List of works - Andis Graudins

"Punk" rock can be bad for you: a case of surgical emphysema from a "punk" rocker's leather jacket

scientific article

A randomised controlled trial of paracetamol and ibuprofen with or without codeine or oxycodone as initial analgesia for adults with moderate pain from limb injury

scientific article published on 7 September 2016

A retrospective descriptive study of the characteristics of deliberate self-poisoning patients with single or repeat presentations to an Australian emergency medicine network in a one year period.

scientific article

Accuracy of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity in modified-release paracetamol overdose.

scientific article published on 15 February 2017

Accuracy of the paracetamol-aminotransferase product to predict hepatotoxicity in paracetamol overdose treated with a 2-bag acetylcysteine regimen

scientific article published on 31 July 2017

Acetaminophen protein adduct formation following low-dose acetaminophen exposure: comparison of immediate-release vs extended-release formulations.

scientific article published on 28 September 2012

Activated Charcoal Decreases the Risk of QT Prolongation After Citalopram Overdose

scientific article published on 23 August 2007

Acute dystonia in a child associated with therapeutic ingestion of a dextromethorphan containing cough and cold syrup

scientific article published on January 1996

Adolescent deliberate self-poisoning in South-East Melbourne

scientific article

An assessment of the in vivo effects of intravenous lipid emulsion on blood drug concentration and haemodynamics following oro-gastric amitriptyline overdose.

scientific article published on 26 March 2013

An in vitro analysis of the effects of intravenous lipid emulsion on free and total local anaesthetic concentrations in human blood and plasma.

scientific article

Analysis of an 8-hour acetylcysteine infusion protocol for repeated supratherapeutic ingestion (RSTI) of paracetamol

scientific article published on 16 August 2017

Anti-Xa activity in apixaban overdose: a case report.

scientific article published on 20 July 2016

Antiemetic treatment in the emergency department: Patient opinions and expectations

scientific article

Antivenoms for the Treatment of Spider Envenomation

Arachnid toxinology in Australia: from clinical toxicology to potential applications

scientific article

Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies.

scientific article

Characteristics of Aboriginal and Torres Strait Islander presentations to three Victorian emergency departments.

scientific article published on 8 November 2013

Characteristics of frequent emergency department presenters to an Australian emergency medicine network

scientific article

Characteristics of paediatric frequent presenters to an Australian emergency medicine network.

scientific article published on 21 June 2013

Cloning and activity of a novel α-latrotoxin from red-back spider venom

scientific article

Comparative hemodynamic effects of levosimendan alone and in conjunction with 4-aminopyridine or calcium chloride in a rodent model of severe verapamil poisoning.

scientific article published on June 2010

Comparative pharmacokinetics of Panadol Extend and immediate-release paracetamol in a simulated overdose model

scientific article published on 01 August 2006

Cross-reactivity of Sydney funnel-web spider antivenom: neutralization of the in vitro toxicity of other Australian funnel-web (Atrax and Hadronyche) spider venoms.

scientific article

Delayed neurologic sequelae resulting from epidemic diethylene glycol poisoning

scientific article published in January 2005

Deliberate Self-poisoning with a Lethal Dose of Pentobarbital with Confirmatory Serum Drug Concentrations: Survival After Cardiac Arrest with Supportive Care

scientific article published on 02 August 2018

Deliberate self-poisoning presenting to an emergency medicine network in South-East melbourne: a descriptive study.

scientific article

Diagnosis and treatment of sulfonylurea-induced hyperinsulinemic hypoglycemia

scientific article published on 01 January 1997

Do antiemetic drugs benefit adult emergency department patients with nausea? The literature says no, but is it right?

scientific article published in August 2017

Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption

scientific article published on 7 August 2009

Efficacy of Australian red-back spider (Latrodectus hasselti) antivenom in the treatment of clinical envenomation by the cupboard spider Steatoda capensis (Theridiidae).

scientific article

Elderly patients with suspected chronic digoxin toxicity: A comparison of clinical characteristics of patients receiving and not receiving digoxin-Fab

scientific article published on 8 January 2018

Erratum to: FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

scholarly article published in Inflammopharmacology

Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning

scientific article

Extended-release quetiapine overdose is associated with delayed onset of toxicity compared to immediate-release quetiapine overdose

scientific article published on 28 November 2018

FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

scientific article published on 7 March 2010

Fluoxetine-induced cardiotoxicity with response to bicarbonate therapy

scientific article published on September 1997

Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity

scientific article published on 22 March 2018

Improving the management of the paracetamol poisoned patient

scientific article published on 20 July 2019

In reply

scientific article published on 16 November 2017

Intermittent haemodialysis and sustained low-efficiency dialysis (SLED) for acute theophylline toxicity

