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List of works by Manuela E. Gomes

3D Bioprinting of Miniaturized Tissues Embedded in Self‐Assembled Nanoparticle‐Based Fibrillar Platforms

scientific article published in 2021

3D Mimicry of Native-Tissue-Fiber Architecture Guides Tendon-Derived Cells and Adipose Stem Cells into Artificial Tendon Constructs.

scientific article published on 20 June 2017

A Radially Organized Multipatterned Device as a Diagnostic Tool for the Screening of Topographies in Tissue Engineering Biomaterials.

scientific article

A Textile Platform Using Continuous Aligned and Textured Composite Microfibers to Engineer Tendon-to-Bone Interface Gradient Scaffolds

scientific article published on 13 June 2019

A cartilage tissue engineering approach combining starch-polycaprolactone fibre mesh scaffolds with bovine articular chondrocytes

scientific article published in February 2007

A new approach based on injection moulding to produce biodegradable starch-based polymeric scaffolds: morphology, mechanical and degradation behaviour

scientific article published on 01 May 2001

A new route to produce starch-based fiber mesh scaffolds by wet spinning and subsequent surface modification as a way to improve cell attachment and proliferation

scientific article

A novel bidirectional continuous perfusion bioreactor for the culture of large-sized bone tissue-engineered constructs.

scientific article published on 17 May 2013

A novel method for the isolation of subpopulations of rat adipose stem cells with different proliferation and osteogenic differentiation potentials

scientific article published on 26 January 2011

A tissue engineering approach for periodontal regeneration based on a biodegradable double-layer scaffold and adipose-derived stem cells.

scientific article published on 22 April 2014

Additively Manufactured Device for Dynamic Culture of Large Arrays of 3D Tissue Engineered Constructs

scientific article published on 26 February 2015

Adipose tissue-derived stem cells and their application in bone and cartilage tissue engineering

scientific article published on June 2009

Amniotic fluid-derived stem cells as a cell source for bone tissue engineering

scientific article published on 14 August 2012

Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffolds

scientific article

An automated two-phase system for hydrogel microbead production.

scientific article published on 23 August 2012

An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine

scientific article published on 24 February 2013

Assessing the repair of critical size bone defects performed in a goat tibia model using tissue-engineered constructs cultured in a bidirectional flow perfusion bioreactor.

scientific article published on 9 January 2014

Assessment of bone healing ability of calcium phosphate cements loaded with platelet lysate in rat calvarial defects

scientific article published on 16 September 2016

Asymmetric PDLLA membranes containing Bioglass® for guided tissue regeneration: characterization and in vitro biological behavior

scientific article published on 17 February 2013

Automating the processing steps for obtaining bone tissue-engineered substitutes: from imaging tools to bioreactors

scientific article published on 31 July 2014

Bi-directional modulation of cellular interactions in an in vitro co-culture model of tendon-to-bone interface

article

Bilayered constructs aimed at osteochondral strategies: The influence of medium supplements in the osteogenic and chondrogenic differentiation of amniotic fluid-derived stem cells

scientific article published on 14 April 2012

Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells

scientific article published on 13 May 2013

Bioactive starch-based scaffolds and human adipose stem cells are a good combination for bone tissue engineering

scientific article published on 29 May 2012

Biodegradable nanomats produced by electrospinning: expanding multifunctionality and potential for tissue engineering.

scientific article published on March 2007

Biofabrication of customized bone grafts by combination of additive manufacturing and bioreactor knowhow

scientific article

Biological evaluation of intervertebral disc cells in different formulations of gellan gum-based hydrogels

scientific article published on 07 December 2012

Bone marrow stromal cells on a three-dimensional bioactive fiber mesh undergo osteogenic differentiation in the absence of osteogenic media supplements: the effect of silanol groups

scientific article published on 4 June 2014

Bone turnover markers for early detection of fracture healing disturbances: A review of the scientific literature

scientific article published on 15 May 2015

Carrageenan-based hydrogels for the controlled delivery of PDGF-BB in bone tissue engineering applications

scientific article published in June 2009

Cartilage tissue engineering using electrospun PCL nanofiber meshes and MSCs

scientific article published on 24 November 2010

Cell Delivery Systems Using Alginate–Carrageenan Hydrogel Beads and Fibers for Regenerative Medicine Applications

scientific article published on 13 October 2011

Cell adhesion and proliferation onto chitosan-based membranes treated by plasma surface modification

scientific article

Cell engineering by the internalization of bioinstructive micelles for enhanced bone regeneration

scientific article

Cell-laden composite suture threads for repairing damaged tendons.

