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List of works by Calman A MacLennan

A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014)

scientific article

A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalized modules for membrane antigens (GMMA).

scientific article published on 3 April 2014

A scalable method for O-antigen purification applied to various Salmonella serovars.

scientific article

Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody.

scientific article published on 7 January 2011

Acetylcholine receptor expression in human extraocular muscles and their susceptibility to myasthenia gravis

Affordable pediatric CD4 counting by flow cytometry in Malawi

scientific article published on January 2008

Age- and sex-related changes in hematological parameters in healthy Malawians

scientific article published on 28 August 2017

An O antigen capsule modulates bacterial pathogenesis in Shigella sonnei

scientific article

Anti-interleukin-12 antibody treatment for Crohn disease: potential risk of invasive disease due to mycobacteria and salmonellae infection

scientific article published in May 2005

Antibodies affecting ion channel function in acquired neuromyotonia, in seropositive and seronegative myasthenia gravis, and in antibody-mediated arthrogryposis multiplex congenita

scientific article published on May 1998

Antibodies and protection against invasive salmonella disease

scientific article published on 22 December 2014

Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway

scientific article published on 27 May 2019

Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection

scientific article

Brief Report: Immunization of HIV-Infected Adults in the UK With Haemophilus influenzae b/Meningococcal C Glycoconjugate and Pneumococcal Polysaccharide Vaccines

scientific article

Can we defeat meningococcal disease in low and middle income countries?

scientific article published on May 2012

Cerebrospinal Fluid Studies in Kenyan Children with Severe Falciparum Malaria

scientific article

Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium.

scientific article

Characterization of vaccine antigens of meningococcal serogroup W isolates from Ghana and Burkina Faso from 2003 to 2009.

scientific article

Click Chemistry Applied to the Synthesis of Salmonella Typhimurium O-Antigen Glycoconjugate Vaccine on Solid Phase with Sugar Recycling

scientific article

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal

article published in the Proceedings of the National Academy of Sciences of the United States of America

Comparing the roles of antibodies to nontyphoidal Salmonella enterica in high- and low-income countries and implications for vaccine development

scientific article published on 31 July 2013

Comparison of colorimetric assays with quantitative amino acid analysis for protein quantification of Generalized Modules for Membrane Antigens (GMMA).

scientific article published in January 2015

Consensus Report on Shigella Controlled Human Infection Model: Clinical Endpoints

scientific article published on 01 December 2019

Consensus Report on Shigella Controlled Human Infection Model: Conduct of Studies

scientific article published on 01 December 2019

Consensus Report on Shigella Controlled Human Infection Model: Immunological Assays

scientific article published on 01 December 2019

Consensus Report on Shigella Controlled Human Infection Model: Introduction and Overview

scientific article published on 01 December 2019

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1.

scientific article

Control lymphocyte subsets: can one country's values serve for another's?

scientific article

Cross-sectional study of IgG antibody levels to invasive nontyphoidal Salmonella LPS O-antigen with age in Uganda

scientific article published on 26 June 2019

Cytokine Profiles during Invasive Nontyphoidal Salmonella Disease Predict Outcome in African Children

scientific article published on 11 May 2016

Cytokine Profiles in Malawian Children Presenting with Uncomplicated Malaria, Severe Malarial Anemia, and Cerebral Malaria.

scientific article published on 25 January 2017

Determinant spreading and immune responses to acetylcholine receptors in myasthenia gravis

article

Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X.

scientific article

Diagnostic accuracy and clinical utility of a simplified low cost method of counting CD4 cells with flow cytometry in Malawi: diagnostic accuracy study

scientific article published on 17 July 2007

Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen

scientific article published on 7 January 2016

Differential timing of antibody-mediated phagocytosis and cell-free killing of invasive African Salmonella allows immune evasion.

scientific article published on 20 January 2014

Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published on 22 August 2016

Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults

scientific article published on April 2010

Early interferon-γ production in human lymphocyte subsets in response to nontyphoidal Salmonella demonstrates inherent capacity in innate cells

scientific article (publication date: 27 October 2010)

Emergence of host-adapted Salmonella Enteritidis through rapid evolution in an immunocompromised host

scientific article published on 25 January 2016

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

scientific article published on 9 November 2009

Erratum: Distinct Salmonella Enteritidis lineages associated with enterocolitis in high-income settings and invasive disease in low-income settings

scientific article published in March 2017

Expression of muscle proteins in thymomas of patients with myasthenia gravis.