scientific article published on 21 March 2015

Intrathecal Clonidine Pump Failure Causing Acute Withdrawal Syndrome With 'Stress-Induced' Cardiomyopathy

scientific article published on 14 September 2015

Letter regarding levosimendan in a rat model of severe verapamil poisoning

scientific article published on September 2009

Levosimendan does not improve cardiac output or blood pressure in a rodent model of propranolol toxicity when administered using various dosing regimens

scientific article published on 14 March 2012

Levosimendan infusion improves cardiac output but not blood pressure in a rodent model of severe metoprolol toxicity

scientific article published on 16 January 2012

Management of cardiac arrest following poisoning.

scientific article published on 12 January 2011

Management of mental health patients in Victorian emergency departments: A 10 year follow-up study

scientific article

Methodology for AACT evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning

scientific article published on 10 June 2015

Methylene blue used in the treatment of refractory shock resulting from drug poisoning.

scientific article published on 24 December 2013

MicroRNA from a 12-h versus 20-h acetylcysteine infusion for paracetamol overdose

scientific article published on 06 March 2019

N-acetylcysteine regimens for paracetamol overdose: Time for a change?

scientific article

Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine.

scientific article published on March 2009

Occult lead poisoning from Ayurvedic medicine produced, prescribed and purchased in India

scientific article published in February 2011

Off-label and unlicenced medicine administration to paediatric emergency department patients

scientific article published on 24 June 2015

Outcome at 30 days for low-risk chest pain patients assessed using an accelerated diagnostic pathway in the emergency department

scientific article

Overdose of extended-release acetaminophen

scientific article published on 01 July 1995

Overdose with modified-release paracetamol (Panadol Osteo®) presenting to a metropolitan emergency medicine network: a case series.

scientific article published on 17 June 2014

Oxycodone/naloxone preparation can cause acute withdrawal symptoms when misused parenterally or taken orally.

scientific article published on 25 June 2015

Paracetamol metabolite concentrations following low risk overdose treated with an abbreviated 12-h versus 20-h acetylcysteine infusion

scientific article published on 19 November 2018

Paracetamol poisoning in adolescents in an Australian setting: not quite adults.

scientific article published on 5 March 2015

Paracetamol toxicity: what would be the implications of a change in Australian treatment guidelines?

scientific article published on April 2014

Pharmacokinetic modelling of modified acetylcysteine infusion regimens used in the treatment of paracetamol poisoning

scientific article published on 17 June 2017

Population pharmacokinetics of intravenous, intramuscular, and intranasal naloxone in human volunteers

scientific article published on August 2008

Prolonged coma resulting from massive levothyroxine overdose and the utility of N-terminal prohormone brain natriuretic peptide (NT-proBNP)

scientific article published on 28 November 2018

Randomized placebo-controlled trial of droperidol and ondansetron for adult emergency department patients with nausea

scientific article published on 04 December 2018

Red-back spider (Latrodectus hasselti) antivenom prevents the toxicity of widow spider venoms.

scientific article

Review article: A primer for clinical researchers in the emergency department: Part 6. Measuring what matters: Core outcome sets in emergency medicine research.

scientific article published on 2 April 2018

Review article: Up (to) date for Australian Toxicology and Toxinology guidelines

scientific article published on 29 October 2020

Risk prediction of hepatotoxicity in paracetamol poisoning

scientific article

Simplification of the standard three-bag intravenous acetylcysteine regimen for paracetamol poisoning results in a lower incidence of adverse drug reactions

scientific article published on 23 November 2015

Spiders of medical importance in the Asia-Pacific: atracotoxin, latrotoxin and related spider neurotoxins

scientific article

Sub-dissociative dose intranasal ketamine for limb injury pain in children in the emergency department: a pilot study.

scientific article published on 20 March 2013

Sub-dissociative-dose intranasal ketamine for moderate to severe pain in adult emergency department patients.

scientific article published on 8 April 2014

Summary statement: new guidelines for the management of paracetamol poisoning in Australia and New Zealand

article

Systematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity

scientific article published on 6 February 2016

The Australasian Clinical Toxicology Investigators Collaboration randomized trial of different loading infusion rates of N-acetylcysteine

scientific article published in April 2005

The NACSTOP Trial: A Multicenter, Cluster-Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose

scientific article published on 19 January 2019

The PICHFORK (Pain InCHildren Fentanyl OR Ketamine) trial comparing the efficacy of intranasal ketamine and fentanyl in the relief of moderate to severe pain in children with limb injuries: study protocol for a randomized controlled trial

scientific article published on 10 July 2013

The PICHFORK (Pain in Children Fentanyl or Ketamine) trial: a randomized controlled trial comparing intranasal ketamine and fentanyl for the relief of moderate to severe pain in children with limb injuries.