scientific article published on 8 November 2017

Cellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell response

scientific article published on 21 May 2020

Chitosan microparticles as injectable scaffolds for tissue engineering

scientific article published in August 2008

Chitosan-chondroitin sulphate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine

scientific article published on 8 June 2012

Chitosan/bioactive glass nanoparticle composite membranes for periodontal regeneration

article

Chondrogenic phenotype of different cells encapsulated in κ-carrageenan hydrogels for cartilage regeneration strategies

scientific article published on 18 March 2012

Chondrogenic potential of injectable κ-carrageenan hydrogel with encapsulated adipose stem cells for cartilage tissue-engineering applications

scientific article published on January 9, 2013

Chondrogenic potential of two hASCs subpopulations loaded onto gellan gum hydrogel evaluated in a nude mice model.

scientific article published on September 2013

Combinatorial Effect of Silicon and Calcium Release from Starch-Based Scaffolds on Osteogenic Differentiation of Human Adipose Stem Cells

Comparison of the cytotoxicity of molybdenum as powder and as alloying element in a niobium-molybdenum alloy

scientific article published in December 1998

Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch polycaprolactone scaffolds

scientific article

Contributions and future perspectives on the use of magnetic nanoparticles as diagnostic and therapeutic tools in the field of regenerative medicine

scientific article published on July 2013

Controlled release strategies for bone, cartilage, and osteochondral engineering--Part I: recapitulation of native tissue healing and variables for the design of delivery systems

scientific article published on 19 February 2013

Controlled release strategies for bone, cartilage, and osteochondral engineering--Part II: challenges on the evolution from single to multiple bioactive factor delivery

scientific article published on 30 January 2013

Crosstalk between adipose stem cells and tendon cells reveals a temporal regulation of tenogenesis by matrix deposition and remodeling

scientific article published on 7 December 2017

Cryopreservation of cell laden natural origin hydrogels for cartilage regeneration strategies

Cryopreservation of cell/scaffold tissue-engineered constructs

scientific article published on 16 July 2012

Current strategies for osteochondral regeneration: from stem cells to pre-clinical approaches

scientific article published on 06 May 2011

Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions

scientific article published in July 2001

Decellularized kidney extracellular matrix bioinks recapitulate renal 3D microenvironment in vitro

scientific article published in 2021

Design and characterization of a biodegradable double-layer scaffold aimed at periodontal tissue-engineering applications.

scientific article

Development of Inhalable Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in Microparticulate System for Antituberculosis Drug Delivery

article

Development of Injectable Hyaluronic Acid/Cellulose Nanocrystals Bionanocomposite Hydrogels for Tissue Engineering Applications.

scientific article published on 24 June 2015

Development of a bioactive glass fiber reinforced starch-polycaprolactone composite

article

Development of an Injectable Calcium Phosphate/Hyaluronic Acid Microparticles System for Platelet Lysate Sustained Delivery Aiming Bone Regeneration

scientific article published on 2 August 2016

Development of micropatterned surfaces of poly(butylene succinate) by micromolding for guided tissue engineering

article

Development of new chitosan/carrageenan nanoparticles for drug delivery applications

scientific article published on March 2010

Differentiation of mesenchymal stem cells in chitosan scaffolds with double micro and macroporosity.

scientific article

Distinct stem cells subpopulations isolated from human adipose tissue exhibit different chondrogenic and osteogenic differentiation potential

scientific article published in March 2011

Dynamic culture of osteogenic cells in biomimetically coated poly(caprolactone) nanofibre mesh constructs

scientific article

Effect of anatomical origin and cell passage number on the stemness and osteogenic differentiation potential of canine adipose-derived stem cells.

scientific article published in December 2012

Effect of flow perfusion conditions in the chondrogenic differentiation of bone marrow stromal cells cultured onto starch based biodegradable scaffolds

scientific article published on 3 December 2010

Effects of hypergravity on the angiogenic potential of endothelial cells.

scientific article published on November 2016

Encapsulation of adipose-derived stem cells and transforming growth factor-β1 in carrageenan-based hydrogels for cartilage tissue engineering

scholarly article by Pedro M Rocha et al published September 2011 in Journal of Bioactive and Compatible Polymers