scientific article published in May 1998

Failure to clear persistent vaccine-derived neurovirulent poliovirus infection in an immunodeficient man.

scientific article

Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

scientific article

Genetic susceptibility to invasive Salmonella disease

scientific article published on June 2015

Genetic variants associated with non-typhoidal Salmonella bacteraemia in African children.

scientific article published on February 2015

Genomic characterization of novel Neisseria species

scientific article published on 24 September 2019

Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi

scientific article published on 27 July 2012

Gonococcal vaccines: Public health value and preferred product characteristics; report of a WHO global stakeholder consultation, January 2019

scientific article published on 28 April 2020

HIV infection compounds the lymphopenia associated with cerebral malaria in Malawian children

article

Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway

scientific article

Host defense against malaria favors Salmonella ⬇️

scientific article published on January 6, 2012

How can controlled human infection models accelerate clinical development and policy pathways for vaccines against Shigella?

scientific article published on 01 August 2019

Human nicotinic acetylcholine receptor alpha-subunit isoforms: origins and expression

scientific article published on November 1993

Identification of a common immune signature in murine and human systemic Salmonellosis

scientific article

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates

scientific article published on 6 March 2018

IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium.

scientific article published on 10 November 2017

Immunogenicity of a Bivalent Adjuvanted Glycoconjugate Vaccine against Salmonella Typhimurium and Salmonella Enteritidis

scientific article published on 27 February 2017

Impact of conjugation chemistry on the immunogenicity of S. Typhimurium conjugate vaccines

scientific article published on 3 September 2014

Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans

scientific article

Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing

scientific article published on 11 August 2014

Interleukin (IL)-12 and IL-23 are key cytokines for immunity against Salmonella in humans

scientific article published on 7 October 2004

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

scientific article

Invasive African Salmonella Typhimurium induces bactericidal antibodies against O-antigens

scientific article

Invasive African nontyphoidal Salmonella requires high levels of complement for cell-free antibody-dependent killing

scientific article published on 22 October 2012

Invasive Nontyphoidal Salmonella Disease in Africa

scientific article published on 01 January 2019

Invasive nontyphoidal Salmonella disease in Africa: current status

scientific article published in May 2013

Leukocyte counts and lymphocyte subsets in relation to pregnancy and HIV infection in Malawian women

scientific article published on 6 April 2017

Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria

scientific article published on 18 November 2015

Lymphocyte subsets in healthy Malawians: implications for immunologic assessment of HIV infection in Africa

scientific article

Measurement of antibodies to pneumococcal, meningococcal and haemophilus polysaccharides, and tetanus and diphtheria toxoids using a 19-plexed assay

scientific article published on 24 January 2012

Meningococcal X polysaccharide quantification by high-performance anion-exchange chromatography using synthetic N-acetylglucosamine-4-phosphate as standard

scientific article published on 09 August 2013

Modulation of endotoxicity of Shigella generalized modules for membrane antigens (GMMA) by genetic lipid A modifications: relative activation of TLR4 and TLR2 pathways in different mutants

scientific article

Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa

scientific article published on 22 September 2016

Monoclonal Antibodies of a Diverse Isotype Induced by an O-Antigen Glycoconjugate Vaccine Mediate In Vitro and In Vivo Killing of African Invasive Nontyphoidal Salmonella

scientific article

Monocyte activation and cytokine production in Malawian children presenting with P. falciparum malaria

scientific article published on 30 March 2016

Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016

scholarly article by Ibrahim A Khalil et al published 25 September 2018 in Lancet Infectious Diseases

Muscle nicotinic acetylcholine receptor mRNA expression in hyperplastic and neoplastic myasthenia gravis thymus.

