resistomes

scientific article published on 15 December 2014

Whole-genome sequence of Stenotrophomonas maltophilia D457, a clinical isolate and a model strain.

scientific article published on July 2012

[Grampositive pathogen clonal diversification and evolution: new perspectives in the XXI century]

scientific article published on 22 June 2010

pH modulation of aminoglycoside resistance in Staphylococcus epidermidis harbouring 6'-N-aminoglycoside acetyltransferase

scientific article

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