Endothelial cell colonization and angiogenic potential of combined nano- and micro-fibrous scaffolds for bone tissue engineering

scientific article published on 15 August 2008

Engineering Enriched Microenvironments with Gradients of Platelet Lysate in Hydrogel Fibers

scientific article published on 20 May 2016

Engineering next-generation bioinks with nanoparticles: moving from reinforcement fillers to multifunctional nanoelements

scientific article published in 2021

Engineering tendon and ligament tissues: present developments towards successful clinical products

scientific article published on April 12, 2012

Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming

scientific article published on 12 June 2012

Enhancing the Biomechanical Performance of Anisotropic Nanofibrous Scaffolds in Tendon Tissue Engineering: Reinforcement with Cellulose Nanocrystals.

scientific article published on 5 April 2016

Evaluation of a starch-based double layer scaffold for bone regeneration in a rat model

article

Evaluation of bone turnover markers and serum minerals variations for predicting fracture healing versus non-union processes in adult sheep as a model for orthopedic research

scientific article published on 17 May 2017

Evaluation of hematology, general serum biochemistry, bone turnover markers and bone marrow cytology in a glucocorticoid treated ovariectomized sheep model for osteoporosis research

scientific article published on 07 December 2020

Evaluation of the in vitro and in vivo biocompatibility of carrageenan-based hydrogels

scientific article published on 28 January 2014

Exploring platelet lysate hydrogel-coated suture threads as biofunctional composite living fibers for cell delivery in tissue repair

scientific article published on 05 April 2019

Exploring the Potential of Starch/Polycaprolactone Aligned Magnetic Responsive Scaffolds for Tendon Regeneration

scientific article published on 25 November 2015

Expression, purification and osteogenic bioactivity of recombinant human BMP-4, -9, -10, -11 and -14.

scientific article published on 4 October 2008

Fabrication of endothelial cell-laden carrageenan microfibers for microvascularized bone tissue engineering applications

scientific article published on 8 July 2014

From nano- to macro-scale: nanotechnology approaches for spatially controlled delivery of bioactive factors for bone and cartilage engineering

scientific article published on July 2012

Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering

scientific article published on 26 June 2015

Human adipose tissue-derived SSEA-4 subpopulation multi-differentiation potential towards the endothelial and osteogenic lineages

scientific article

Human platelet lysate-based nanocomposite bioink for bioprinting hierarchical fibrillar structures

scientific article published on 27 November 2019

Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior

scientific article published on 01 September 2018

Hybrid 3D structure of poly(d,l-lactic acid) loaded with chitosan/chondroitin sulfate nanoparticles to be used as carriers for biomacromolecules in tissue engineering

scholarly article by Vítor E. Santo et al published September 2010 in Journal of Supercritical Fluids

In situ functionalization of wet-spun fibre meshes for bone tissue engineering

scientific article published on 01 February 2011

In vitro and in vivo assessment of magnetically actuated biomaterials and prospects in tendon healing

scientific article published on 14 April 2016

In vitro evaluation of osteoconductive starch based scaffolds under dynamic conditions

In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor

scientific article published in January 2006

In vitro temporal HIF-mediated deposition of osteochondrogenic matrix governed by hypoxia and osteogenic factors synergy

scientific article published on 05 November 2020

Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor

scientific article

Injectable gellan gum hydrogels with autologous cells for the treatment of rabbit articular cartilage defects

scientific article published in September 2010

Interactive endothelial phenotype maintenance and osteogenic differentiation of adipose tissue stromal vascular fraction SSEA-4+ -derived cells

scientific article published on 29 October 2015

Layer-by-layer assembled cell instructive nanocoatings containing platelet lysate

scientific article published on 10 February 2015

Macroporous hydroxyapatite scaffolds for bone tissue engineering applications: physicochemical characterization and assessment of rat bone marrow stromal cell viability.

scientific article

Magnetic Nanocomposite Hydrogels for Tissue Engineering: Design Concepts and Remote Actuation Strategies to Control Cell Fate

scientific article published on 06 January 2021

Magnetic responsive cell-based strategies for diagnostics and therapeutics

scholarly article by Ana I Gonçalves et al published 6 August 2018 in Biomedical Materials