scientific article published in May 1998

New genomics studies to understand the link between nontyphoidal Salmonella bacteremia and gastroenteritis in Africa

scientific article

Nontyphoidal salmonella disease: Current status of vaccine research and development

scientific article

Out of Africa: links between invasive nontyphoidal Salmonella disease, typhoid fever, and malaria

scientific article published on 13 December 2013

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

scientific article published on 12 February 2020

Outer membrane vesicle vaccines

scientific article published on 09 December 2020

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

scientific article published on 11 May 2015

Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria-possible modulation in vivo by thrombocytopenia

scientific article

Potential neurovirulence of common cold virus

scientific article published in November 2004

Preferential expression of AChR epsilon-subunit in thymomas from patients with myasthenia gravis

scientific article

Presentation of life-threatening invasive nontyphoidal Salmonella disease in Malawian children: A prospective observational study

scientific article published on 7 December 2017

Priorities for research on meningococcal disease and the impact of serogroup A vaccination in the African meningitis belt ⬇️

scientific article published on December 27, 2012

Purification of antibodies to O antigen of Salmonella Typhimurium from human serum by affinity chromatography

scientific article

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313.

scientific article published on 25 April 2019

Relationship between antibody susceptibility and lipopolysaccharide O-antigen characteristics of invasive and gastrointestinal nontyphoidal Salmonellae isolates from Kenya

scientific article

Relative stability of meningococcal serogroup A and X polysaccharides

scientific article published on 22 August 2012

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4. ⬇️

scientific article

Role of sapA and yfgA in Susceptibility to Antibody-Mediated Complement-Dependent Killing and Virulence of Salmonella enterica Serovar Typhimurium.

scientific article

SadA, a trimeric autotransporter from Salmonella enterica serovar Typhimurium, can promote biofilm formation and provides limited protection against infection

scientific article published on 22 August 2011

Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in Malawian children

scientific article published on 16 January 2014

Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine

scientific article published on 08 September 2020

Simplified low-cost production of O-antigen from Salmonella Typhimurium Generalized Modules for Membrane Antigens (GMMA).

scientific article published on 3 February 2015

Status of paratyphoid fever vaccine research and development

scientific article

Strain Selection for Generation of O-Antigen-Based Glycoconjugate Vaccines against Invasive Nontyphoidal Salmonella Disease

scientific article

Structural analysis of O-polysaccharide chains extracted from different Salmonella Typhimurium strains

scientific article published on 11 December 2013

Structural analysis of the O-acetylated O-polysaccharide isolated from Salmonella paratyphi A and used for vaccine preparation

scientific article published on 20 December 2014

Sugar-Protein Connectivity Impacts on the Immunogenicity of Site-Selective Salmonella O-Antigen Glycoconjugate Vaccines

scientific article

T Cell Subset Enumeration and Weekend HIV Clinics: Reliable Performance of CD4 Cell Counts after 3 Days

article

T-Regulatory Cells and Inflammatory and Inhibitory Cytokines in Malawian Children Residing in an Area of High and an Area of Low Malaria Transmission During Acute Uncomplicated Malaria and in Convalescence

scientific article published on 7 January 2015

The Relationship Between Invasive Nontyphoidal Salmonella Disease, Other Bacterial Bloodstream Infections, and Malaria in Sub-Saharan Africa

scientific article published on March 2016

The Severe Typhoid Fever in Africa Program: Study Design and Methodology to Assess Disease Severity, Host Immunity, and Carriage Associated With Invasive Salmonellosis

scientific article published on 01 October 2019

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies

scientific article published on April 2017

The capsular polysaccharide Vi from Salmonella typhi is a B1b antigen

scientific article published on 16 November 2012

The essential role of complement in antibody-mediated resistance to Salmonella

scientific article published on 10 October 2018

The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children

scientific article

The stability of complement-mediated bactericidal activity in human serum against Salmonella

scientific article

Three Epidemics of Invasive Multidrug-Resistant Salmonella Bloodstream Infection in Blantyre, Malawi, 1998-2014.

scientific article published in November 2015

Thymus, thymoma, and specific T cells in myasthenia gravis.

scientific article published in May 1998

Toll-Like Receptor Activation by Generalized Modules for Membrane Antigens from Lipid A Mutants of Salmonella enterica Serovars Typhimurium and Enteritidis

scientific article published on 10 February 2016

Typhoid Conjugate Vaccines and Enteric Fever Control: Where to Next?

scientific article published on 01 July 2020

Vaccine-Derived Poliomyelitis 12 Years after Infection ⬇️

scholarly article published 6 October 2011 in The New England Journal of Medicine

Vaccines against invasive Salmonella disease: current status and future directions

scientific article

Vaccines against poverty

scientific article

Vaccines for low-income countries ⬇️

scientific article published on June 10, 2013

What threat from persistent vaccine-related poliovirus?

scientific article published in The Lancet

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