scientific article published on 18 November 2014

The Use of Peritoneal Dialysis in Phenobarbitone Toxicity in a Critically Unwell Neonate.

scientific article published on 24 November 2017

The care of older children when a sibling is born

scientific article published on 01 February 1985

The comparative pharmacokinetics of modified-release and immediate-release paracetamol in a simulated overdose model

scientific article published on December 2010

The effects of fructose-1,6-diphosphate on haemodynamic parameters and survival in a rodent model of propranolol and verapamil poisoning

scientific article published on August 2012

The pharmacokinetics of intranasal droperidol in volunteers characterised via population modelling

scientific article published on 04 December 2018

The use of sustained low efficiency dialysis (SLED) in massive paracetamol overdose

scientific article published on 16 August 2017

Treatment of experimental verapamil poisoning with levosimendan utilizing a rodent model of drug toxicity

scientific article published in January 2008

Treatment of the serotonin syndrome with cyproheptadine.

scientific article

Treatments for Latrodectism-A Systematic Review on Their Clinical Effectiveness.

scientific article

Visual analog scale rating change cut-offs for detection of improvement in nausea severity

scientific article published on 05 April 2019

α-Elapitoxin-Aa2a, a long-chain snake α-neurotoxin with potent actions on muscle (α1)(2)βγδ nicotinic receptors, lacks the classical high affinity for neuronal α7 nicotinic receptors

scientific article published on 13 October 2010

List of works by Andis Graudins

"Punk" rock can be bad for you: a case of surgical emphysema from a "punk" rocker's leather jacket

A randomised controlled trial of paracetamol and ibuprofen with or without codeine or oxycodone as initial analgesia for adults with moderate pain from limb injury

A retrospective descriptive study of the characteristics of deliberate self-poisoning patients with single or repeat presentations to an Australian emergency medicine network in a one year period.

Accuracy of the paracetamol-aminotransferase multiplication product to predict hepatotoxicity in modified-release paracetamol overdose.

Accuracy of the paracetamol-aminotransferase product to predict hepatotoxicity in paracetamol overdose treated with a 2-bag acetylcysteine regimen

Acetaminophen protein adduct formation following low-dose acetaminophen exposure: comparison of immediate-release vs extended-release formulations.

Activated Charcoal Decreases the Risk of QT Prolongation After Citalopram Overdose

Acute dystonia in a child associated with therapeutic ingestion of a dextromethorphan containing cough and cold syrup

Adolescent deliberate self-poisoning in South-East Melbourne

An assessment of the in vivo effects of intravenous lipid emulsion on blood drug concentration and haemodynamics following oro-gastric amitriptyline overdose.

An in vitro analysis of the effects of intravenous lipid emulsion on free and total local anaesthetic concentrations in human blood and plasma.

Analysis of an 8-hour acetylcysteine infusion protocol for repeated supratherapeutic ingestion (RSTI) of paracetamol

Anti-Xa activity in apixaban overdose: a case report.

Antiemetic treatment in the emergency department: Patient opinions and expectations

Antivenoms for the Treatment of Spider Envenomation

Arachnid toxinology in Australia: from clinical toxicology to potential applications

Calcium channel antagonist and beta-blocker overdose: antidotes and adjunct therapies.

Characteristics of Aboriginal and Torres Strait Islander presentations to three Victorian emergency departments.

Characteristics of frequent emergency department presenters to an Australian emergency medicine network

Characteristics of paediatric frequent presenters to an Australian emergency medicine network.

Cloning and activity of a novel α-latrotoxin from red-back spider venom

Comparative hemodynamic effects of levosimendan alone and in conjunction with 4-aminopyridine or calcium chloride in a rodent model of severe verapamil poisoning.

Comparative pharmacokinetics of Panadol Extend and immediate-release paracetamol in a simulated overdose model

Cross-reactivity of Sydney funnel-web spider antivenom: neutralization of the in vitro toxicity of other Australian funnel-web (Atrax and Hadronyche) spider venoms.

Delayed neurologic sequelae resulting from epidemic diethylene glycol poisoning

Deliberate Self-poisoning with a Lethal Dose of Pentobarbital with Confirmatory Serum Drug Concentrations: Survival After Cardiac Arrest with Supportive Care

Deliberate self-poisoning presenting to an emergency medicine network in South-East melbourne: a descriptive study.

Diagnosis and treatment of sulfonylurea-induced hyperinsulinemic hypoglycemia

Do antiemetic drugs benefit adult emergency department patients with nausea? The literature says no, but is it right?

Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption

Efficacy of Australian red-back spider (Latrodectus hasselti) antivenom in the treatment of clinical envenomation by the cupboard spider Steatoda capensis (Theridiidae).

Elderly patients with suspected chronic digoxin toxicity: A comparison of clinical characteristics of patients receiving and not receiving digoxin-Fab

Erratum to: FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning

Extended-release quetiapine overdose is associated with delayed onset of toxicity compared to immediate-release quetiapine overdose

FDA proposals to limit the hepatotoxicity of paracetamol (acetaminophen): are they reasonable?

Fluoxetine-induced cardiotoxicity with response to bicarbonate therapy

Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity

Improving the management of the paracetamol poisoned patient

In reply

Intermittent haemodialysis and sustained low-efficiency dialysis (SLED) for acute theophylline toxicity

Intrathecal Clonidine Pump Failure Causing Acute Withdrawal Syndrome With 'Stress-Induced' Cardiomyopathy

Letter regarding levosimendan in a rat model of severe verapamil poisoning

Levosimendan does not improve cardiac output or blood pressure in a rodent model of propranolol toxicity when administered using various dosing regimens

Levosimendan infusion improves cardiac output but not blood pressure in a rodent model of severe metoprolol toxicity

Management of cardiac arrest following poisoning.

Management of mental health patients in Victorian emergency departments: A 10 year follow-up study

Methodology for AACT evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning

Methylene blue used in the treatment of refractory shock resulting from drug poisoning.

MicroRNA from a 12-h versus 20-h acetylcysteine infusion for paracetamol overdose

N-acetylcysteine regimens for paracetamol overdose: Time for a change?

Neuroleptic malignant syndrome developing after acute overdose with olanzapine and chlorpromazine.

Occult lead poisoning from Ayurvedic medicine produced, prescribed and purchased in India

Off-label and unlicenced medicine administration to paediatric emergency department patients

Outcome at 30 days for low-risk chest pain patients assessed using an accelerated diagnostic pathway in the emergency department

Overdose of extended-release acetaminophen

Overdose with modified-release paracetamol (Panadol Osteo®) presenting to a metropolitan emergency medicine network: a case series.

Oxycodone/naloxone preparation can cause acute withdrawal symptoms when misused parenterally or taken orally.

Paracetamol metabolite concentrations following low risk overdose treated with an abbreviated 12-h versus 20-h acetylcysteine infusion

Paracetamol poisoning in adolescents in an Australian setting: not quite adults.

Paracetamol toxicity: what would be the implications of a change in Australian treatment guidelines?

Pharmacokinetic modelling of modified acetylcysteine infusion regimens used in the treatment of paracetamol poisoning

Population pharmacokinetics of intravenous, intramuscular, and intranasal naloxone in human volunteers

Prolonged coma resulting from massive levothyroxine overdose and the utility of N-terminal prohormone brain natriuretic peptide (NT-proBNP)

Randomized placebo-controlled trial of droperidol and ondansetron for adult emergency department patients with nausea

Red-back spider (Latrodectus hasselti) antivenom prevents the toxicity of widow spider venoms.

Review article: A primer for clinical researchers in the emergency department: Part 6. Measuring what matters: Core outcome sets in emergency medicine research.

Review article: Up (to) date for Australian Toxicology and Toxinology guidelines

Risk prediction of hepatotoxicity in paracetamol poisoning

Simplification of the standard three-bag intravenous acetylcysteine regimen for paracetamol poisoning results in a lower incidence of adverse drug reactions

Spiders of medical importance in the Asia-Pacific: atracotoxin, latrotoxin and related spider neurotoxins

Sub-dissociative dose intranasal ketamine for limb injury pain in children in the emergency department: a pilot study.

Sub-dissociative-dose intranasal ketamine for moderate to severe pain in adult emergency department patients.

Summary statement: new guidelines for the management of paracetamol poisoning in Australia and New Zealand

Systematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity

The Australasian Clinical Toxicology Investigators Collaboration randomized trial of different loading infusion rates of N-acetylcysteine

The NACSTOP Trial: A Multicenter, Cluster-Controlled Trial of Early Cessation of Acetylcysteine in Acetaminophen Overdose

The PICHFORK (Pain InCHildren Fentanyl OR Ketamine) trial comparing the efficacy of intranasal ketamine and fentanyl in the relief of moderate to severe pain in children with limb injuries: study protocol for a randomized controlled trial

The PICHFORK (Pain in Children Fentanyl or Ketamine) trial: a randomized controlled trial comparing intranasal ketamine and fentanyl for the relief of moderate to severe pain in children with limb injuries.