Magnetic triggers in biomedical applications - prospects for contact free cell sensing and guidance

scientific article published on 07 January 2021

Magnetically-Responsive Hydrogels for Modulation of Chondrogenic Commitment of Human Adipose-Derived Stem Cells

scientific article published on 25 January 2016

Magneto-mechanical actuation of magnetic responsive fibrous scaffolds boosts tenogenesis of human adipose stem cells

scientific article published on 01 October 2019

Magnetotherapy: The quest for tendon regeneration

scientific article

Marine algae sulfated polysaccharides for tissue engineering and drug delivery approaches

scientific article

Microengineered Multicomponent Hydrogel Fibers: Combining Polyelectrolyte Complexation and Microfluidics

article

Microfabricated photocrosslinkable polyelectrolyte-complex of chitosan and methacrylated gellan gum

scientific article published on September 2012

Modified Gellan Gum hydrogels with tunable physical and mechanical properties

scientific article

Molecularly Imprinted Intelligent Scaffolds for Tissue Engineering Applications

scientific article

Multifunctional magnetic-responsive hydrogels to engineer tendon-to-bone interface

scientific article published on 11 June 2017

Nano- and micro-fiber combined scaffolds: a new architecture for bone tissue engineering.

scientific article published on December 2005

Natural Polymers in tissue engineering applications

scholarly article published 2008

Natural assembly of platelet lysate-loaded nanocarriers into enriched 3D hydrogels for cartilage regeneration

scientific article published on 17 March 2015

Novel genipin-cross-linked chitosan/silk fibroin sponges for cartilage engineering strategies

scientific article published on 25 September 2008

Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells

scientific article published on 30 August 2006

Novel method for the isolation of adipose stem cells (ASCs).

scientific article

Osteogenic differentiation of two distinct subpopulations of human adipose-derived stem cells: an in vitro and in vivo study

scientific article published on 4 February 2011

Periodontal tissue engineering strategies based on nonoral stem cells

scientific article

Photocrosslinkable kappa-carrageenan hydrogels for tissue engineering applications.

scientific article published on 27 December 2012

Plasma surface modification of chitosan membranes: characterization and preliminary cell response studies

scientific article

Platelet lysate-based pro-angiogenic nanocoatings

scientific article published on 17 December 2015

Preface

Production and characterization of hyaluronic acid microparticles for the controlled delivery of growth factors using a spray/dehydration method

article

Proliferation and differentiation of goat bone marrow stromal cells in 3D scaffolds with tunable hydrophilicity.

scientific article published in October 2009

Pulsed Electromagnetic Field Modulates Tendon Cells Response in IL-1β-Conditioned Environment

scientific article published on 10 December 2019

Rapid vascularization of starch-poly(caprolactone) in vivo by outgrowth endothelial cells in co-culture with primary osteoblasts

article

Response of micro- and macrovascular endothelial cells to starch-based fiber meshes for bone tissue engineering

scientific article published on September 2006

Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep

scientific article published in June 2014

Silk hydrogels from non-mulberry and mulberry silkworm cocoons processed with ionic liquids

scientific article

Starch-poly(epsilon-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: structure, mechanical properties and degradation behaviour

scientific article

Studies of P(L/D)LA 96/4 non-woven scaffolds and fibres; properties, wettability and cell spreading before and after intrusive treatment methods

scientific article published on 3 February 2007

Synergistic effect of scaffold composition and dynamic culturing environment in multilayered systems for bone tissue engineering

scientific article published on March 27, 2012

The Role of a Platelet Lysate-Based Compartmentalized System as a Carrier of Cells and Platelet-Origin Cytokines for Periodontal Tissue Regeneration

scientific article published on 8 September 2016

The effect of differentiation stage of amniotic fluid stem cells on bone regeneration

scientific article published on 05 June 2012

The effect of storage time on adipose-derived stem cell recovery from human lipoaspirates

scientific article

The osteogenic differentiation of SSEA-4 sub-population of human adipose derived stem cells using silicate nanoplatelets

scientific article published on 12 August 2014

The potential of cellulose nanocrystals in tissue engineering strategies.

scientific article

The role of lipase and alpha-amylase in the degradation of starch/poly(epsilon-caprolactone) fiber meshes and the osteogenic differentiation of cultured marrow stromal cells

scientific article

Tissue Engineering and Regenerative Medicine: New Trends and Directions-A Year in Review

scientific article

Tissue engineering: key elements and some trends

scientific article published in August 2004

Tissue-engineered constructs based on SPCL scaffolds cultured with goat marrow cells: functionality in femoral defects

scientific article published in January 2011

Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: nude mice calvarial defect in vivo study

scientific article published on 12 October 2013

Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine

scholarly article by Ana Rita Duarte et al published July 2013 in Journal of Supercritical Fluids

Use of animal protein-free products for passaging adherent human adipose-derived stromal/stem cells

scientific article published on 03 January 2011

Use of perfusion bioreactors and large animal models for long bone tissue engineering

scientific article published on 11 October 2013

Xenofree enzymatic products for the isolation of human adipose-derived stromal/stem cells

scientific article published on 31 January 2013